Page last updated: 2024-08-23

simvastatin and Hyperplasia

simvastatin has been researched along with Hyperplasia in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Gong, YM; Hu, XC; Huang, T; Liu, S; Wang, X; Xu, Y1
Cai, C; Kilari, S; Korley, JN; Misra, S; Simeon, M; Singh, A; von Recum, HA; Zhao, C; Zuckerman, ST1
Bhattacharya, S; Janardhanan, R; Kong, H; Leof, EB; Mandrekar, J; Misra, S; Mukhopadhyay, D; Roy, B; Vohra, P; Withers, S; Yang, B1
Alexopoulos, D; Apostolakis, E; Hahalis, G; Koniari, I; Mavrilas, D; Papadaki, H; Papadimitriou, E; Papalois, A; Poimenidi, E; Xanthopoulou, I1
Bailey, I; Bruch, D; Desai, P; Gahtan, V; Helkin, A; Maier, KG1
Boskabady, MH; Golchoobian, R; Jahromi, GP; Kashani, IR; Mohammadian, M; Nejad, AK; Omidi, A; Sadeghipour, HR1
Afergan, E; Ben David, M; Danenberg, HD; Epstein, H; Gilhar, D; Golomb, G; Koroukhov, N; Rohekar, K1
An, J; Chen, L; Chen, P; Chen, YJ; Liu, DS; Sun, BB; Wang, HX; Wang, T; Wang, X; Wen, FQ; Xu, D1
Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA1
Amoroso, G; Ciabatti, N; De Carlo, M; Limbruno, U; Mariani, M; Micheli, A; Papini, B; Petronio, AS1
Dol, F; Herbert, J; Mares, A1
Auch-Schwelk, W; Elsner, M; Mach, S; Schächinger, V; Walter, DH; Zeiher, AM1

Trials

1 trial(s) available for simvastatin and Hyperplasia

ArticleYear
Simvastatin does not inhibit intimal hyperplasia and restenosis but promotes plaque regression in normocholesterolemic patients undergoing coronary stenting: a randomized study with intravascular ultrasound.
    American heart journal, 2005, Volume: 149, Issue:3

    Topics: Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Male; Middle Aged; Premedication; Simvastatin; Stents; Ultrasonography, Interventional

2005

Other Studies

11 other study(ies) available for simvastatin and Hyperplasia

ArticleYear
Simvastatin inhibits prostatic hyperplasia in rats with metabolic syndrome.
    International urology and nephrology, 2022, Volume: 54, Issue:9

    Topics: Animals; Diet, High-Fat; Hyperplasia; Insulin-Like Growth Factor I; Interleukin-6; Lipids; Male; Metabolic Syndrome; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Simvastatin; Tumor Necrosis Factor-alpha

2022
Periadventitial Delivery of Simvastatin-Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula.
    Journal of the American Heart Association, 2020, 12-15, Volume: 9, Issue:24

    Topics: Animals; Anticholesteremic Agents; Arteriovenous Fistula; Chemokine CCL2; Cyclodextrins; Drug Delivery Systems; Fibrosis; Graft Occlusion, Vascular; Hyperplasia; Inflammation; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Models, Animal; Neointima; Simvastatin; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Vascular Remodeling; Veins

2020
Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model.
    Kidney international, 2013, Volume: 84, Issue:2

    Topics: Actins; Animals; Apoptosis; Arteriovenous Shunt, Surgical; Carotid Arteries; Caspase 3; Cell Movement; Cell Proliferation; Cell Transdifferentiation; Constriction, Pathologic; Disease Models, Animal; Graft Occlusion, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Jugular Veins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Myofibroblasts; Neointima; NIH 3T3 Cells; Renal Dialysis; Signal Transduction; Simvastatin; Time Factors; Vascular Endothelial Growth Factor A

2013
Inhibition of Atherosclerosis Progression, Intimal Hyperplasia, and Oxidative Stress by Simvastatin and Ivabradine May Reduce Thoracic Aorta's Stiffness in Hypercholesterolemic Rabbits.
    Journal of cardiovascular pharmacology and therapeutics, 2016, Volume: 21, Issue:4

    Topics: Animals; Antioxidants; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Benzazepines; Diet, Atherogenic; Disease Models, Animal; Disease Progression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperplasia; Ivabradine; Male; Neointima; Oxidative Stress; Plaque, Atherosclerotic; Rabbits; Simvastatin; Vascular Stiffness

2016
Rat strain determines statin effect on intimal hyperplasia after carotid balloon injury.
    Journal of vascular surgery, 2016, Volume: 63, Issue:2

    Topics: Administration, Oral; Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Injuries; Disease Models, Animal; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Indoles; Male; Neointima; Rats, Sprague-Dawley; Rats, Zucker; Simvastatin; Species Specificity

2016
Evaluation of Simvastatin and Bone Marrow-Derived Mesenchymal Stem Cell Combination Therapy on Airway Remodeling in a Mouse Asthma Model.
    Lung, 2016, Volume: 194, Issue:5

    Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cell Movement; Collagen; Combined Modality Therapy; Disease Models, Animal; Eosinophils; Fibrosis; Goblet Cells; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Leukocyte Count; Male; Mesenchymal Stem Cell Transplantation; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Pneumonia; Simvastatin

2016
Liposomal simvastatin attenuates neointimal hyperplasia in rats.
    The AAPS journal, 2010, Volume: 12, Issue:2

    Topics: Animals; Carotid Artery Injuries; Catheterization; Cell Proliferation; Cells, Cultured; Chemistry, Pharmaceutical; Drug Delivery Systems; Graft Occlusion, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Liposomes; Male; Monocytes; Rats; Simvastatin

2010
Simvastatin attenuates acrolein-induced mucin production in rats: involvement of the Ras/extracellular signal-regulated kinase pathway.
    International immunopharmacology, 2010, Volume: 10, Issue:6

    Topics: Acrolein; Animals; Anti-Inflammatory Agents, Non-Steroidal; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Goblet Cells; GTP Phosphohydrolases; Humans; Hyperplasia; Lung; Male; Mevalonic Acid; Mucin 5AC; Phosphorylation; Pneumonia; Prenylation; ras Proteins; Rats; Rats, Sprague-Dawley; Simvastatin

2010
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
    Translational research : the journal of laboratory and clinical medicine, 2010, Volume: 156, Issue:6

    Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, Animal; Goblet Cells; Hydroxyproline; Hyperplasia; Immunohistochemistry; Inflammation; Lung; Mice; Nitrates; Nitrites; Ovalbumin; Simvastatin; Transforming Growth Factor beta1

2010
Simvastatin inhibits myointimal hyperplasia following carotid artery injury in cholesterol-fed rabbits.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:8

    Topics: Animals; Anticholesteremic Agents; Carotid Arteries; Cell Division; Cholesterol, Dietary; Diet, Atherogenic; Hyperplasia; Lovastatin; Rabbits; Simvastatin; Tunica Intima

1996
Effect of statin therapy on restenosis after coronary stent implantation.
    The American journal of cardiology, 2000, Apr-15, Volume: 85, Issue:8

    Topics: Anticholesteremic Agents; Atorvastatin; Case-Control Studies; Coronary Angiography; Coronary Disease; Disease-Free Survival; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hyperplasia; Indoles; Lovastatin; Male; Middle Aged; Pyrroles; Recurrence; Retrospective Studies; Simvastatin; Stents; Time Factors; Tunica Intima

2000