Page last updated: 2024-08-23

simvastatin and Leukemia, Myeloid, Acute

simvastatin has been researched along with Leukemia, Myeloid, Acute in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Ji, L; Li, B; Qiang, T; Tian, H; Wang, J1
Chen, Q; Ding, L; Fang, Z; Li, G; Li, Y; Lu, Z; Xu, B; Yao, J; Yu, L1
Batlle, M; Montané, E; Ribera, JM; Vives, S1
de Jonge-Peeters, SD; de Vries, EG; Kuipers, F; van der Weide, K; Vellenga, E1
de Vries, EG; Korthuis, PM; Kuipers, F; van der Weide, K; Vellenga, E1
de Jonge-Peeters, S; de Vries, EG; Fehrmann, RS; Huls, G; Kuipers, F; Schuringa, JJ; van der Weide, K; Vellenga, E1
Bar-Sef, A; Elis, A; Fabian, I; Lishner, M1

Other Studies

7 other study(ies) available for simvastatin and Leukemia, Myeloid, Acute

ArticleYear
Simvastatin regulates the proliferation, apoptosis, migration and invasion of human acute myeloid leukemia cells via miR-19a-3p/HIF-1α axis.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Leukemic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia, Myeloid, Acute; MicroRNAs; Neoplasm Invasiveness; Signal Transduction; Simvastatin

2021
Simvastatin Preferentially Targets FLT3/ITD Acute Myeloid Leukemia by Inhibiting MEK/ERK and p38-MAPK Signaling Pathways.
    Drugs in R&D, 2023, Volume: 23, Issue:4

    Topics: Animals; Apoptosis; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Mevalonic Acid; Mice; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Signal Transduction; Simvastatin

2023
[Rhabdomyolysis and renal failure secondary to interaction between simvastatin, ciclosporin A and risperidone in an allogeneic stem cell transplantation patient].
    Medicina clinica, 2008, Nov-15, Volume: 131, Issue:17

    Topics: Acute Kidney Injury; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Postoperative Complications; Rhabdomyolysis; Risperidone; Simvastatin; Stem Cell Transplantation; Transplantation, Homologous

2008
Combining simvastatin with the farnesyltransferase inhibitor tipifarnib results in an enhanced cytotoxic effect in a subset of primary CD34+ acute myeloid leukemia samples.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, May-01, Volume: 15, Issue:9

    Topics: Anticholesteremic Agents; Antigens, CD34; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Drug Therapy, Combination; Farnesyltranstransferase; Humans; Leukemia, Myeloid, Acute; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin

2009
Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.
    Leukemia, 2012, Volume: 26, Issue:4

    Topics: Butadienes; Extracellular Signal-Regulated MAP Kinases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Nitriles; Prenylation; ras Proteins; Simvastatin

2012
Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.
    Experimental hematology, 2012, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Animals; Bone Marrow Cells; Cholesterol; Drug Screening Assays, Antitumor; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prenylation; Protein Processing, Post-Translational; Simvastatin; Tumor Cells, Cultured; Young Adult

2012
Effect of simvastatin alone and in combination with cytosine arabinoside on the proliferation of myeloid leukemia cell lines.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2001, Volume: 49, Issue:4

    Topics: Anticholesteremic Agents; Antimetabolites, Antineoplastic; Cell Division; Cytarabine; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Simvastatin; Tumor Cells, Cultured; Tumor Stem Cell Assay

2001