simvastatin and Ischemia

Topics: Animals; Intestinal Diseases; Ischemia; Male; Mesenteric Ischemia; Nitric Oxide Synthase Type II; Pulmonary Artery; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Simvastatin

Topics: Animals; Cardiovascular Agents; Diabetes Mellitus, Experimental; Hindlimb; Immunohistochemistry; Ischemia; Magnetic Resonance Imaging; Male; Metformin; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Oligopeptides; Simvastatin

Topics: Animals; Bone Density Conservation Agents; Clodronic Acid; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Femur Head; Femur Head Necrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Pilot Projects; Simvastatin; Swine; Swine, Miniature; Treatment Outcome; X-Ray Microtomography

Topics: Animals; Blood Flow Velocity; Collateral Circulation; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Progenitor Cells; Ezetimibe; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Mice; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphorylation; Recovery of Function; Regional Blood Flow; Simvastatin; Streptozocin; Time Factors; Vascular Endothelial Growth Factor A; Vasodilation

Topics: Adaptor Proteins, Signal Transducing; Aged; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Case-Control Studies; Cells, Cultured; Critical Illness; Endothelial Cells; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammasomes; Ischemia; Male; Middle Aged; NLR Proteins; Peripheral Arterial Disease; Simvastatin; Transcription, Genetic; Up-Regulation

Topics: Animals; Capillaries; Disease Models, Animal; Gene Expression Regulation; Hindlimb; Ischemia; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred BALB C; Multimodal Imaging; Muscles; Neovascularization, Physiologic; Oligopeptides; Regional Blood Flow; Simvastatin; Technetium; Tomography, Emission-Computed, Single-Photon; Vascular Endothelial Growth Factor A

Topics: Animals; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Ischemia; Lymphocyte Function-Associated Antigen-1; Muscle, Skeletal; Neutrophil Infiltration; Neutrophils; Simvastatin

Topics: Actins; Animals; Anticholesteremic Agents; Cattle; Cell Movement; Cell Proliferation; Cholesterol; Diabetic Retinopathy; Endothelial Cells; Endothelium, Vascular; Ischemia; Nitric Oxide; Oncogene Protein v-akt; Phosphorylation; Retinal Neovascularization; Retinal Vessels; Simvastatin

Topics: Adult; Alanine Transaminase; Anterior Compartment Syndrome; Aspartate Aminotransferases; C-Reactive Protein; Creatinine; Female; Fibula; Functional Laterality; Humans; Ischemia; Leg; Muscle, Skeletal; Muscular Diseases; Myoglobin; Myoglobinuria; Simvastatin; Tibia; Tomography, X-Ray Computed; Treatment Outcome

Topics: Animals; Antioxidants; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Diseases; Ischemia; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Simvastatin; Superoxide Dismutase; Treatment Outcome; Tumor Necrosis Factor-alpha

Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Combined Modality Therapy; Female; Flow Cytometry; Hindlimb; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Simvastatin; Vascular Endothelial Growth Factor A

Topics: Analysis of Variance; Animals; Apoptosis; Cell Movement; Cell Proliferation; Green Fluorescent Proteins; Hindlimb; Hydrogen Peroxide; Ischemia; Laser-Doppler Flowmetry; Mesenchymal Stem Cell Transplantation; Mice; Mice, Transgenic; Neovascularization, Physiologic; Simvastatin

Topics: Animals; Hindlimb; Intercellular Adhesion Molecule-1; Ischemia; Lung; Lung Injury; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Simvastatin; Transcription Factor RelA

Topics: Acyl Coenzyme A; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Cell Movement; Cells, Cultured; Guanine Nucleotide Exchange Factors; Hindlimb; Humans; Hydroxyeicosatetraenoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Mevalonic Acid; Mice; Mice, Knockout; Neovascularization, Physiologic; Neuropeptides; Prenylation; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Rho Guanine Nucleotide Exchange Factors; Simvastatin

Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Enzyme Induction; Heme Oxygenase-1; In Situ Nick-End Labeling; Injections, Intraperitoneal; Ischemia; Male; Metalloporphyrins; Protoporphyrins; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin; Testis

Topics: Angiogenesis Inducing Agents; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Capillaries; Diabetes Complications; Disease Models, Animal; Heme Oxygenase-1; Hindlimb; Ischemia; Male; Neovascularization, Physiologic; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Simvastatin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vitamin E; Vitamins

Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Ischemia; Lung; Lung Diseases; Male; Models, Cardiovascular; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Long-Evans; Reperfusion Injury; Simvastatin; Statistics as Topic; Time Factors; Transcription Factors; Treatment Outcome

Topics: Analysis of Variance; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Iohexol; Ischemia; Kidney; Male; Microcirculation; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin; Time Factors; Vasoconstrictor Agents

Topics: Aged; Biopsy; Colitis; Colon, Descending; Colon, Transverse; Colonoscopy; Diagnosis, Differential; Follow-Up Studies; Humans; Hyperlipidemias; Hypolipidemic Agents; Ischemia; Male; Simvastatin

Topics: Aged; Atorvastatin; Blood Platelets; Cholesterol, LDL; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Heart Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Pyrroles; Simvastatin; Ticlopidine; Time Factors; Wound Healing

Topics: Angiogenic Proteins; Animals; Blood Pressure; Chronic Disease; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Kidney Diseases; Microcirculation; Neovascularization, Physiologic; Renal Artery Obstruction; Simvastatin; Swine; Transglutaminases

Topics: Animals; Diabetes Mellitus, Experimental; Edema; Glutathione; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Malondialdehyde; Muscle, Skeletal; Necrosis; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Simvastatin; Time Factors; Tourniquets

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Endothelial Cells; Hindlimb; Ischemia; Mice; Mice, Nude; Neovascularization, Physiologic; Simvastatin; Stem Cell Transplantation; Treatment Outcome; Up-Regulation

Topics: Adenosine Diphosphate; Animals; Cell Fractionation; Glutamic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Liver; Lovastatin; Male; Mitochondria, Liver; Oxygen Consumption; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Succinates

Topics: Adult; Aged; Arteriosclerosis; Disease Progression; Female; Humans; Hypolipidemic Agents; Ischemia; Male; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome