simvastatin has been researched along with Huntington Disease in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalonia, H; Kumar, A; Mishra, J; Sharma, N | 1 |
| Cepeda, C; Chen, JY; Deng, G; Faull, KF; Hwang, L; Jung, ME; Levine, MS; Tran, C | 1 |
| Bernardi, G; Fusco, FR; Giampà, C; Martorana, A; Patassini, S | 1 |
| Alberch, J; Canals, JM; del Toro, D; Humbert, S; Pol, A; Saudou, F; Xifró, X | 1 |
4 other study(ies) available for simvastatin and Huntington Disease
| Article | Year |
|---|---|
Synergistical neuroprotection of rofecoxib and statins against malonic acid induced Huntington's disease like symptoms and related cognitive dysfunction in rats.
Topics: Animals; Atorvastatin; Behavior, Animal; Brain; Cognition Disorders; Cyclooxygenase 2 Inhibitors; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Heptanoic Acids; Huntington Disease; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Male; Malonates; Neurons; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Simvastatin; Sulfones | 2013 |
Partial Amelioration of Peripheral and Central Symptoms of Huntington's Disease via Modulation of Lipid Metabolism.
Topics: 3-Hydroxybutyric Acid; Animals; Cholesterol; Diet, Ketogenic; Female; Huntington Disease; Inhibitory Postsynaptic Potentials; Lipid Metabolism; Male; Mice; Patch-Clamp Techniques; Simvastatin; Weight Loss | 2016 |
Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease.
Topics: Animals; bcl-2-Associated X Protein; Calcium-Binding Proteins; Eliminative Behavior, Animal; Huntington Disease; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Parvalbumins; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-bcl-2; Quinolinic Acid; Rats; Rats, Wistar; Simvastatin; Time Factors | 2008 |
Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease.
Topics: Animals; Anticholesteremic Agents; beta-Cyclodextrins; Brain; Caveolin 1; Cell Membrane; Cell Survival; Cells, Cultured; Cholesterol; DNA; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Indicators and Reagents; Membrane Microdomains; Mice; Mice, Transgenic; N-Methylaspartate; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Simvastatin; Transfection; Triglycerides | 2010 |