simvastatin has been researched along with Nerve Degeneration in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdelsalam, RM; Ahmed, LA; Amin, HA; Darwish, HA | 1 |
| Chopp, M; Han, Y; Karki, K; Knight, RA; Ledbetter, KA; Seyfried, DM; Yang, D; Zhang, J | 1 |
| Deng, C; Huang, XF; Wang, Q; Wu, A; Xiong, Z; Xu, Y; Yan, J; Yang, Y; Yang, YG; Yenari, MA; Ying, W; Zhang, L; Zhu, C | 1 |
| Bodmer, D; Brand, Y; Chavez, E; Levano, S; Listyo, A; Pak, K; Radojevic, V; Ryan, AF; Setz, C; Sung, M | 1 |
| Balduini, W; Carloni, S; Cimino, M; De Simoni, MG; Mazzoni, E; Perego, C; Scopa, C | 1 |
| Choi, IY; Kim, HS; Kim, WK; Lee, JC; Lee, YH; Lim, JH; Oh, YK; Park, JS | 1 |
| Eckert, GP; Franke, C; Igbavboa, U; Johnson-Anuna, LN; Müller, WE; Wood, WG | 1 |
| Guyton, JR; Laskowitz, DT; Lynch, JR; Mace, B; Song, P; Wang, H; Warner, DS; Yang, HJ; Yates, RB | 1 |
| Chen, J; Chopp, M; Goussev, A; Jiang, H; Li, Y; Lu, C; Lu, D; Mahmood, A; Qu, C; Schallert, T | 1 |
| Argüelles, S; Cano, J; de Pablos, RM; Delgado-Cortés, MJ; Hernández-Romero, MC; Herrera, AJ; Machado, A; Santiago, M; Villarán, RF | 1 |
10 other study(ies) available for simvastatin and Nerve Degeneration
| Article | Year |
|---|---|
Role of Rho Kinase Inhibition in the Protective Effect of Fasudil and Simvastatin Against 3-Nitropropionic Acid-Induced Striatal Neurodegeneration and Mitochondrial Dysfunction in Rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; bcl-2-Associated X Protein; Behavior, Animal; Body Weight; Caspase 3; Corpus Striatum; Male; Membrane Potential, Mitochondrial; Mitochondria; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitro Compounds; Organ Size; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Propionates; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Wistar; rho-Associated Kinases; Simvastatin; Succinate Dehydrogenase; Tumor Necrosis Factor-alpha | 2016 |
Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage.
Topics: Animals; Apoptosis; Atorvastatin; Biomarkers; Brain; Brain Infarction; Bromodeoxyuridine; Cerebral Hemorrhage; Cytoprotection; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microtubule-Associated Proteins; Nerve Degeneration; Neurogenesis; Neuronal Plasticity; Neuropeptides; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Regeneration; Simvastatin; Treatment Outcome | 2009 |
Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.
Topics: Animals; Anti-Inflammatory Agents; Anxiety; Apoptosis; Autoradiography; Cell Survival; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Glutamic Acid; Immunohistochemistry; L-Lactate Dehydrogenase; Male; Matrix Metalloproteinase 9; Nerve Degeneration; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Simvastatin; Substantia Nigra; Tritium; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2011 |
Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Transgenic; Nerve Degeneration; Neuroprotective Agents; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Simvastatin | 2011 |
Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat.
Topics: Animals; Animals, Newborn; Apoptosis; Biomarkers; Calpain; Caspase 1; Caspase 3; Caspases; Cytochromes c; Enzyme Activation; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Ischemia, Brain; Intercellular Adhesion Molecule-1; Interleukin-1; Nerve Degeneration; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Simvastatin | 2006 |
Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal.
Topics: Aldehydes; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cytoprotection; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Ischemia, Brain; Lipid Peroxidation; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Simvastatin | 2006 |
Simvastatin protects neurons from cytotoxicity by up-regulating Bcl-2 mRNA and protein.
Topics: Animals; Caspase 3; Cell Death; Cell Line, Tumor; Cytoprotection; Cytotoxins; Humans; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Simvastatin; Thionucleotides; Up-Regulation | 2007 |
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Brain Edema; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Chemotaxis, Leukocyte; Cognition Disorders; Cytokines; Disease Models, Animal; Encephalitis; Endothelial Cells; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Pyrroles; Recovery of Function; RNA, Messenger; Simvastatin; Treatment Outcome | 2007 |
Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury.
Topics: Animals; Atorvastatin; Brain Injuries; Cell Proliferation; Dentate Gyrus; Dose-Response Relationship, Drug; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Maze Learning; Memory Disorders; Neovascularization, Physiologic; Nerve Degeneration; Nerve Regeneration; Neuronal Plasticity; Neurons; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Recovery of Function; Simvastatin; Stem Cells; Treatment Outcome | 2007 |
Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide.
Topics: Animals; Anticholesteremic Agents; Arachidonic Acids; Dopamine; Drug Interactions; Gene Expression Regulation; Inflammation; Male; Nerve Degeneration; Nerve Tissue Proteins; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Simvastatin; Substantia Nigra; Tumor Necrosis Factor-alpha | 2008 |