Page last updated: 2024-08-23

simvastatin and Gastrointestinal Hemorrhage

simvastatin has been researched along with Gastrointestinal Hemorrhage in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (83.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Arora, V; Choudhary, A; Jindal, A; Kumar, G; Sarin, SK; Vijayaraghavan, R1
Albrecht, J; Aytaman, A; Baffy, G; Bajaj, J; Garcia-Tsao, G; Hernaez, R; Hunt, K; Ioannou, G; Johnson, K; Kanwal, F; Kaplan, DE; Lee, TH; Mehta, R; Monto, A; Pandya, P; Schaubel, D; Taddei, TH1
Bosch, J; Iwakiri, Y1
Baiges, A; Bosch, J; Hernández-Gea, V1
Hauta-Aho, M; Helin-Salmivaara, A; Huupponen, R; Kastarinen, H; Korhonen, MJ; Rikala, M; Tiittanen, P1
Abraldes, JG; Tandon, P1
da Silva, AC; Kunz, DG; Marchiori, RC; Mattos, DE; Pollo-Flores, P; Rezende, GF; Santos, UC; Soldan, M1
Abraldes, JG; Albillos, A; Aracil, C; Bosch, J; Calleja, JL; Castellote, J; García-Pagán, JC; Genesca, J; Hernandez-Guerra, M; Rodriguez, M; Torres, F; Turnes, J; Villanueva, C1
Connolly, JG; Gagne, JJ1
Hong, JM; Lee, JS; Lim, SG; Park, RW; Shin, D; Yoon, D1
Abraldes, JG; Bosch, J; García-Calderó, H; García-Pagán, JC; Gracia-Sancho, J; Lozano, JJ; Meireles, CZ; Pasarin, M1
Chaudhry, T; Dillon, A; Rowe, IA1

Reviews

2 review(s) available for simvastatin and Gastrointestinal Hemorrhage

ArticleYear
The portal hypertension syndrome: etiology, classification, relevance, and animal models.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Animals; Ascites; Carcinoma, Hepatocellular; Early Detection of Cancer; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Healthy Lifestyle; Hemorrhage; Hepatic Encephalopathy; Hepatic Veins; Humans; Hypertension, Portal; Hypolipidemic Agents; Ligation; Liver Cirrhosis; Liver Neoplasms; Models, Animal; Prognosis; Simvastatin

2018
Pharmacologic prevention of variceal bleeding and rebleeding.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Atorvastatin; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Incidence; Liver; Liver Cirrhosis; Nitric Oxide Synthase Type III; Portal Pressure; Propanolamines; Propranolol; Simvastatin; Splanchnic Circulation

2018

Trials

4 trial(s) available for simvastatin and Gastrointestinal Hemorrhage

ArticleYear
Hemodynamic Effects of Adding Simvastatin to Carvedilol for Primary Prophylaxis of Variceal Bleeding: A Randomized Controlled Trial.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Carvedilol; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemodynamics; Hepatic Veins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Primary Prevention; Simvastatin; Treatment Outcome; Venous Pressure

2020
SACRED: Effect of simvastatin on hepatic decompensation and death in subjects with high-risk compensated cirrhosis: Statins and Cirrhosis: Reducing Events of Decompensation.
    Contemporary clinical trials, 2021, Volume: 104

    Topics: Esophageal and Gastric Varices; Fibrosis; Gastrointestinal Hemorrhage; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Cirrhosis; Liver Neoplasms; Prospective Studies; Retrospective Studies; Simvastatin

2021
Three months of simvastatin therapy vs. placebo for severe portal hypertension in cirrhosis: A randomized controlled trial.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2015, Volume: 47, Issue:11

    Topics: Aged; Double-Blind Method; Endosonography; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Portal Pressure; Simvastatin; Treatment Outcome; Ultrasonography, Doppler, Color; Venous Pressure

2015
Addition of Simvastatin to Standard Therapy for the Prevention of Variceal Rebleeding Does Not Reduce Rebleeding but Increases Survival in Patients With Cirrhosis.
    Gastroenterology, 2016, Volume: 150, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Combined Modality Therapy; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Ligation; Liver Cirrhosis; Male; Middle Aged; Proportional Hazards Models; Recurrence; Rhabdomyolysis; Risk Factors; Simvastatin; Spain; Time Factors; Treatment Outcome

2016

Other Studies

6 other study(ies) available for simvastatin and Gastrointestinal Hemorrhage

ArticleYear
Statins do not Increase the Rate of Bleeding Among Warfarin Users.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:2

    Topics: Aged; Anticoagulants; Drug Interactions; Female; Finland; Gastrointestinal Hemorrhage; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Hemorrhages; Male; Middle Aged; Retrospective Studies; Risk Factors; Simvastatin; Thromboembolism; Treatment Outcome; Warfarin

2018
Therapies: Drugs, Scopes and Transjugular Intrahepatic Portosystemic Shunt--When and How?
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4

    Topics: Adrenergic beta-Antagonists; Antibiotic Prophylaxis; Anticholesteremic Agents; Balloon Occlusion; Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Ligation; Liver Cirrhosis; Portasystemic Shunt, Transjugular Intrahepatic; Simvastatin; Stents

2015
Comparison of Calipers for Matching on the Disease Risk Score.
    American journal of epidemiology, 2016, 05-15, Volume: 183, Issue:10

    Topics: Aged; Aged, 80 and over; Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Cardiovascular Diseases; Cohort Studies; Computer Simulation; Cyclooxygenase 2 Inhibitors; Epidemiologic Methods; Ezetimibe; Female; Gastrointestinal Hemorrhage; Humans; Male; Medicare; Models, Theoretical; Monte Carlo Method; Odds Ratio; Osteoporotic Fractures; Prognosis; Propensity Score; Raloxifene Hydrochloride; Risk Assessment; Simvastatin; United States

2016
Comparison of the Risk of Gastrointestinal Bleeding among Different Statin Exposures with Concomitant Administration of Warfarin: Electronic Health Record-Based Retrospective Cohort Study.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Aged; Anticoagulants; Atorvastatin; Atrial Fibrillation; Drug Interactions; Electronic Health Records; Female; Gastrointestinal Hemorrhage; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Male; Middle Aged; Pravastatin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Rosuvastatin Calcium; Simvastatin; Software; Tertiary Care Centers; Warfarin

2016
Simvastatin Attenuates Liver Injury in Rodents with Biliary Cirrhosis Submitted to Hemorrhage/Resuscitation.
    Shock (Augusta, Ga.), 2017, Volume: 47, Issue:3

    Topics: Animals; Gastrointestinal Hemorrhage; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Rats; Simvastatin

2017
Uncertain Benefits of Simvastatin in the Treatment of Patients With Variceal Hemorrhage.
    Gastroenterology, 2016, Volume: 151, Issue:5

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Simvastatin; Varicose Veins

2016