simvastatin has been researched along with Liver Dysfunction in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Arnaboldi, F; Bitto, N; Colombo, M; Denti, L; Dondossola, D; Gagliano, N; La Mura, V; Latini, R; Liguori, E; Peyvandi, F; Procacci, P; Ristagno, G; Salerno, F; Sartori, P; Tripodi, A | 1 |
| Arnon, R; Cork, E; Dolinger, M; Ferguson, E; Iverson, A; Prasun, P; Ward, SC | 1 |
| Al-Dosari, MS | 1 |
| Ekici, MF; Genc, O; Kocak, A; Kocak, C; Kocak, FE; Kucuk, A; Ozyigit, F; Tosun, M; Yaylak, F | 1 |
| Dibazar, F; Ghandiha, A; Hajipour, B; Hemmati, MR; Hosseinian, MM | 1 |
| Dold, S; Jeppsson, B; Laschke, MW; Lavasani, S; Menger, MD; Thorlacius, H | 1 |
| Helmy, MM | 1 |
| Alican, I; Ercan, F; Gedik, N; Işeri, S; Yüksel, M | 1 |
| Alsheikh-Ali, AA; Karas, RH | 1 |
| Abraldes, JG; Bosch, J; García-Calderó, H; García-Pagán, JC; Graupera, M; Rodríguez-Vilarrupla, A; Zafra, C | 1 |
| Alsheikh-Ali, AA; Han, H; Karas, RH; Maddukuri, PV | 1 |
| Lee, TH | 1 |
1 review(s) available for simvastatin and Liver Dysfunction
| Article | Year |
|---|---|
Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.
Topics: Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Diseases; Lovastatin; Neoplasms; Pravastatin; Rhabdomyolysis; Simvastatin | 2007 |
11 other study(ies) available for simvastatin and Liver Dysfunction
| Article | Year |
|---|---|
Simvastatin Prevents Liver Microthrombosis and Sepsis Induced Coagulopathy in a Rat Model of Endotoxemia.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Endotoxemia; Fibrin; Hemostatics; Lipopolysaccharides; Liver Diseases; Male; Necrosis; Rats; Rats, Wistar; Sepsis; Simvastatin; Thrombosis; von Willebrand Factor | 2022 |
Lathosterolosis: An Extremely Rare Inherited Condition Associated With Progressive Liver Disease.
Topics: Abnormalities, Multiple; Child; Diagnosis, Differential; Disease Progression; Female; Genetic Predisposition to Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Diseases; Oxidoreductases Acting on CH-CH Group Donors; Simvastatin; Steroid Metabolism, Inborn Errors | 2019 |
Red cabbage (Brassica oleracea L.) mediates redox-sensitive amelioration of dyslipidemia and hepatic injury induced by exogenous cholesterol administration.
Topics: Animals; Brassica; Cell Proliferation; Cell Survival; Cholesterol, Dietary; Cytoprotection; Dose-Response Relationship, Drug; Dyslipidemias; Free Radical Scavengers; Hep G2 Cells; Hepatocytes; Humans; Liver Diseases; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Simvastatin | 2014 |
Protective effects of simvastatin administered in the experimental hepatic ischemia-reperfusion injury rat model.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Diseases; Male; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Simvastatin | 2015 |
Simvastatin decreases hepatic ischaemia/reperfusion-induced liver and lung injury in rats.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Liver Diseases; Lung Injury; Rats; Reperfusion Injury; Simvastatin; Tumor Necrosis Factor-alpha | 2008 |
Simvastatin protects against cholestasis-induced liver injury.
Topics: Animals; Chemokines, CXC; Cholestasis; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocyte Rolling; Liver; Liver Diseases; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Peroxidase; Simvastatin | 2009 |
Potential hepato-protective effect of α-tocopherol or simvastatin in aged rats.
Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Antioxidants; Catalase; Lipids; Liver; Liver Diseases; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Simvastatin; Thiobarbituric Acid Reactive Substances | 2012 |
Simvastatin attenuates cisplatin-induced kidney and liver damage in rats.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Bilirubin; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Cisplatin; Creatinine; Female; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; L-Lactate Dehydrogenase; Liver Diseases; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley; Serum Albumin; Simvastatin | 2007 |
Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system).
Topics: Adverse Drug Reaction Reporting Systems; Atorvastatin; Chemical and Drug Induced Liver Injury; Drug Prescriptions; Drug Therapy, Combination; Dyslipidemias; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver Diseases; Lovastatin; Niacin; Pravastatin; Prevalence; Pyrroles; Retrospective Studies; Rhabdomyolysis; Risk Factors; Simvastatin; United States; United States Food and Drug Administration | 2007 |
Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats.
Topics: Animals; Anticholesteremic Agents; Carbon Tetrachloride; Cyclic GMP; Liver; Liver Cirrhosis; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Perfusion; Phosphorylation; Rats; Rats, Wistar; Simvastatin | 2007 |
I take Zocor for high cholesterol. My doctor checks my lipid levels every six months and they have been pretty good for a few years now. But he also checks my liver-function tests, because liver damage is one of the side effects of this drug. How worried
Topics: Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Liver Function Tests; Simvastatin | 1998 |