Page last updated: 2024-08-23

simvastatin and Liver Dysfunction

simvastatin has been researched along with Liver Dysfunction in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's6 (50.00)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Arnaboldi, F; Bitto, N; Colombo, M; Denti, L; Dondossola, D; Gagliano, N; La Mura, V; Latini, R; Liguori, E; Peyvandi, F; Procacci, P; Ristagno, G; Salerno, F; Sartori, P; Tripodi, A1
Arnon, R; Cork, E; Dolinger, M; Ferguson, E; Iverson, A; Prasun, P; Ward, SC1
Al-Dosari, MS1
Ekici, MF; Genc, O; Kocak, A; Kocak, C; Kocak, FE; Kucuk, A; Ozyigit, F; Tosun, M; Yaylak, F1
Dibazar, F; Ghandiha, A; Hajipour, B; Hemmati, MR; Hosseinian, MM1
Dold, S; Jeppsson, B; Laschke, MW; Lavasani, S; Menger, MD; Thorlacius, H1
Helmy, MM1
Alican, I; Ercan, F; Gedik, N; Işeri, S; Yüksel, M1
Alsheikh-Ali, AA; Karas, RH1
Abraldes, JG; Bosch, J; García-Calderó, H; García-Pagán, JC; Graupera, M; Rodríguez-Vilarrupla, A; Zafra, C1
Alsheikh-Ali, AA; Han, H; Karas, RH; Maddukuri, PV1
Lee, TH1

Reviews

1 review(s) available for simvastatin and Liver Dysfunction

ArticleYear
Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.
    Journal of the American College of Cardiology, 2007, Jul-31, Volume: 50, Issue:5

    Topics: Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Diseases; Lovastatin; Neoplasms; Pravastatin; Rhabdomyolysis; Simvastatin

2007

Other Studies

11 other study(ies) available for simvastatin and Liver Dysfunction

ArticleYear
Simvastatin Prevents Liver Microthrombosis and Sepsis Induced Coagulopathy in a Rat Model of Endotoxemia.
    Cells, 2022, 03-29, Volume: 11, Issue:7

    Topics: Animals; Disease Models, Animal; Endothelial Cells; Endotoxemia; Fibrin; Hemostatics; Lipopolysaccharides; Liver Diseases; Male; Necrosis; Rats; Rats, Wistar; Sepsis; Simvastatin; Thrombosis; von Willebrand Factor

2022
Lathosterolosis: An Extremely Rare Inherited Condition Associated With Progressive Liver Disease.
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:5

    Topics: Abnormalities, Multiple; Child; Diagnosis, Differential; Disease Progression; Female; Genetic Predisposition to Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Diseases; Oxidoreductases Acting on CH-CH Group Donors; Simvastatin; Steroid Metabolism, Inborn Errors

2019
Red cabbage (Brassica oleracea L.) mediates redox-sensitive amelioration of dyslipidemia and hepatic injury induced by exogenous cholesterol administration.
    The American journal of Chinese medicine, 2014, Volume: 42, Issue:1

    Topics: Animals; Brassica; Cell Proliferation; Cell Survival; Cholesterol, Dietary; Cytoprotection; Dose-Response Relationship, Drug; Dyslipidemias; Free Radical Scavengers; Hep G2 Cells; Hepatocytes; Humans; Liver Diseases; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Simvastatin

2014
Protective effects of simvastatin administered in the experimental hepatic ischemia-reperfusion injury rat model.
    The Journal of surgical research, 2015, Volume: 199, Issue:2

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Diseases; Male; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Simvastatin

2015
Simvastatin decreases hepatic ischaemia/reperfusion-induced liver and lung injury in rats.
    Folia morphologica, 2008, Volume: 67, Issue:4

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Liver Diseases; Lung Injury; Rats; Reperfusion Injury; Simvastatin; Tumor Necrosis Factor-alpha

2008
Simvastatin protects against cholestasis-induced liver injury.
    British journal of pharmacology, 2009, Volume: 156, Issue:3

    Topics: Animals; Chemokines, CXC; Cholestasis; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocyte Rolling; Liver; Liver Diseases; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Peroxidase; Simvastatin

2009
Potential hepato-protective effect of α-tocopherol or simvastatin in aged rats.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:3

    Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Antioxidants; Catalase; Lipids; Liver; Liver Diseases; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Simvastatin; Thiobarbituric Acid Reactive Substances

2012
Simvastatin attenuates cisplatin-induced kidney and liver damage in rats.
    Toxicology, 2007, Feb-12, Volume: 230, Issue:2-3

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Bilirubin; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Cisplatin; Creatinine; Female; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; L-Lactate Dehydrogenase; Liver Diseases; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley; Serum Albumin; Simvastatin

2007
Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system).
    The American journal of cardiology, 2007, Feb-01, Volume: 99, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Atorvastatin; Chemical and Drug Induced Liver Injury; Drug Prescriptions; Drug Therapy, Combination; Dyslipidemias; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver Diseases; Lovastatin; Niacin; Pravastatin; Prevalence; Pyrroles; Retrospective Studies; Rhabdomyolysis; Risk Factors; Simvastatin; United States; United States Food and Drug Administration

2007
Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats.
    Journal of hepatology, 2007, Volume: 46, Issue:6

    Topics: Animals; Anticholesteremic Agents; Carbon Tetrachloride; Cyclic GMP; Liver; Liver Cirrhosis; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Perfusion; Phosphorylation; Rats; Rats, Wistar; Simvastatin

2007
I take Zocor for high cholesterol. My doctor checks my lipid levels every six months and they have been pretty good for a few years now. But he also checks my liver-function tests, because liver damage is one of the side effects of this drug. How worried
    Harvard heart letter : from Harvard Medical School, 1998, Volume: 9, Issue:1

    Topics: Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Liver Function Tests; Simvastatin

1998