simvastatin has been researched along with Muscle Contraction in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 14 (66.67) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Fenning, AS; Irwin, JC; Vella, RK | 1 |
| El-Adeeb, N; Elmasry, A; Ghalwash, M | 1 |
| Domokos, D; Ducza, E; Gáspár, R | 1 |
| Bal, IB; Onur, R; Sara, Y; Severcan, F; Simsek Ozek, N | 1 |
| Bae, ON; Bae, YM; Chung, JH; Kang, S; Kim, K; Lee, MY; Lim, KM; Noh, JY; Woo, HH | 1 |
| Bedi, A; Davis, ME; Gumucio, JP; Harning, JA; Korn, MA; Mendias, CL; Saripalli, AL | 1 |
| Hamel, E; Tong, XK | 1 |
| Constantin-Teodosiu, D; Greenhaff, PL; Mallinson, JE; Marimuthu, K; Murton, A; Rennie, MJ; Selby, A; Smith, K | 1 |
| Bae, ON; Chung, JH; Jung, Y; Kang, S; Kim, K; Lim, KM; Noh, JY | 1 |
| Call, JA; Jenkins, NT; McCully, KK; Nichenko, AS; Shill, DD; Southern, WM; Spencer, CC | 1 |
| Belousova, ES; Mikashinovich, ZI; Sarkisyan, OG | 1 |
| Gaggioli, C; Hooper, S; Sahai, E | 1 |
| Rattan, S | 1 |
| Campolongo, P; Fanelli, F; Jozwiak, A; Linari, M; Melli, L; Moreno, S; Pallottini, V; Pucillo, LP; Segatto, M; Swiezewska, E; Trapani, L; Trezza, V | 1 |
| Armeson, KE; Ellett, J; Hughes, FM; McKeithan, P; Purves, JT | 1 |
| Baker, SK; Tarnopolsky, MA | 1 |
| Ito, S; Ito, Y; Kondo, M; Kume, H; Naruse, K; Oguma, T; Shimokata, K; Suki, B | 1 |
| Abd el Latif, HA; Abd el-Fattah, AA; al-Zuhair, H | 1 |
| Camerino, C; Conte Camerino, D; De Luca, A; Liantonio, A; Pierno, S | 1 |
| Frohlich, BH; Gregg, RE; Tesfamariam, B | 1 |
| Altieri, PI; Crespo, MJ; Escobales, N; Furilla, RA | 1 |
21 other study(ies) available for simvastatin and Muscle Contraction
| Article | Year |
|---|---|
Statins with different lipophilic indices exert distinct effects on skeletal, cardiac and vascular smooth muscle.
Topics: Animals; Female; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microelectrodes; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth, Vascular; Myocardium; Pravastatin; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Transcriptome; Ventricular Function, Left | 2020 |
Effect of L-carnitine on the skeletal muscle contractility in simvastatin-induced myopathy in rats.
Topics: Animals; Carnitine; Cholesterol; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Contraction; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; Rats; Rats, Wistar; Simvastatin | 2018 |
RhoA and Rho-kinase inhibitors modulate cervical resistance: The possible role of RhoA/Rho-kinase signalling pathway in cervical ripening and contractility.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cervical Ripening; Cervix Uteri; Female; In Vitro Techniques; Muscle Contraction; Pregnancy; Pyridines; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Simvastatin | 2019 |
Structural and functional characterization of simvastatin-induced myotoxicity in different skeletal muscles.
Topics: Animals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ion Channels; Male; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Muscular Diseases; Rats; Rats, Wistar; Simvastatin; Spectroscopy, Fourier Transform Infrared | 2014 |
Dysfunction of vascular smooth muscle and vascular remodeling by simvastatin.
Topics: Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Simvastatin; Time Factors; Vasoconstriction | 2014 |
Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear.
Topics: Acetyl-CoA C-Acetyltransferase; Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; CCAAT-Binding Factor; Chronic Disease; Extracellular Matrix Proteins; Fibrosis; Gene Expression; Inflammation; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Weakness; Myosin Heavy Chains; PPAR gamma; Rats; Rats, Sprague-Dawley; Regeneration; Rotator Cuff; Rotator Cuff Injuries; Rupture; Shoulder Pain; Simvastatin | 2015 |
Simvastatin restored vascular reactivity, endothelial function and reduced string vessel pathology in a mouse model of cerebrovascular disease.
Topics: Animals; Blotting, Western; Brain; Cerebral Arteries; Cerebrovascular Disorders; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Muscle, Smooth, Vascular; Neuroprotective Agents; Rats; Simvastatin | 2015 |
Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Case-Control Studies; Humans; Insulin Resistance; Male; Muscle Contraction; Muscle Proteins; Muscle Strength; Muscle Weakness; Reaction Time; RNA, Messenger; Simvastatin | 2015 |
Simvastatin induces the apoptosis of normal vascular smooth muscle through the disruption of actin integrity via the impairment of RhoA/Rac-1 activity.
Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Apoptosis; cdc42 GTP-Binding Protein; Cells, Cultured; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Membrane Potential, Mitochondrial; Mitochondria, Muscle; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Simvastatin; Vasoconstriction | 2016 |
Skeletal muscle metabolic adaptations to endurance exercise training are attainable in mice with simvastatin treatment.
Topics: Adaptation, Physiological; Animals; Anticholesteremic Agents; Autophagy; Autophagy-Related Proteins; Male; Mice; Mice, Inbred C57BL; Mitochondria; Motor Activity; Muscle Contraction; Muscle, Skeletal; Physical Conditioning, Animal; Running; Simvastatin | 2017 |
Impairment of Energy-Dependent Processes in the Muscle Tissue as a Pathogenetic Mechanism of Statin-Induced Myopathy.
Topics: Animals; Animals, Outbred Strains; Anticholesteremic Agents; Electron Transport; Electron Transport Complex IV; Male; Mitochondria; Muscle Contraction; Muscle, Skeletal; Muscular Diseases; Oxidative Phosphorylation; Rats; Simvastatin; Superoxide Dismutase | 2017 |
A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion.
Topics: Actomyosin; Carcinoma, Squamous Cell; Extracellular Matrix; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrin alpha5; Lovastatin; Muscle Contraction; Neoplasm Invasiveness; rab GTP-Binding Proteins; Simvastatin | 2010 |
3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylation.
Topics: Animals; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Contraction; Muscle, Smooth; Prenylation; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Simvastatin | 2010 |
Effects of myosin heavy chain (MHC) plasticity induced by HMGCoA-reductase inhibition on skeletal muscle functions.
Topics: Animals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Motor Activity; Muscle Contraction; Muscle, Skeletal; Myosin Heavy Chains; Protein Isoforms; Rats; Rats, Wistar; Simvastatin | 2011 |
Simvastatin suppresses cyclophosphamide-induced changes in urodynamics and bladder inflammation.
Topics: Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cystitis; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Contraction; Pressure; Rats; Rats, Sprague-Dawley; Simvastatin; Urinary Bladder; Urination; Urine; Urodynamics | 2013 |
Sporadic rippling muscle disease unmasked by simvastatin.
Topics: Anticholesteremic Agents; Calcium; Caveolin 3; Dysferlin; Homeostasis; Humans; Hypercholesterolemia; Male; Membrane Proteins; Middle Aged; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Muscular Diseases; Myasthenia Gravis; Simvastatin | 2006 |
Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cations; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gadolinium; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Ion Channels; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrobenzenes; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; rho-Associated Kinases; Simvastatin; Stress, Mechanical; Sulfonamides; Trachea | 2006 |
Efficacy of simvastatin and pumpkin-seed oil in the management of dietary-induced hypercholesterolemia.
Topics: Adrenergic alpha-Agonists; Animals; Anticholesteremic Agents; Cholesterol, Dietary; Diet; Dose-Response Relationship, Drug; Hypercholesterolemia; In Vitro Techniques; Lipids; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Plant Oils; Rabbits; Simvastatin | 1997 |
Effects of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle.
Topics: Animals; Anticholesteremic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Pravastatin; Rats; Rats, Wistar; Simvastatin | 1999 |
Differential effects of pravastatin, simvastatin, and atorvastatin on Ca2+ release and vascular reactivity.
Topics: Animals; Anticholesteremic Agents; Aorta; Atorvastatin; Calcium; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mevalonic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley; Simvastatin; Vasoconstrictor Agents | 1999 |
Inhibition of smooth muscle cell calcium mobilization and aortic ring contraction by lactone vastatins.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aorta, Thoracic; Calcium; Collagen Type VIII; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Lovastatin; Male; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Vasoconstrictor Agents | 1996 |