simvastatin has been researched along with Carcinoma, Ductal, Pancreatic in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Eibl, G; Hines, OJ; Lugea, A; Pandol, SJ; Rozengurt, E; Sinnett-Smith, J; Sun, X; Teper, Y; Waldron, RT; Ye, L | 1 |
| Brunicardi, FC; Creeden, JF; Damoiseaux, R; Erhardt, P; Kalinoski, A; Liu, SH; Markowiak, S; Nemunaitis, J; Sanchez, R; Sutton, JM; Yu, J; Zhang, JT | 1 |
| Bauer, N; Gladkich, J; Gretz, N; Gross, W; Hackert, T; Herr, I; Liu, L; Nwaeburu, CC; Sticht, C; Strobel, O; Yin, L; Yin, Y; Zhao, Z | 1 |
| Chang, J; Cooper, RM; Difronzo, AL; Huang, B; Jeon, CY; Ngor, EW; Pandol, SJ; Wu, BU | 1 |
| Archibugi, L; Capurso, G; Delle Fave, G | 1 |
| Lin, Y; Qin, C; Su, Z; Xian, G; Zhang, Z; Zhao, J | 1 |
| Chang, JI; Huang, BZ; Li, E; Wu, BU; Xiang, AH | 1 |
7 other study(ies) available for simvastatin and Carcinoma, Ductal, Pancreatic
| Article | Year |
|---|---|
Low dosage combination treatment with metformin and simvastatin inhibits obesity-promoted pancreatic cancer development in male KrasG12D mice.
Topics: Adenocarcinoma in Situ; Animals; Carcinoma, Pancreatic Ductal; Female; Male; Mice; Obesity; Pancreatic Neoplasms; Simvastatin | 2023 |
Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy for pancreatic ductal adenocarcinoma.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Digoxin; Drug Combinations; Drug Repositioning; Drug Synergism; High-Throughput Screening Assays; Homeodomain Proteins; Humans; Male; Metformin; Mice; Molecular Targeted Therapy; Pancreatic Neoplasms; Simvastatin; Survivin; Trans-Activators | 2020 |
Simvastatin inhibits sonic hedgehog signaling and stemness features of pancreatic cancer.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chick Embryo; Deoxycytidine; Drug Synergism; Epithelial-Mesenchymal Transition; Gemcitabine; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Neoplasm Transplantation; Neoplastic Stem Cells; Pancreatic Neoplasms; Signal Transduction; Simvastatin | 2018 |
Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer.
Topics: Aged; Carcinoma, Pancreatic Ductal; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Lovastatin; Male; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Proportional Hazards Models; Retrospective Studies; Simvastatin; Survival Rate | 2015 |
Statin Use and Survival in Resectable Pancreatic Cancer: Confounders and Mechanisms.
Topics: Carcinoma, Pancreatic Ductal; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Pancreatic Neoplasms; Simvastatin | 2016 |
Simvastatin attenuates macrophage-mediated gemcitabine resistance of pancreatic ductal adenocarcinoma by regulating the TGF-β1/Gfi-1 axis.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Connective Tissue Growth Factor; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; HMGB1 Protein; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Male; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; RNA Interference; Signal Transduction; Simvastatin; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays | 2017 |
Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; California; Carcinoma, Pancreatic Ductal; Cholesterol, LDL; Deoxycytidine; Drug Prescriptions; Female; Gemcitabine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Pancreatic Neoplasms; Pravastatin; Proportional Hazards Models; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Survival Rate | 2017 |