Page last updated: 2024-08-23

simvastatin and Germinoblastoma

simvastatin has been researched along with Germinoblastoma in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Baba, K; Kambayashi, S; Kobayashi, K; Okuda, M1
Cai, DQ; Kim, CS; Kim, DH; Kim, SK; Lee, KJ; Qi, XF; Qin, JW; Wu, Z; Yu, YH; Zheng, L1
Cohen, JI; Katano, H; Pesnicak, L1
Cohen, JI1
Aoyama, T; Hara, S; Iwata, H; Kami, M; Kanda, Y; Matsuo, K; Mori, S; Murashige, N; Mutou, Y; Odawara, M; Suzuki, R; Tachibana, S; Takeuchi, K; Yamane, M1
Bloem, AC; Bogers, LH; de Weerdt, O; Kramer, MH; Lokhorst, HM; van de Donk, NW; van der Griend, R; van der Spek, E; Wittebol, S1

Reviews

1 review(s) available for simvastatin and Germinoblastoma

ArticleYear
HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.
    British journal of cancer, 2005, May-09, Volume: 92, Issue:9

    Topics: Animals; Cell Transformation, Viral; Enzyme Inhibitors; Herpesvirus 4, Human; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphoma; Mice; Simvastatin

2005

Trials

1 trial(s) available for simvastatin and Germinoblastoma

ArticleYear
Dose-finding study of high-dose simvastatin combined with standard chemotherapy in patients with relapsed or refractory myeloma or lymphoma.
    Haematologica, 2006, Volume: 91, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Humans; Lymphoma; Maximum Tolerated Dose; Multiple Myeloma; Recurrence; Salvage Therapy; Simvastatin; Treatment Outcome

2006

Other Studies

4 other study(ies) available for simvastatin and Germinoblastoma

ArticleYear
Effect of simvastatin on cell proliferation and Ras activation in canine tumour cells.
    Veterinary and comparative oncology, 2021, Volume: 19, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dog Diseases; Dogs; Gene Expression Regulation, Neoplastic; Hemangiosarcoma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphoma; Melanoma; ras Proteins; Simvastatin

2021
HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway.
    Cell death & disease, 2013, Feb-28, Volume: 4

    Topics: Acetylcysteine; Acyl Coenzyme A; Animals; Antioxidants; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lymphoma; Membrane Potential, Mitochondrial; Mevalonic Acid; Mice; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Reactive Oxygen Species; Signal Transduction; Simvastatin

2013
Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Apr-06, Volume: 101, Issue:14

    Topics: Animals; Apoptosis; Cell Line, Transformed; Cell Transformation, Viral; Humans; Lymphoma; Mice; Mice, SCID; NF-kappa B; Simvastatin; Viral Matrix Proteins

2004
Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.
    Cancer science, 2006, Volume: 97, Issue:2

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Japan; Lymphoma; Male; Multiple Myeloma; Pravastatin; Risk Factors; Simvastatin

2006