Page last updated: 2024-08-23

simvastatin and Chronic Kidney Failure

simvastatin has been researched along with Chronic Kidney Failure in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (16.98)	18.2507
2000's	23 (43.40)	29.6817
2010's	20 (37.74)	24.3611
2020's	1 (1.89)	2.80

Authors

Authors	Studies
Cai, C; Kilari, S; Korley, JN; Misra, S; Simeon, M; Singh, A; von Recum, HA; Zhao, C; Zuckerman, ST	1
Furukubo, T; Izumi, S; Minegaki, T; Nishiguchi, K; Nitta, A; Shimada, N; Tachiki, H; Tsujimoto, M; Tsutsui, K; Uchiyama, H; Yamakawa, T; Yoshida, T	1
Buse, JB; Craven, TE; Ismail-Beigi, F; Katz, L; Mottl, AK; Mychaleckyj, JC; Papademetriou, V; Pedley, CF; Sigal, RJ; Simmons, DL	1
Agodoa, L; Baigent, C; Cass, A; Craig, JC; de Zeeuw, D; Emberson, J; Feldt-Rasmussen, B; Fellström, B; Haynes, R; Herrington, WG; Landray, MJ; Levin, A; Lewis, D; Reith, C; Walker, R; Wheeler, DC	1
Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP	1
Bybee, KA; Lavie, CJ; O'Keefe, JH	1
Imig, JD; Knight, SF; Roy, S; Yuan, J	1
Faergeman, O; Fayyad, R; Holdaas, H; Holme, I; Kastelein, JJ; Larsen, ML; Lindahl, C; Olsson, AG; Pedersen, TR; Tikkanen, MJ	1
Cai, AJ; Chang, JP; Jiang, Y; Li, JH; Li, XY; Peng, BS; Su, ZW; Zhang, J; Zhu, SL	1
Alexopoulos, E; Belechri, AM; Dogrammatzi, F; Efstratiadis, G; Kirmizis, D; Memmos, D; Papagianni, A; Skoura, L	1
Inoue, T; Kikuta, T; Sato, T; Suzuki, H; Tsuda, M; Watanabe, Y	1
Narsipur, SS; Singh, B; Srinivasan, B	1
Turagam, M; Velagapudi, P	1
Carru, C; Deiana, L; Loriga, G; Satta, AE; Sotgia, S; Zinellu, A	1
Martin, PY; Saudan, P	1
Naghibi, M; Nazemian, F; Zahed, N	1
Leung, AA; van Walraven, C	1
Almquist, T; Farndale, RW; Hjemdahl, P; Jacobson, SH; Lins, PE	1
Alexopoulos, E; Belechri, AM; Dogrammatzi, F; Efstratiadis, G; Kirmizis, D; Memmos, D; Papagianni, A	1
Bianchi, S; Gaspardone, A	1
Li, J; Liu, FY; Liu, YH; Zhu, XP	1
Hryszko, T; Małyszko, J; Małyszko, JS; Myśliwiec, M; Pawlak, K	1
Abbott, KC; McMillan, RJ; Sheikh, AM; Viola, RA; Welch, PG; Yuan, CM	1
Hryszko, T; Malyszko, J; Malyszko, JS; Mysliwiec, M	1
Bozbas, H; Guz, G; Korkmaz, ME; Muderrisoglu, H; Ozin, MB; Tayfun, E; Yigit, F	1
Gejyo, F; Iino, N; Moro, H; Nishi, S; Nishibori, T; Shirasaki, A; Tanuma, A; Tsukada, H	1
Demirbas, A; Dinckan, A; Gurkan, A; Karatas, GU; Kececioglu, N; Kocak, H; Tuncer, M; Yakupoglu, U; Yakupoglu, YK; Yegin, O	1
Davidson, M	1
Barsotti, G; Casto, G; Consani, C; Donadio, C; Filippi, C; Franzoni, F; Galetta, F; Innocenti, M; Manca-Rizza, G; Mantuano, E; Panichi, V; Panicucci, E; Paoletti, S; Santi, S; Sbragia, G; Taccola, D; Tramonti, G	1
Barillà, A; Belghity, N; Buemi, M; Caccamo, C; Crascì, E; Floccari, F; Frisina, N; Mantuano, S; Nostro, L; Pacilè, ME; Pernice, F; Romeo, A	1
Deray, G; Isnard-Bagnis, C; Karie, S; Launay-Vacher, V	1
Cameron, AJ; Hillyard, DZ; Jardine, AG; Mark, PB; McDonald, KJ; Nutt, CD; Thomson, J; Wan, RK	1
Li, Q; Wang, D; Wang, Y; Xu, Q	1
Padial, LR	1
Drüeke, TB; Ivanovski, O; Joki, N; Ketteler, M; Lacour, B; Maizel, J; Massy, ZA; Mothu, N; Nguyen-Khoa, T; Nikolov, IG; Szumilak, D; Westenfeld, R	1
de Sévaux, R; Huussen, J; Ter Laak, H; van der Velden, W	1
Castelluccio, A; Fiorini, F; Patrone, E	1
Akçiçek, F; Alev, M; Atabay, G; Basçi, A; Duman, S; Kürsad, S; Ok, E; Unsal, A	1
Wanner, C	1
MacMahon, S; Robson, RA; Sutherland, WH; Walker, HL; Walker, RJ	1
Kimura, K; Kishino, M; Maeda, A; Maeda, T; Miyano, M; Mune, M; Nishide, I; Nishide, T; Nishikawa, O; Ogawa, A; Otani, H; Takahashi, T; Tone, Y; Yukawa, S	1
Fujigaki, Y; Hishida, A; Ikegaya, N; Suzuki, H; Togawa, A; Yonemura, K	1
Hryszko, T; Małyszko, J; Małyszko, JS; Myśliwiec, M	1
Kirisits, W; Kotanko, P; Skrabal, F	1
Morgan, C; Rigby, RJ; Saltissi, D; Westhuyzen, J	1
Masterson, TM	1
Chang, JW; Kim, SB; Lee, SK; Min, WK; Park, JS; Yang, WS	1
Angelé, B; Bellinghieri, G; Savica, V	1
Bellinghieri, G; Lamanna, F; Savica, V	1
Harris, DC; Mitchell, P; Simons, LA; Stewart, JH	1
Hörl, WH; Luley, CH; Wanner, C; Wieland, H	1

Reviews

6 review(s) available for simvastatin and Chronic Kidney Failure

Article	Year
Statins can improve proteinuria and glomerular filtration rate loss in chronic kidney disease patients, further reducing cardiovascular risk. Fact or fiction? Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:10 Topics: Acute Kidney Injury; Atorvastatin; Cardiovascular Diseases; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Renal Insufficiency, Chronic; Risk; Rosuvastatin Calcium; Simvastatin	2015
Reviewing the medical literature: five notable articles in general internal medicine from 2010 and 2011. Open medicine : a peer-reviewed, independent, open-access journal, 2012, Volume: 6, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Azetidines; Cardiomyopathies; Ezetimibe; Female; Heart Failure; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pyrazoles; Pyridones; Recurrence; Risk; Seizures; Simvastatin; Ultrasonography; Warfarin	2012
Rhabdomyolysis after simvastatin therapy in an HIV-infected patient with chronic renal failure. AIDS patient care and STDs, 2004, Volume: 18, Issue:12 Topics: Adult; Aged; Anticholesteremic Agents; Female; HIV Infections; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Rhabdomyolysis; Simvastatin	2004
Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation. Preventive cardiology, 2005,Fall, Volume: 8, Issue:4 Topics: Atorvastatin; Comorbidity; Dyslipidemias; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Kidney Failure, Chronic; Kidney Transplantation; Lovastatin; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2005
[Statins in patients with kidney failure: efficacy, tolerance, and prescription guidelines in patients with chronic kidney disease and renal transplant]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:2 Pt 1 Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Dyslipidemias; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Graft Rejection; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Kidney Failure, Chronic; Liver Transplantation; Middle Aged; Pravastatin; Primary Prevention; Prospective Studies; Proteinuria; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Renal Dialysis; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Time Factors	2006
Ezetimibe plus simvastatin cardiovascular outcomes study program. Expert review of cardiovascular therapy, 2008, Volume: 6, Issue:1 Topics: Acute Coronary Syndrome; Anticholesteremic Agents; Aortic Valve Stenosis; Atherosclerosis; Azetidines; Disease Progression; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Kidney Failure, Chronic; Simvastatin; Treatment Outcome	2008

Trials

20 trial(s) available for simvastatin and Chronic Kidney Failure

Article	Year
Long-Term Effects of Intensive Glycemic and Blood Pressure Control and Fenofibrate Use on Kidney Outcomes. Clinical journal of the American Society of Nephrology : CJASN, 2018, 11-07, Volume: 13, Issue:11 Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fenofibrate; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Simvastatin; Time Factors	2018
Effects of lowering LDL cholesterol on progression of kidney disease. Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:8 Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Disease Progression; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Incidence; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Simvastatin; Treatment Outcome	2014
Cardiovascular outcomes and their relationships to lipoprotein components in patients with and without chronic kidney disease: results from the IDEAL trial. Journal of internal medicine, 2010, Volume: 267, Issue:6 Topics: Acute Disease; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Heart Arrest; Heptanoic Acids; Humans; Kidney Failure, Chronic; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Pyrroles; Regression Analysis; Simvastatin	2010
How does short-term low-dose simvastatin influence serum prohepcidin levels in patients with end-stage renal disease? A pilot study. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2010, Volume: 14, Issue:3 Topics: Adult; Aged; Antimicrobial Cationic Peptides; C-Reactive Protein; Case-Control Studies; Female; Hepcidins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Kidney Failure, Chronic; Male; Middle Aged; Protein Precursors; Renal Dialysis; Simvastatin; Young Adult	2010
Study of Heart and Renal Protection (SHARP): randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease. American heart journal, 2010, Volume: 160, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Incidence; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Simvastatin; Treatment Outcome	2010
Effect of simvastatin use on autonomic function in patients with end stage renal disease. Cardiovascular & hematological disorders drug targets, 2011, Mar-01, Volume: 11, Issue:1 Topics: Adult; Aged; Autonomic Nervous System; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Simvastatin	2011
Oxidative stress improvement is associated with increased levels of taurine in CKD patients undergoing lipid-lowering therapy. Amino acids, 2012, Volume: 43, Issue:4 Topics: Aged; Allantoin; Azetidines; Drug Administration Schedule; Drug Combinations; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Kidney; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Simvastatin; Sulfhydryl Compounds; Superoxides; Taurine; Uric Acid	2012
Effects of lipid-lowering treatment on platelet reactivity and platelet-leukocyte aggregation in diabetic patients without and with chronic kidney disease: a randomized trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; Blood Platelets; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Blind Method; Ezetimibe; Female; Flow Cytometry; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Leukocytes; Lipids; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Prognosis; Risk Factors; Simvastatin; Young Adult	2012
The effects of vitamin E-coated membrane dialyzer compared to simvastatin in patients on chronic hemodialysis. Renal failure, 2012, Volume: 34, Issue:9 Topics: Acrylamides; Aged; Antioxidants; beta-Alanine; Biomarkers; C-Reactive Protein; Coated Materials, Biocompatible; Cross-Over Studies; Equipment Design; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; Oxidative Stress; Renal Dialysis; Simvastatin; Treatment Outcome; Vitamin E	2012
[Effects on simvastatin in continuous ambulatory peritoneal dialysis patients with hyperlipidemia]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2000, Apr-28, Volume: 25, Issue:2 Topics: Adult; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Simvastatin	2000
Comparison of intermittent with continuous simvastatin treatment in hypercholesterolemic patients with end stage renal failure. Japanese heart journal, 2004, Volume: 45, Issue:6 Topics: Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Simvastatin; Triglycerides	2004
Simvastatin therapy in lymphocyte cross-match-positive kidney transplantation candidates. Transplantation proceedings, 2005, Volume: 37, Issue:7 Topics: Adult; Female; Histocompatibility Testing; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Kidney Transplantation; Lymphocytes; Male; Simvastatin; Waiting Lists	2005
In vivo and in vitro effects of simvastatin on inflammatory markers in pre-dialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:2 Topics: Biomarkers; Cells, Cultured; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Interleukin-8; Kidney Failure, Chronic; Male; Middle Aged; Simvastatin	2006
Clinical investigation on the hypolipidemic effect of simvastatin versus probucol in hemodialysis patients. La Clinica terapeutica, 1994, Volume: 145, Issue:9 Topics: Aged; Combined Modality Therapy; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Probucol; Renal Dialysis; Simvastatin	1994
Lipid-lowering effects of simvastatin and gemfibrozil in CAPD patients: a prospective cross-over study. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1996, Volume: 12 Topics: Adult; Aged; Cholesterol; Combined Modality Therapy; Cross-Over Studies; Diet, Fat-Restricted; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Simvastatin; Triglycerides	1996
Effect of treatment with simvastatin on serum cholesteryl ester transfer in patients on dialysis. PERFECT Study Collaborative Group. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:1 Topics: Adolescent; Adult; Aged; Cholesterol Esters; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Lipids; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Simvastatin; Sterol O-Acyltransferase	1997
Effect of simvastatin on the lipid profile of hemodialysis patients. Kidney international. Supplement, 1999, Volume: 71 Topics: Aged; Apolipoproteins B; Apolipoproteins E; Cholesterol; Cholesterol, VLDL; Creatine Kinase; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Kidney Failure, Chronic; Lipids; Male; Malondialdehyde; Middle Aged; Renal Dialysis; Simvastatin; Treatment Outcome; Triglycerides	1999
Safety and efficacy of simvastatin in hypercholesterolemic patients undergoing chronic renal dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 39, Issue:2 Topics: Adult; Aged; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Simvastatin; Treatment Outcome	2002
Effects of simvastatin on high-sensitivity C-reactive protein and serum albumin in hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 39, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; C-Reactive Protein; Female; Fibrin Fibrinogen Degradation Products; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Renal Dialysis; Serum Albumin; Simvastatin	2002
Effects of HMG-CoA reductase inhibitors in hypercholesterolemic patients on hemodialysis. Kidney international, 1991, Volume: 39, Issue:4 Topics: Adult; Aged; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Kidney Failure, Chronic; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Renal Dialysis; Simvastatin	1991

Other Studies

27 other study(ies) available for simvastatin and Chronic Kidney Failure

Article	Year
Periadventitial Delivery of Simvastatin-Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula. Journal of the American Heart Association, 2020, 12-15, Volume: 9, Issue:24 Topics: Animals; Anticholesteremic Agents; Arteriovenous Fistula; Chemokine CCL2; Cyclodextrins; Drug Delivery Systems; Fibrosis; Graft Occlusion, Vascular; Hyperplasia; Inflammation; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Models, Animal; Neointima; Simvastatin; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Vascular Remodeling; Veins	2020
Evaluation of Trace Elements in Augmentation of Statin-Induced Cytotoxicity in Uremic Serum-Exposed Human Rhabdomyosarcoma Cells. Toxins, 2018, 01-25, Volume: 10, Issue:2 Topics: Cell Line, Tumor; Cell Survival; Cisplatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Losartan; Metals; Rhabdomyolysis; Rhabdomyosarcoma; Serum; Simvastatin; Superoxide Dismutase; Uremia	2018
Intensive lipid intervention in the post-ENHANCE era. Mayo Clinic proceedings, 2008, Volume: 83, Issue:8 Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; Coronary Disease; Diabetes Complications; Disease Progression; Drug Therapy, Combination; Ezetimibe; Fluorobenzenes; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Kidney Failure, Chronic; Practice Guidelines as Topic; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2008
Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension. American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:1 Topics: Albuminuria; Animals; Antioxidants; Cholesterol; Cyclic N-Oxides; Dietary Fats; Disease Models, Animal; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Kidney Failure, Chronic; Male; Obesity; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Risk Factors; Simvastatin; Spin Labels	2010
Effects of simvastatin on markers of inflammation, oxidative stress and endothelial cell apoptosis in patients on chronic hemodialysis. Journal of atherosclerosis and thrombosis, 2010, Dec-26, Volume: 17, Issue:12 Topics: Apoptosis; Biomarkers; C-Reactive Protein; Case-Control Studies; Endothelial Cells; Humans; Hypolipidemic Agents; Inflammation; Kidney Failure, Chronic; Lipids; Monocytes; Oxidative Stress; Renal Dialysis; Simvastatin	2010
Efficacy and safety of ezetimibe and low-dose simvastatin as primary treatment for dyslipidemia in peritoneal dialysis patients. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2010, Volume: 26 Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, LDL; Drug Combinations; Ezetimibe, Simvastatin Drug Combination; Female; Humans; Hyperlipidemias; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Simvastatin	2010
The SHARP trial: lessons learnt; answers and more questions! International journal of cardiology, 2012, Apr-05, Volume: 156, Issue:1 Topics: Atherosclerosis; Azetidines; Clinical Trials as Topic; Drug Combinations; Ezetimibe, Simvastatin Drug Combination; Humans; Hypolipidemic Agents; Kidney Failure, Chronic; Learning; Simvastatin	2012
In brief: Ezetimibe/simvastatin (Vytorin) in chronic kidney disease. The Medical letter on drugs and therapeutics, 2012, Jan-09, Volume: 54, Issue:1381 Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Drug Combinations; Ezetimibe, Simvastatin Drug Combination; Humans; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Renal Dialysis; Simvastatin	2012
[Nephrology]. Revue medicale suisse, 2012, Jan-11, Volume: 8, Issue:323 Topics: Anticholesteremic Agents; Azathioprine; Azetidines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Kidney Failure, Chronic; Lupus Nephritis; Mycophenolic Acid; Nephrology; Renal Dialysis; Secondary Prevention; Simvastatin; Treatment Outcome	2012
Evaluation of the effects of simvastatin in reduction of panel-reactive antibody (PRA) levels in patients with end-stage renal disease awaiting renal transplantation. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2012, Volume: 23, Issue:2 Topics: Adolescent; Adult; Aged; Antibodies; Female; Histocompatibility Testing; HLA Antigens; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Preoperative Care; Simvastatin; Young Adult	2012
[The SHARP study]. Giornale italiano di cardiologia (2006), 2013, Volume: 14, Issue:2 Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Simvastatin	2013
[Simvastatin and extrinsic coagulation pathway in peritoneally dialyzed patients]. Polskie Archiwum Medycyny Wewnetrznej, 2002, Volume: 107, Issue:6 Topics: Adult; Aged; Blood Coagulation Factors; Factor VII; Factor Xa; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Lipoproteins; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Platelet Aggregation; Simvastatin; Statistics, Nonparametric; Time Factors; von Willebrand Factor	2002
A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients. BMC nephrology, 2002, Nov-14, Volume: 3 Topics: Algorithms; Drug Interactions; Feasibility Studies; Female; Guidelines as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Failure, Chronic; Lipoproteins, LDL; Male; Middle Aged; Patient Care Team; Pharmacy Service, Hospital; Pyridines; Reference Values; Renal Dialysis; Retrospective Studies; Simvastatin; Statistics as Topic	2002
Increased soluble CD40L levels are reduced by long-term simvastatin treatment in peritoneally dialyzed patients. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2004, Volume: 15, Issue:6 Topics: Arteriosclerosis; C-Reactive Protein; CD40 Ligand; E-Selectin; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Inflammation; Kidney Failure, Chronic; Male; Middle Aged; P-Selectin; Peritoneal Dialysis, Continuous Ambulatory; Platelet Aggregation; Simvastatin; Solubility; von Willebrand Factor	2004
Chromosomal damage and atherosclerosis. A protective effect from simvastatin. European journal of pharmacology, 2006, Feb-27, Volume: 532, Issue:3 Topics: Atherosclerosis; Carotid Arteries; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Female; Hemodiafiltration; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Lymphocytes; Male; Middle Aged; Mitotic Index; Simvastatin; Sister Chromatid Exchange; Ultrasonography	2006
Statins inhibit NK cell cytotoxicity by membrane raft depletion rather than inhibition of isoprenylation. Atherosclerosis, 2007, Volume: 191, Issue:2 Topics: Adult; Aged; Cholesterol; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; K562 Cells; Kidney Failure, Chronic; Kidney Transplantation; Killer Cells, Natural; Male; Membrane Microdomains; Middle Aged; Myocardial Ischemia; Pilot Projects; Protein Prenylation; Signal Transduction; Simvastatin	2007
Simvastatin down regulates mRNA expression of RANTES and CCR5 in posttransplant renal recipients with hyperlipidemia. Transplantation proceedings, 2006, Volume: 38, Issue:9 Topics: Adult; Chemokine CCL5; Female; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Kidney Failure, Chronic; Kidney Transplantation; Lipids; Male; Middle Aged; Postoperative Complications; Receptors, CCR5; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin	2006
Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure. The Journal of urology, 2008, Volume: 179, Issue:4 Topics: Animals; Apolipoproteins E; Atherosclerosis; Calcinosis; Disease Models, Animal; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Male; Mice; Oxidative Stress; Simvastatin	2008
Colchicine-induced neuromyopathy in a patient with chronic renal failure: the role of clarithromycin. The Netherlands journal of medicine, 2008, Volume: 66, Issue:5 Topics: Aged; Anti-Bacterial Agents; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Colchicine; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Kidney Failure, Chronic; Male; Neuromuscular Diseases; Risk Factors; Simvastatin; Tubulin Modulators	2008
HMG-CoA reductase inhibitor treatment in renal insufficiency. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:10 Topics: Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Lovastatin; Pravastatin; Rhabdomyolysis; Simvastatin	1996
Potential therapeutic effect of simvastatin on progressive renal failure and nephrotic-range proteinuria caused by renal cholesterol embolism. The American journal of the medical sciences, 2001, Volume: 322, Issue:1 Topics: Anticholesteremic Agents; Creatinine; Disease Progression; Embolism, Cholesterol; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nephrosis; Proteinuria; Simvastatin; Treatment Outcome	2001
Simvastain affects TAFI and thrombomodulin in CAPD patients. Thrombosis and haemostasis, 2001, Volume: 86, Issue:3 Topics: Adult; Anticholesteremic Agents; Biomarkers; Blood Proteins; Carboxypeptidase B2; Cholesterol, LDL; Drug Administration Schedule; Drug Evaluation; Female; Fibrin Fibrinogen Degradation Products; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Lipids; Lipoproteins; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Simvastatin; Thrombomodulin; Thrombophilia	2001
Rhabdomyolysis and acute renal graft impairment in a patient treated with simvastatin, tacrolimus, and fusidic acid. Nephron, 2002, Volume: 90, Issue:2 Topics: Acute Disease; Anti-Bacterial Agents; Drug Interactions; Female; Fusidic Acid; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Middle Aged; Rhabdomyolysis; Simvastatin; Tacrolimus; Treatment Failure	2002
Safety and efficacy of simvastatin in patients undergoing chronic renal dialysis: are we ready to treat hypercholesterolemia? American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 39, Issue:2 Topics: Cardiovascular Diseases; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Renal Dialysis; Simvastatin	2002
[Dyslipidemia in the uremic patient: the therapeutic role played by simvastatin]. La Clinica terapeutica, 1992, Volume: 140, Issue:1 Pt 2 Topics: Aged; Anticholesteremic Agents; Combined Modality Therapy; Drug Evaluation; Female; Humans; Hyperlipidemias; Hypertriglyceridemia; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Renal Dialysis; Simvastatin; Uremia	1992
[The hypotriglyceridemic action of the combination of L-carnitine + simvastatin vs. L-carnitine and vs. simvastatin]. La Clinica terapeutica, 1992, Volume: 140, Issue:1 Pt 2 Topics: Aged; Anticholesteremic Agents; Carnitine; Combined Modality Therapy; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertriglyceridemia; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Renal Dialysis; Simvastatin	1992
Management of non-nephrotic hyperlipidaemia of chronic renal failure with simvastatin. The Medical journal of Australia, 1991, Oct-21, Volume: 155, Issue:8 Topics: Female; Humans; Hyperlipidemias; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Pilot Projects; Simvastatin	1991