Page last updated: 2024-08-23

simvastatin and Myalgia

simvastatin has been researched along with Myalgia in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's16 (88.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Goel, A; Lavezo, J; Podboy, A; Wong, K1
Álvarez, D; Cartier, M; Marino, M; Míguez, C; Muñoz, AE; Pollarsky, F; Romero, G; Salgado, P; Vázquez, H1
Adriano, E; Balestrino, M1
Chrøis, KM; Dela, F; Dohlmann, TL; Helge, JW; Kuhlman, AB; Larsen, S; Morville, T1
Christopher-Stine, L; Isackson, PJ; Kitzmiller, JP; Luzum, JA; Ma, C; Nguyen, LM; Ochs-Balcom, HM; Peltier, W; Tarnopolsky, M; Vladutiu, GD; Weisman, M; Wortmann, RL1
Dela, F; Dohlmann, TL; Helge, JW; Kriegbaum, M; Kuhlman, AB; Larsen, S; Morville, T; Sahl, RE1
Snipelisky, D; Stancampiano, F1
Heckman, K; Kellick, K; Mergenhagen, K; Ott, M; Rubin, LM1
Almeida, S; Ferreira, ME; Fiegenbaum, M; Hutz, MH; Lima, LO; Pires, RC; Smiderle, L; Van der Sand, CR; Van der Sand, LC1
Lorson, L; Taylor, BA; Thompson, PD; White, CM1
Feingold, KR1
Adamkova, V; Ceska, R; Hruba, P; Hubacek, JA; Vrablik, M1
Adámková, V; Češka, R; Dlouhá, D; Hrubá, P; Hubáček, JA; Viklický, O; Vrablík, M; Zlatohlavek, L1
Foerster, J; Schetz, D; Sein Anand, J1
Panza, G; Taylor, BA; Thompson, PD1
Kormos, W1
Adams-Huet, B; Ahmad, Z; Khine, H; Yuet, WC1
Aggarwal, AN; Badal, D; Bhansali, A; Bhat, OM; Rastogi, A; Singla, M1

Trials

5 trial(s) available for simvastatin and Myalgia

ArticleYear
Safety of Chronic Simvastatin Treatment in Patients with Decompensated Cirrhosis: Many Adverse Events but No Liver Injury.
    Digestive diseases and sciences, 2021, Volume: 66, Issue:9

    Topics: Argentina; Cardiovascular Diseases; Disease Progression; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Diseases; Headache; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Male; Middle Aged; Myalgia; Outcome and Process Assessment, Health Care; Risk Assessment; Severity of Illness Index; Simvastatin

2021
Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study.
    The Journal of clinical endocrinology and metabolism, 2019, 07-01, Volume: 104, Issue:7

    Topics: Adult; Aged; Cardiovascular Diseases; Cross-Sectional Studies; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Mitochondria; Muscle, Skeletal; Myalgia; Reactive Oxygen Species; Simvastatin; Ubiquinone

2019
A randomized trial of coenzyme Q10 in patients with confirmed statin myopathy.
    Atherosclerosis, 2015, Volume: 238, Issue:2

    Topics: Aged; Connecticut; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Muscle Strength; Muscle, Skeletal; Myalgia; Oxygen Consumption; Pain Measurement; Severity of Illness Index; Simvastatin; Surveys and Questionnaires; Time Factors; Treatment Outcome; Ubiquinone

2015
Increased creatine kinase with statin treatment may identify statin-associated muscle symptoms.
    International journal of cardiology, 2016, Apr-15, Volume: 209

    Topics: Biomarkers; Creatine Kinase; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myalgia; Simvastatin; Treatment Outcome

2016
Vitamin D supplementation improves simvastatin-mediated decline in exercise performance: A randomized double-blind placebo-controlled study.
    Journal of diabetes, 2017, Volume: 9, Issue:12

    Topics: Adult; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Exercise; Exercise Therapy; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Myalgia; Oxygen Consumption; Simvastatin; Vitamin D; Vitamins

2017

Other Studies

13 other study(ies) available for simvastatin and Myalgia

ArticleYear
Dead Meat: Glecaprevir/Pibrentasvir-Induced Statin Myonecrosis.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:2

    Topics: Antiviral Agents; Benzimidazoles; Biopsy; Coronary Artery Disease; Drug Combinations; Drug Interactions; Hepatitis C, Chronic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Cirrhosis; Male; Middle Aged; Myalgia; Pyrrolidines; Quinoxalines; Rhabdomyolysis; Simvastatin; Sulfonamides

2020
Statin-induced myopathy prevented by creatine administration.
    BMJ case reports, 2018, Aug-27, Volume: 2018

    Topics: Aged; Amaurosis Fugax; Anticholesteremic Agents; Carotid Stenosis; Cholesterol, LDL; Creatine; Drug Therapy, Combination; Ezetimibe; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myalgia; Pyrimidines; Simvastatin; Treatment Outcome

2018
Clinical features related to statin-associated muscle symptoms.
    Muscle & nerve, 2019, Volume: 59, Issue:5

    Topics: Aged; Atorvastatin; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Logistic Models; Lovastatin; Male; Medical History Taking; Middle Aged; Muscle Weakness; Muscular Diseases; Myalgia; Obesity; Odds Ratio; Pravastatin; Retrospective Studies; Rhabdomyolysis; Risk Factors; Rosuvastatin Calcium; Simvastatin; Smoking; White People

2019
Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study.
    Medicine and science in sports and exercise, 2019, Volume: 51, Issue:7

    Topics: Cardiovascular Diseases; Cross-Sectional Studies; Exercise Tolerance; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Male; Middle Aged; Muscle Strength; Myalgia; Myosin Heavy Chains; Primary Prevention; Simvastatin

2019
An 85-year-old with muscle pain.
    Cleveland Clinic journal of medicine, 2014, Volume: 81, Issue:1

    Topics: Aged, 80 and over; Drug Substitution; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Male; Myalgia; Simvastatin; Withholding Treatment

2014
Low vitamin D as a risk factor for the development of myalgia in patients taking high-dose simvastatin: a retrospective review.
    Clinical therapeutics, 2014, Volume: 36, Issue:5

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Humans; Logistic Models; Male; Medical Records; Middle Aged; Muscular Diseases; Myalgia; Retrospective Studies; Rhabdomyolysis; Risk Factors; Simvastatin; Vitamin D; Vitamin D Deficiency; Young Adult

2014
Evaluation of sexual dimorphism in the efficacy and safety of simvastatin/atorvastatin therapy in a southern Brazilian cohort.
    Arquivos brasileiros de cardiologia, 2014, Volume: 103, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Brazil; Cholesterol; Creatine Kinase; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Myalgia; Prospective Studies; Pyrroles; Sex Factors; Simvastatin

2014
Statin myopathy: a problem looking for a solution.
    Atherosclerosis, 2015, Volume: 239, Issue:1

    Topics: Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscle, Skeletal; Myalgia; Simvastatin; Ubiquinone

2015
Association between polymorphism within the RYR2 receptor and development of statin-associated myalgia/myopathy in the Czech population.
    European journal of internal medicine, 2015, Volume: 26, Issue:5

    Topics: Aged; Atorvastatin; Case-Control Studies; Czech Republic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myalgia; Pilot Projects; Polymorphism, Genetic; Ryanodine Receptor Calcium Release Channel; Simvastatin; White People

2015
SLCO1B1 polymorphism is not associated with risk of statin-induced myalgia/myopathy in a Czech population.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, May-20, Volume: 21

    Topics: Aged; Atorvastatin; Czech Republic; Diabetes Mellitus; Dose-Response Relationship, Drug; Dyslipidemias; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Models, Genetic; Muscular Diseases; Myalgia; Obesity; Organic Anion Transporters; Polymorphism, Single Nucleotide; Simvastatin; Smoking

2015
[Drug interaction in 63-year-old male sportsman--a case report].
    Przeglad lekarski, 2015, Volume: 72, Issue:9

    Topics: Amlodipine; Confusion; Dizziness; Drug Interactions; Exercise; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Myalgia; Simvastatin

2015
On call. I am taking simvastatin for high cholesterol. Should I take coenzyme Q ₁₀ to prevent muscle pain?
    Harvard men's health watch, 2013, Volume: 17, Issue:9

    Topics: Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Myalgia; Simvastatin; Ubiquinone

2013
Statin-associated muscle symptoms and SLCO1B1 rs4149056 genotype in patients with familial hypercholesterolemia.
    American heart journal, 2016, Volume: 179

    Topics: Age Factors; Body Mass Index; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Hypertension; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Myalgia; Odds Ratio; Pravastatin; Rosuvastatin Calcium; Simvastatin

2016