Page last updated: 2024-08-23

simvastatin and Ventricular Dysfunction, Left

simvastatin has been researched along with Ventricular Dysfunction, Left in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's10 (55.56)29.6817
2010's6 (33.33)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Haczkiewicz-Leśniak, K; Kwiatkowska, J; Piasecki, T; Podhorska-Okołów, M; Sapa-Wojciechowska, A; Skrzypiec-Spring, M; Szeląg, A1
Adams, ME; Bible, KL; Froehner, SC; Kim, MJ; Regnier, M; Whitehead, NP1
Huang, XH; Hui, RT; Liu, G; Lu, J; Xu, YL; Zheng, XX1
Chai, CY; Chen, IC; Chen, IJ; Chou, SH; Dai, ZK; Tan, MS; Wu, BN; Yeh, JL1
Cioffi, G; Cramariuc, D; Devereux, RB; Gerdts, E; Ray, S; Rieck, AE; Staal, EM; Wachtell, K1
Dumesnil, JG; Pibarot, P1
Adachi, S; Hirao, K; Isobe, M; Ito, H; Maejima, Y; Nobori, K; Ono, Y; Suzuki, J1
Boman, K; Devereux, RB; Egstrup, K; Gohlke-Baerwolf, C; Greve, AM; Kesäniemi, YA; Køber, L; Nienaber, C; Ray, S; Rossebø, AB; Wachtell, K; Willenheimer, R1
Armendaris, MK; Beck, AL; D'Avila, LB; Netto, FM; Otto, ME; Sposito, AC1
Iqbal, P; Jamil, S1
Bonow, RO; Gheorghiade, M; Kim, RJ; Klein, L; Stone, NJ1
Ahn, YK; Cho, JG; Hong, SN; Hong, YJ; Hur, SH; Hyun, DW; Jeong, MH; Kang, DG; Kang, JC; Kim, JH; Kim, KB; Kim, KH; Kim, W; Lee, SH; Lee, YS; Lim, SY; Park, HW; Park, JC; Yun, KH1
Elrod, JW; Greer, JJ; Jones, SP; Kakkar, AK; Lefer, DJ; Watson, LJ1
Ahn, Y; Cho, JG; Hong, SN; Hong, YJ; Hwang, SH; Jeong, MH; Kang, JC; Kim, JH; Kim, KH; Lee, SR; Park, HW; Park, JC; Yun, NS1
Bauersachs, J; Fraccarollo, D; Hiss, K; Laufs, U; Ruetten, H1
Bartuś, S; Bryniarski, L; Dobrowolski, W; Dudek, D; Giszterowicz, D; Korpak-Wysocka, R; Kukla, P1
Belichard, P; Bontemps, L; de Lorgeril, M; Geyssant, A; Itti, R; Salen, P1
Jones, SP; Lefer, DJ; Trocha, SD1

Reviews

1 review(s) available for simvastatin and Ventricular Dysfunction, Left

ArticleYear
Effects of lipophilic statins for heart failure: a meta-analysis of 13 randomised controlled trials.
    Heart, lung & circulation, 2014, Volume: 23, Issue:10

    Topics: Atorvastatin; Cholesterol, LDL; Disease Progression; Heart Failure; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Quinolines; Randomized Controlled Trials as Topic; Simvastatin; Stroke Volume; Ventricular Dysfunction, Left

2014

Trials

5 trial(s) available for simvastatin and Ventricular Dysfunction, Left

ArticleYear
Low-flow aortic stenosis in asymptomatic patients: valvular-arterial impedance and systolic function from the SEAS Substudy.
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:4

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Atherosclerosis; Azetidines; Disease Progression; Double-Blind Method; Drug Combinations; Echocardiography, Doppler; Europe; Ezetimibe, Simvastatin Drug Combination; Female; Hemodynamics; Humans; Hypolipidemic Agents; Logistic Models; Male; Middle Aged; Myocardial Contraction; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; ROC Curve; Sensitivity and Specificity; Simvastatin; Systole; Treatment Outcome; United States; Ventricular Dysfunction, Left

2009
Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:3

    Topics: Aged; Angiotensin Receptor Antagonists; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Simvastatin; Treatment Outcome; Ventricular Dysfunction, Left

2011
Clinical implications of electrocardiographic left ventricular strain and hypertrophy in asymptomatic patients with aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis study.
    Circulation, 2012, Jan-17, Volume: 125, Issue:2

    Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Azetidines; Cardiovascular Diseases; Drug Therapy, Combination; Electrocardiography; Ezetimibe; Female; Follow-Up Studies; Heart Failure; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Infarction; Prognosis; Simvastatin; Ventricular Dysfunction, Left

2012
Diastolic function parameters are improved by the addition of simvastatin to enalapril-based treatment in hypertensive individuals.
    Atherosclerosis, 2012, Volume: 222, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Blood Pressure; Brazil; Chi-Square Distribution; Cholesterol; Diastole; Diuretics; Double-Blind Method; Drug Therapy, Combination; Echocardiography, Doppler; Enalapril; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Middle Aged; Prospective Studies; Regression Analysis; Simvastatin; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left

2012
Effects of lipid-lowering drugs on left ventricular function and exercise tolerance in dyslipidemic coronary patients.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:3

    Topics: Blood Pressure; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Dyspepsia; Exercise Test; Female; Fenofibrate; Fibrinogen; Heart Rate; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Patient Dropouts; Physical Endurance; Simvastatin; Stroke Volume; Treatment Outcome; Triglycerides; Ventricular Dysfunction, Left; Ventricular Function, Left

1999

Other Studies

12 other study(ies) available for simvastatin and Ventricular Dysfunction, Left

ArticleYear
HMG-CoA Reductase Inhibitor, Simvastatin Is Effective in Decreasing Degree of Myocarditis by Inhibiting Metalloproteinases Activation.
    Biomolecules, 2021, 09-28, Volume: 11, Issue:10

    Topics: Animals; Autoimmune Diseases; Cardiotonic Agents; Echocardiography; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Metalloproteases; Models, Animal; Myocarditis; Rats; Simvastatin; Ventricular Dysfunction, Left

2021
Simvastatin provides long-term improvement of left ventricular function and prevents cardiac fibrosis in muscular dystrophy.
    Physiological reports, 2019, Volume: 7, Issue:6

    Topics: Animals; Autonomic Nervous System; Calcium-Binding Proteins; Cardiomyopathies; Disease Models, Animal; Fibrosis; Heart; Heart Rate; Male; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocytes, Cardiac; Phosphorylation; Recovery of Function; Simvastatin; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2019
Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho-kinase pathway and NADPH oxidase.
    Pediatric pulmonology, 2017, Volume: 52, Issue:4

    Topics: Animals; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; NADPH Oxidases; Rats; Rats, Wistar; Reactive Oxygen Species; rho-Associated Kinases; Simvastatin; Ventricular Dysfunction, Left

2017
Aortic stenosis: look globally, think globally.
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:4

    Topics: Aortic Valve Stenosis; Atherosclerosis; Azetidines; Calcinosis; Disease Progression; Drug Combinations; Echocardiography, Doppler; Ezetimibe, Simvastatin Drug Combination; Hemodynamics; Humans; Hypolipidemic Agents; Myocardial Contraction; Predictive Value of Tests; Risk Assessment; Risk Factors; Simvastatin; Systole; Treatment Outcome; Ventricular Dysfunction, Left

2009
Rhabdomyolysis induced by a single dose of a statin.
    Heart (British Cardiac Society), 2004, Volume: 90, Issue:1

    Topics: Dyspnea; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Middle Aged; Rhabdomyolysis; Simvastatin; Ventricular Dysfunction, Left

2004
Improvement in the function of hibernating myocardium in a patient with heart failure due to coronary artery disease receiving high-dose simvastatin.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2004, Volume: 5, Issue:2

    Topics: Aged; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Myocardial Contraction; Myocardial Stunning; Simvastatin; Stroke Volume; Ventricular Dysfunction, Left

2004
Prognostic significance of simvastatin therapy in patients with ischemic heart failure who underwent percutaneous coronary intervention for acute myocardial infarction.
    The American journal of cardiology, 2005, Mar-01, Volume: 95, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; C-Reactive Protein; Coronary Angiography; Female; Fibrinogen; Humans; Hypolipidemic Agents; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Prognosis; Prospective Studies; Simvastatin; Survival Rate; Treatment Outcome; Ventricular Dysfunction, Left

2005
Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Animals; Gene Expression Regulation, Enzymologic; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Infarction; Nitric Oxide Synthase Type III; Pulmonary Edema; Severity of Illness Index; Simvastatin; Survival Rate; Ventricular Dysfunction, Left

2006
Effect of combination therapy with simvastatin and carvedilol in patients with left ventricular dysfunction complicated with acute myocardial infarction who underwent percutaneous coronary intervention.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Carbazoles; Carvedilol; Death; Disease-Free Survival; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Propanolamines; Retrospective Studies; Simvastatin; Stroke Volume; Treatment Outcome; Ventricular Dysfunction, Left

2006
Simvastatin improves left ventricular function after myocardial infarction in hypercholesterolemic rabbits by anti-inflammatory effects.
    Cardiovascular research, 2006, Dec-01, Volume: 72, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; C-Reactive Protein; Diet; Echocardiography; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Models, Animal; Myocardial Infarction; Nitric Oxide Synthase Type III; Rabbits; rac1 GTP-Binding Protein; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Simvastatin; Ventricular Dysfunction, Left

2006
[Transient left ventricular apical ballooning syndrome--a case report].
    Kardiologia polska, 2007, Volume: 65, Issue:2

    Topics: Aged; Amlodipine; Echocardiography, Doppler; Electrocardiography; Enoxaparin; Female; Humans; Simvastatin; Syndrome; Treatment Outcome; Ventricular Dysfunction, Left

2007
Pretreatment with simvastatin attenuates myocardial dysfunction after ischemia and chronic reperfusion.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:12

    Topics: Animals; Anticholesteremic Agents; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Premedication; Simvastatin; Ultrasonography; Ventricular Dysfunction, Left

2001