simvastatin has been researched along with Cardiac Remodeling, Ventricular in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (56.52) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, K; Kyo, L; Marunouchi, T; Namiki, S; Takahashi, K; Tanonaka, K; Uchida, M; Yano, E | 1 |
| Chan, P; Chen, X; Cheng, Y; Duan, Y; Kuang, Y; Li, H; Liu, J; Liu, Z; Shen, Y; Tomlinson, B; Wang, X; Wang, Y; Yu, Z; Zhang, L; Zhang, Q; Zhang, Y; Zhao, Z; Zhuang, T | 1 |
| Alves, CMR; Berwanger, O; Bianco, HT; Caixeta, A; Carvalho, ACC; Damiani, LP; Fonseca, FAH; Fonseca, HA; França, CN; Izar, MC; Klassen, A; Maugeri, IML; Moreira, FT; Pinto, IM; Soriano Lopes, A; Szarf, G; Tavares, MFM | 1 |
| Adams, ME; Bible, KL; Froehner, SC; Kim, MJ; Regnier, M; Whitehead, NP | 1 |
| Agmadova, ZM; Kallaeva, AN | 1 |
| Adamcova, M; Krajcirovicova, K; Matuskova, J; Paulis, L; Pechanova, O; Pelouch, V; Simko, F | 1 |
| Chang, G; Liu, J; Liu, L; Qin, S; Sun, G; Xiao, X; Zhang, D | 1 |
| DeFranco, A; Emelyanova, L; Holmuhamedov, A; Holmuhamedov, E; Jahangir, A; Kress, D; Negmadjanov, U; Rizvi, F; Ross, G; Shi, Y; Siddiqui, R; Tajik, AJ | 1 |
| Almeida, MR; Almeida, TI; Barauna, VG; Davel, AP; Fernandes, GJ; Garcia, JA; Magalhães, SF; Santos, L; Soares, EA | 1 |
| Ciaccio, EJ | 1 |
| Chen, LS; Chen, PS; Fishbein, MC; Lee, YT; Lin, SF; Liu, YB; Merz, CN; Pak, HN | 1 |
| Adamcova, M; Bednarova, K; Krajcirovicova, K; Mullerova, M; Paulis, L; Pechanova, O; Pelouch, V; Simko, F | 1 |
| Cheng, LX; Dang, SY; Gao, W; He, CR; Sheng, FQ; Wang, CQ; Wang, W; Xu, R; Zeng, QT | 1 |
| Anegawa, T; Hirooka, Y; Imaizumi, T; Kai, H; Kajimoto, H; Koga, M; Kudo, H; Mori, T; Takayama, N; Yasuoka, S | 1 |
| Babal, P; Gvozdjakova, A; Krajcirovicova, K; Kucharska, J; Luptak, I; Matuskova, J; Pechanova, O; Simko, F | 1 |
| Coelho, OR; Franchini, KG; Lagosta, VJ; Moreno, H; Nadruz, W | 1 |
| Bezerra, DG; Mandarim-de-Lacerda, CA | 1 |
| Cheng, X; Ge, H; Guo, Z; Li, B; Liao, YH; Liu, Y; Lu, B; Wang, M; Yang, Y; Zhang, J; Zhang, L | 1 |
| Mann, DL; Ramasubbu, K | 1 |
| Brundel, BJ; Burstein, B; Leung, TK; Mitamura, H; Nattel, S; Ogawa, S; Shiroshita-Takeshita, A | 1 |
| Chen, KJ; Guo, Y; Shi, DZ; Yin, HJ | 1 |
| Chen, T; Hui, J; Jiang, B; Jiang, TB; Jiang, WP; Liu, ZH; Song, JP; Yan, JF; Yang, XJ | 1 |
| Chiang, FT; Hsieh, CS; Hsu, KL; Hwang, JJ; Kuo, KT; Lai, LP; Lin, JL; Tsai, CT; Tseng, CD; Tseng, YZ | 1 |
1 trial(s) available for simvastatin and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Effects of four antiplatelet/statin combined strategies on immune and inflammatory responses in patients with acute myocardial infarction undergoing pharmacoinvasive strategy: Design and rationale of the B and T Types of Lymphocytes Evaluation in Acute My
Topics: Adenosine; Anti-Inflammatory Agents; B-Lymphocytes; Biomarkers; Brazil; Clinical Protocols; Clopidogrel; Coronary Angiography; Drug Therapy, Combination; Enzyme-Linked Immunospot Assay; Ezetimibe; Female; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Magnetic Resonance Imaging; Male; Metabolomics; Platelet Aggregation Inhibitors; Proteomics; Research Design; Rosuvastatin Calcium; Simvastatin; ST Elevation Myocardial Infarction; Stroke Volume; T-Lymphocytes; Thrombolytic Therapy; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2017 |
22 other study(ies) available for simvastatin and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Simvastatin attenuates the c-Raf/Erk and calcineurin-NFATc2 pathways via inhibition of Hsp90 activity during the development of heart failure.
Topics: Animals; Calcineurin; Heart Failure; HSP90 Heat-Shock Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Rats; Simvastatin; Ventricular Remodeling | 2023 |
Endothelial Klf2-Foxp1-TGFβ signal mediates the inhibitory effects of simvastatin on maladaptive cardiac remodeling.
Topics: Animals; Anticholesteremic Agents; Cardiomegaly; Cell Survival; Cells, Cultured; Endothelial Cells; Forkhead Transcription Factors; Heart Failure; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Repressor Proteins; Simvastatin; Transforming Growth Factor beta; Ventricular Remodeling | 2021 |
Simvastatin provides long-term improvement of left ventricular function and prevents cardiac fibrosis in muscular dystrophy.
Topics: Animals; Autonomic Nervous System; Calcium-Binding Proteins; Cardiomyopathies; Disease Models, Animal; Fibrosis; Heart; Heart Rate; Male; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocytes, Cardiac; Phosphorylation; Recovery of Function; Simvastatin; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2019 |
[Special characteristics of progression of myocardial remodeling in patients with various forms of unstable angina].
Topics: Aged; Angina, Unstable; Aspirin; Benzopyrans; Cardiovascular Agents; Disease Progression; Drug Therapy, Combination; Echocardiography, Doppler; Ethanolamines; Female; Heart Failure; Humans; Male; Middle Aged; Nebivolol; Outcome Assessment, Health Care; Perindopril; Platelet Aggregation Inhibitors; Prognosis; Severity of Illness Index; Simvastatin; Time Factors; Ventricular Remodeling | 2014 |
Effects of captopril, spironolactone, and simvastatin on the cardiovascular system of non-diseased Wistar rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Simvastatin; Spironolactone; Ventricular Remodeling | 2015 |
Simvastatin ameliorates ventricular remodeling via the TGF‑β1 signaling pathway in rats following myocardial infarction.
Topics: Animals; Biomarkers; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; MAP Kinase Kinase Kinases; Myocardial Infarction; Rats; Signal Transduction; Simvastatin; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1; Ventricular Function, Left; Ventricular Remodeling | 2016 |
Chamber-specific differences in human cardiac fibroblast proliferation and responsiveness toward simvastatin.
Topics: Acyl Coenzyme A; Cell Proliferation; Cells, Cultured; Cyclins; Fibroblasts; G1 Phase; Heart Atria; Heart Ventricles; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Resting Phase, Cell Cycle; RNA, Messenger; Simvastatin; Ventricular Remodeling | 2016 |
Soy milk versus simvastatin for preventing atherosclerosis and left ventricle remodeling in LDL receptor knockout mice.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Diet; Male; Mice; Mice, Knockout; Receptors, LDL; Simvastatin; Soy Milk; Ventricular Remodeling | 2017 |
Reversal of neural and electrophysiologic remodeling in cardiac tissue.
Topics: Animals; Cholesterol; Electrophysiologic Techniques, Cardiac; Heart Conduction System; Heart Ventricles; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rabbits; Simvastatin; Treatment Outcome; Ventricular Fibrillation; Ventricular Remodeling | 2009 |
Effects of simvastatin on cardiac neural and electrophysiologic remodeling in rabbits with hypercholesterolemia.
Topics: Animals; Cholesterol; Electrophysiologic Techniques, Cardiac; Female; Follow-Up Studies; Heart Conduction System; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Rabbits; Simvastatin; Treatment Outcome; Ventricular Fibrillation; Ventricular Remodeling | 2009 |
Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; Hypertrophy, Left Ventricular; Kidney; Male; Melatonin; Mineralocorticoid Receptor Antagonists; NF-kappa B; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Simvastatin; Spironolactone; Ventricular Remodeling | 2009 |
In rats with myocardial infarction, interference by simvastatin with the TLR4 signal pathway attenuates ventricular remodelling.
Topics: Animals; Anticholesteremic Agents; Dilatation, Pathologic; Endothelium, Vascular; HSP70 Heat-Shock Proteins; Interleukin-6; Male; Myocardial Infarction; Rats; Simvastatin; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2009 |
Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways.
Topics: Animals; Blood Pressure; Cardiomegaly; Carotid Sinus; Cell Enlargement; Cholesterol; Denervation; Extracellular Signal-Regulated MAP Kinases; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Lipoproteins, HDL; Male; Monomeric GTP-Binding Proteins; Myocytes, Cardiac; Rats; Rats, Inbred SHR; rhoA GTP-Binding Protein; Simvastatin; Treatment Outcome; Triglycerides; Ventricular Remodeling | 2011 |
Effect of simvastatin on remodeling of the left ventricle and aorta in L-NAME-induced hypertension.
Topics: Animals; Aorta; Blood Pressure; Body Weight; Coenzymes; DNA; Enzyme Inhibitors; Fibrosis; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Wistar; Simvastatin; Ubiquinone; Ventricular Remodeling | 2004 |
Simvastatin prevents load-induced protein tyrosine nitration in overloaded hearts.
Topics: Animals; Antioxidants; Aorta; Constriction; Coronary Vessels; Enzyme Induction; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Isoenzymes; Male; Membrane Transport Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Oxidative Stress; Phosphoproteins; Pressure; Proteins; Rats; Rats, Wistar; Simvastatin; Tyrosine; Ventricular Remodeling | 2004 |
Beneficial effect of simvastatin and pravastatin treatment on adverse cardiac remodelling and glomeruli loss in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Kidney Glomerulus; Male; Myocardium; Myocytes, Cardiac; Pravastatin; Rats; Rats, Inbred SHR; Simvastatin; Triglycerides; Ventricular Remodeling | 2005 |
Simvastatin regulates myocardial cytokine expression and improves ventricular remodeling in rats after acute myocardial infarction.
Topics: Animals; Blotting, Western; Body Weight; Collagen Type I; Cytokines; Disease Models, Animal; Echocardiography; Female; Gene Expression; Heart; Hemodynamics; Immunohistochemistry; Lipids; Myocardial Infarction; Myocardium; Organ Size; Polymerase Chain Reaction; Rats; Rats, Wistar; Simvastatin; Ventricular Remodeling | 2005 |
The emerging role of statins in the treatment of heart failure.
Topics: Cholesterol, LDL; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Simvastatin; Stroke Volume; Ventricular Remodeling | 2006 |
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure.
Topics: Actins; Animals; Anti-Inflammatory Agents; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Cell Proliferation; Cells, Cultured; Dogs; Fenofibrate; Fibroblasts; Heart Atria; Heart Failure; Heart Ventricles; Hypolipidemic Agents; Models, Animal; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; PPAR alpha; Refractory Period, Electrophysiological; Simvastatin; Tyrosine; Ventricular Remodeling | 2007 |
Effects of Tribuli saponins on ventricular remodeling after myocardial infarction in hyperlipidemic rats.
Topics: Animals; Cardiac Volume; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Male; Myocardial Infarction; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Saponins; Simvastatin; Stroke Volume; Tribulus; Ultrasonography; Ventricular Remodeling | 2007 |
[Effects of simvastatin on the left ventricular expression of transient outward potassium channel in rabbits with experimental heart failure].
Topics: Animals; Disease Models, Animal; Heart Failure; Heart Ventricles; Potassium Channels; Rabbits; Simvastatin; Ventricular Remodeling | 2007 |
Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Cells, Cultured; Fibroblasts; Heart Atria; Humans; Losartan; Muscle Cells; Phosphorylation; rac1 GTP-Binding Protein; Rats; Rats, Wistar; Signal Transduction; Simvastatin; STAT3 Transcription Factor; Ventricular Remodeling | 2008 |