simvastatin has been researched along with Uterine Neoplasms in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afrin, S; Borahay, MA; El Sabeh, M; Saha, SK | 1 |
| Afrin, S; Al-Hendy, A; Ali, M; Borahay, MA; El Sabeh, M; Yang, Q | 1 |
| Afrin, S; Borahay, MA; Catherino, WH; Islam, MS; Malik, M; Patzkowsky, K; Segars, JH | 1 |
| Al-Hendy, A; Ali, M; Jackson-Bey, T | 1 |
| Borahay, M; Britten, J; Catherino, WH; Malik, M; Segars, J | 1 |
| Al-Hendy, A; Boehning, D; Borahay, MA; Kilic, GS; Motamedi, M; Sbrana, E; Vincent, K | 1 |
6 other study(ies) available for simvastatin and Uterine Neoplasms
| Article | Year |
|---|---|
Simvastatin Inhibits Wnt/β-Catenin Pathway in Uterine Leiomyoma.
Topics: Adolescent; Adult; beta Catenin; Cell Proliferation; Cells, Cultured; Clinical Trials, Phase II as Topic; Double-Blind Method; Down-Regulation; Female; Humans; Leiomyoma; Middle Aged; Primary Cell Culture; Randomized Controlled Trials as Topic; Simvastatin; Uterine Neoplasms; Wnt Signaling Pathway; Young Adult | 2021 |
Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF-β3 and Wnt/β-Catenin pathways.
Topics: beta Catenin; Cell Proliferation; Female; Humans; Leiomyoma; Simvastatin; Transforming Growth Factor beta3; Uterine Neoplasms | 2022 |
Simvastatin ameliorates altered mechanotransduction in uterine leiomyoma cells.
Topics: A Kinase Anchor Proteins; Collagen Type I; Cyclin D1; Extracellular Matrix; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrin beta1; Leiomyoma; Mechanotransduction, Cellular; Minor Histocompatibility Antigens; Myosin-Light-Chain Kinase; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Simvastatin; Uterine Neoplasms | 2020 |
Simvastatin and uterine fibroids: opportunity for a novel therapeutic option.
Topics: Extracellular Matrix; Humans; Leiomyoma; Simvastatin; Uterine Neoplasms | 2018 |
Simvastatin, at clinically relevant concentrations, affects human uterine leiomyoma growth and extracellular matrix production.
Topics: Apoptosis; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Extracellular Matrix; Female; Glycoproteins; Humans; Leiomyoma; Myometrium; Signal Transduction; Simvastatin; Tumor Cells, Cultured; Uterine Neoplasms; Versicans | 2018 |
Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Estrogens; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Vitro Techniques; Ki-67 Antigen; Leiomyoma; Mice; Phosphorylation; Progesterone; Progestins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Simvastatin; Uterine Neoplasms; Xenograft Model Antitumor Assays | 2015 |