simvastatin has been researched along with Experimental Lung Inflammation in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 15 (93.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ates, G; Kaptan, E; Ozkok, E; Tamer, S; Yorulmaz, H | 1 |
| Rostron, AJ; Simpson, AJ | 1 |
| Chai, CY; Chen, IJ; Chung, PW; Huang, HT; Kuo, MS; Liu, CP; Wu, BN | 1 |
| Boyd, AR; Mortensen, EM | 1 |
| Uller, L | 1 |
| He, P; Hirata, H; Inoue, K; Ito, M; Iwasaki, T; Jin, Y; Kang, S; Kida, H; Kijima, T; Kohmo, S; Kuhara, H; Kumanogoh, A; Minami, T; Nagatomo, I; Nakanishi, K; Saya, H; Suzuki, M; Tachibana, I; Takahashi, R; Takeda, Y; Tetsumoto, S; Tsujino, K | 1 |
| Carratalà, J; Dorca, J; Garcia-Vidal, C; Llopis, F; Mestre, M; Morandeira-Rego, F; Simonetti, AF; Viasus, D | 1 |
| Bolton, CE; Cockcroft, JR; Coward, WR; Harrison, TW; John, ME; Johnson, SR; Knox, AJ; McKeever, TM; Shale, DJ; Thornton, JG | 1 |
| Armaganidis, A; Dimopoulou, I; Kotanidou, A; Magkou, C; Maniatis, NA; Manitsopoulos, N; Nikitopoulou, I; Orfanos, SE; Siempos, I; Zakynthinos, SG | 1 |
| Chang, YH; Chien, LN; Chuang, MT; Lin, CF; Liu, JC | 1 |
| Boskabady, MH; Golchoobian, R; Jahromi, GP; Kashani, IR; Mohammadian, M; Nejad, AK; Omidi, A; Sadeghipour, HR | 1 |
| An, J; Chen, L; Chen, P; Chen, YJ; Liu, DS; Sun, BB; Wang, HX; Wang, T; Wang, X; Wen, FQ; Xu, D | 1 |
| Agrawal, A; Ahmad, T; Aich, J; Ghosh, B; Mabalirajan, U; Makhija, L; Sharma, A | 1 |
| Ferraro, SA; Gallo, FT; Tasat, DR; Yakisich, JS | 1 |
| Chung, MH; Lee, CS; Lee, JK; Lee, JW; Lee, YJ; Shin, MK; Sung, SH; Won, C; Yang, YM; Ye, SK; Yi, EH | 1 |
| Chakrabarti, S; Chouhan, UM; Millward, LJ | 1 |
2 trial(s) available for simvastatin and Experimental Lung Inflammation
| Article | Year |
|---|---|
The effect of simvastatin on inflammatory cytokines in community-acquired pneumonia: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Analysis of Variance; C-Reactive Protein; Community-Acquired Infections; Cytokines; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Length of Stay; Male; Middle Aged; Oxygen; Partial Pressure; Pneumonia; Prospective Studies; Simvastatin; Spain | 2015 |
Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Biomarkers; Cardiovascular Agents; Cholesterol; Double-Blind Method; England; Female; Forced Expiratory Volume; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lung; Male; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Pulse Wave Analysis; Simvastatin; Spirometry; Time Factors; Treatment Outcome; Vascular Stiffness; Vital Capacity | 2015 |
14 other study(ies) available for simvastatin and Experimental Lung Inflammation
| Article | Year |
|---|---|
Therapeutic effects of simvastatin on Galectin-3 and oxidative stress parameters in endotoxemic lung tissue.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Endotoxemia; Galectin 3; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Reductase; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Male; Oxidative Stress; Pneumonia; Rats; Rats, Wistar; Signal Transduction; Simvastatin; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2018 |
Should We Tip Our CAPs to Statins?
Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neutrophils; Pilot Projects; Pneumonia; Simvastatin | 2019 |
NO-releasing xanthine KMUP-1 bonded by simvastatin attenuates bleomycin-induced lung inflammation and delayed fibrosis.
Topics: Animals; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Clarithromycin; Disease Models, Animal; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Piperidines; Pneumonia; Pulmonary Fibrosis; Signal Transduction; Simvastatin; Time Factors; Xanthines | 2014 |
Are statins beneficial for viral pneumonia?
Topics: Animals; Chemokine CCL5; Female; Humans; Neutrophils; Pneumonia; Poly I-C; Simvastatin | 2013 |
Simvastatin-induced effects on bronchial epithelial cells from COPD donors.
Topics: Animals; Chemokine CCL5; Female; Humans; Neutrophils; Pneumonia; Poly I-C; Simvastatin | 2013 |
Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages.
Topics: Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cells, Cultured; Drug Evaluation, Preclinical; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 9; Membrane Microdomains; Mice; Mice, Inbred C57BL; Mice, Knockout; NIH 3T3 Cells; Pneumonia; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Tetraspanin 28; Tetraspanin 29; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Capillary Permeability; Disease Models, Animal; Elasticity; Endothelial Cells; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lung; Lung Compliance; Male; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Pneumonia; Pulmonary Edema; Simvastatin; Time Factors; Ventilator-Induced Lung Injury | 2015 |
Statin use associated with a reduced risk of pneumonia requiring hospitalization in patients with myocardial infarction: a nested case-control study.
Topics: Aged; Atorvastatin; Case-Control Studies; Comorbidity; Diabetes Mellitus; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart Failure; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Incidence; Indoles; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Pneumonia; Protective Factors; Retrospective Studies; Risk Factors; Simvastatin; Stroke; Taiwan | 2016 |
Evaluation of Simvastatin and Bone Marrow-Derived Mesenchymal Stem Cell Combination Therapy on Airway Remodeling in a Mouse Asthma Model.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cell Movement; Collagen; Combined Modality Therapy; Disease Models, Animal; Eosinophils; Fibrosis; Goblet Cells; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Leukocyte Count; Male; Mesenchymal Stem Cell Transplantation; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Pneumonia; Simvastatin | 2016 |
Simvastatin attenuates acrolein-induced mucin production in rats: involvement of the Ras/extracellular signal-regulated kinase pathway.
Topics: Acrolein; Animals; Anti-Inflammatory Agents, Non-Steroidal; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Goblet Cells; GTP Phosphohydrolases; Humans; Hyperplasia; Lung; Male; Mevalonic Acid; Mucin 5AC; Phosphorylation; Pneumonia; Prenylation; ras Proteins; Rats; Rats, Sprague-Dawley; Simvastatin | 2010 |
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma.
Topics: Airway Remodeling; Animals; Arginine; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Disease Models, Animal; Epithelial Cells; Epithelium; Lung; Male; Mice; Mice, Inbred BALB C; Mucus; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrosation; Pneumonia; Simvastatin; Stress, Physiological | 2011 |
Simvastatin pretreatment prevents ambient particle-induced lung injury in mice.
Topics: Air Pollutants; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Coal Ash; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Lung Injury; Male; Mice; Mice, Inbred BALB C; Particulate Matter; Pneumonia; Protective Agents; Simvastatin; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha | 2011 |
Simvastatin suppresses RANTES-mediated neutrophilia in polyinosinic-polycytidylic acid-induced pneumonia.
Topics: Animals; Anti-Inflammatory Agents; Bronchi; Cell Line, Tumor; Chemokine CCL5; Disease Models, Animal; Doxycycline; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Pneumonia; Poly I-C; RNA, Small Interfering; Simvastatin; STAT3 Transcription Factor | 2013 |
Simvastatin interaction with clarithromycin and amiodarone causing myositis.
Topics: Amiodarone; Clarithromycin; Coronary Artery Bypass; Drug Interactions; Humans; Male; Middle Aged; Myositis; Pneumonia; Simvastatin; Tachycardia, Supraventricular | 2005 |