simvastatin has been researched along with Injuries, Spinal Cord in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bayar, MA; Celik, H; Erdem, Y; Karatay, M; Sahin, O; Sertbas, I; Tascioglu, T; Tekiner, A | 1 |
| Chen, HJ; Cho, CL; Liang, CL; Liliang, PC; Lu, K; Tsai, YD; Wang, HK; Wang, KW | 1 |
| Gao, K; Guo, Y; Han, D; Mei, X; Shen, Z; Song, C; Yuan, Y | 1 |
| Bi, J; Gao, K; Han, D; Li, H; Mei, X; Wan, Z; Wang, G; Wang, Y; Yao, T; Yuan, Y | 1 |
| Han, SH; Hwang, JY; Kim, J; Park, JW; Park, S; Ryu, JH; Sohn, HM | 1 |
| Doolen, S; Holmberg, E; Kluge, BR; Sarmiere, PD; White, JT; Zhang, SX | 1 |
| Hillyer, J; Kwon, BK; Lee, JH; Mann, CM; Stammers, AM; Tetzlaff, W | 1 |
| Kwon, BK; Lee, JH; Liu, J; Stammers, AM; Streijger, F; Tetzlaff, W; Tigchelaar, S | 1 |
| Chen, Z; Dang, G; Han, X; Liu, Z; Song, C; Xu, Y; Yang, N; Zhu, J | 1 |
| Bramanti, P; Capuano, A; Cuzzocrea, S; Donniacuo, M; Esposito, E; Impellizzeri, D; Mazzon, E; Paterniti, I; Rinaldi, B | 1 |
| Cui, Y; Dang, G; Han, X; Song, C; Xu, Y; Yang, N | 1 |
| Laskowitz, DT; Lynch, JR; McGirt, MJ; Woodworth, GF | 1 |
12 other study(ies) available for simvastatin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Simvastatin in an experimental spinal cord injury model: a histopathological and biochemical evidence based study.
Topics: Animals; Disease Models, Animal; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Simvastatin; Spinal Cord; Spinal Cord Injuries | 2020 |
Simvastatin and Simvastatin-Ezetimibe Improve the Neurological Function and Attenuate the Endothelial Inflammatory Response after Spinal Cord Injury in Rat.
Topics: Animals; Anticholesteremic Agents; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Inflammation; Male; Motor Activity; Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Simvastatin; Spinal Cord Injuries | 2019 |
Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β-catenin signaling pathway after spinal cord injury.
Topics: Animals; Apoptosis; beta Catenin; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipopolysaccharides; Locomotion; Male; Movement Disorders; Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Signal Transduction; Simvastatin; Spinal Cord; Spinal Cord Injuries; Time Factors; Wnt Proteins | 2016 |
Neuroprotective Effect of Simvastatin via Inducing the Autophagy on Spinal Cord Injury in the Rat Model.
Topics: Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain-Derived Neurotrophic Factor; Cardiovascular Diseases; Disease Models, Animal; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Humans; Microtubule-Associated Proteins; Neuroprotective Agents; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Simvastatin; Spinal Cord Injuries; TOR Serine-Threonine Kinases | 2015 |
Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions.
Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glucose; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Motor Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Reperfusion Injury; Simvastatin; Spinal Cord Injuries | 2017 |
Statins decrease chondroitin sulfate proteoglycan expression and acute astrocyte activation in central nervous system injury.
Topics: Animals; Astrocytes; Blotting, Western; Brain Injuries; Cells, Cultured; Cerebral Cortex; Chondroitin Sulfate Proteoglycans; Glial Fibrillary Acidic Protein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Male; Motor Activity; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Spinal Cord Injuries | 2008 |
Lack of robust neurologic benefits with simvastatin or atorvastatin treatment after acute thoracic spinal cord contusion injury.
Topics: Analysis of Variance; Animals; Atorvastatin; Benzenesulfonates; Dietary Sucrose; Disease Models, Animal; Drug Administration Routes; Ectodysplasins; Exploratory Behavior; Food, Formulated; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Motor Activity; Nervous System Diseases; Pain Measurement; Pain Threshold; Psychomotor Performance; Pyrroles; Rats; Rats, Sprague-Dawley; Sacrococcygeal Region; Simvastatin; Spinal Cord Injuries | 2010 |
Lack of neuroprotective effects of simvastatin and minocycline in a model of cervical spinal cord injury.
Topics: Animals; Cervical Vertebrae; Disease Models, Animal; Drug Therapy, Combination; Minocycline; Myelitis; Nerve Regeneration; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Simvastatin; Spinal Cord Injuries; Treatment Failure | 2010 |
Simvastatin treatment improves functional recovery after experimental spinal cord injury by upregulating the expression of BDNF and GDNF.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Evoked Potentials, Somatosensory; Female; Gene Expression; Glial Cell Line-Derived Neurotrophic Factor; Immunohistochemistry; Motor Activity; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Simvastatin; Spinal Cord Injuries; Up-Regulation | 2011 |
Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; PPAR alpha; Random Allocation; Simvastatin; Spinal Cord Injuries; Thoracic Vertebrae | 2012 |
Simvastatin mobilizes bone marrow stromal cells migrating to injured areas and promotes functional recovery after spinal cord injury in the rat.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Brain-Derived Neurotrophic Factor; Cell Movement; Female; Motor Activity; Multipotent Stem Cells; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Simvastatin; Spinal Cord; Spinal Cord Injuries; Stromal Cells; Vascular Endothelial Growth Factor A | 2012 |
Synthes Award for Resident Research in Spinal Cord & Spinal Column Injury: Statins for the treatment of neurological injury: a role beyond cholesterol lowering.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Awards and Prizes; Brain Injuries; Heptanoic Acids; Hypercholesterolemia; Immunoblotting; Interleukin-6; Internship and Residency; Mice; Pyrroles; Research; RNA, Messenger; Simvastatin; Spinal Cord Injuries; Subarachnoid Hemorrhage | 2004 |