simvastatin has been researched along with Critical Illness in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, A; Heslegrave, A; McAuley, DF; Page, VJ; Sanders, RD; Watne, LO; Zetterberg, H | 1 |
| Casarin, A; Ely, EW; McAuley, DF; McDowell, C; Murphy, L; Page, VJ; Zhao, XB | 1 |
| Agus, A; McAuley, DF; Page, VJ; Phair, G | 1 |
| Gordon, A; McAuley, DF; O'Kane, C; Prevost, AT; Santhakumaran, S; Shankar-Hari, M | 1 |
| Agus, A; Alce, TM; Casarin, A; Ely, EW; Jackson, JC; McAuley, DF; McDowell, C; Murphy, L; Page, VJ; Zhao, X | 1 |
| Acin, F; Bleda, S; de Haro, J; Ferruelo, A; Lopez de Maturana, I; Varela, C | 1 |
| Batista, MC; Cendoroglo Neto, M; Dalboni, MA; dos Santos, OF; Durão, MS; Ferrari, GL; Iizuka, IJ; Monte, JC; Queiroz, KC; Quinto, BM | 1 |
| Reddy, K; Shah, SV | 1 |
2 trial(s) available for simvastatin and Critical Illness
| Article | Year |
|---|---|
Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Anti-Inflammatory Agents; Coma; Critical Care; Critical Illness; Delirium; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intensive Care Units; Male; Middle Aged; Respiration, Artificial; Simvastatin; Time Factors; Treatment Outcome | 2017 |
Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Anti-Inflammatory Agents; Biomarkers; Butyrylcholinesterase; Clinical Protocols; Cognition; Critical Illness; Delirium; Drug Administration Routes; England; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Intensive Care Units; Length of Stay; Neuroprotective Agents; Research Design; Respiration, Artificial; Risk Factors; Simvastatin; Time Factors; Treatment Outcome | 2015 |
6 other study(ies) available for simvastatin and Critical Illness
| Article | Year |
|---|---|
Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients.
Topics: Adult; Biomarkers; Critical Illness; Deep Sedation; Delirium; Humans; Intermediate Filaments; Length of Stay; Neurofilament Proteins; Randomized Controlled Trials as Topic; Simvastatin | 2022 |
Simvastatin for the prevention and treatment of delirium in critically ill, mechanically ventilated patients (MoDUS): a cost-effectiveness analysis.
Topics: Cost-Benefit Analysis; Critical Illness; Delirium; Humans; Intensive Care Units; Respiration, Artificial; Simvastatin | 2018 |
Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials.
Topics: Adult; Aged; Anti-Inflammatory Agents; APACHE; Cardiotonic Agents; Critical Illness; Female; Guideline Adherence; Hospital Mortality; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intensive Care Units; Male; Middle Aged; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sepsis; Simendan; Simvastatin; Treatment Outcome; Vasoconstrictor Agents; Vasopressins | 2019 |
Effect of Simvastatin Treatment on "In Vitro" NLRP1 Inflammasome Expression in Peripheral Arterial Disease.
Topics: Adaptor Proteins, Signal Transducing; Aged; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Case-Control Studies; Cells, Cultured; Critical Illness; Endothelial Cells; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammasomes; Ischemia; Male; Middle Aged; NLR Proteins; Peripheral Arterial Disease; Simvastatin; Transcription, Genetic; Up-Regulation | 2016 |
Effects of simvastatin on cytokines secretion from mononuclear cells from critically ill patients with acute kidney injury.
Topics: Acute Kidney Injury; Case-Control Studies; Critical Illness; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Monocytes; Simvastatin; Tumor Necrosis Factor-alpha | 2011 |
Rhabdomyolysis with acute renal failure triggered by the seasonal flu vaccination in a patient taking simvastatin.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Creatinine; Critical Illness; Follow-Up Studies; Hemofiltration; Humans; Influenza Vaccines; Influenza, Human; Intensive Care Units; Kidney Function Tests; Lymphoma, B-Cell; Male; Rhabdomyolysis; Risk Assessment; Simvastatin; Treatment Outcome; Vaccination | 2010 |