Page last updated: 2024-08-23

simvastatin and Calcinosis

simvastatin has been researched along with Calcinosis in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (58.33)	29.6817
2010's	10 (41.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cioffi, G; Cramariuc, D; Einarsen, E; Gerdts, E; Mancusi, C; Midtbø, HB; Thomassen, HK	1
Deng, XS; Fullerton, DA; Meng, X; Reece, TB; Venardos, N; Weyant, MJ; Yao, Q	1
Gerdts, E; Gohlke-Bärwolf, C; Jander, N; Minners, J; Pedersen, TR; Ray, S; Wachtell, K	1
Akhyari, P; Assmann, A; Barth, M; Delfs, C; Horstkötter, K; Lichtenberg, A; Munakata, H; Schiffer, F; Zwirnmann, K	1
Cavasin, MA; Chonchol, M; Demos-Davies, KM; Jablonski, K; Keenan, AL; Kendrick, J; Levi, M; Masuda, M; Masuda, R; McKinsey, TA; Miyazaki, M; Miyazaki-Anzai, S; Saunders, SJ	1
Kaleağasıoğlu, F; Olcay, E; Olgaç, V	1
Chen, JS; Chen, JW; Huang, PH; Lai, CF; Lin, CP; Lin, SJ	1
Otto, CM	1
Gu, X; Masters, KS; Monzack, EL	1
Pazianas, M	1
Dumesnil, JG; Pibarot, P	1
Hong, MK; Kang, DH; Kim, JJ; Kim, YH; Lee, CW; Lee, SW; Park, DW; Park, SJ; Park, SW; Song, JK	1
McDaniel, MC; Samady, H	1
Chambers, JB; Viljoen, A; Wierzbicki, AS	1
Apostolakis, E; Koniari, IC; Tsamis, K	1
Blaser, MC; Mirzaei, Z; Simmons, CA; Yip, CY; Zhong, X	1
Brady, TJ; Derfler, K; Haas, M; Hoffmann, U; Kostner, K; Stadler, A	1
Cheng, G; Elmariah, S; Kaplan, FS; Mohler, ER; Wu, B	1
Bellasi, A; Raggi, P	1
Boltan, DD; Bouffard, JP; Khetan, A; Lachar, W; Roberts, WC	1
Bender, K; Carr, JJ; Chandler, ET; Crouse, JR; Davis, DH; Kouba, EO; Menon, L; Morgan, T; Terry, JG	1
Drüeke, TB; Ivanovski, O; Joki, N; Ketteler, M; Lacour, B; Maizel, J; Massy, ZA; Mothu, N; Nguyen-Khoa, T; Nikolov, IG; Szumilak, D; Westenfeld, R	1
Albers, JJ; Brown, BG; Cheung, M; Marino, E; Morse, J; Zhao, XQ	1
Griffin, BP; Lauer, MS; Novaro, GM; Pearce, GL; Sprecher, DL; Tiong, IY	1

Reviews

3 review(s) available for simvastatin and Calcinosis

Article	Year
Natural history of mild and of moderate aortic stenosis-new insights from a large prospective European study. Current problems in cardiology, 2013, Volume: 38, Issue:9 Topics: Anticholesteremic Agents; Aortic Valve; Aortic Valve Stenosis; Azetidines; Calcinosis; Comorbidity; Disease Progression; Drug Therapy, Combination; Ezetimibe; Humans; Hypertension; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Severity of Illness Index; Simvastatin; Treatment Outcome	2013
Aortic stenosis and lipids: does intervention work? Current opinion in cardiology, 2010, Volume: 25, Issue:4 Topics: Anticholesteremic Agents; Aortic Valve Stenosis; Azetidines; Biomarkers, Pharmacological; Calcinosis; Disease Progression; Endothelium, Vascular; Ezetimibe; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Simvastatin; Stress, Physiological	2010
[Atherosclerosis imaging to assess plaque progression]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2005, Volume: 6, Issue:8 Topics: Adult; Aged; Animals; Aortic Diseases; Arteriosclerosis; Calcinosis; Cardiovascular Diseases; Carotid Artery Diseases; Clinical Trials as Topic; Coronary Angiography; Coronary Artery Disease; Cost-Benefit Analysis; Disease Progression; Female; Follow-Up Studies; Humans; Hypolipidemic Agents; Magnetic Resonance Imaging; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin; Time Factors; Tomography, X-Ray Computed	2005

Trials

4 trial(s) available for simvastatin and Calcinosis

Article	Year
Echocardiographic aortic valve calcification and outcomes in women and men with aortic stenosis. Heart (British Cardiac Society), 2017, Volume: 103, Issue:20 Topics: Aged; Anticholesteremic Agents; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Echocardiography; Ezetimibe; Female; Humans; Male; Middle Aged; Risk Factors; Severity of Illness Index; Sex Factors; Simvastatin; Treatment Outcome	2017
Effects of statin treatments on coronary plaques assessed by volumetric virtual histology intravascular ultrasound analysis. JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:7 Topics: Aged; Calcinosis; Coronary Angiography; Coronary Artery Disease; Female; Fibrosis; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Necrosis; Predictive Value of Tests; Pyrimidines; Rosuvastatin Calcium; Severity of Illness Index; Simvastatin; Sulfonamides; Time Factors; Treatment Outcome; Ultrasonography, Interventional; User-Computer Interface	2009
Effects of combined low-density lipoprotein apheresis and aggressive statin therapy on coronary calcified plaque as measured by computed tomography. The American journal of cardiology, 2003, Feb-15, Volume: 91, Issue:4 Topics: Administration, Oral; Aged; Anticholesteremic Agents; Atorvastatin; Blood Component Removal; Calcinosis; Cholesterol, LDL; Combined Modality Therapy; Coronary Artery Disease; Drug Monitoring; Female; Follow-Up Studies; Heptanoic Acids; Heterozygote; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pyrroles; Severity of Illness Index; Simvastatin; Tomography, X-Ray Computed; Treatment Outcome	2003
Effect of simvastatin (80 mg) on coronary and abdominal aortic arterial calcium (from the coronary artery calcification treatment with zocor [CATZ] study). The American journal of cardiology, 2007, Jun-15, Volume: 99, Issue:12 Topics: Adult; Aged; Aorta, Abdominal; Calcinosis; Coronary Vessels; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Simvastatin; Tomography, Spiral Computed	2007

Other Studies

17 other study(ies) available for simvastatin and Calcinosis

Article	Year
Simvastatin reduces the TLR4-induced inflammatory response in human aortic valve interstitial cells. The Journal of surgical research, 2018, Volume: 230 Topics: Adult; Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cardiomyopathy, Dilated; Cells, Cultured; Drug Evaluation, Preclinical; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myofibroblasts; Primary Cell Culture; Simvastatin; Toll-Like Receptor 4	2018
Simvastatin does not diminish the in vivo degeneration of decellularized aortic conduits. Journal of cardiovascular pharmacology, 2014, Volume: 64, Issue:4 Topics: Animals; Aortic Valve; Bioprosthesis; Calcinosis; Calcium; Diet; Disease Models, Animal; Heart Valve Diseases; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Rats, Sprague-Dawley; Rats, Wistar; Simvastatin; Treatment Failure; Ultrasonography	2014
Endoplasmic reticulum stress effector CCAAT/enhancer-binding protein homologous protein (CHOP) regulates chronic kidney disease-induced vascular calcification. Journal of the American Heart Association, 2014, Jun-24, Volume: 3, Issue:3 Topics: Animals; Apolipoproteins E; Atherosclerosis; Azetidines; Calcinosis; Cardiovascular Diseases; Case-Control Studies; Drug Therapy, Combination; Endoplasmic Reticulum; Ezetimibe; Humans; Ketocholesterols; Lipids; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Renal Insufficiency, Chronic; Simvastatin; Transcription Factor CHOP; Vascular Diseases	2014
Statin-induced calcific Achilles tendinopathy in rats: comparison of biomechanical and histopathological effects of simvastatin, atorvastatin and rosuvastatin. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017, Volume: 25, Issue:6 Topics: Achilles Tendon; Aged, 80 and over; Animals; Atorvastatin; Biomechanical Phenomena; Bone Density; Calcinosis; Disease Models, Animal; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Rats, Wistar; Risk Factors; Rosuvastatin Calcium; Rupture, Spontaneous; Simvastatin; Tendinopathy	2017
Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. PloS one, 2015, Volume: 10, Issue:12 Topics: Animals; Arteriosclerosis; Calcinosis; Diet, High-Fat; Down-Regulation; Gene Knockout Techniques; Humans; Male; Mice; Mice, Knockout; NF-kappa B; Oxidative Stress; Receptors, LDL; Receptors, Tumor Necrosis Factor, Type I; Simvastatin; Tumor Necrosis Factor-alpha	2015
Calcific aortic stenosis--time to look more closely at the valve. The New England journal of medicine, 2008, Sep-25, Volume: 359, Issue:13 Topics: Anticholesteremic Agents; Aortic Valve Stenosis; Blood Flow Velocity; Calcinosis; Disease Progression; Drug Therapy, Combination; Humans; Simvastatin; Ultrasonography	2008
Efficacy of simvastatin treatment of valvular interstitial cells varies with the extracellular environment. Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:2 Topics: Animals; Aortic Valve; Calcinosis; Cell Culture Techniques; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Extracellular Matrix; Fibrin; Gels; Heart Valve Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Laminin; Mevalonic Acid; Polystyrenes; rho-Associated Kinases; Simvastatin; Swine; Time Factors; Transforming Growth Factor beta1	2009
Calcific aortic stenosis. The New England journal of medicine, 2009, Jan-01, Volume: 360, Issue:1 Topics: Animals; Anticholesteremic Agents; Aortic Valve Stenosis; Atherosclerosis; Azetidines; Calcinosis; Disease Progression; Ezetimibe; Humans; Models, Biological; Renal Insufficiency, Chronic; Simvastatin	2009
Aortic stenosis: look globally, think globally. JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:4 Topics: Aortic Valve Stenosis; Atherosclerosis; Azetidines; Calcinosis; Disease Progression; Drug Combinations; Echocardiography, Doppler; Ezetimibe, Simvastatin Drug Combination; Hemodynamics; Humans; Hypolipidemic Agents; Myocardial Contraction; Predictive Value of Tests; Risk Assessment; Risk Factors; Simvastatin; Systole; Treatment Outcome; Ventricular Dysfunction, Left	2009
Can statins alter coronary plaque composition assessed by radiofrequency backscatter intravascular ultrasound? JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:7 Topics: Calcinosis; Coronary Artery Disease; Fatty Acids, Monounsaturated; Fibrosis; Fluorobenzenes; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Necrosis; Observer Variation; Predictive Value of Tests; Pyrimidines; Radiography; Rosuvastatin Calcium; Severity of Illness Index; Simvastatin; Sulfonamides; Time Factors; Treatment Outcome; Ultrasonography, Interventional; User-Computer Interface	2009
Simvastatin inhibits aortic valve calcification in hypercholesterolemic rabbits. Interactive cardiovascular and thoracic surgery, 2010, Volume: 11, Issue:3 Topics: Animals; Aortic Valve; Calcinosis; Disease Models, Animal; Heart Valve Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Rabbits; Simvastatin	2010
Inhibition of pathological differentiation of valvular interstitial cells by C-type natriuretic peptide. Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:8 Topics: Animals; Aortic Valve; Calcinosis; Cell Differentiation; Cell Proliferation; Cells, Cultured; Heart Valve Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myofibroblasts; Natriuretic Peptide, C-Type; Osteoblasts; Receptors, Atrial Natriuretic Factor; RNA, Small Interfering; Signal Transduction; Simvastatin; Sus scrofa	2011
Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease. Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:3 Topics: Animals; Aortic Valve; Calcinosis; Cell Differentiation; Cells, Cultured; Cholesterol; Fibroblasts; Heart Valve Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Osteoblasts; Pravastatin; Protein Prenylation; Simvastatin; Stromal Cells; Swine	2005
Fatal and widespread skeletal myopathy confirmed morphologically years after initiation of simvastatin therapy. The American journal of cardiology, 2007, Apr-15, Volume: 99, Issue:8 Topics: Calcinosis; Deglutition Disorders; Dysarthria; Dyspnea; Fatal Outcome; Fibrosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; Muscle Fibers, Skeletal; Muscle Weakness; Muscular Diseases; Necrosis; Simvastatin	2007
Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure. The Journal of urology, 2008, Volume: 179, Issue:4 Topics: Animals; Apolipoproteins E; Atherosclerosis; Calcinosis; Disease Models, Animal; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Male; Mice; Oxidative Stress; Simvastatin	2008
Electron-beam tomography coronary calcium scores are superior to Framingham risk variables for predicting the measured proximal stenosis burden. The American journal of cardiology, 2001, Jul-19, Volume: 88, Issue:2A Topics: Body Burden; Calcinosis; Coronary Angiography; Coronary Disease; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Predictive Value of Tests; Regression Analysis; Risk Factors; Simvastatin; Tomography, X-Ray Computed	2001
Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis. Circulation, 2001, Oct-30, Volume: 104, Issue:18 Topics: Aged; Aortic Valve Stenosis; Atorvastatin; Calcinosis; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Echocardiography; Electrocardiography; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Multivariate Analysis; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin; Treatment Outcome; Triglycerides; Vascular Patency	2001