simvastatin has been researched along with Infarction, Middle Cerebral Artery in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kerner, V; Kum, S; Pande, SD; Safdar Husain, F | 1 |
| Alcazar, A; Ayuso, MI; Campos-Martorell, M; Canals, F; Chacón, P; García-Bonilla, L; Hernández-Guillamon, M; Monge, M; Montaner, J; Rosell, A; Salvador, N | 1 |
| Lu, C; Qiao, ZW; Xia, CM; Zhu, DN; Zhu, MX | 1 |
| Campos-Martorell, M; Cano-Sarabia, M; Hernández-Guillamon, M; Maspoch, D; Montaner, J; Rosell, A; Simats, A | 1 |
| Fan, YH; Lam, WW; Mok, VC; Ng, PW; Tsoi, TH; Wong, A; Wong, KS; Yeung, V | 1 |
| Chen, XY; Lam, WW; Leung, TW; Liu, R; Mok, VC; Ng, PW; Soo, Y; Tsoi, TH; Wong, A; Wong, KS; Yeung, V | 1 |
| Chen, J; Chopp, M; Cui, X; Lu, M; Roberts, C; Savant-Bhonsale, S; Zacharek, A | 1 |
| Chu, W; Fu, JH; Lam, W; Mok, V; Ng, PW; Tsoi, TH; Wong, A; Wong, KS; Xiong, Y; Yeung, V | 1 |
| Chen, J; Chopp, M; Cui, X; Lu, M; Roberts, C; Shehadah, A | 1 |
| Beretta, S; Cattalini, A; de Curtis, M; Ferrarese, C; Librizzi, L; Pastori, C; Piazza, F; Sala, G | 1 |
| Charish, J; Hosseini, SK; Kaka, GR; Keshavarz, M; Pirzad Jahromi, G; Sadr, SS; Seidi, S; Shabanzadeh, AP; Sohanaki, H | 1 |
| Rasmussen, JG; Simonsen, U | 1 |
| Du, D; Liu, M; Shen, L; Wang, J; Xia, C; Zhu, D; Zhu, M | 1 |
| Granger, DN; Jin, R; Li, G; Liu, L; Nanda, A; Zhu, X | 1 |
| Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W | 1 |
| Balduini, W; Carloni, S; Cimino, M; Gelosa, P; Guerrini, U; Sironi, L; Tremoli, E | 1 |
| Banfi, C; Brioschi, M; Cimino, M; Gelosa, P; Gianella, A; Guerrini, U; Nobili, E; Paoletti, R; Sironi, L; Tremoli, E | 1 |
| Gao, F; Song, T; Wu, JM; Zhang, J; Zhou, FY | 1 |
| Cakmak, A; Dalkara, T; Dinçer, D; Köksoy, C; Yazgan, U; Yemişçi, M | 1 |
1 review(s) available for simvastatin and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Neuroprotective effect of simvastatin in stroke: a comparison between adult and neonatal rat models of cerebral ischemia.
Topics: Aging; Animals; Animals, Newborn; Brain Ischemia; Disease Models, Animal; Enzyme Activation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Nitric Oxide Synthase Type III; Simvastatin; Stroke | 2005 |
3 trial(s) available for simvastatin and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Effects of statins on the progression of cerebral white matter lesion: Post hoc analysis of the ROCAS (Regression of Cerebral Artery Stenosis) study.
Topics: Aged; Brain Mapping; Cerebral Arteries; Cerebral Cortex; Dementia, Vascular; Disease Progression; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Intracranial Arteriosclerosis; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Fibers, Myelinated; Placebos; Severity of Illness Index; Simvastatin; Treatment Outcome | 2009 |
Statins for asymptomatic middle cerebral artery stenosis: The Regression of Cerebral Artery Stenosis study.
Topics: Aged; Constriction, Pathologic; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Middle Aged; Outcome Assessment, Health Care; Pilot Projects; Severity of Illness Index; Simvastatin; Treatment Outcome | 2009 |
Effects of statins on progression of subclinical brain infarct.
Topics: Aged; China; Disease Progression; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors; Simvastatin; Time Factors; Treatment Outcome | 2010 |
15 other study(ies) available for simvastatin and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Complete resolution of extensive thrombosis of atheromatous non-aneurysmal descending aorta and pulmonary embolism with warfarin therapy.
Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Brain; Carotid Stenosis; Drug Therapy, Combination; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Middle Aged; Plaque, Atherosclerotic; Pulmonary Embolism; Simvastatin; Stroke; Warfarin | 2018 |
Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model.
Topics: Animals; Blotting, Western; Brain; Brain Chemistry; Electrophoresis, Gel, Two-Dimensional; HSP90 Heat-Shock Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Intracranial Embolism; Male; Neurologic Examination; Proteomics; Rats; Rats, Wistar; Simvastatin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stroke | 2014 |
Simvastatin pretreatment protects cerebrum from neuronal injury by decreasing the expressions of phosphor-CaMK II and AQP4 in ischemic stroke rats.
Topics: Animals; Aquaporin 4; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebrum; Cholesterol; Down-Regulation; Hypolipidemic Agents; Infarction, Middle Cerebral Artery; Male; Neurons; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Simvastatin | 2014 |
Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats.
Topics: Animals; Biological Availability; Blood-Brain Barrier; Brain; Brain Ischemia; Drug Delivery Systems; Infarction, Middle Cerebral Artery; Kidney; Liposomes; Liver; Lung; Male; Rats, Wistar; Simvastatin; Spleen; Stroke; Tissue Distribution | 2016 |
Chemokine, vascular and therapeutic effects of combination Simvastatin and BMSC treatment of stroke.
Topics: Analysis of Variance; Animals; Blood Vessels; Bone Marrow Cells; Bone Marrow Transplantation; Bromodeoxyuridine; Cell Movement; Chemokine CXCL12; Disease Models, Animal; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Neovascularization, Physiologic; Neurologic Examination; Rats; Rats, Wistar; Receptors, CXCR4; Recovery of Function; Simvastatin; Stromal Cells | 2009 |
Combination treatment of experimental stroke with Niaspan and Simvastatin, reduces axonal damage and improves functional outcome.
Topics: Amyloid beta-Protein Precursor; Animals; Axons; Brain; Brain Ischemia; Calcium-Binding Proteins; Delayed-Action Preparations; Disease Models, Animal; Drug Therapy, Combination; GPI-Linked Proteins; Infarction, Middle Cerebral Artery; Male; Microfilament Proteins; Microglia; Myelin Proteins; Neuroprotective Agents; Niacin; Nogo Receptor 1; Random Allocation; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Peptide; Simvastatin; Stroke; Treatment Outcome | 2010 |
Acute lipophilicity-dependent effect of intravascular simvastatin in the early phase of focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Electrophysiology; Guinea Pigs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Infusions, Intravenous; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Oxidation-Reduction; Proto-Oncogene Proteins c-akt; Simvastatin; Solubility; Vascular Resistance | 2011 |
Therapeutic effects of a combinatorial treatment of simvastatin and bone marrow stromal cells on experimental embolic stroke.
Topics: Animals; Behavior, Animal; Biomarkers; Bone Marrow Transplantation; Brain Edema; Cells, Cultured; Combined Modality Therapy; Disease Models, Animal; Fibronectins; Hyaluronan Receptors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Leukocyte Common Antigens; Male; Motor Activity; Rats; Rats, Wistar; Recovery of Function; Simvastatin; Stroke; Stromal Cells; Time Factors | 2012 |
Mesenchymal stromal cell therapy and treatment of ischaemic disease.
Topics: Animals; Bone Marrow Transplantation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Simvastatin; Stroke; Stromal Cells | 2012 |
Upregulation of protein phosphatase 2A and NR3A-pleiotropic effect of simvastatin on ischemic stroke rats.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Gene Expression Regulation; Genetic Pleiotropy; Infarction, Middle Cerebral Artery; Male; Okadaic Acid; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Simvastatin; Stroke; Up-Regulation | 2012 |
Simvastatin attenuates stroke-induced splenic atrophy and lung susceptibility to spontaneous bacterial infection in mice.
Topics: Animals; Anticholesteremic Agents; Apoptosis; Atrophy; Bacterial Infections; bcl-2-Associated X Protein; Brain Infarction; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Infections; Interferon-gamma; Lung; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-bcl-2; Simvastatin; Spleen; Splenectomy; Stroke | 2013 |
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis | 2005 |
Activation of NF-kB and ERK1/2 after permanent focal ischemia is abolished by simvastatin treatment.
Topics: Animals; Brain; Brain Ischemia; Chemokine CCL2; Disease Models, Animal; Down-Regulation; Encephalitis; Enzyme Activation; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Interleukin-1; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; NF-kappa B; Rats; Rats, Sprague-Dawley; Simvastatin; Up-Regulation | 2006 |
[Effects of xuezhikang and simvastatin on cerebral ischemia-reperfusion injury in rat].
Topics: Animals; Brain; Brain Ischemia; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Simvastatin | 2006 |
Statin pre-treatment protects brain against focal cerebral ischemia in diabetic mice.
Topics: Animals; Brain; Brain Ischemia; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Mice; Motor Activity; Neurologic Examination; Simvastatin | 2007 |