simvastatin has been researched along with Brain Neoplasms in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Dastghaib, S; Ghavami, S; Mokarram, P; Mostafavi-Pour, Z; Patterson, JB; Samali, A; Sharma, P; Shojaei, S | 1 |
| He, Y; Huang, Y; Jiao, Z; Kang, X; Liu, T; Mo, X; Shi, M; Zheng, Z; Zhong, H | 1 |
| Chen, H; Guo, Q; Han, L; Ju, X; Li, H; Miao, T; Sun, Z; Tao, J; Xu, G; Zhu, Q | 1 |
| Austin, C; Awad, IA; Cao, Y; Gallione, C; Girard, R; Liao, JK; Lightle, R; Marchuk, DA; McDonald, DA; Moore, T; Pytel, P; Rorrer, A; Shenkar, R; Shi, C; Wu, M; Zeineddine, HA; Zhang, L | 1 |
| El-Hamamsy, M; Elwakil, H; Saad, AS; Shawki, MA | 1 |
| Bababeygy, SR; Hou, LC; Polevaya, NV; Prugpichailers, T; Steinman, L; Sun, A; Tse, V; Veeravagu, A; Xiong, A; Youssef, S | 1 |
| Buller, B; Chopp, M; Nallani, A; Santra, K; Santra, M; Santra, S | 1 |
| Bumbasirevic, V; Harhaji-Trajkovic, L; Janjetovic, K; Micic, D; Misirkic, M; Ristic, B; Sumarac-Dumanovic, M; Tovilovic, G; Trajkovic, V; Vilimanovich, U; Vucicevic, L | 1 |
| Altiok, N; Ersoz, M; Karpuz, V; Koyuturk, M | 1 |
1 trial(s) available for simvastatin and Brain Neoplasms
| Article | Year |
|---|---|
A Randomized Controlled Open-Label Pilot Study of Simvastatin Addition to Whole-Brain Radiation Therapy in Patients With Brain Metastases.
Topics: Brain; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Male; Middle Aged; Pilot Projects; Prospective Studies; Quality of Life; Radiation-Sensitizing Agents; Simvastatin | 2016 |
8 other study(ies) available for simvastatin and Brain Neoplasms
| Article | Year |
|---|---|
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Glioblastoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phosphorylation; Signal Transduction; Simvastatin; Temozolomide; Unfolded Protein Response | 2020 |
Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Fenretinide; Glioma; Humans; Lactoferrin; Macrophages; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Oxidative Stress; Simvastatin | 2018 |
LRP1-upregulated nanoparticles for efficiently conquering the blood-brain barrier and targetedly suppressing multifocal and infiltrative brain metastases.
Topics: Animals; Antibiotics, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Cell Line; Doxorubicin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Low Density Lipoprotein Receptor-Related Protein-1; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Nanoparticles; Peptides; Simvastatin | 2019 |
RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain Neoplasms; Disease Models, Animal; Female; Hemangioma, Cavernous, Central Nervous System; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Transgenic; Protein Kinase Inhibitors; rho-Associated Kinases; Simvastatin | 2017 |
HMG-CoA reductase inhibition causes increased necrosis and apoptosis in an in vivo mouse glioblastoma multiforme model.
Topics: Acyl Coenzyme A; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Necrosis; Neoplasms, Experimental; Neovascularization, Physiologic; Simvastatin | 2009 |
Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells.
Topics: Animals; Apoptosis; Brain Neoplasms; Caspase 3; Cell Differentiation; Cell Line, Tumor; Doublecortin Domain Proteins; Doublecortin Protein; Glioma; Humans; Male; Microfilament Proteins; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 8; Neoplastic Stem Cells; Nerve Tissue Proteins; Neuropeptides; Protein Phosphatase 1; Rats; Simvastatin | 2011 |
Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Membrane Proteins; Mice; Microtubule-Associated Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; RNA Interference; Signal Transduction; Simvastatin; TOR Serine-Threonine Kinases; Transfection | 2012 |
Ginkgo biloba extract regulates differentially the cell death induced by hydrogen peroxide and simvastatin.
Topics: Activating Transcription Factor 2; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Ginkgo biloba; Glioma; Humans; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Immunoprecipitation; Neuroglia; Oxidants; Oxidative Stress; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; Simvastatin | 2006 |