Page last updated: 2024-08-23

simvastatin and Degenerative Disc Disease

simvastatin has been researched along with Degenerative Disc Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
El-Sherbiny, IM; Khalil, IA; Yahia, S1
Bi, S; Chen, T; Feng, X; Huang, Z; Zhang, L1
C Park, Y; Haworth, K; Lin, CY; Mahoney, E; Mercado-Shekhar, KP; Nguyen, K; Pan, HY; Zhang, Z1
Khan, A; Kim, HM; Kyere, KA; La Marca, F; Lin, CY; Miyata, Y; Park, P; Park, YS; Rahman, SU; Than, KD; Than, TT; Wang, L; Zhang, H1
Chi, J; Gologorsky, Y1
Chiaro, JA; Haskins, ME; Malhotra, NR; O'Donnell, P; Ponder, KP; Shore, EM; Smith, LJ1
Hua, W; Kang, L; Li, S; Li, W; Liu, W; Song, Y; Tu, J; Wang, K; Wu, X; Yang, C; Zhang, Y1
Hollister, SJ; La Marca, F; Lin, CY; Park, JB; Park, P; Wang, L; Yang, VC; Zhang, H1

Other Studies

8 other study(ies) available for simvastatin and Degenerative Disc Disease

ArticleYear
Fortified gelatin-based hydrogel scaffold with simvastatin-mixed nanomicelles and platelet rich plasma as a promising bioimplant for tissue regeneration.
    International journal of biological macromolecules, 2023, Jan-15, Volume: 225

    Topics: Gelatin; Humans; Hydrogels; Intervertebral Disc Degeneration; Platelet-Rich Plasma; Simvastatin

2023
A new in vivo method to retard progression of intervertebral disc degeneration through stimulation of endogenous stem cells with simvastatin.
    Medical hypotheses, 2017, Volume: 101

    Topics: Animals; Anticholesteremic Agents; Cell Differentiation; Cell Movement; Cells, Cultured; Disease Progression; Glucose Transport Proteins, Facilitative; Humans; Hypoxia-Inducible Factor 1; Intervertebral Disc; Intervertebral Disc Degeneration; Mesenchymal Stem Cells; Simvastatin; Stem Cell Transplantation; Stem Cells; Wound Healing

2017
Multiple-Exposure Drug Release from Stable Nanodroplets by High-Intensity Focused Ultrasound for a Potential Degenerative Disc Disease Treatment.
    Ultrasound in medicine & biology, 2019, Volume: 45, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Extracorporeal Shockwave Therapy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intervertebral Disc; Intervertebral Disc Degeneration; Nanoparticles; Rabbits; Simvastatin

2019
Intradiscal injection of simvastatin results in radiologic, histologic, and genetic evidence of disc regeneration in a rat model of degenerative disc disease.
    The spine journal : official journal of the North American Spine Society, 2014, Jun-01, Volume: 14, Issue:6

    Topics: Animals; Bone Morphogenetic Protein 2; Disease Models, Animal; Extracellular Matrix; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Spinal; Intervertebral Disc; Intervertebral Disc Degeneration; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Regeneration; Simvastatin; Up-Regulation

2014
Statins for disc degeneration.
    Neurosurgery, 2014, Volume: 74, Issue:4

    Topics: Animals; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intervertebral Disc Degeneration; Rats; Simvastatin

2014
Effects of neonatal enzyme replacement therapy and simvastatin treatment on cervical spine disease in mucopolysaccharidosis I dogs.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014, Volume: 29, Issue:12

    Topics: Animals; Disease Models, Animal; Dog Diseases; Dogs; Enzyme Replacement Therapy; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iduronidase; Intervertebral Disc Degeneration; Male; Mucopolysaccharidosis I; Simvastatin

2014
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
    Inflammation, 2017, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Apoptosis; Cells, Cultured; Extracellular Matrix; Humans; Interleukin-1beta; Intervertebral Disc Degeneration; Middle Aged; Mitogen-Activated Protein Kinases; NF-kappa B; Nucleus Pulposus; Scoliosis; Signal Transduction; Simvastatin; Young Adult

2017
Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury.
    Arthritis research & therapy, 2009, Volume: 11, Issue:6

    Topics: Animals; Bone Morphogenetic Protein 2; Drug Carriers; Gels; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intervertebral Disc; Intervertebral Disc Degeneration; Lactic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin

2009