Page last updated: 2024-08-23

simvastatin and Femoral Fractures

simvastatin has been researched along with Femoral Fractures in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Fechete, R; Micu, AM; Orban, E; Pap, Z; Sipos, RS1
Anil, S; Chalisserry, EP; Nam, SY1
Chen, YH; Daluiski, A; Dusad, A; Fehringer, EV; Goldring, SR; Jia, Z; Li, F; Purdue, PE; Ren, K; Wang, D; Yuan, H; Zhang, Y1
Güney, A; Kafadar, İH; Karaman, İ; Karaman, ZF; Koçer, A; Koçer, D; Öner, M1
Dos Santos Kotake, BG; Ervolino, E; Gonçalves Gonzaga, M; Ingraci de Lucia, C; Issa, JP; Macedo, AP; Mizusaki Iyomasa, D; Tocchini de Figueiredo, FA1
Daluiski, A; Dusad, A; Fehringer, EV; Goldring, SR; Jia, Z; Purdue, PE; Ren, K; Wang, D; Wei, X; Yuan, H; Zhang, Y1
Aspenberg, P; Forslund, C; Skoglund, B1
Adah, F; Benghuzzi, H; England, B; Olivier, J; Russell, G; Tsao, A; Tucci, M1
Adah, F; Benghuzzi, H; England, B; Russell, G; Tucci, M2
Aspenberg, P; Skoglund, B1
Skoglund, B1

Other Studies

12 other study(ies) available for simvastatin and Femoral Fractures

ArticleYear
Callus formation in albino Wistar rats after femur fracture assessed by visible spectroscopy.
    Biochemical and biophysical research communications, 2022, 12-17, Volume: 634

    Topics: Animals; Bony Callus; Eosine Yellowish-(YS); Female; Femoral Fractures; Femur; Fenofibrate; Fracture Healing; Hematoxylin; Humans; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Simvastatin; Spectrum Analysis

2022
Simvastatin Loaded Nano Hydroxyapatite in Bone Regeneration: A Study in the Rabbit Femoral Condyle.
    Current drug delivery, 2019, Volume: 16, Issue:6

    Topics: Animals; Bone Density; Bone Regeneration; Durapatite; Femoral Fractures; Nanoparticles; Rabbits; Simvastatin

2019
Simvastatin prodrug micelles target fracture and improve healing.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Feb-28, Volume: 200

    Topics: Animals; Cell Line; Drug Liberation; Femoral Fractures; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Micelles; Osteotomy; Polyethylene Glycols; Prodrugs; Simvastatin

2015
The effects of locally applied simvastatin on an experimental mouse femur nonunion model.
    Acta orthopaedica et traumatologica turcica, 2014, Volume: 48, Issue:6

    Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Chi-Square Distribution; Disease Models, Animal; Femoral Fractures; Follow-Up Studies; Fracture Healing; Fractures, Ununited; Injections, Intralesional; Male; Mice; Mice, Inbred Strains; Osteocalcin; Osteotomy; Postoperative Care; Radiography; Random Allocation; Reference Values; Risk Assessment; Simvastatin

2014
The effect of simvastatin treatment on bone repair of femoral fracture in animal model.
    Growth factors (Chur, Switzerland), 2015, Volume: 33, Issue:2

    Topics: Animals; Bone and Bones; Disease Models, Animal; Female; Femoral Fractures; Fracture Healing; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Osteoporosis; Rats; Rats, Wistar; Simvastatin; Stainless Steel

2015
The Evaluation of Therapeutic Efficacy and Safety Profile of Simvastatin Prodrug Micelles in a Closed Fracture Mouse Model.
    Pharmaceutical research, 2016, Volume: 33, Issue:8

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Femoral Fractures; Fractures, Closed; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Micelles; Prodrugs; Simvastatin; Treatment Outcome

2016
Simvastatin improves fracture healing in mice.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:11

    Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Femoral Fractures; Femur; Fracture Healing; Male; Mice; Mice, Inbred BALB C; Simvastatin

2002
Evaluation of the male reproductive organs after treatment with continuous sustained delivery of statin for fracture healing.
    Biomedical sciences instrumentation, 2005, Volume: 41

    Topics: Animals; Cholesterol; Delayed-Action Preparations; Femoral Fractures; Fracture Healing; Genitalia, Male; Gonadal Hormones; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Rats; Rats, Sprague-Dawley; Simvastatin; Treatment Outcome

2005
Effects of sustained release of statin by means of tricalcium phosphate lysine delivery system in defect and segmental femoral injuries on certain biochemical markers in vivo.
    Biomedical sciences instrumentation, 2006, Volume: 42

    Topics: Animals; Biomarkers; Calcium Phosphates; Drug Carriers; Femoral Fractures; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin-Like Growth Factor II; Lysine; Male; Proteins; Rats; Rats, Sprague-Dawley; Simvastatin; Treatment Outcome

2006
Cholesterol production inhibitor (statin) increased bone healing in surgically created femoral defect in an animal model.
    Biomedical sciences instrumentation, 2007, Volume: 43

    Topics: Animals; Anticholesteremic Agents; Disease Models, Animal; Drug Combinations; Femoral Fractures; Femur; Fracture Healing; Male; Osteogenesis; Rats; Rats, Sprague-Dawley; Simvastatin; Treatment Outcome; Vancomycin

2007
Locally applied Simvastatin improves fracture healing in mice.
    BMC musculoskeletal disorders, 2007, Sep-27, Volume: 8

    Topics: Animals; Compressive Strength; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Fractures; Femur; Fracture Healing; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Mice; Mice, Inbred BALB C; Simvastatin; Stress, Mechanical; Weight-Bearing

2007
Linköping University Medical Dissertation No. 1033. Following the mevalonate pathway to bone heal alley.
    Acta orthopaedica. Supplementum, 2007, Volume: 78, Issue:328

    Topics: Animals; Biomechanical Phenomena; Bone and Bones; Bone Density Conservation Agents; Coated Materials, Biocompatible; Diphosphonates; Disease Models, Animal; Femoral Fractures; Fracture Healing; Fractures, Bone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibandronic Acid; Injections, Subcutaneous; Male; Mevalonic Acid; Mice; Mice, Inbred BALB C; Rats; Rats, Sprague-Dawley; Simvastatin

2007