Page last updated: 2024-08-23

simvastatin and Pulmonary Arterial Remodeling

simvastatin has been researched along with Pulmonary Arterial Remodeling in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Cai, C; Kilari, S; Korley, JN; Misra, S; Simeon, M; Singh, A; von Recum, HA; Zhao, C; Zuckerman, ST1
Chen, Y; Dong, H; Li, Y; Wang, S; Wang, X; Wu, J; Xu, Y; Zhang, B1
Chen, YL; Guan, TW; Li, SJ; Ma, MM; Pan, L; Tang, FC; Tu, YS; Wang, HY; Yang, H; Yao, DC; Zhu, XQ1
Liu, WH; Liu, ZH; Luo, Q; Wang, Y; Xi, QY; Xu, XH; Zhang, HL; Zhao, ZH1
Bader, RR; Bruch, D; Gahtan, V; Gruessner, AC; Helkin, A; Maier, KG; Wilson, DR1
Da Costa, AM; de Medina, G; Dewachter, C; Dewachter, L; Hupkens, E; Makanga, M; Maruyama, H; Naeije, R1
Ivanovska, J; Jain, A; Jankov, RP; Kantores, C; Wong, MJ1
Barthwal, MK; Dikshit, M; Farooqui, M; Jain, M; Kanshana, JS; Khanna, V; Kumar, S; Misra, A; Singh, V1

Other Studies

8 other study(ies) available for simvastatin and Pulmonary Arterial Remodeling

ArticleYear
Periadventitial Delivery of Simvastatin-Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula.
    Journal of the American Heart Association, 2020, 12-15, Volume: 9, Issue:24

    Topics: Animals; Anticholesteremic Agents; Arteriovenous Fistula; Chemokine CCL2; Cyclodextrins; Drug Delivery Systems; Fibrosis; Graft Occlusion, Vascular; Hyperplasia; Inflammation; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Models, Animal; Neointima; Simvastatin; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Vascular Remodeling; Veins

2020
Simvastatin increases circulating endothelial progenitor cells and inhibits the formation of intracranial aneurysms in rats with diet-induced hyperhomocysteinemia.
    Neuroscience letters, 2021, 08-24, Volume: 760

    Topics: Animals; Biomarkers; Disease Models, Animal; Endothelial Progenitor Cells; Endothelium, Vascular; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Intracranial Aneurysm; Male; Rats; Rats, Sprague-Dawley; Simvastatin; Vascular Remodeling

2021
Simvastatin attenuated rat thoracic aorta remodeling by decreasing ROCK2‑mediated CyPA secretion and CD147‑ERK1/2‑cyclin pathway.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Aorta, Thoracic; Basigin; Biomarkers; Biopsy; Cyclins; Cyclophilin A; Male; MAP Kinase Signaling System; Rats; rho-Associated Kinases; Signal Transduction; Simvastatin; Vascular Remodeling

2017
Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:3

    Topics: Animals; Blood Pressure; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Mevalonic Acid; Monocrotaline; Polyisoprenyl Phosphates; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Vascular Remodeling

2018
Intraluminal Delivery of Simvastatin Attenuates Intimal Hyperplasia After Arterial Injury.
    Vascular and endovascular surgery, 2019, Volume: 53, Issue:5

    Topics: Administration, Oral; Animals; Caproates; Carotid Artery Injuries; Carotid Artery, Common; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Hyaluronic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Micelles; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Polymers; Rats, Sprague-Dawley; Sialic Acids; Simvastatin; Tunica Intima; Vascular Remodeling

2019
Prevention of pulmonary hypoplasia and pulmonary vascular remodeling by antenatal simvastatin treatment in nitrofen-induced congenital diaphragmatic hernia.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Apr-01, Volume: 308, Issue:7

    Topics: Animals; Apoptosis; Bone Morphogenetic Protein Receptors, Type II; Female; Hernias, Diaphragmatic, Congenital; Lung; Lung Diseases; Phenyl Ethers; Pregnancy; Rats, Sprague-Dawley; Simvastatin; Vascular Remodeling

2015
Simvastatin prevents and reverses chronic pulmonary hypertension in newborn rats via pleiotropic inhibition of RhoA signaling.
    American journal of physiology. Lung cellular and molecular physiology, 2016, 11-01, Volume: 311, Issue:5

    Topics: Animals; Animals, Newborn; Biosynthetic Pathways; Blood Pressure; Cholesterol; Chronic Disease; Female; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Male; Myelin Sheath; Nitric Oxide Synthase Type III; Organ Size; Physical Conditioning, Animal; Polyisoprenyl Phosphates; Pulmonary Artery; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Sesquiterpenes; Signal Transduction; Simvastatin; Vascular Remodeling

2016
Progression and Characterization of the Accelerated Atherosclerosis in Iliac Artery of New Zealand White Rabbits: Effect of Simvastatin.
    Journal of cardiovascular pharmacology, 2017, Volume: 69, Issue:5

    Topics: Angioplasty, Balloon; Animals; Atherosclerosis; Biomarkers; Diet, High-Fat; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Extracellular Matrix; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iliac Artery; Inflammation Mediators; Lipids; Macrophages; Male; Plaque, Atherosclerotic; Rabbits; Simvastatin; Time Factors; Vascular Remodeling; Vasoconstriction; Vasodilation

2017