simvastatin has been researched along with Left Ventricular Hypertrophy in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Caproni, KP; Dos Santos, L; Garcia, JAD; Martins, ÂM; Miranda, LPA; Silva Sarto, DAQ; Silva, J; Souza Carvalho, MDG; Souza, PS; Ureña, MJE; Vilas Boas, BM | 1 |
| Han, L; Liu, ZH; Qi, H; Yang, X; Zhao, C; Zou, C | 1 |
| Cioffi, G; Cramariuc, D; Devereux, RB; Gerdts, E; Lønnebakken, MT; Pedersen, TR; Rogge, BP; Rossebø, AB | 1 |
| Bonney, W; Cheema, FH; Gonzalez, AM; Homma, S; Kinnear, C; Liao, JK; Mahmut, N; Martens, TP; Mital, S; Osorio, JC | 1 |
| Adamcova, M; Bednarova, K; Krajcirovicova, K; Mullerova, M; Paulis, L; Pechanova, O; Pelouch, V; Simko, F | 1 |
| Cramariuc, D; Gerdts, E; Rieck, AE; Tuseth, N; Wachtell, K | 1 |
| Cramariuc, D; Gerdts, E; Gohlke-Bärwolf, C; Lund, BP; Rieck, AE; Rossebø, AB | 1 |
| Huang, C; Liu, Z; Shen, Z; Wang, Z; Zhu, J | 1 |
| He, WK; He, ZC; Lai, Q; Liang, LY; Lu, DF; Luo, JD; Pan, XD; Wang, W; Wen, YH; Xiao, AY; Zeng, ZH | 1 |
| Boman, K; Devereux, RB; Egstrup, K; Gohlke-Baerwolf, C; Greve, AM; Kesäniemi, YA; Køber, L; Nienaber, C; Ray, S; Rossebø, AB; Wachtell, K; Willenheimer, R | 1 |
| Boman, K; Cramariuc, D; Gerdts, E; Gohlke-Bärwolf, C; Lønnebakken, MT; Rieck, ÅE; Rossebø, AB; Staal, EM | 1 |
| Arcucci, O; Avvedimento, EV; Cardone, L; Cavuto, L; Chiariello, M; Cittadini, A; Coppola, C; Curcio, A; Di Lorenzo, E; Indolfi, C; Perrino, C; Sacca, L; Stingone, AM; Torella, D | 1 |
| Coelho, OR; Franchini, KG; Lagosta, VJ; Moreno, H; Nadruz, W | 1 |
| Chen, MS; Luo, JD; Wang, YZ; Xu, FP; Yi, Q; Zhang, GP; Zhang, HQ | 1 |
| Chang, NC; Chou, TF; Lee, TM; Lin, MS | 1 |
| Chen, YQ; Li, AG; Shang, FJ; Wang, B; Xue, YS; Zhao, LY; Zheng, QS | 1 |
| Laverty, R; Ledingham, JM | 1 |
| Elrod, JW; Greer, JJ; Jones, SP; Kakkar, AK; Lefer, DJ; Watson, LJ | 1 |
| Guan, JX; Liu, XH; Luo, JD; Zhang, GP; Zhang, WW | 1 |
| Chen, X; Guan, JX; Luo, JD; Zhang, GP; Zhang, WW | 1 |
| Luo, JD; Ou, HJ; Zhang, GP; Zhang, WW; Zhong, BH | 1 |
5 trial(s) available for simvastatin and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Relation of Left Ventricular Mass to Prognosis in Initially Asymptomatic Mild to Moderate Aortic Valve Stenosis.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Drug Therapy, Combination; Echocardiography; Ezetimibe; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Simvastatin | 2015 |
Effect of obesity on left ventricular mass and systolic function in patients with asymptomatic aortic stenosis (a Simvastatin Ezetimibe in Aortic Stenosis [SEAS] substudy).
Topics: Aged; Aged, 80 and over; Angiography; Aortic Valve Stenosis; Azetidines; Body Mass Index; Double-Blind Method; Drug Therapy, Combination; Echocardiography, Doppler; Ezetimibe; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Logistic Models; Male; Middle Aged; Multivariate Analysis; Obesity; Probability; Prognosis; Risk Assessment; Severity of Illness Index; Simvastatin; Stroke Volume; Systole; Treatment Outcome | 2010 |
The effects of simvastatin on left ventricular hypertrophy and left ventricular function in patients with essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Lipids; Male; Simvastatin; Telmisartan; Treatment Outcome; Ultrasonography; Ventricular Function, Left | 2011 |
Clinical implications of electrocardiographic left ventricular strain and hypertrophy in asymptomatic patients with aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis study.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Azetidines; Cardiovascular Diseases; Drug Therapy, Combination; Electrocardiography; Ezetimibe; Female; Follow-Up Studies; Heart Failure; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Infarction; Prognosis; Simvastatin; Ventricular Dysfunction, Left | 2012 |
Hypertension in aortic stenosis: implications for left ventricular structure and cardiovascular events.
Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Antihypertensive Agents; Aortic Valve Stenosis; Azetidines; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Echocardiography; Ezetimibe; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Simvastatin | 2012 |
16 other study(ies) available for simvastatin and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Grape juice attenuates left ventricular hypertrophy in dyslipidemic mice.
Topics: Animals; Blood Pressure; C-Reactive Protein; CD40 Ligand; Collagen; Diet, High-Fat; Dyslipidemias; Fruit and Vegetable Juices; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Protective Agents; Receptors, LDL; Simvastatin; Vitis | 2020 |
Simvastatin activates the PPARγ-dependent pathway to prevent left ventricular hypertrophy associated with inhibition of RhoA signaling.
Topics: Animals; Disease Models, Animal; Fibrosis; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Myocardium; PPAR gamma; Rabbits; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Simvastatin; Transcription Factor RelA; Ultrasonography | 2013 |
Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor.
Topics: Animals; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Signal Transduction; Simvastatin; Stroke Volume; Ultrasonography | 2008 |
Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; Hypertrophy, Left Ventricular; Kidney; Male; Melatonin; Mineralocorticoid Receptor Antagonists; NF-kappa B; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Simvastatin; Spironolactone; Ventricular Remodeling | 2009 |
Asymmetric septal hypertrophy - a marker of hypertension in aortic stenosis (a SEAS substudy).
Topics: Aortic Valve Stenosis; Azetidines; Biomarkers; Cardiomegaly; Cardiomyopathy, Hypertrophic; Ezetimibe; Female; Heart Atria; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Simvastatin | 2010 |
Simvastatin prevents ERK activation in myocardial hypertrophy of spontaneously hypertensive rats.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Blotting, Western; Body Weight; Disease Progression; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Wistar; Signal Transduction; Simvastatin; Time Factors | 2010 |
Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation.
Topics: Animals; Echocardiography; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Simvastatin; Ventricular Pressure | 2002 |
Simvastatin prevents load-induced protein tyrosine nitration in overloaded hearts.
Topics: Animals; Antioxidants; Aorta; Constriction; Coronary Vessels; Enzyme Induction; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Isoenzymes; Male; Membrane Transport Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Oxidative Stress; Phosphoproteins; Pressure; Proteins; Rats; Rats, Wistar; Simvastatin; Tyrosine; Ventricular Remodeling | 2004 |
Statins initiated after hypertrophy inhibit oxidative stress and prevent heart failure in rats with aortic stenosis.
Topics: Animals; Aortic Coarctation; Aortic Valve Stenosis; Apoptosis; Atrial Natriuretic Factor; Cardiac Output, Low; Caspase 3; Caspases; Chronic Disease; Heart Ventricles; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Oxidative Stress; Rats; RNA, Messenger; Simvastatin; Superoxides | 2004 |
Effect of simvastatin on left ventricular mass in hypercholesterolemic rabbits.
Topics: Animals; Cholesterol; Electrocardiography; Endothelin-1; Hypercholesterolemia; Hypertrophy, Left Ventricular; Hypolipidemic Agents; Linear Models; Long QT Syndrome; Male; Myocytes, Cardiac; Perfusion; Rabbits; RNA, Messenger; Simvastatin | 2005 |
[Effects of simvastatin on the left ventricular hypertrophy in spontaneously hypertensive rats and its relationship with the expression of protein kinase B].
Topics: Animals; Hypertension; Hypertrophy, Left Ventricular; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Simvastatin | 2005 |
Effects of glitazones on blood pressure and vascular structure in mesenteric resistance arteries and basilar artery from genetically hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Basilar Artery; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Mesenteric Arteries; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Wistar; Rosiglitazone; Simvastatin; Tetrazoles; Thiazolidinediones; Tunica Media; Valine; Valsartan | 2005 |
Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure.
Topics: Animals; Gene Expression Regulation, Enzymologic; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Infarction; Nitric Oxide Synthase Type III; Pulmonary Edema; Severity of Illness Index; Simvastatin; Survival Rate; Ventricular Dysfunction, Left | 2006 |
Effects of simvastatin on left ventricular hypertrophy and function in rats with aortic stenosis.
Topics: Animals; Aortic Valve Stenosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypertrophy, Left Ventricular; Male; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Simvastatin; Ventricular Function, Left | 1999 |
Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Blood Pressure; Captopril; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypertrophy, Left Ventricular; Organ Size; Peptidyl-Dipeptidase A; Rats; Simvastatin; Time Factors | 1999 |
Effects of simvastatin on activities of endogenous antioxidant enzymes and angiotensin-converting enzyme in rat myocardium with pressure-overload cardiac hypertrophy.
Topics: Animals; Antioxidants; Aorta, Thoracic; Catalase; Constriction; Glutathione Peroxidase; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Simvastatin; Superoxide Dismutase | 2002 |