Page last updated: 2024-08-23

simvastatin and Lymphangiomyomatosis

simvastatin has been researched along with Lymphangiomyomatosis in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Courtwright, AM; Dorgan, D; Fleck, V; Kotloff, R; Kreider, M; Krymskaya, VP; McCormack, FX1
Atochina-Vasserman, EN; Goncharov, DA; James, ML; Krymskaya, VP; Milavec, M; Volgina, AV1
Jones, AM; Julien-Williams, PA; Moss, J; Stylianou, M; Taveira-DaSilva, AM1
Albelda, SM; Colby, TV; Ducka, B; Fehrenbach, M; Goncharov, DA; Goncharova, EA; Haczku, A; Hino, O; Khavin, I; Krymskaya, VP; Merrilees, MJ1

Trials

1 trial(s) available for simvastatin and Lymphangiomyomatosis

ArticleYear
A phase II clinical trial of the Safety Of Simvastatin (SOS) in patients with pulmonary lymphangioleiomyomatosis and with tuberous sclerosis complex.
    Respiratory medicine, 2020, Volume: 163

    Topics: Drug Therapy, Combination; Everolimus; Female; Forced Expiratory Volume; Humans; Lymphangioleiomyomatosis; Male; Safety; Simvastatin; Sirolimus; Treatment Outcome; Tuberous Sclerosis

2020

Other Studies

3 other study(ies) available for simvastatin and Lymphangiomyomatosis

ArticleYear
Statins in lymphangioleiomyomatosis. Simvastatin and atorvastatin induce differential effects on tuberous sclerosis complex 2-null cell growth and signaling.
    American journal of respiratory cell and molecular biology, 2013, Volume: 49, Issue:5

    Topics: Animals; Atorvastatin; Caspase 3; Cell Line; Cell Proliferation; Cell Shape; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Heptanoic Acids; Humans; Lymphangioleiomyomatosis; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; Simvastatin; Sirolimus; TOR Serine-Threonine Kinases; Transfection; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2013
Retrospective review of combined sirolimus and simvastatin therapy in lymphangioleiomyomatosis.
    Chest, 2015, Volume: 147, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Lung Neoplasms; Lymphangioleiomyomatosis; Male; Middle Aged; Respiratory Function Tests; Retrospective Studies; Simvastatin; Sirolimus; Treatment Outcome; Young Adult

2015
Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM).
    Science translational medicine, 2012, Oct-03, Volume: 4, Issue:154

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; In Vitro Techniques; Lung Neoplasms; Lymphangioleiomyomatosis; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Mice; Mice, Nude; Simvastatin; Sirolimus; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor D

2012