Page last updated: 2024-08-23

simvastatin and Brain Hemorrhage, Cerebral

simvastatin has been researched along with Brain Hemorrhage, Cerebral in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's6 (37.50)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Chen, Q; Chen, Z; Feng, H; Hao, N; Li, W; Shi, X; Wu, Y; Zhang, J1
Chen, H; Hu, Y; Qin, X; Wang, M; Wang, S; Wu, J; Wu, T; Wu, Y; Yang, R; Yu, H1
Chen, CC; Chen, HJ; Chen, JS; Liang, CL; Liu, KY; Wang, HK; Wang, KW; Yeh, LR1
Chen, Q; Chen, Z; Feng, H; Feng, Z; He, Z; Tan, Q; Tang, J; Wang, Y; Zhu, G1
Hu, JL; Li, HB; Li, X; Li, YM; Ren, XM; Wang, KX; Wei, W; Zhang, CY1
McLaurin, J; Stefanovic, B; Thomason, LA1
Chen, Q; Chen, Z; Feng, H; Feng, Z; Shi, X; Tan, L; Tan, Q; Tao, Y; Wang, Y; Yuan, Q; Zhang, J; Zhu, G1
Chopp, M; Han, Y; Karki, K; Knight, RA; Ledbetter, KA; Seyfried, DM; Yang, D; Zhang, J1
Han, MK; Lapchak, PA1
Chopp, M; Ding, C; Han, Y; Karki, K; Knight, RA; Seyfried, DM; Yang, D; Zhang, J1
Bu, X; Cheng, P; Guo, X; Jiang, J; Yan, Z1
Chollet, ME; Pérez, J; Tristano, A1
Coull, BM1
Guo, SZ; Kim, WJ; Lee, SR; Lo, EH; Montaner, J; Wang, S; Wang, X1
Buchan, AM; Demchuk, AM; Eliasziw, M; Hill, MD; Kennedy, J; Ryckborst, KJ1
Asplund, K; Jonsson, N1

Reviews

2 review(s) available for simvastatin and Brain Hemorrhage, Cerebral

ArticleYear
Cerebrovascular contributions to Alzheimer's disease pathophysiology and potential therapeutic interventions in mouse models.
    The European journal of neuroscience, 2013, Volume: 37, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Hemorrhage; Cerebrum; Disease Models, Animal; Inositol; Mice; Simvastatin

2013
Statin therapy after acute ischemic stroke in the heart protection study: is the role in recurrent stroke prevention now defined?
    Stroke, 2004, Volume: 35, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Brain Ischemia; Cerebral Hemorrhage; Comorbidity; Coronary Disease; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk; Risk Factors; Simvastatin; Vitamins

2004

Trials

1 trial(s) available for simvastatin and Brain Hemorrhage, Cerebral

ArticleYear
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial.
    The Lancet. Neurology, 2007, Volume: 6, Issue:11

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Ischemic Attack, Transient; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Risk Reduction Behavior; Secondary Prevention; Severity of Illness Index; Simvastatin; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2007

Other Studies

13 other study(ies) available for simvastatin and Brain Hemorrhage, Cerebral

ArticleYear
Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage.
    Current neurovascular research, 2022, Volume: 19, Issue:3

    Topics: Animals; bcl-2-Associated X Protein; Brain Injuries; Cerebral Hemorrhage; Male; Myeloid Cell Leukemia Sequence 1 Protein; Neuroinflammatory Diseases; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Simvastatin

2022
Is statin therapy after ischaemic stroke associated with increased intracerebral hemorrhage? The association may be dependent on intensity of statin therapy.
    International journal of stroke : official journal of the International Stroke Society, 2023, Volume: 18, Issue:8

    Topics: Atorvastatin; Brain Ischemia; Cerebral Hemorrhage; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Stroke; Rosuvastatin Calcium; Simvastatin; Stroke

2023
Simvastatin-Ezetimibe enhances growth factor expression and attenuates neuron loss in the hippocampus in a model of intracerebral hemorrhage.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:4

    Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Drug Therapy, Combination; Ezetimibe; Hippocampus; Intercellular Signaling Peptides and Proteins; Male; Maze Learning; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Simvastatin

2021
Simvastatin accelerates hematoma resolution after intracerebral hemorrhage in a PPARγ-dependent manner.
    Neuropharmacology, 2018, Volume: 128

    Topics: Anilides; Animals; Anticholesteremic Agents; Antigens, CD; Cell Count; Cerebral Hemorrhage; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Hematoma; Male; Microglia; Neurologic Examination; Phagocytosis; PPAR gamma; Protein Transport; Rats; Rats, Sprague-Dawley; Simvastatin; Time Factors

2018
Simvastatin alleviates inflammation and oxidative stress in rats with cerebral hemorrhage through Nrf2-ARE signaling pathway.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:14

    Topics: Animals; Antioxidant Response Elements; Cerebral Hemorrhage; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Interleukin-1beta; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Simvastatin; Toll-Like Receptor 4

2019
Simvastatin Promotes Hematoma Absorption and Reduces Hydrocephalus Following Intraventricular Hemorrhage in Part by Upregulating CD36.
    Translational stroke research, 2017, Volume: 8, Issue:4

    Topics: Animals; Brain; CD11b Antigen; CD36 Antigens; Cell Count; Cerebral Hemorrhage; Disease Models, Animal; Ependyma; Ferritins; Follow-Up Studies; Hematoma; Hydrocephalus; Hypolipidemic Agents; Lateral Ventricles; Magnetic Resonance Imaging; Male; Maze Learning; Microscopy, Electron, Transmission; Neurologic Examination; Neurons; Rats; Rats, Sprague-Dawley; Simvastatin; Up-Regulation

2017
Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage.
    Stroke, 2009, Volume: 40, Issue:10

    Topics: Animals; Apoptosis; Atorvastatin; Biomarkers; Brain; Brain Infarction; Bromodeoxyuridine; Cerebral Hemorrhage; Cytoprotection; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microtubule-Associated Proteins; Nerve Degeneration; Neurogenesis; Neuronal Plasticity; Neuropeptides; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Regeneration; Simvastatin; Treatment Outcome

2009
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin reduces thrombolytic-induced intracerebral hemorrhage in embolized rabbits.
    Brain research, 2009, Dec-15, Volume: 1303

    Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Fibrinolytic Agents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Embolism; Male; Preoperative Care; Rabbits; Rats; Simvastatin; Thrombolytic Therapy; Tissue Plasminogen Activator

2009
Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: magnetic resonance imaging and histological study.
    Journal of neurosurgery, 2011, Volume: 114, Issue:4

    Topics: Animals; Atorvastatin; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Circulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Magnetic Resonance Imaging; Neovascularization, Physiologic; Nerve Regeneration; Pyrroles; Rats; Rats, Wistar; Simvastatin

2011
Enhanced neuroprotective effects of co-administration of G-CSF with simvastatin on intracerebral hemorrhage in rats.
    Turkish neurosurgery, 2012, Volume: 22, Issue:6

    Topics: Animals; Apoptosis; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Drug Combinations; Granulocyte Colony-Stimulating Factor; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Simvastatin

2012
[Bilateral occipital intraparenchymatous hemorrhage].
    Neurologia (Barcelona, Spain), 2003, Volume: 18, Issue:4

    Topics: Cerebral Hemorrhage; Functional Laterality; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Male; Middle Aged; Occipital Lobe; Simvastatin; Tomography, X-Ray Computed

2003
Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes.
    Stroke, 2006, Volume: 37, Issue:7

    Topics: Amides; Animals; Astrocytes; Cells, Cultured; Cerebral Hemorrhage; Drug Evaluation, Preclinical; Enzyme Induction; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuroprotective Agents; Protein Serine-Threonine Kinases; Pyridines; Rats; Recombinant Proteins; rho-Associated Kinases; Signal Transduction; Simvastatin; Stroke

2006
Does pretreatment with statins improve clinical outcome after stroke? A pilot case-referent study.
    Stroke, 2001, Volume: 32, Issue:5

    Topics: Acute Disease; Adult; Age Distribution; Aged; Case-Control Studies; Cerebral Hemorrhage; Comorbidity; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Pilot Projects; Prognosis; Retrospective Studies; Secondary Prevention; Sex Distribution; Simvastatin; Stroke; Sweden; Treatment Outcome

2001