simvastatin has been researched along with Osteoarthritis, Knee in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karasawa, R; Yudoh, K | 1 |
| Aktas, E; Gocun, PU; Sener, E | 1 |
2 other study(ies) available for simvastatin and Osteoarthritis, Knee
| Article | Year |
|---|---|
Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA).
Topics: Aged; Animals; beta-Galactosidase; Cartilage, Articular; Cell Proliferation; Cells, Cultured; Cellular Senescence; Chondrocytes; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Mice; Osteoarthritis, Knee; Simvastatin; Time Factors | 2010 |
Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3.
Topics: Animals; Anti-Inflammatory Agents; Chondrocytes; Disease Models, Animal; Disease Progression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Male; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Osteoarthritis, Knee; Rats; Rats, Wistar; Simvastatin; Stress, Mechanical | 2011 |