Page last updated: 2024-08-23

simvastatin and Hypertrophy, Right Ventricular

simvastatin has been researched along with Hypertrophy, Right Ventricular in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arzt, M; Blumberg, FC; Lange, TJ; Lehmann, H; Nowrotek, A; Pfeifer, M; Schroll, S; Sebah, D; Wensel, R1
Jasińska-Stroschein, M; Kącikowska, J; Orszulak-Michalak, D; Owczarek, J; Surowiecka, A1
Ali, O; Mamanova, L; Sebkhi, A; Wharton, J; Wilkins, MR; Wojciak-Stothard, B; Yang, Q; Zhao, L1
Liu, B; Liu, HM; Wang, XM; Wang, XQ; Yu, L; Zhou, TF1
Ali, O; Bradlow, W; Ghofrani, HA; Gibbs, JS; Howard, L; Mohiaddin, RH; Nihoyannopoulos, P; Rhodes, CJ; Taegtmeyer, A; Wharton, J; Wilkins, MR1
Liu, CP; Lu, WX; Yu, BX; Zhang, WH; Zhang, YJ1
Ji, YQ; Liu, CP; Lu, WX; Zeng, Q; Zhang, WH; Zhang, YJ1
Berry, GJ; Faul, JL; Kao, PN; Nishimura, T; Pearl, RG; Qiu, D; Vaszar, LT1
Benson, G; Berry, GJ; Faul, JL; Kao, PN; Nishimura, T; Pearl, RG; Qiu, D; Shi, L; Vaszar, LT; Zhao, G1

Trials

1 trial(s) available for simvastatin and Hypertrophy, Right Ventricular

ArticleYear
Simvastatin as a treatment for pulmonary hypertension trial.
    American journal of respiratory and critical care medicine, 2010, May-15, Volume: 181, Issue:10

    Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Simvastatin; Ultrasonography; Young Adult

2010

Other Studies

8 other study(ies) available for simvastatin and Hypertrophy, Right Ventricular

ArticleYear
Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats.
    Acta physiologica (Oxford, England), 2013, Volume: 208, Issue:2

    Topics: Animals; Bleomycin; Hydroxyproline; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung Compliance; Male; Motor Activity; Natriuretic Peptide, Brain; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Simvastatin

2013
HMG-COA reductase inhibitors: An opportunity for the improvement of imatinib safety. An experimental study in rat pulmonary hypertension.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:1

    Topics: Animals; Drug Synergism; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Organ Size; Rats; Rats, Wistar; Rosuvastatin Calcium; Simvastatin

2015
Simvastatin and sildenafil combine to attenuate pulmonary hypertension.
    The European respiratory journal, 2009, Volume: 34, Issue:4

    Topics: Animals; Cyclic GMP; Disease Models, Animal; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Circulation; Purines; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Signal Transduction; Sildenafil Citrate; Simvastatin; Sulfones

2009
Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats.
    Experimental lung research, 2009, Volume: 35, Issue:5

    Topics: Animals; Blood Pressure; Blotting, Western; Cell Proliferation; Disease Models, Animal; Down-Regulation; GATA6 Transcription Factor; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Time Factors

2009
Simvastatin protects against the development of monocrotaline-induced pulmonary hypertension in rats via a heme oxygenase-1-dependent pathway.
    Experimental lung research, 2011, Volume: 37, Issue:8

    Topics: Animals; Arterioles; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-6; Lung; Monocrotaline; Protoporphyrins; Rats; Rats, Sprague-Dawley; Signal Transduction; Simvastatin

2011
Additive effect of tadalafil and simvastatin on monocrotaline-induced pulmonary hypertension rats.
    Scandinavian cardiovascular journal : SCJ, 2012, Volume: 46, Issue:6

    Topics: Animals; Antihypertensive Agents; Arterial Pressure; Arterioles; Carbolines; Disease Models, Animal; Drug Therapy, Combination; Familial Primary Pulmonary Hypertension; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Interleukin-6; Male; Monocrotaline; Phosphodiesterase 5 Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Simvastatin; Tadalafil; Time Factors; Vasodilator Agents

2012
Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.
    American journal of respiratory and critical care medicine, 2002, Nov-15, Volume: 166, Issue:10

    Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organ Size; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Treatment Outcome; Tunica Intima

2002
Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.
    Circulation, 2003, Sep-30, Volume: 108, Issue:13

    Topics: Animals; Apoptosis; Arterial Occlusive Diseases; Cell Division; Gene Expression Profiling; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Lung; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Simvastatin; Survival Analysis; Tunica Intima

2003