simvastatin has been researched along with Glial Cell Tumors in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, W; Qi, X; Qian, Y | 1 |
| He, Y; Huang, Y; Jiao, Z; Kang, X; Liu, T; Mo, X; Shi, M; Zheng, Z; Zhong, H | 1 |
| Chopp, M; Jiang, H; Lu, D; Mahmood, A; Qu, C; Wu, H; Xiong, Y; Zhou, D | 1 |
| Buller, B; Chopp, M; Nallani, A; Santra, K; Santra, M; Santra, S | 1 |
| Bumbasirevic, V; Harhaji-Trajkovic, L; Janjetovic, K; Micic, D; Misirkic, M; Ristic, B; Sumarac-Dumanovic, M; Tovilovic, G; Trajkovic, V; Vilimanovich, U; Vucicevic, L | 1 |
| Arnold, H; Gliemroth, J; Terzis, AJ; Zulewski, H | 1 |
| Altiok, N; Ersoz, M; Koyuturk, M | 1 |
| Altiok, N; Ersoz, M; Karpuz, V; Koyuturk, M | 1 |
| Baetta, R; Butti, G; Davegna, C; De Renzis, MR; Fumagalli, R; Magrassi, L; Mazzini, G; Paoletti, R; Pezzotta, S; Soma, MR | 1 |
| Baetta, R; Battaini, F; Bergamaschi, S; Davegna, C; De Renzis, MR; Fumagalli, R; Govoni, S; Soma, MR | 1 |
| Abe, T; Kikuchi, T; Nagata, Y | 1 |
| Goto, S; Goto, T; Kochi, M; Murakami, M; Saito, Y; Ushio, Y | 1 |
| Corsini, A; Paoletti, R; Soma, MR | 1 |
| Butti, G; Fumagalli, R; Pagliarini, P; Paoletti, P; Paoletti, R; Soma, MR | 1 |
1 review(s) available for simvastatin and Glial Cell Tumors
| Article | Year |
|---|---|
Cholesterol and mevalonic acid modulation in cell metabolism and multiplication.
Topics: Animals; Cell Division; Cholesterol; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Muscles; Simvastatin | 1992 |
13 other study(ies) available for simvastatin and Glial Cell Tumors
| Article | Year |
|---|---|
Efficacy of a novel glioma therapy based on ferroptosis induced by layered double hydroxide loaded with simvastatin.
Topics: Animals; Cell Line, Tumor; Ferroptosis; Glioma; Hydroxides; Simvastatin | 2023 |
Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Fenretinide; Glioma; Humans; Lactoferrin; Macrophages; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Oxidative Stress; Simvastatin | 2018 |
Effect of simvastatin on glioma cell proliferation, migration, and apoptosis.
Topics: Analysis of Variance; Annexin A5; Anticholesteremic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colony-Forming Units Assay; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glioma; Humans; Membrane Microdomains; Microscopy, Confocal; Mitochondria; Phosphatidylinositol 3-Kinases; Phosphorylation; Signal Transduction; Simvastatin; Time Factors | 2009 |
Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells.
Topics: Animals; Apoptosis; Brain Neoplasms; Caspase 3; Cell Differentiation; Cell Line, Tumor; Doublecortin Domain Proteins; Doublecortin Protein; Glioma; Humans; Male; Microfilament Proteins; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 8; Neoplastic Stem Cells; Nerve Tissue Proteins; Neuropeptides; Protein Phosphatase 1; Rats; Simvastatin | 2011 |
Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Membrane Proteins; Mice; Microtubule-Associated Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; RNA Interference; Signal Transduction; Simvastatin; TOR Serine-Threonine Kinases; Transfection | 2012 |
Migration, proliferation, and invasion of human glioma cells following treatment with simvastatin.
Topics: Animals; Brain; Cell Division; Cell Movement; Coculture Techniques; Dose-Response Relationship, Drug; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neoplasm Invasiveness; Rats; Rats, Wistar; Simvastatin; Spheroids, Cellular; Time Factors; Tumor Cells, Cultured | 2003 |
Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via c-jun N-terminal kinase.
Topics: Activating Transcription Factor 2; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; DNA Fragmentation; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-jun; Simvastatin; Time Factors; Transcription Factors | 2004 |
Ginkgo biloba extract regulates differentially the cell death induced by hydrogen peroxide and simvastatin.
Topics: Activating Transcription Factor 2; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Ginkgo biloba; Glioma; Humans; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Immunoprecipitation; Neuroglia; Oxidants; Oxidative Stress; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; Simvastatin | 2006 |
In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin.
Topics: Animals; Astrocytoma; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Rats; Rats, Sprague-Dawley; Simvastatin; Tumor Cells, Cultured | 1995 |
PKC activity in rat C6 glioma cells: changes associated with cell cycle and simvastatin treatment.
Topics: Animals; Astrocytoma; Cell Cycle; Demecolcine; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyurea; Lovastatin; Mevalonic Acid; Protein Kinase C; Rats; Simvastatin; Tumor Cells, Cultured | 1994 |
In vitro and in vivo antiproliferative effects of simvastatin, an HMG-CoA reductase inhibitor, on human glioma cells.
Topics: Animals; Enzyme Inhibitors; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins, LDL; Lovastatin; Mice; Mice, Nude; Simvastatin; Tumor Cells, Cultured | 1997 |
The inhibitory effect of simvastatin on growth in malignant gliomas--with special reference to its local application with fibrin glue spray in vivo.
Topics: Animals; Cell Adhesion; Cell Division; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Fibrin Tissue Adhesive; Fibroblasts; Flow Cytometry; Glioma; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Nick-End Labeling; Lung; Rats; Rats, Wistar; Rhodamines; Simvastatin; Tissue Adhesives; Tumor Cells, Cultured | 2001 |
Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells.
Topics: Anticholesteremic Agents; Carmustine; Cell Count; Cell Division; Culture Media; Dose-Response Relationship, Drug; Drug Synergism; Glioma; Humans; Hydroxymethylglutaryl CoA Reductases; Interferon-beta; Lovastatin; Simvastatin; Tumor Cells, Cultured | 1992 |