simvastatin has been researched along with Pulmonary Fibrosis in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Amin, F; Etemad, L; Hashemi, M; Imenshahidi, M; Moshiri, M; Roohbakhsh, A; Salmasi, Z; Shahabadi, N; Yazdian-Robati, R | 1 |
| Bieler, M; Black, KE; Grasberger, P; Hariri, LP; Lin, Y; Medoff, BD; Nichols, R; Nicklin, P; Pantano, L; Probst, CK; Pronzati, G; Santos, DM; Seither, P; Spinney, JJ; Tager, AM; Wyatt, D | 1 |
| Choi, YH; Kang, JL; Kim, HS; Kim, MJ; Lee, YJ; Yoon, YS | 1 |
| Chai, CY; Chen, IJ; Chung, PW; Huang, HT; Kuo, MS; Liu, CP; Wu, BN | 1 |
| Arzt, M; Blumberg, FC; Lange, TJ; Lehmann, H; Nowrotek, A; Pfeifer, M; Schroll, S; Sebah, D; Wensel, R | 1 |
| Bariskaner, H; Kiyan, E; Kiyici, A; Suerdem, M; Toy, H; Tulek, B | 1 |
| Altavilla, D; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Matucci Cerinic, M; Pizzino, G; Roberts, WN; Saitta, A; Sangari, D; Squadrito, F | 1 |
| Hare, DL; Klimas, J; Kruzliak, P; Zulli, A; Zvonicek, V | 1 |
| Feng, YL; Huang, XY; Ou, XM; Wang, K; Wang, T; Wen, FQ; Xiao, J | 1 |
| Sampson, EM; Schultz, GS; Spiteri, MA; Watts, KL | 1 |
| Cottrell, E; Hoban, PR; Spiteri, MA; Watts, KL | 1 |
11 other study(ies) available for simvastatin and Pulmonary Fibrosis
| Article | Year |
|---|---|
A dose-related positive effect of inhaled simvastatin-loaded PLGA nanoparticles on paraquat-induced pulmonary fibrosis in rats.
Topics: Animals; Creatine Kinase; Humans; Lung; Nanoparticles; Paraquat; Polylactic Acid-Polyglycolic Acid Copolymer; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Saline Solution; Simvastatin | 2022 |
Screening for YAP Inhibitors Identifies Statins as Modulators of Fibrosis.
Topics: Acyl Coenzyme A; Adaptor Proteins, Signal Transducing; Animals; Biomarkers; Bleomycin; Cell Cycle Proteins; Cell Nucleus; Cytoplasm; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Mice; Phosphoproteins; Pulmonary Fibrosis; Signal Transduction; Simvastatin; Small Molecule Libraries; YAP-Signaling Proteins | 2020 |
Simvastatin treatment boosts benefits of apoptotic cell infusion in murine lung fibrosis.
Topics: Alveolar Epithelial Cells; Animals; Apoptosis; Bleomycin; Fibroblasts; Macrophages, Alveolar; Mice; Pulmonary Fibrosis; Simvastatin | 2017 |
NO-releasing xanthine KMUP-1 bonded by simvastatin attenuates bleomycin-induced lung inflammation and delayed fibrosis.
Topics: Animals; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Clarithromycin; Disease Models, Animal; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Piperidines; Pneumonia; Pulmonary Fibrosis; Signal Transduction; Simvastatin; Time Factors; Xanthines | 2014 |
Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats.
Topics: Animals; Bleomycin; Hydroxyproline; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung Compliance; Male; Motor Activity; Natriuretic Peptide, Brain; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Simvastatin | 2013 |
Effects of simvastatin on bleomycin-induced pulmonary fibrosis in female rats.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Simvastatin; Transforming Growth Factor beta1 | 2012 |
Simvastatin attenuates the development of pulmonary and cutaneous fibrosis in a murine model of systemic sclerosis.
Topics: Animals; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Immunohistochemistry; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Random Allocation; Reactive Oxygen Species; Scleroderma, Systemic; Sensitivity and Specificity; Simvastatin; Skin Diseases; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2013 |
Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study.
Topics: Animals; Anticholesteremic Agents; Diet, Atherogenic; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Lung; Pulmonary Fibrosis; Rabbits; Receptors, Angiotensin; Simvastatin | 2015 |
Simvastatin attenuates bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Simvastatin | 2008 |
Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts.
Topics: Actins; ADP Ribose Transferases; Biomarkers; Botulinum Toxins; Cell Line; Collagen; Connective Tissue Growth Factor; Fibroblasts; Gels; Gene Expression; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lung; Pulmonary Fibrosis; Recombinant Proteins; rho GTP-Binding Proteins; Simvastatin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis.
Topics: ADP Ribose Transferases; Botulinum Toxins; Cell Division; Cell Line; Connective Tissue Growth Factor; Cyclin D1; Fibroblasts; G1 Phase; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lung; Pulmonary Fibrosis; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2006 |