Compounds > simvastatin
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simvastatin and Demyelinating Diseases

simvastatin has been researched along with Demyelinating Diseases in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Alasmari, AF; Alharbi, M; Alshammari, A; Assiri, MA; Kalfin, R; Kapoor, T; Kumar, N; Mehan, S; Narula, AS; Sharma, N; Suri, M1
D'Hooge, R; Gieselmann, V; Matzner, U; Stein, A; Stroobants, S1
Bolijn, MJ; Dijkstra, CD; Fluitsma, DM; Teunissen, CE; Vereyken, EJ1
Antel, JP; Bedell, BJ; Kennedy, TE; Kuhlmann, T; Ludwin, SK; Miron, VE; Owens, T; Zehntner, SP1
Li, A; Li, S; Lv, S; Ma, H; Piao, H; Sun, C; Yu, Z; Zhang, N; Zhang, Y; Zhao, H1

Other Studies

5 other study(ies) available for simvastatin and Demyelinating Diseases

ArticleYear
Forskolin, an Adenylcyclase/cAMP/CREB Signaling Activator Restoring Myelin-Associated Oligodendrocyte Destruction in Experimental Ethidium Bromide Model of Multiple Sclerosis.
    Cells, 2022, 09-06, Volume: 11, Issue:18

    Topics: Adenylyl Cyclases; Animals; Colforsin; Cytokines; Demyelinating Diseases; Donepezil; Ethidium; Fingolimod Hydrochloride; Gliotoxin; Memantine; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Nerve Growth Factors; Neurodegenerative Diseases; Oligodendroglia; Rats; Rats, Wistar; Simvastatin

2022
Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic Leukodystrophy.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2015, Volume: 23, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Central Nervous System; Chemokine CCL2; Chemokine CCL4; Demyelinating Diseases; Disease Models, Animal; Humans; Inflammation; Leukodystrophy, Metachromatic; Mice; Simvastatin; Spinal Cord; Tumor Necrosis Factor-alpha

2015
An in vitro model for de- and remyelination using lysophosphatidyl choline in rodent whole brain spheroid cultures.
    Glia, 2009, Volume: 57, Issue:12

    Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Brain; Cell Proliferation; Central Nervous System Agents; Cholesterol; Demyelinating Diseases; Lysophosphatidylcholines; Mice; Mice, Inbred C57BL; Models, Neurological; Myelin Basic Protein; Myelin Sheath; Nerve Tissue Proteins; Neuroglia; Neurons; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Simvastatin; Spheroids, Cellular; Time Factors; Transcription Factors

2009
Statin therapy inhibits remyelination in the central nervous system.
    The American journal of pathology, 2009, Volume: 174, Issue:5

    Topics: Animals; Anticholesteremic Agents; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Cell Differentiation; Cell Proliferation; Chelating Agents; Cuprizone; Demyelinating Diseases; Flow Cytometry; Fluorescent Antibody Technique; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Nerve Regeneration; Nerve Tissue Proteins; Oligodendrocyte Transcription Factor 2; Oligodendroglia; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Stem Cells; Transcription Factors; Zebrafish Proteins

2009
Simvastatin attenuates hypomyelination induced by hypoxia-ischemia in neonatal rats.
    Neurological research, 2010, Volume: 32, Issue:9

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; CD11b Antigen; Demyelinating Diseases; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Ischemia, Brain; Myelin Basic Protein; Rats; Rats, Sprague-Dawley; Simvastatin

2010