simvastatin has been researched along with Malignant Mesothelioma in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cabeza, JZ; Cain, K; Chernova, T; Craxton, A; Grosso, S; MacFarlane, M; Nakas, A; Self, EL; Sun, XM; Tenor, AR; Willis, AE | 1 |
| Cha, BK; Hwang, KE; Hwang, YR; Jeong, ET; Kim, BR; Kim, HR; Kim, YS; Kwon, SJ; Park, DS; Yoon, KH | 1 |
| Cha, BK; Hwang, KE; Jeong, ET; Jung, JW; Kim, HR; Kim, YS; Kwon, SJ; Oh, SH; Park, DS; Yoon, KH | 1 |
| Hida, T; Horio, Y; Murakami-Tonami, Y; Osada, H; Sekido, Y; Tanaka, K | 1 |
4 other study(ies) available for simvastatin and Malignant Mesothelioma
| Article | Year |
|---|---|
Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells.
Topics: Cancer-Associated Fibroblasts; Carcinogenesis; Cell Line, Tumor; Extracellular Vesicles; Humans; Mesothelioma; Mesothelioma, Malignant; Simvastatin; Tumor Microenvironment; YAP-Signaling Proteins | 2022 |
Enhanced apoptosis by pemetrexed and simvastatin in malignant mesothelioma and lung cancer cells by reactive oxygen species-dependent mitochondrial dysfunction and Bim induction.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Drug Synergism; Gene Expression Regulation, Neoplastic; Glutamates; Guanine; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Membrane Proteins; Mesothelioma; Mesothelioma, Malignant; Pemetrexed; Proto-Oncogene Proteins; Reactive Oxygen Species; Simvastatin | 2014 |
Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Autophagy-Related Protein 5; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Macrolides; Mesothelioma; Mesothelioma, Malignant; Mice, Nude; Microtubule-Associated Proteins; Pemetrexed; Pepstatins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; Simvastatin; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Gene Expression Regulation, Neoplastic; Hippo Signaling Pathway; Humans; Hyaluronan Receptors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mevalonic Acid; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurofibromin 2; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA Interference; Signal Transduction; Simvastatin; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; YAP-Signaling Proteins | 2017 |