simvastatin has been researched along with Cardiotoxicity in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bjørnstad, R; Herfindal, L; Knudsen, KS; Reiten, IN; Schjøtt, J | 1 |
| Belvedere, R; Franceschelli, S; Marzocco, S; Pecoraro, M; Petrella, A; Popolo, A | 1 |
| El-Abhar, HS; Muhammad, RN; Sallam, N | 1 |
| Cross, MJ; Sidaway, JE; Wilkinson, EL | 1 |
| Bonifacio, A; Bouitbir, J; Krähenbühl, S; Mityko, IS; Mullen, PJ; Navegantes, LC | 1 |
5 other study(ies) available for simvastatin and Cardiotoxicity
| Article | Year |
|---|---|
A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect.
Topics: Animals; Cardiotoxicity; Doxorubicin; Liposomes; Male; Neoplasms; Reactive Oxygen Species; Simvastatin; Zebrafish | 2022 |
Simvastatin Reduces Doxorubicin-Induced Cardiotoxicity: Effects beyond Its Antioxidant Activity.
Topics: Antioxidants; Apoptosis; Calcium; Cardiotoxicity; Connexin 43; Doxorubicin; Humans; Myocytes, Cardiac; Simvastatin | 2023 |
Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin.
Topics: Animals; Antimetabolites, Antineoplastic; Cardiotonic Agents; Cardiotoxicity; Endothelin-1; Enzyme Activation; Fluorouracil; Male; MAP Kinase Signaling System; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Simvastatin | 2020 |
Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
Topics: Antibiotics, Antineoplastic; Capillary Permeability; Cardiotoxicity; Cells, Cultured; Coronary Vessels; Cytoprotection; Dose-Response Relationship, Drug; Doxorubicin; Endothelial Cells; Enzyme Activation; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mitogen-Activated Protein Kinase 7; Protein Prenylation; Protein Transport; Quinolines; RNA Interference; Rosuvastatin Calcium; Signal Transduction; Simvastatin; Tight Junctions; Transfection; Zonula Occludens-1 Protein | 2018 |
Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiotoxicity; Cell Line; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Energy Metabolism; Enzyme Activation; Forkhead Box Protein O3; Forkhead Transcription Factors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria, Heart; Muscle Proteins; Myocytes, Cardiac; Phosphorylation; Rats; Simvastatin; SKP Cullin F-Box Protein Ligases; Time Factors; Up-Regulation | 2016 |