Page last updated: 2024-08-23

simvastatin and Carotid Stenosis

simvastatin has been researched along with Carotid Stenosis in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.09)18.2507
2000's16 (72.73)29.6817
2010's4 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kerner, V; Kum, S; Pande, SD; Safdar Husain, F1
Adriano, E; Balestrino, M1
Bauer, I; Bertolotto, M; Dallegri, F; Fabre, M; Galan, K; Lenglet, S; Mach, F; Montecucco, F; Nencioni, A; Palombo, D; Pane, B; Pelli, G; Pende, A; Python, M; Quercioli, A; Spinella, G; Vuilleumier, N1
Andreadou, I; Efentakis, P; Filis, K; Iliodromitis, EK; Karageorgiadi, D; Papapetropoulos, A; Sigala, F; Zampas, P; Zografos, G1
Ayer, R; Chen, W; Jadhav, V; Sugawara, T; Tsubokawa, T; Zhang, JH1
Berthold, HK; Nitschmann, S1
Balduini, W; Buonocore, G; Carloni, S; Girelli, S; Longini, M1
Artese, L; Bajocchi, G; Bei, R; Chiarelli, F; Cipollone, F; Cuccurullo, F; De Cesare, D; Fazia, M; Iezzi, A; Mezzetti, A; Muraro, R; Piattelli, A; Pini, B; Spigonardo, F; Ucchino, S; Zucchelli, M1
Diener, HC1
Audebert, H; Haberl, RL1
Gao, YH; Zhang, M; Zhang, W; Zhang, Y; Zhang, YY; Zhao, YX1
Grond, M1
Bei, R; Chiarelli, F; Cipollone, F; Cuccurullo, C; Cuccurullo, F; De Cesare, D; Di Francesco, A; Fazia, ML; Iezzi, A; Mezzetti, A; Muraro, R; Schmidt, AM; Spigonardo, F; Ucchino, S1
Baba, K; Hayabuchi, N; Imaizumi, T; Ishibashi, M; Kai, H; Kaida, H; Nakaura, H; Tahara, N1
Abe, Y; Furukado, S; Hori, M; Hoshi, T; Hougaku, H; Kitagawa, K; Sakaguchi, M; Yamagami, H1
Baetta, R; Calore, M; Comparato, C; Donetti, E; Fumagalli, R; Paoletti, R; Rossi, A; Soma, MR; Teruzzi, C1
Ballantyne, CM; Jacobson, TA; Schein, JR; Williamson, A1
Dickstein, K; Hegland, O; Larsen, JP1
Badimon, JJ; Chesebro, J; Corti, R; Fayad, ZA; Fuster, V; Helft, G; Mercuri, M; Worthley, SG1
Tsao, P; Yeung, AC1
Asahara, T; Bahlmann, FH; Isner, JM; Kirchmair, R; Losordo, DW; Murayama, T; Nishimura, H; Rittig, K; Silver, M; Walter, DH1
Chen, Z; Detmers, PA; Ehlers, R; Fukutomi, T; Rogers, C; Simon, DI; Wright, SD; Zago, AC1

Reviews

2 review(s) available for simvastatin and Carotid Stenosis

ArticleYear
[Secondary prevention after stroke: healthy life style, oral anticoagulation].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Administration, Oral; Adult; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Blood Coagulation Disorders; Brain Ischemia; Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Clinical Trials as Topic; Contraceptives, Oral; Embolism; Endarterectomy, Carotid; Exercise; Female; Humans; Hypertension; Hypolipidemic Agents; Ischemic Attack, Transient; Life Style; Male; Phenprocoumon; Platelet Aggregation Inhibitors; Recurrence; Simvastatin; Smoking Cessation; Stroke

2003
Maximizing the cost-effectiveness of lipid-lowering therapy.
    Archives of internal medicine, 1998, Oct-12, Volume: 158, Issue:18

    Topics: Anticholesteremic Agents; Atorvastatin; Carotid Stenosis; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Pravastatin; Pyrroles; Simvastatin

1998

Trials

7 trial(s) available for simvastatin and Carotid Stenosis

ArticleYear
[Therapy of familial hypercholesterolemia with or without ezetimibe].
    Der Internist, 2008, Volume: 49, Issue:10

    Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Carotid Stenosis; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Prospective Studies; Simvastatin

2008
Suppression of the functionally coupled cyclooxygenase-2/prostaglandin E synthase as a basis of simvastatin-dependent plaque stabilization in humans.
    Circulation, 2003, Mar-25, Volume: 107, Issue:11

    Topics: Aged; Carotid Stenosis; Cell Movement; Cells, Cultured; Combined Modality Therapy; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Extracellular Matrix; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Intramolecular Oxidoreductases; Isoenzymes; Macrophage Activation; Macrophages; Male; Matrix Metalloproteinases; Membrane Proteins; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Simvastatin; T-Lymphocytes

2003
[Study of diagnostic criteria of intima-media thickening and effects of drugs on peripheral arteries].
    Zhonghua yi xue za zhi, 2004, Aug-02, Volume: 84, Issue:15

    Topics: Adult; Aged; Anticholesteremic Agents; Aorta, Thoracic; Arteriosclerosis; Captopril; Carotid Arteries; Carotid Stenosis; Female; Femoral Artery; Humans; Male; Middle Aged; Reference Standards; Simvastatin; Tunica Intima; Tunica Media; Ultrasonography

2004
Suppression of RAGE as a basis of simvastatin-dependent plaque stabilization in type 2 diabetes.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:12

    Topics: Aged; Anticholesteremic Agents; Carotid Stenosis; Cells, Cultured; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glucose; Glycation End Products, Advanced; Humans; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; NF-kappa B; Peroxidase; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Simvastatin

2006
Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography.
    Journal of the American College of Cardiology, 2006, Nov-07, Volume: 48, Issue:9

    Topics: Aged; Aorta, Thoracic; Atherosclerosis; Carotid Stenosis; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Inflammation; Male; Middle Aged; Positron-Emission Tomography; Prospective Studies; Simvastatin

2006
Statin therapy increases carotid plaque echogenicity in hypercholesterolemic patients.
    Ultrasound in medicine & biology, 2008, Volume: 34, Issue:9

    Topics: Aged; Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Stenosis; Cholesterol; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Interleukin-18; Interleukin-6; Male; Middle Aged; Pravastatin; Probability; Prospective Studies; Pyrroles; Simvastatin; Triglycerides; Tunica Intima; Ultrasonography

2008
Effects of lipid-lowering by simvastatin on human atherosclerotic lesions: a longitudinal study by high-resolution, noninvasive magnetic resonance imaging.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Aorta; Aortic Diseases; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Cholesterol; Cholesterol, LDL; Humans; Hypolipidemic Agents; Longitudinal Studies; Magnetic Resonance Imaging; Remission Induction; Simvastatin; Treatment Outcome; Vascular Patency

2001

Other Studies

13 other study(ies) available for simvastatin and Carotid Stenosis

ArticleYear
Complete resolution of extensive thrombosis of atheromatous non-aneurysmal descending aorta and pulmonary embolism with warfarin therapy.
    BMJ case reports, 2018, Apr-27, Volume: 2018

    Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Brain; Carotid Stenosis; Drug Therapy, Combination; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Middle Aged; Plaque, Atherosclerotic; Pulmonary Embolism; Simvastatin; Stroke; Warfarin

2018
Statin-induced myopathy prevented by creatine administration.
    BMJ case reports, 2018, Aug-27, Volume: 2018

    Topics: Aged; Amaurosis Fugax; Anticholesteremic Agents; Carotid Stenosis; Cholesterol, LDL; Creatine; Drug Therapy, Combination; Ezetimibe; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myalgia; Pyrimidines; Simvastatin; Treatment Outcome

2018
Statin treatment is associated with reduction in serum levels of receptor activator of NF-κB ligand and neutrophil activation in patients with severe carotid stenosis.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Aged; Atherosclerosis; Atorvastatin; Carotid Stenosis; Cohort Studies; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinase 9; Middle Aged; Neutrophil Activation; Neutrophils; NF-kappa B; Osteopontin; Osteoprotegerin; Pyrimidines; Pyrroles; RANK Ligand; Risk Factors; RNA, Messenger; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2014
Reciprocal regulation of eNOS, H
    Redox biology, 2017, Volume: 12

    Topics: Aged; Aged, 80 and over; Carotid Stenosis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Female; Heme Oxygenase-1; Humans; Hydrogen Sulfide; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; NADPH Oxidase 4; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Plaque, Atherosclerotic; Prospective Studies; Proto-Oncogene Proteins c-akt; Simvastatin

2017
Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase.
    Journal of neuroscience research, 2008, Volume: 86, Issue:16

    Topics: Androstadienes; Animals; Carotid Stenosis; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Simvastatin; Subarachnoid Hemorrhage; Up-Regulation; Vasospasm, Intracranial; Wortmannin

2008
Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation.
    Experimental neurology, 2009, Volume: 220, Issue:1

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Brain; Brain Infarction; Carotid Stenosis; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Simvastatin; Up-Regulation

2009
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Atrial Fibrillation; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Clinical Trials as Topic; Diabetes Complications; Diuretics; Doxazosin; Female; Fibrinolytic Agents; Hormone Replacement Therapy; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Life Style; Losartan; Male; Neurology; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors; Simvastatin; Smoking; Societies, Medical; Stroke

2003
[Guidelines given by the DSG and DGN concerning stroke therapy--new therapeutic aspects].
    Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95 Suppl 6

    Topics: Aged; Antihypertensive Agents; Aspirin; Carotid Stenosis; Cerebral Infarction; Combined Modality Therapy; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Secondary Prevention; Simvastatin

2006
Proapoptotic effect of atorvastatin on stimulated rabbit smooth muscle cells.
    Pharmacological research, 1997, Volume: 36, Issue:2

    Topics: Animals; Apoptosis; Atorvastatin; Carotid Stenosis; Cell Division; Cells, Cultured; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Muscle, Smooth, Vascular; Pravastatin; Pyrroles; Rabbits; Simvastatin

1997
Effect of simvastatin in preventing progression of carotid artery stenosis.
    The American journal of cardiology, 2001, Mar-01, Volume: 87, Issue:5

    Topics: Aged; Carotid Artery, Internal; Carotid Stenosis; Disease Progression; Female; Humans; Male; Risk Factors; Simvastatin; Stroke

2001
Statin therapy: beyond cholesterol lowering and antiinflammatory effects.
    Circulation, 2002, Jun-25, Volume: 105, Issue:25

    Topics: Animals; Anti-Inflammatory Agents; Carotid Stenosis; Cell Movement; Coronary Artery Disease; Endothelium, Vascular; Hematopoietic Stem Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Rats; Simvastatin

2002
Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells.
    Circulation, 2002, Jun-25, Volume: 105, Issue:25

    Topics: Angioplasty, Balloon; Animals; Arterial Occlusive Diseases; Bone Marrow Transplantation; Carotid Stenosis; Cell Adhesion; Cell Division; Cell Movement; Cells, Cultured; Endothelium, Vascular; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrins; Kinetics; Male; Mice; Rats; Rats, Sprague-Dawley; Simvastatin

2002
Simvastatin reduces neointimal thickening in low-density lipoprotein receptor-deficient mice after experimental angioplasty without changing plasma lipids.
    Circulation, 2002, Jul-02, Volume: 106, Issue:1

    Topics: Angioplasty; Animals; Anti-Inflammatory Agents; Apoptosis; Carotid Stenosis; Cell Division; Cell Movement; Graft Occlusion, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Leukocytes; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; Simvastatin

2002