simvastatin has been researched along with Cardiac Failure in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (6.15) | 18.2507 |
| 2000's | 31 (47.69) | 29.6817 |
| 2010's | 23 (35.38) | 24.3611 |
| 2020's | 7 (10.77) | 2.80 |
| Authors | Studies |
|---|---|
| Falcão-Pires, I; Ferrão, D; Ferreira, JP; Leite-Moreira, A; Neves, JS; Rossignol, P; Saraiva, F; Sharma, A; Vasques-Nóvoa, F; Zannad, F | 1 |
| Wang, J; Wang, X; Wen, C; Yan, K | 1 |
| Fujita, K; Kyo, L; Marunouchi, T; Namiki, S; Takahashi, K; Tanonaka, K; Uchida, M; Yano, E | 1 |
| Kopylov, VY | 1 |
| Kang, P; Tang, B; Wang, H; Wang, X; Xu, J; Xuan, L; Zhang, H; Zhu, L | 1 |
| Chan, P; Chen, X; Cheng, Y; Duan, Y; Kuang, Y; Li, H; Liu, J; Liu, Z; Shen, Y; Tomlinson, B; Wang, X; Wang, Y; Yu, Z; Zhang, L; Zhang, Q; Zhang, Y; Zhao, Z; Zhuang, T | 1 |
| Dagda, RK; Moschetti, A; Ryan, RO | 1 |
| Bonsu, KO; Buabeng, KO; Kadirvelu, A; Owusu, IK; Reidpath, DD | 1 |
| Han, L; Liu, ZH; Qi, H; Yang, X; Zhao, C; Zou, C | 1 |
| Shi, J; Wang, L; Zhang, Y | 1 |
| Javaheri, A; Javaheri, S; Rader, DJ | 1 |
| Del Rio, R; Haack, KK; Marcus, NJ; Schultz, HD; Zucker, IH | 1 |
| Huang, XH; Hui, RT; Liu, G; Lu, J; Xu, YL; Zheng, XX | 1 |
| Cha, TJ; Cho, KI; Heo, JH; Jo, GB; Kim, HS; Koo, SH; Lee, JW | 1 |
| Agmadova, ZM; Kallaeva, AN | 1 |
| Bahlmann, E; Boman, K; Chambers, JB; Gerdts, E; Gohlke-Bärwolf, C; Hochholzer, W; Jander, N; Kaufmann, BA; Minners, J; Neumann, FJ; Nienaber, CA; Pedersen, TR; Ray, S; Rossebo, A; Wachtell, K | 1 |
| Chura, OV; Denisova, NN; Fedulaev, YN; Khairetdinova, GA; Logunova, IY; Pinchuk, TV | 1 |
| Bang, CN; Berg, RM; Boman, K; Devereux, RB; Egstrup, K; Gohlke-Baerwolf, C; Greve, AM; Køber, L; Nielsen, OW; Nienaber, CA; Okin, PM; Ray, S; Rossebø, AB; Wachtell, K | 1 |
| Chotenimitkhun, R; D'Agostino, R; Hamilton, CA; Herrington, DM; Hundley, WG; Jordan, JH; Lash, TL; Lawrence, JA; Vasu, S; Yeboah, J | 1 |
| Brunetti, ND; Correale, M; De Gennaro, L; Di Biase, M; Ferraretti, A; Monaco, I; Passero, T; Totaro, A | 1 |
| Chang, YH; Chien, LN; Chuang, MT; Lin, CF; Liu, JC | 1 |
| Cooper, LS; Dunning, A; Fiuzat, M; Fleg, JL; Kelly, JP; Keteyian, SJ; Kitzman, DW; Kraus, WE; Leifer, ES; Mentz, RJ; O'Connor, CM; Pina, IL; Schulte, PJ; Whellan, DJ | 1 |
| Braunwald, E; Cannon, CP; Daga, S; Dalby, AJ; Eisen, A; Goodrich, EL; Im, K; Lukas, MA; O'Donoghue, ML; Spinar, J; Steen, DL; Zhou, J | 1 |
| Desai, A; Resnic, FS | 1 |
| Bérard, A; Blais, L; Dragomir, A; Lalonde, L; Perreault, S; White, M | 1 |
| Faergeman, O; Holme, I; Kastelein, JJ; Larsen, ML; Lindahl, C; Olsson, AG; Pedersen, TR; Strandberg, TE; Tikkanen, MJ | 2 |
| Boffi, L; Capra, A; Corsi, D; Failla, M; Fantini, E; Gentile, G; Giannattasio, C; Maestroni, S; Mancia, G; Meles, E; Scotti, V | 1 |
| Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T | 1 |
| Al'tman, DA; Davydova, EV; Ermak, EM; Pirogov, AL | 1 |
| Nissen, SE; Taylor, AJ | 1 |
| Huang, Y; Lü, XW; Xing, XQ; Xu, J; Zhu, PL | 1 |
| Flett, AS; Godman, BB; Grosso, AM; Moon, JC; Wierzbicki, AS | 1 |
| Adachi, S; Hirao, K; Isobe, M; Ito, H; Maejima, Y; Nobori, K; Ono, Y; Suzuki, J | 1 |
| Komuro, I; Sanada, S | 1 |
| Bonetti, PO; Herrmann, J; Lavi, R; Lerman, A; Lerman, LO; Mannheim, D | 1 |
| Boman, K; Devereux, RB; Egstrup, K; Gohlke-Baerwolf, C; Greve, AM; Kesäniemi, YA; Køber, L; Nienaber, C; Ray, S; Rossebø, AB; Wachtell, K; Willenheimer, R | 1 |
| Leung, AA; van Walraven, C | 1 |
| Chockalingam, A; Deo, SH; Fadel, PJ; Fisher, JP; Kim, A; Vianna, LC; Zimmerman, MC; Zucker, IH | 1 |
| Bates, K; Gaballa, MA; Goldman, S; Ruggeroli, CE | 1 |
| Cornish, KG; Peuler, JD; Pliquett, RU; Zucker, IH | 1 |
| Levenson, D | 1 |
| Hintze, TH; Liao, JK; Mital, S; Ochoa, M; Recchia, FA; Trochu, JN; Xu, X; Zhang, Xp | 1 |
| Bonow, RO; Gheorghiade, M; Kim, RJ; Klein, L; Stone, NJ | 1 |
| Cornish, KG; Gao, L; Li, YL; Liu, D; Schultz, HD; Wang, W; Zucker, IH | 1 |
| Mareev, VIu | 1 |
| Mann, DL; Ramasubbu, K | 1 |
| Elrod, JW; Greer, JJ; Jones, SP; Kakkar, AK; Lefer, DJ; Watson, LJ | 1 |
| Gratsianskiĭ, NA; Masenko, VP; Smetanina, IN; Vaulin, NA | 1 |
| Armitage, J; Bowman, L; Collins, R; Emberson, JR; Ng, LL; Parish, S | 1 |
| Brundel, BJ; Burstein, B; Leung, TK; Mitamura, H; Nattel, S; Ogawa, S; Shiroshita-Takeshita, A | 1 |
| Van Gelder, IC | 1 |
| Azizi, M; Behrens, S; Hashagen, S; Nägele, H | 1 |
| Chen, T; Hui, J; Jiang, B; Jiang, TB; Jiang, WP; Liu, ZH; Song, JP; Yan, JF; Yang, XJ | 1 |
| Behlouli, H; Eisenberg, MJ; Humphries, K; Pilote, L; Rinfret, S; Tu, JV | 1 |
| Rebrov, AP; Tolstov, CN | 1 |
| Gao, L; Wang, W; Zucker, IH | 1 |
| Bodd, E; Hyams, DE; Krüger, K; Roylance, PJ | 1 |
| Hirsch, AT | 1 |
| Faergeman, O; Kjekshus, J; Olsson, AG; Pedersen, TR; Pyörälä, K | 1 |
| Ferguson, JJ | 1 |
| Anker, SD; Coats, AJ; Rauchhaus, M | 1 |
| Dotani, MI; Elnicki, DM; Gibson, CM; Jain, AC | 1 |
| Spinar, J; Spinarová, L; Vítovec, J | 1 |
| Adler, S; Gupta, S; Hintze, TH; Huang, H; Trochu, JN; Xu, X | 1 |
5 review(s) available for simvastatin and Cardiac Failure
| Article | Year |
|---|---|
Effects of lipophilic statins for heart failure: a meta-analysis of 13 randomised controlled trials.
Topics: Atorvastatin; Cholesterol, LDL; Disease Progression; Heart Failure; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Quinolines; Randomized Controlled Trials as Topic; Simvastatin; Stroke Volume; Ventricular Dysfunction, Left | 2014 |
[Study of arterial distensibility in man. Modulating mechanisms, pathological conditions and effects of treatment].
Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Arteries; Arteriosclerosis; Compliance; Diabetes Mellitus; Diuretics; Drug Therapy, Combination; Elasticity; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Risk Factors; Simvastatin; Treatment Outcome | 2003 |
Reviewing the medical literature: five notable articles in general internal medicine from 2010 and 2011.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Azetidines; Cardiomyopathies; Ezetimibe; Female; Heart Failure; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pyrazoles; Pyridones; Recurrence; Risk; Seizures; Simvastatin; Ultrasonography; Warfarin | 2012 |
[Treatment of chronic heart failure. The time of statins?].
Topics: Aged; Animals; Anticholesteremic Agents; Cholesterol; Controlled Clinical Trials as Topic; Costs and Cost Analysis; Disease Models, Animal; Female; Fluorobenzenes; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Male; Prognosis; Pyrimidines; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Time Factors | 2005 |
The endotoxin-lipoprotein hypothesis.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Endotoxins; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipopolysaccharides; Protective Agents; Protein Binding; Simvastatin | 2000 |
16 trial(s) available for simvastatin and Cardiac Failure
| Article | Year |
|---|---|
Simvastatin Combined with Resistance Training Improves Outcomes in Patients with Chronic Heart Failure by Modulating Mitochondrial Membrane Potential and the Janus Kinase/Signal Transducer and Activator of Transcription 3 Signaling Pathways.
Topics: Heart Failure; Humans; Janus Kinases; Membrane Potential, Mitochondrial; Resistance Training; Signal Transduction; Simvastatin; STAT3 Transcription Factor; Stroke Volume; Ventricular Function, Left | 2022 |
Influences of simvastatin on vascular endothelial function of patients with coronary heart disease complicated with congestive heart failure.
Topics: Adult; Aged; Calcitonin Gene-Related Peptide; Coronary Disease; Digoxin; Drug Therapy, Combination; Endothelins; Endothelium, Vascular; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide; Simvastatin | 2013 |
Velocity ratio predicts outcomes in patients with low gradient severe aortic stenosis and preserved EF.
Topics: Aged; Anticholesteremic Agents; Aortic Valve Stenosis; Azetidines; Blood Flow Velocity; Echocardiography; Ezetimibe; Female; Heart Failure; Humans; Male; Prospective Studies; ROC Curve; Simvastatin; Stroke Volume | 2014 |
Resting heart rate and risk of adverse cardiovascular outcomes in asymptomatic aortic stenosis: the SEAS study.
Topics: Aged; Anticholesteremic Agents; Aortic Valve Stenosis; Atrial Fibrillation; Azetidines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Global Health; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Prognosis; Proportional Hazards Models; Prospective Studies; Rest; Simvastatin; Survival Rate; Time Factors | 2015 |
Chronic statin administration may attenuate early anthracycline-associated declines in left ventricular ejection function.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Atorvastatin; Female; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Neoplasms; Pyrroles; Risk Assessment; Risk Factors; Simvastatin; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Left | 2015 |
Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION.
Topics: Aged; Atorvastatin; Exercise Therapy; Exercise Tolerance; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Linear Models; Male; Middle Aged; Oxygen Consumption; Pravastatin; Quality of Life; Simvastatin; Stroke Volume; Treatment Outcome; Walk Test | 2016 |
Congestive heart failure is associated with lipoprotein components in statin-treated patients with coronary heart disease Insights from the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial (IDEAL).
Topics: Aged; Coronary Disease; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Lipoproteins; Male; Middle Aged; Models, Statistical; Predictive Value of Tests; Proportional Hazards Models; Risk; Risk Factors; Simvastatin | 2009 |
Comparative effect of atorvastatin (80 mg) versus simvastatin (20 to 40 mg) in preventing hospitalizations for heart failure in patients with previous myocardial infarction.
Topics: Atorvastatin; Female; Heart Failure; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Prospective Studies; Pyrroles; Simvastatin; Treatment Outcome | 2009 |
Effect of simvastatin vs. rosuvastatin on adiponectin and haemoglobin A1c levels in patients with non-ischaemic chronic heart failure.
Topics: Adiponectin; Aged; C-Reactive Protein; Chronic Disease; Female; Fluorobenzenes; Glycated Hemoglobin; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Male; Middle Aged; Natriuretic Peptide, Brain; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides | 2009 |
[Pleiotropic effects of small dozes simvastatin in patients of senile age with chronic heart failure].
Topics: Aged, 80 and over; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Female; Heart Failure; Humans; Hypolipidemic Agents; Lipids; Male; Simvastatin; Treatment Outcome; Ultrasonography; Vasodilation | 2009 |
Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial.
Topics: Aged; Angiotensin Receptor Antagonists; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Simvastatin; Treatment Outcome; Ventricular Dysfunction, Left | 2011 |
Clinical implications of electrocardiographic left ventricular strain and hypertrophy in asymptomatic patients with aortic stenosis: the Simvastatin and Ezetimibe in Aortic Stenosis study.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Azetidines; Cardiovascular Diseases; Drug Therapy, Combination; Electrocardiography; Ezetimibe; Female; Follow-Up Studies; Heart Failure; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Infarction; Prognosis; Simvastatin; Ventricular Dysfunction, Left | 2012 |
Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure.
Topics: Antioxidants; Biomarkers; Blood Pressure; Cholesterol; Cross-Over Studies; Double-Blind Method; Female; Heart Failure; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Missouri; Muscle, Skeletal; Oxidative Stress; Simvastatin; Stroke Volume; Superoxides; Sympathetic Nervous System; Time Factors; Treatment Outcome | 2012 |
[Short term simvastatin use in patients with heart failure of ischemic origin. Changes of blood lipids, markers of inflammation and left ventricular function].
Topics: Aged; C-Reactive Protein; Cholesterol; Drug Administration Schedule; Echocardiography, Doppler; Female; Follow-Up Studies; Heart Failure; Heart Ventricles; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Myocardial Contraction; Myocardial Infarction; Simvastatin; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Ventricular Function, Left | 2006 |
N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Chi-Square Distribution; Confidence Intervals; Drug Administration Schedule; Female; Follow-Up Studies; Heart Failure; Humans; Hypercholesterolemia; Linear Models; Male; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Probability; Risk Assessment; Severity of Illness Index; Simvastatin; Stroke; Treatment Outcome | 2007 |
The effects of simvastatin on the incidence of heart failure in patients with coronary heart disease.
Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Disease Progression; Heart Failure; Humans; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Retrospective Studies; Simvastatin; Survival Analysis | 1997 |
44 other study(ies) available for simvastatin and Cardiac Failure
| Article | Year |
|---|---|
Fenofibrate and Heart Failure Outcomes in Patients With Type 2 Diabetes: Analysis From ACCORD.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Fenofibrate; Glucose; Heart Failure; Humans; Hypolipidemic Agents; Lipids; Male; Middle Aged; Simvastatin | 2022 |
Simvastatin attenuates the c-Raf/Erk and calcineurin-NFATc2 pathways via inhibition of Hsp90 activity during the development of heart failure.
Topics: Animals; Calcineurin; Heart Failure; HSP90 Heat-Shock Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Rats; Simvastatin; Ventricular Remodeling | 2023 |
Сhanges in the functional state of the epithelium of the proximal renal tubules in patients with the initial stage of chronic heart failure during simvastatin therapy.
Topics: Adult; Diabetes Mellitus, Type 2; Epithelium; Glomerular Filtration Rate; Heart Failure; Humans; Kidney Tubules, Proximal; Middle Aged; Simvastatin; Young Adult | 2020 |
Simvastatin protects heart function and myocardial energy metabolism in pulmonary arterial hypertension induced right heart failure.
Topics: Animals; Energy Metabolism; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pulmonary Arterial Hypertension; Rats; Simvastatin | 2021 |
Endothelial Klf2-Foxp1-TGFβ signal mediates the inhibitory effects of simvastatin on maladaptive cardiac remodeling.
Topics: Animals; Anticholesteremic Agents; Cardiomegaly; Cell Survival; Cells, Cultured; Endothelial Cells; Forkhead Transcription Factors; Heart Failure; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Repressor Proteins; Simvastatin; Transforming Growth Factor beta; Ventricular Remodeling | 2021 |
Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes.
Topics: Animals; Ataxia; Cell Line; Cell Survival; Heart Failure; Humans; Mice; Mitochondria; Mitochondrial Diseases; Muscle Fibers, Skeletal; Muscle Weakness; Muscular Diseases; Nanocomposites; Oxygen Consumption; Simvastatin; Ubiquinone | 2021 |
Statin Treatment and Clinical Outcomes of Heart Failure Among Africans: An Inverse Probability Treatment Weighted Analysis.
Topics: Aged; Atorvastatin; Atrial Fibrillation; Black People; Cardiomyopathy, Dilated; Cardiovascular Diseases; Cause of Death; Comorbidity; Coronary Artery Disease; Diabetes Mellitus; Fatty Acids, Monounsaturated; Fluvastatin; Ghana; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Indoles; Kaplan-Meier Estimate; Longitudinal Studies; Middle Aged; Mortality; Multivariate Analysis; Probability; Proportional Hazards Models; Renal Insufficiency, Chronic; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Treatment Outcome | 2017 |
Simvastatin activates the PPARγ-dependent pathway to prevent left ventricular hypertrophy associated with inhibition of RhoA signaling.
Topics: Animals; Disease Models, Animal; Fibrosis; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Myocardium; PPAR gamma; Rabbits; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Simvastatin; Transcription Factor RelA; Ultrasonography | 2013 |
Statin therapy in heart failure: is it time for a second look?
Topics: Animals; Heart Failure; Male; Respiration; Simvastatin; Sleep Apnea Syndromes | 2014 |
Simvastatin treatment attenuates increased respiratory variability and apnea/hypopnea index in rats with chronic heart failure.
Topics: Animals; Arrhythmias, Cardiac; Carotid Body; Chronic Disease; Disease Models, Animal; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kruppel-Like Transcription Factors; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Respiration; Simvastatin; Sleep Apnea Syndromes | 2014 |
Simvastatin attenuates the oxidative stress, endothelial thrombogenicity and the inducibility of atrial fibrillation in a rat model of ischemic heart failure.
Topics: Animals; Atrial Fibrillation; Blotting, Western; Echocardiography; Heart Failure; Immunohistochemistry; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Simvastatin | 2014 |
[Special characteristics of progression of myocardial remodeling in patients with various forms of unstable angina].
Topics: Aged; Angina, Unstable; Aspirin; Benzopyrans; Cardiovascular Agents; Disease Progression; Drug Therapy, Combination; Echocardiography, Doppler; Ethanolamines; Female; Heart Failure; Humans; Male; Middle Aged; Nebivolol; Outcome Assessment, Health Care; Perindopril; Platelet Aggregation Inhibitors; Prognosis; Severity of Illness Index; Simvastatin; Time Factors; Ventricular Remodeling | 2014 |
Anti-inflammatory effects of simvastatin in patients with chronic heart failure.
Topics: Aged; Anti-Inflammatory Agents; Chronic Disease; Female; Heart Failure; Humans; Inflammation Mediators; Male; Middle Aged; Simvastatin | 2014 |
Lower cardiovascular mortality with atorvastatin and rosuvastatin vs simvastatin: Data from "moderate-intensity" statin users in an observational registry on chronic heart failure (Daunia Heart Failure Registry).
Topics: Aged; Atorvastatin; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Italy; Male; Observational Studies as Topic; Randomized Controlled Trials as Topic; Registries; Rosuvastatin Calcium; Simvastatin; Treatment Outcome; Ventricular Function, Left | 2015 |
Statin use associated with a reduced risk of pneumonia requiring hospitalization in patients with myocardial infarction: a nested case-control study.
Topics: Aged; Atorvastatin; Case-Control Studies; Comorbidity; Diabetes Mellitus; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart Failure; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Incidence; Indoles; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Pneumonia; Protective Factors; Retrospective Studies; Risk Factors; Simvastatin; Stroke; Taiwan | 2016 |
Predictors of Nonuse of a High-Potency Statin After an Acute Coronary Syndrome: Insights From the Stabilization of Plaques Using Darapladib-Thrombolysis in Myocardial Infarction 52 (SOLID-TIMI 52) Trial.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Angina, Unstable; Atorvastatin; Benzaldehydes; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Oximes; Phospholipase A2 Inhibitors; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Renal Insufficiency; Rosuvastatin Calcium; Secondary Prevention; Sex Factors; Simvastatin | 2017 |
Highlights from the 57th annual scientific session of the American College of Cardiology.
Topics: Aortic Valve; Azetidines; Cardiac Catheterization; Catheter Ablation; Coronary Disease; Drug-Eluting Stents; Ezetimibe; Heart Failure; Heart Valve Diseases; Humans; Mitral Valve Insufficiency; Simvastatin; Surgical Instruments | 2008 |
Impact of adherence to statins on chronic heart failure in primary prevention.
Topics: Aged; Atorvastatin; Case-Control Studies; Databases, Factual; Female; Fluorobenzenes; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Lovastatin; Male; Middle Aged; Patient Compliance; Pravastatin; Primary Prevention; Pyrimidines; Pyrroles; Risk; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome | 2008 |
Preliminary observations from preliminary trial results: have we finally had enough?
Topics: Adult; Anticholesteremic Agents; Aortic Valve Stenosis; Azetidines; Cardiovascular Surgical Procedures; Ezetimibe; Heart Failure; Humans; Incidence; Neoplasms; Randomized Controlled Trials as Topic; Reperfusion Injury; Research Design; Simvastatin; Survival Analysis; Treatment Outcome | 2008 |
[Effects of losartan and simvastatin on collagen content, myocardial expression of MMP-2 mRNA, MMP-9 mRNA and TIMP-1 mRNA, TIMP-2 mRNA in pressure overload rat hearts].
Topics: Animals; Gene Expression Regulation; Heart Failure; Losartan; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Rats; Rats, Sprague-Dawley; Simvastatin; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2009 |
Getting better value from the NHS drug budget.
Topics: Angiotensin II Type 1 Receptor Blockers; Budgets; Drugs, Generic; Health Care Reform; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Losartan; Patents as Topic; Practice Patterns, Physicians'; Prescription Drugs; Simvastatin; State Medicine; United Kingdom | 2010 |
Costarring statins with ARBs: going to be a smash hit?
Topics: Angiotensin Receptor Antagonists; Chronic Disease; Drug Therapy, Combination; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Renin-Angiotensin System; Simvastatin; Treatment Outcome | 2011 |
Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect.
Topics: Animals; Diastole; Disease Models, Animal; Female; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypercholesterolemia; Lipids; Microcirculation; Microvessels; Myocardium; Simvastatin; Swine; Tomography, X-Ray Computed; X-Ray Microtomography | 2011 |
Simvastatin restores endothelial NO-mediated vasorelaxation in large arteries after myocardial infarction.
Topics: Animals; Arteries; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Failure; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Reference Values; Simvastatin; Time Factors; Vasodilation; Vasomotor System | 2002 |
Simvastatin normalizes autonomic neural control in experimental heart failure.
Topics: Action Potentials; Animals; Arteries; Autonomic Nervous System; Baroreflex; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Heart Failure; Hemodynamics; Kidney; Male; Norepinephrine; Rabbits; Simvastatin; Sympathetic Nervous System | 2003 |
Statin helps heart failure patients without high cholesterol.
Topics: Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Practice Guidelines as Topic; Simvastatin; Treatment Outcome; United States | 2003 |
Preservation of NO production by statins in the treatment of heart failure.
Topics: Acetylcholine; Animals; Cardiac Pacing, Artificial; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen Consumption; Simvastatin; Vasodilator Agents; Veratrine | 2003 |
Improvement in the function of hibernating myocardium in a patient with heart failure due to coronary artery disease receiving high-dose simvastatin.
Topics: Aged; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Myocardial Contraction; Myocardial Stunning; Simvastatin; Stroke Volume; Ventricular Dysfunction, Left | 2004 |
Simvastatin therapy normalizes sympathetic neural control in experimental heart failure: roles of angiotensin II type 1 receptors and NAD(P)H oxidase.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; NADPH Oxidases; Rabbits; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Tachycardia, Ventricular | 2005 |
The emerging role of statins in the treatment of heart failure.
Topics: Cholesterol, LDL; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Simvastatin; Stroke Volume; Ventricular Remodeling | 2006 |
Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure.
Topics: Animals; Gene Expression Regulation, Enzymologic; Heart Failure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Infarction; Nitric Oxide Synthase Type III; Pulmonary Edema; Severity of Illness Index; Simvastatin; Survival Rate; Ventricular Dysfunction, Left | 2006 |
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure.
Topics: Actins; Animals; Anti-Inflammatory Agents; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Cell Proliferation; Cells, Cultured; Dogs; Fenofibrate; Fibroblasts; Heart Atria; Heart Failure; Heart Ventricles; Hypolipidemic Agents; Models, Animal; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; PPAR alpha; Refractory Period, Electrophysiological; Simvastatin; Tyrosine; Ventricular Remodeling | 2007 |
Rhythm control for atrial fibrillation: non-channel antiarrhythmic drugs are en vogue.
Topics: Amiodarone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antioxidants; Atrial Fibrillation; Heart Conduction System; Heart Failure; Humans; Simvastatin | 2007 |
Rhabdomyolysis after addition of digitoxin to chronic simvastatin and amiodarone therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticholesteremic Agents; Digitoxin; Drug Interactions; Heart Failure; Humans; Male; Middle Aged; Rhabdomyolysis; Risk Factors; Simvastatin | 2007 |
[Effects of simvastatin on the left ventricular expression of transient outward potassium channel in rabbits with experimental heart failure].
Topics: Animals; Disease Models, Animal; Heart Failure; Heart Ventricles; Potassium Channels; Rabbits; Simvastatin; Ventricular Remodeling | 2007 |
Class effects of statins in elderly patients with congestive heart failure: a population-based analysis.
Topics: Aged; Atorvastatin; Female; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Pravastatin; Pyrroles; Simvastatin; Survival Analysis; Treatment Outcome | 2008 |
[Clinico-diagnostic significance of cytokine activation and changes of morphofunctional parameters of the heart in patients with chronic heart failure and possibilities of correction of revealed disturbances with simvastatin].
Topics: Chronic Disease; Cytokines; Female; Heart Failure; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Simvastatin | 2007 |
Simvastatin inhibits central sympathetic outflow in heart failure by a nitric-oxide synthase mechanism.
Topics: Animals; Cells, Cultured; Heart Failure; Heart Rate; Male; Nitric Oxide Synthase; Rabbits; Simvastatin; Sympathetic Fibers, Postganglionic | 2008 |
[Do we kill our cardiac patients with statin therapy? Coenzyme Q10, what do we know?].
Topics: Coenzymes; Heart Failure; Humans; Lovastatin; Simvastatin; Ubiquinone | 1994 |
Clinical trials for prevention of congestive heart failure: from retrospective analysis to prospective hope.
Topics: Anticholesteremic Agents; Coronary Disease; Heart Failure; Humans; Randomized Controlled Trials as Topic; Simvastatin | 1997 |
Meeting highlights. Highlights of the 48th scientific sessions of the American College of Cardiology.
Topics: Abciximab; Alanine; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal; Aspirin; Benzamidines; Biphenyl Compounds; Cardiology; Cardiovascular Agents; Clinical Trials as Topic; Clopidogrel; Combined Modality Therapy; Coronary Disease; Dalteparin; Defibrillators, Implantable; Double-Blind Method; Enalapril; Endothelial Growth Factors; Fatty Acids, Omega-3; Guanidines; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin Fab Fragments; Laser Therapy; Lymphokines; Metoprolol; Multicenter Studies as Topic; Myocardial Revascularization; Platelet Aggregation Inhibitors; Pyrrolidines; Randomized Controlled Trials as Topic; Simvastatin; Sodium-Hydrogen Exchangers; Stents; Sulfones; Thrombolytic Therapy; Ticlopidine; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitamin E | 1999 |
Effect of preoperative statin therapy and cardiac outcomes after coronary artery bypass grafting.
Topics: Aged; Anticholesteremic Agents; Arrhythmias, Cardiac; Atorvastatin; Cause of Death; Coronary Artery Bypass; Coronary Disease; Female; Heart Failure; Heptanoic Acids; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Preoperative Care; Pyrroles; Recurrence; Retrospective Studies; Risk Factors; Simvastatin; Stroke; Treatment Outcome | 2000 |
[Lipids and chronic heart failure].
Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Heart Failure; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Prognosis; Simvastatin | 2000 |
Simvastatin reverses impaired regulation of renal oxygen consumption in congestive heart failure.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Dogs; Endothelium, Vascular; Heart Failure; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Kidney Cortex; Kidney Medulla; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen Consumption; Penicillamine; Ramipril; Simvastatin; Ventricular Function, Left | 2001 |