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simvastatin and Cardiac Diseases

simvastatin has been researched along with Cardiac Diseases in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's5 (29.41)29.6817
2010's9 (52.94)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Cheung, K; McKillip, J; Powers, EM; Powers, JG1
Cross, MJ; Sidaway, JE; Wilkinson, EL1
Cheng, TP; Jian, YP; Li, HM; Li, Y; Liu, C; Liu, X; Ou, JS; Ou, ZJ; Quon, MJ; Shi, MM; Wang, ZP; Wang, ZQ; Xu, YQ; Xu, Z; Zhang, CX; Zhang, W; Zhang, X; Zhou, L1
Demyanets, S; Hohensinner, PJ; Huber, K; Kaun, C; Krychtiuk, KA; Lenz, M; Pentz, R; Stojkovic, S; Thaler, B; Wojta, J; Zuckermann, A1
Christopher-Stine, L; Isackson, PJ; Kitzmiller, JP; Luzum, JA; Ma, C; Nguyen, LM; Ochs-Balcom, HM; Peltier, W; Tarnopolsky, M; Vladutiu, GD; Weisman, M; Wortmann, RL1
Björnsson, E; Enders, F; Lindor, KD; Suwanwalaikorn, S; Treeprasertsuk, S1
Campbell, SM; Godman, B; Gustafsson, LL; Pichetti, S; Sermet, C1
Adabag, S; Ishani, A; Kuskowski, M; McFalls, E; Mithani, S; Slinin, Y1
Bao, MC; Bu, PL; Chen, YG; Gao, HQ; Ji, XP; Li, CB; Li, XX; Zhang, J; Zhang, Y1
Chen, DY; Huang, X1
Faust, M1
Susekov, AV1
Ogrin, C; Perkelvald, A; Winer, N1
Damkier, P; Hallas, J; Korsholm, L; Kristensen, SR; Mickley, H; Poulsen, TS; Vinholt, P1
Bax, JJ; Davignon, J; Dunkelgrun, M; Feringa, HH; Hoeks, SE; Kastelein, JJ; Poldermans, D; Schouten, O; van Domburg, RT; Vidakovic, R; Welten, GM1
Shepherd, J1
Reynolds, TM; Wierzbicki, AS1

Reviews

3 review(s) available for simvastatin and Cardiac Diseases

ArticleYear
A case study of single-pill combination therapy: the ezetimibe/simvastatin combination for treatment of hyperlipidemia.
    ChemMedChem, 2012, Volume: 7, Issue:11

    Topics: Animals; Azetidines; Drug Combinations; Drug Discovery; Ezetimibe, Simvastatin Drug Combination; Heart Diseases; Humans; Hyperlipidemias; Hypolipidemic Agents; Simvastatin

2012
[Practical aspects of "Heart Protection Studies"].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:2

    Topics: Anticholesteremic Agents; Heart Diseases; Humans; Simvastatin; Treatment Outcome

2004
Statin therapy in clinical practice: new developments.
    Current opinion in lipidology, 1995, Volume: 6, Issue:5

    Topics: Angina Pectoris; Anticholesteremic Agents; Cholesterol; Enzyme Inhibitors; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged; Myocardial Infarction; Simvastatin

1995

Trials

2 trial(s) available for simvastatin and Cardiac Diseases

ArticleYear
Simvastatin Treatment Protects Myocardium in Noncoronary Artery Cardiac Surgery by Inhibiting Apoptosis Through miR-15a-5p Targeting.
    Journal of cardiovascular pharmacology, 2018, Volume: 72, Issue:4

    Topics: Adult; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cells, Cultured; China; Drug Administration Schedule; Elective Surgical Procedures; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; MicroRNAs; Middle Aged; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Signal Transduction; Simvastatin; Treatment Outcome

2018
Heart protection study: a focus on diabetic patients.
    Current diabetes reports, 2004, Volume: 4, Issue:3

    Topics: Coronary Disease; Diabetic Angiopathies; Double-Blind Method; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Placebos; Simvastatin; Stroke

2004

Other Studies

12 other study(ies) available for simvastatin and Cardiac Diseases

ArticleYear
Effect of statin use on incidence of eczema and atopic dermatitis: A retrospective cohort study.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:2

    Topics: Adult; Age Factors; Atorvastatin; Dermatitis, Atopic; Dose-Response Relationship, Drug; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Retrospective Studies; Risk Factors; Simvastatin; Young Adult

2021
Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
    Journal of cellular physiology, 2018, Volume: 233, Issue:1

    Topics: Antibiotics, Antineoplastic; Capillary Permeability; Cardiotoxicity; Cells, Cultured; Coronary Vessels; Cytoprotection; Dose-Response Relationship, Drug; Doxorubicin; Endothelial Cells; Enzyme Activation; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mitogen-Activated Protein Kinase 7; Protein Prenylation; Protein Transport; Quinolines; RNA Interference; Rosuvastatin Calcium; Signal Transduction; Simvastatin; Tight Junctions; Transfection; Zonula Occludens-1 Protein

2018
Cardioprotective cytokine interleukin-33 is up-regulated by statins in human cardiac tissue.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cyclohexenes; Cytokines; Diphosphonates; Fibroblasts; Fluvastatin; Gene Expression Regulation; Heart; Heart Diseases; Humans; Interleukin-33; Lovastatin; Mevalonic Acid; Monoterpenes; Myocardium; Myocytes, Cardiac; Pravastatin; Pyridines; rhoA GTP-Binding Protein; Simvastatin; Thiazolidines

2018
Clinical features related to statin-associated muscle symptoms.
    Muscle & nerve, 2019, Volume: 59, Issue:5

    Topics: Aged; Atorvastatin; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Logistic Models; Lovastatin; Male; Medical History Taking; Middle Aged; Muscle Weakness; Muscular Diseases; Myalgia; Obesity; Odds Ratio; Pravastatin; Retrospective Studies; Rhabdomyolysis; Risk Factors; Rosuvastatin Calcium; Simvastatin; Smoking; White People

2019
NAFLD fibrosis score: a prognostic predictor for mortality and liver complications among NAFLD patients.
    World journal of gastroenterology, 2013, Feb-28, Volume: 19, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cause of Death; Chi-Square Distribution; Decision Support Techniques; Fatty Liver; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Liver Cirrhosis; Logistic Models; Male; Metformin; Middle Aged; Minnesota; Multivariate Analysis; Non-alcoholic Fatty Liver Disease; Odds Ratio; Predictive Value of Tests; Prognosis; Risk Factors; Severity of Illness Index; Simvastatin; Time Factors; Young Adult

2013
Multilevel analysis of the influence of patients' and general practitioners' characteristics on patented versus multiple-sourced statin prescribing in France.
    Applied health economics and health policy, 2013, Volume: 11, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Atorvastatin; Diabetes Mellitus; Drug Prescriptions; Drugs, Generic; Fatty Acids, Monounsaturated; Female; Fluorobenzenes; Fluvastatin; France; General Practitioners; Heart Diseases; Heptanoic Acids; Humans; Indoles; Lipid Metabolism Disorders; Male; Middle Aged; Models, Statistical; Practice Patterns, Physicians'; Pravastatin; Prescription Drugs; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2013
Dose-dependent effect of statins on the incidence of acute kidney injury after cardiac surgery.
    The Annals of thoracic surgery, 2011, Volume: 91, Issue:2

    Topics: Acute Kidney Injury; Aged; Cardiac Surgical Procedures; Cohort Studies; Comorbidity; Coronary Artery Bypass; Coronary Disease; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Postoperative Care; Postoperative Complications; Premedication; Renal Dialysis; Simvastatin; Survival Rate

2011
Simvastatin exerts cardioprotective effects and inhibits the activity of Rho-associated protein kinase in rats with metabolic syndrome.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:9

    Topics: Animals; Cardiotonic Agents; Heart; Heart Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Metabolic Syndrome; Mitochondrial Swelling; Myocardium; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Phosphatase 1; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Simvastatin; Vacuoles

2012
[Statin treatment in type 2 diabetes. Is it a must today?].
    MMW Fortschritte der Medizin, 2003, Feb-27, Volume: 145, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Insulin Resistance; Life Style; Middle Aged; Placebos; Pravastatin; Primary Prevention; Risk Factors; Simvastatin

2003
The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:2

    Topics: Aged; Atorvastatin; Blood Platelets; Cholesterol, LDL; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Heart Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Pyrroles; Simvastatin; Ticlopidine; Time Factors; Wound Healing

2005
Effect of statin withdrawal on frequency of cardiac events after vascular surgery.
    The American journal of cardiology, 2007, Jul-15, Volume: 100, Issue:2

    Topics: Aged; Atorvastatin; Electrocardiography; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Myocardial Infarction; Postoperative Complications; Pravastatin; Pyrroles; Simvastatin; Substance Withdrawal Syndrome; Troponin T; Vascular Surgical Procedures

2007
Cholesterol: how low is low enough? Doctors have been slow in getting evidence on lowering cholesterol into practice.
    BMJ (Clinical research ed.), 1999, Feb-20, Volume: 318, Issue:7182

    Topics: Anticholesteremic Agents; Cholesterol; Evidence-Based Medicine; Heart Diseases; Humans; Simvastatin

1999