simvastatin has been researched along with Leukemia, Myeloid, Acute in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, L; Li, B; Qiang, T; Tian, H; Wang, J | 1 |
| Chen, Q; Ding, L; Fang, Z; Li, G; Li, Y; Lu, Z; Xu, B; Yao, J; Yu, L | 1 |
| Batlle, M; Montané, E; Ribera, JM; Vives, S | 1 |
| de Jonge-Peeters, SD; de Vries, EG; Kuipers, F; van der Weide, K; Vellenga, E | 1 |
| de Vries, EG; Korthuis, PM; Kuipers, F; van der Weide, K; Vellenga, E | 1 |
| de Jonge-Peeters, S; de Vries, EG; Fehrmann, RS; Huls, G; Kuipers, F; Schuringa, JJ; van der Weide, K; Vellenga, E | 1 |
| Bar-Sef, A; Elis, A; Fabian, I; Lishner, M | 1 |
7 other study(ies) available for simvastatin and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Simvastatin regulates the proliferation, apoptosis, migration and invasion of human acute myeloid leukemia cells via miR-19a-3p/HIF-1α axis.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Leukemic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia, Myeloid, Acute; MicroRNAs; Neoplasm Invasiveness; Signal Transduction; Simvastatin | 2021 |
Simvastatin Preferentially Targets FLT3/ITD Acute Myeloid Leukemia by Inhibiting MEK/ERK and p38-MAPK Signaling Pathways.
Topics: Animals; Apoptosis; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Mevalonic Acid; Mice; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Signal Transduction; Simvastatin | 2023 |
[Rhabdomyolysis and renal failure secondary to interaction between simvastatin, ciclosporin A and risperidone in an allogeneic stem cell transplantation patient].
Topics: Acute Kidney Injury; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Postoperative Complications; Rhabdomyolysis; Risperidone; Simvastatin; Stem Cell Transplantation; Transplantation, Homologous | 2008 |
Combining simvastatin with the farnesyltransferase inhibitor tipifarnib results in an enhanced cytotoxic effect in a subset of primary CD34+ acute myeloid leukemia samples.
Topics: Anticholesteremic Agents; Antigens, CD34; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Drug Therapy, Combination; Farnesyltranstransferase; Humans; Leukemia, Myeloid, Acute; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin | 2009 |
Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.
Topics: Butadienes; Extracellular Signal-Regulated MAP Kinases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Nitriles; Prenylation; ras Proteins; Simvastatin | 2012 |
Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.
Topics: Adult; Aged; Aged, 80 and over; Animals; Bone Marrow Cells; Cholesterol; Drug Screening Assays, Antitumor; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prenylation; Protein Processing, Post-Translational; Simvastatin; Tumor Cells, Cultured; Young Adult | 2012 |
Effect of simvastatin alone and in combination with cytosine arabinoside on the proliferation of myeloid leukemia cell lines.
Topics: Anticholesteremic Agents; Antimetabolites, Antineoplastic; Cell Division; Cytarabine; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Simvastatin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2001 |