Page last updated: 2024-08-23

simvastatin and Cerebral Malaria

simvastatin has been researched along with Cerebral Malaria in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobs, T; Kobbe, R; May, J; Schreiber, N1
Bienvenu, AL; Picot, S1
Gowda, DC; Helmers, AJ; Kain, KC; Liles, WC1

Other Studies

3 other study(ies) available for simvastatin and Cerebral Malaria

ArticleYear
Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Simvastatin; Treatment Outcome

2008
Statins alone are ineffective in cerebral malaria but potentiate artesunate.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Atorvastatin; Disease Models, Animal; Drug Synergism; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Malaria, Cerebral; Malaria, Falciparum; Mice; Neuroprotective Agents; Pravastatin; Pyrroles; Simvastatin

2008
Statins fail to improve outcome in experimental cerebral malaria and potentiate Toll-like receptor-mediated cytokine production by murine macrophages.
    The American journal of tropical medicine and hygiene, 2009, Volume: 81, Issue:4

    Topics: Animals; Antimalarials; Cells, Cultured; Gene Expression Regulation; Humans; Interleukin-6; Macrophages, Peritoneal; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium berghei; Simvastatin; Toll-Like Receptor 2; Toll-Like Receptor 4

2009