Page last updated: 2024-08-23

simvastatin and Huntington Disease

simvastatin has been researched along with Huntington Disease in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalonia, H; Kumar, A; Mishra, J; Sharma, N1
Cepeda, C; Chen, JY; Deng, G; Faull, KF; Hwang, L; Jung, ME; Levine, MS; Tran, C1
Bernardi, G; Fusco, FR; Giampà, C; Martorana, A; Patassini, S1
Alberch, J; Canals, JM; del Toro, D; Humbert, S; Pol, A; Saudou, F; Xifró, X1

Other Studies

4 other study(ies) available for simvastatin and Huntington Disease

ArticleYear
Synergistical neuroprotection of rofecoxib and statins against malonic acid induced Huntington's disease like symptoms and related cognitive dysfunction in rats.
    European journal of pharmacology, 2013, Jun-05, Volume: 709, Issue:1-3

    Topics: Animals; Atorvastatin; Behavior, Animal; Brain; Cognition Disorders; Cyclooxygenase 2 Inhibitors; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Heptanoic Acids; Huntington Disease; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Male; Malonates; Neurons; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Simvastatin; Sulfones

2013
Partial Amelioration of Peripheral and Central Symptoms of Huntington's Disease via Modulation of Lipid Metabolism.
    Journal of Huntington's disease, 2016, Volume: 5, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Cholesterol; Diet, Ketogenic; Female; Huntington Disease; Inhibitory Postsynaptic Potentials; Lipid Metabolism; Male; Mice; Patch-Clamp Techniques; Simvastatin; Weight Loss

2016
Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease.
    Neuroscience letters, 2008, Dec-19, Volume: 448, Issue:1

    Topics: Animals; bcl-2-Associated X Protein; Calcium-Binding Proteins; Eliminative Behavior, Animal; Huntington Disease; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Parvalbumins; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-bcl-2; Quinolinic Acid; Rats; Rats, Wistar; Simvastatin; Time Factors

2008
Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease.
    Journal of neurochemistry, 2010, Volume: 115, Issue:1

    Topics: Animals; Anticholesteremic Agents; beta-Cyclodextrins; Brain; Caveolin 1; Cell Membrane; Cell Survival; Cells, Cultured; Cholesterol; DNA; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Indicators and Reagents; Membrane Microdomains; Mice; Mice, Transgenic; N-Methylaspartate; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Simvastatin; Transfection; Triglycerides

2010