simvastatin has been researched along with Blood Clot in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (24.32) | 18.2507 |
| 2000's | 12 (32.43) | 29.6817 |
| 2010's | 15 (40.54) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Arnaboldi, F; Bitto, N; Colombo, M; Denti, L; Dondossola, D; Gagliano, N; La Mura, V; Latini, R; Liguori, E; Peyvandi, F; Procacci, P; Ristagno, G; Salerno, F; Sartori, P; Tripodi, A | 1 |
| Dong, R; Gao, Y; Liu, S; Ma, G; Su, Y; Zhang, S | 1 |
| Anderson, DC; Boden, WE; Chaitman, BR; Cruz-Flores, S; Goldstein, LB; Grant, S; Kostuk, WJ; Padley, RJ; Sila, CA; Teo, KK; Weintraub, WS | 1 |
| Byrnes, JR; Mackman, N; Owens, AP | 1 |
| Cormode, DP; Farokhzad, OC; Fay, F; Fayad, ZA; Fisher, EA; Hennessy, EJ; Kim, Y; Langer, R; Ma, M; Moore, K; Mulder, WJ; Sanchez-Gaytan, BL; Tang, J | 1 |
| Badimon, L; de la Torre, R; Peña, E; Slevin, M; Vilahur, G | 1 |
| Chichelli, T; Drake, A; Hojnacki, D; Hu, Q; Liu, S; Munschauer, F; Sternberg, D; Sternberg, Z | 1 |
| Barbato, R; Chello, M; Coccia, R; Covino, E; De Marco, F; Di Domenico, F; Lusini, M; Spadaccio, C | 1 |
| Baigent, C; Blackwell, L; Emberson, J; Fellström, B; Haynes, R; Herrington, W; Hooi, LS; Landray, MJ; Levin, A; Massy, ZA; Reith, C; Staplin, N; Tesar, V; Walker, R | 1 |
| Demyanets, S; Domenig, CM; Hofmann, M; Huk, I; Klinger, M; Mittlboeck, M; Nanobachvili, J; Neumayer, C; Piechota-Polanczyk, A; Wojta, J | 1 |
| Banach, M; Bittner, V; Hovingh, GK; Kastelein, JJ; Lip, GY; Mikhailidis, DP; Ray, K; Rysz, J; Sahebkar, A; Serban, C; Undas, A; Ursoniu, S; Watts, GF | 1 |
| Potaczek, DP; Stepien, E; Tracz, W; Undas, A | 1 |
| Coplan, N; Gintautas, J; Gupta, MP; Labana, SS; Polena, S; Shaikh, H; Soffer, D; Zazzali, K | 1 |
| Topór-Madry, R; Tracz, W; Undas, A | 1 |
| Gorkiewicz-Kot, I; Kaczmarek, P; Rzeszutko, M; Skucha, W; Sladek, K; Stepien, E; Tracz, W; Undas, A | 1 |
| Cheng, CF; Cheng, WT; Kikuchi, T; Lian, WS; Lin, H | 1 |
| Karska-Basta, I; Kubicka-Trząska, A; Romanowska-Dixon, B; Undas, A | 1 |
| Chen, KJ; Guo, CY; Huang, Y; Ma, XJ; Shi, DZ; Wu, CF; Xue, M; Yin, HJ | 1 |
| Antoniak, S; Curtiss, LK; Daugherty, A; Dutton, JA; Furie, B; Furie, BC; Hubbard, BK; Johns, DG; Kirchhofer, D; Luyendyk, JP; Mackman, N; Marshall, SM; McDaniel, AL; Moriarty, PM; Nagarajan, S; Owens, AP; Passam, FH; Rudel, L; Temel, RE; Tobias, PS; Wang, J; Williams, JC | 1 |
| Hot, A; Lavocat, F; Lenief, V; Miossec, P | 1 |
| Ahn, JY; Jin, DK; Kim, DS; Koh, KK; Park, GS; Shin, EK; Son, JW | 1 |
| Ahn, JY; Ahn, TH; Choi, IS; Han, SH; Kim, DS; Koh, KK; Park, GS; Shin, EK; Son, JW | 1 |
| Ferrara, DE; Pierangeli, SS | 1 |
| Celinska-Löwenhoff, M; Löwenhoff, T; Szczeklik, A; Undas, A | 1 |
| Gurbanov, E; Shiliang, X | 1 |
| Anselmi, A; Chello, M; Covino, E; Di Sciascio, G; Lusini, M; Patti, G; Spadaccio, C | 1 |
| Auteri, A; Bruni, F; Ciani, F; Ghezzi, A; Palazzuoli, A; Pasqui, AL; Pastorelli, M; Pontani, A; Puccetti, L | 1 |
| Grau, E; Pastor, E; Perella, M | 1 |
| Rosenson, RS; Tangney, CC | 1 |
| Sinzinger, H | 1 |
| Mann, J; Thomas, M | 1 |
| Alfon, J; Badimon, L; Pueyo Palazon, C; Royo, T | 1 |
| Ikeda, U; Shimada, K; Shimpo, M | 1 |
| Heckbert, SR; Weiss, NS | 1 |
| Crook, MA; Jackson, G; Reynolds, TM; Wierzbicki, AS | 1 |
| Bonaa, KH; Hansen, JB; Nilsen, H; Nordoy, A; Sandset, PM | 1 |
5 review(s) available for simvastatin and Blood Clot
| Article | Year |
|---|---|
Hyperlipidemia, tissue factor, coagulation, and simvastatin.
Topics: Animals; Blood Coagulation; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Simvastatin; Thromboplastin; Thrombosis | 2014 |
The impact of statin therapy on plasma levels of von Willebrand factor antigen. Systematic review and meta-analysis of randomised placebo-controlled trials.
Topics: Adult; Aged; Antigens; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Rosuvastatin Calcium; Simvastatin; Thrombosis; von Willebrand Factor; Young Adult | 2016 |
The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension.
Topics: Apoptosis; Dichloroacetic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Lovastatin; MAP Kinase Kinase Kinase 5; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Neoplasm Proteins; Pancreatic Elastase; PPAR gamma; Protein Serine-Threonine Kinases; Pulmonary Circulation; Receptor, Bradykinin B2; rho-Associated Kinases; Simvastatin; Survivin; Thrombosis; Vasoconstriction | 2006 |
Antiatherothrombotic properties of statins: implications for cardiovascular event reduction.
Topics: Animals; Antithrombins; Cardiovascular Diseases; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Endothelium, Vascular; Fibrinogen; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Inflammation; Lovastatin; Muscle, Smooth, Vascular; Platelet Aggregation; Pravastatin; Simvastatin; Thromboplastin; Thrombosis | 1998 |
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis | 1998 |
10 trial(s) available for simvastatin and Blood Clot
| Article | Year |
|---|---|
Extended-release niacin therapy and risk of ischemic stroke in patients with cardiovascular disease: the Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcome (AIM-HIGH) trial.
Topics: Aged; Atherosclerosis; Brain Ischemia; Delayed-Action Preparations; Female; Follow-Up Studies; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Male; Metabolic Syndrome; Middle Aged; Niacin; Simvastatin; Stroke; Thrombosis; Triglycerides | 2013 |
Quantitative and qualitative pleiotropic differences between Simvastatin single and Vytorin combination therapy in hypercholesterolemic subjects.
Topics: Adult; Azetidines; C-Reactive Protein; Cross-Over Studies; Cross-Sectional Studies; Drug Combinations; Ezetimibe, Simvastatin Drug Combination; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Hypercholesterolemia; Immune System; Leukocytes, Mononuclear; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Platelet Adhesiveness; Simvastatin; Thrombosis | 2013 |
The effect of lowering LDL cholesterol on vascular access patency: post hoc analysis of the Study of Heart and Renal Protection.
Topics: Aged; Anticholesteremic Agents; Azetidines; Catheterization; Cholesterol, LDL; Device Removal; Drug Therapy, Combination; Ezetimibe; Female; Humans; Male; Middle Aged; Renal Dialysis; Renal Insufficiency, Chronic; Reoperation; Simvastatin; Thrombosis; Vascular Access Devices; Vascular Patency | 2014 |
Tissue factor +5466A>G polymorphism determines thrombin formation following vascular injury and thrombin-lowering effects of simvastatin in patients with ischemic heart disease.
Topics: Antithrombin III; Bleeding Time; Fibrinolytic Agents; Gene Frequency; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Linear Models; Male; Middle Aged; Myocardial Ischemia; Peptide Fragments; Peptide Hydrolases; Polymorphism, Genetic; Prothrombin; Risk Assessment; Risk Factors; Simvastatin; Thrombin; Thromboplastin; Thrombosis; Treatment Outcome | 2009 |
Platelet aggregation inhibition in patients receiving statins either fully or partially metabolized by CYP3A4.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Clopidogrel; Cytochrome P-450 CYP3A; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Simvastatin; Thrombosis; Ticlopidine | 2008 |
Simvastatin increases clot permeability and susceptibility to lysis in patients with LDL cholesterol below 3.4 mmol/l.
Topics: Adult; Anticholesteremic Agents; C-Reactive Protein; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Fibrinolysis; Humans; Hypercholesterolemia; Male; Middle Aged; Permeability; Simvastatin; Thrombosis; Treatment Outcome; Triglycerides | 2009 |
Fibrin clot properties are altered in patients with chronic obstructive pulmonary disease. Beneficial effects of simvastatin treatment.
Topics: Aged; Blood Coagulation; Case-Control Studies; Female; Fibrin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Microscopy, Electron, Scanning; Middle Aged; Pulmonary Disease, Chronic Obstructive; Simvastatin; Thrombosis | 2009 |
Effects of statin on plaque stability and thrombogenicity in hypercholesterolemic patients with coronary artery disease.
Topics: Apolipoproteins; Coronary Disease; Female; Focal Adhesions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Male; Matrix Metalloproteinase 9; Middle Aged; Simvastatin; Thrombosis; Triglycerides | 2003 |
Statins, fenofibrate, and quinapril increase clot permeability and enhance fibrinolysis in patients with coronary artery disease.
Topics: Aged; Atorvastatin; Coronary Artery Disease; Fenofibrate; Fibrinolysis; Genotype; Heptanoic Acids; Humans; Male; Permeability; Pyrroles; Quinapril; Simvastatin; Tetrahydroisoquinolines; Thrombin; Thrombosis | 2006 |
Effect of omega-3 fatty acids and simvastatin on hemostatic risk factors and postprandial hyperlipemia in patients with combined hyperlipemia.
Topics: Adult; Blood Glucose; Dietary Fats; Double-Blind Method; Eating; Factor VIIa; Fatty Acids, Omega-3; Female; Hemostasis; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Risk Factors; Simvastatin; Thrombosis | 2000 |
22 other study(ies) available for simvastatin and Blood Clot
| Article | Year |
|---|---|
Simvastatin Prevents Liver Microthrombosis and Sepsis Induced Coagulopathy in a Rat Model of Endotoxemia.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Endotoxemia; Fibrin; Hemostatics; Lipopolysaccharides; Liver Diseases; Male; Necrosis; Rats; Rats, Wistar; Sepsis; Simvastatin; Thrombosis; von Willebrand Factor | 2022 |
Simvastatin reverses multiple myeloma serum-induced prothrombotic phenotype in endothelial cells via ERK 1/2 signalling pathway.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Human Umbilical Vein Endothelial Cells; Humans; Hypolipidemic Agents; Male; MAP Kinase Signaling System; Middle Aged; Multiple Myeloma; Phosphatidylserines; Protein C; Simvastatin; Thrombin; Thromboplastin; Thrombosis | 2018 |
Single step reconstitution of multifunctional high-density lipoprotein-derived nanomaterials using microfluidics.
Topics: Animals; Cholesterol; Computer Simulation; Drug Carriers; Ferric Compounds; Fluorescent Dyes; Gold; Lipoproteins, HDL; Liver; Macrophages; Magnetic Resonance Imaging; Mice; Microfluidics; Microscopy, Fluorescence; Models, Theoretical; Nanoparticles; Nanostructures; Quantum Dots; Simvastatin; Thrombosis; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha | 2013 |
Monomerization of C-reactive protein requires glycoprotein IIb-IIIa activation: pentraxins and platelet deposition.
Topics: Annexin A5; Blood Platelets; C-Reactive Protein; Cell Adhesion; Healthy Volunteers; Humans; Immunity, Innate; Inflammation; Nerve Tissue Proteins; Phospholipids; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Isoforms; Serum Amyloid P-Component; Shear Strength; Simvastatin; Thrombosis | 2013 |
Simvastatin attenuates the endothelial pro-thrombotic shift in saphenous vein grafts induced by Advanced glycation endproducts.
Topics: Aged; Blood Glucose; Endothelial Cells; Female; Humans; Male; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Saphenous Vein; Simvastatin; Thrombosis | 2014 |
The Influence of Simvastatin on NGAL, Matrix Metalloproteinases and Their Tissue Inhibitors in Human Intraluminal Thrombus and Abdominal Aortic Aneurysm Tissue.
Topics: Acute-Phase Proteins; Aged; Aortic Aneurysm, Abdominal; Female; Humans; Lipocalin-2; Lipocalins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Proto-Oncogene Proteins; RNA, Messenger; Simvastatin; Thrombosis; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2015 |
Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Fibrosis; Granulocyte Colony-Stimulating Factor; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocarditis; Simvastatin; Thrombosis; Tirofiban; Tyrosine | 2011 |
Altered fibrin clot properties in patients with retinal vein occlusion.
Topics: C-Reactive Protein; Coronary Artery Disease; Female; Fenofibrate; Fibrin; Fibrinolysis; Heptanoic Acids; Homocysteine; Humans; Hypersensitivity, Immediate; Laser Coagulation; Lipoprotein(a); Male; Pyrroles; Retinal Vein; Retinal Vein Occlusion; Simvastatin; Tetrahydroisoquinolines; Thrombosis; Venous Thromboembolism; Venous Thrombosis | 2011 |
Effect of Chinese drugs for activating blood circulation and detoxifying on indices of thrombosis, inflammatory reaction, and tissue damage in a rabbit model of toxin-heat and blood stasis syndrome.
Topics: Analysis of Variance; Animals; Atherosclerosis; Blood Circulation; Disease Models, Animal; Drugs, Chinese Herbal; Endothelium, Vascular; Immunohistochemistry; Inflammation; Male; Rabbits; Random Allocation; Sensitivity and Specificity; Simvastatin; Systemic Inflammatory Response Syndrome; Thrombosis | 2013 |
Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin.
Topics: Animals; Anticholesteremic Agents; Blood Coagulation; Cells, Cultured; Chlorocebus aethiops; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Mice; Monocytes; Receptors, LDL; Simvastatin; Thromboplastin; Thrombosis; Toll-Like Receptor 4; Toll-Like Receptor 6 | 2012 |
Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Anticholesteremic Agents; Antirheumatic Agents; Atherosclerosis; Drug Interactions; Endothelial Cells; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Infliximab; Interleukin-17; Interleukin-6; Interleukin-8; Platelet Aggregation; Simvastatin; Thrombosis; Tumor Necrosis Factor-alpha | 2013 |
Comparative effects of diet and simvastatin on markers of thrombogenicity in patients with coronary artery disease.
Topics: Anticholesteremic Agents; Antineoplastic Agents; Apolipoproteins; Biomarkers; C-Reactive Protein; Coronary Disease; Female; Fibrinogen; Hemostatics; Humans; Hyperlipidemias; Lipoproteins; Male; Matrix Metalloproteinase 9; Middle Aged; Placebo Effect; Protease Inhibitors; Simvastatin; Thromboplastin; Thrombosis; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2003 |
More on: fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells.
Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Contraindications; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fibrinolytic Agents; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; NF-kappa B; Pyridines; Simvastatin; Thromboplastin; Thrombosis; Up-Regulation | 2005 |
Simvastatin reduces CD40 expression in an experimental model of early arterialization of saphenous vein graft.
Topics: Aged; Anticholesteremic Agents; Blood Pressure; CD40 Antigens; CD40 Ligand; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Nitric Oxide; Saphenous Vein; Simvastatin; Thrombosis; Up-Regulation | 2006 |
Lectin-like oxidized-LDL receptor-1 (LOX-1) polymorphisms influence cardiovascular events rate during statin treatment.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Drug Resistance; Female; Heptanoic Acids; Heterozygote; Humans; Hypercholesterolemia; Male; Middle Aged; Polymorphism, Genetic; Pyrroles; Retrospective Studies; Risk Factors; Scavenger Receptors, Class E; Simvastatin; Thrombosis | 2007 |
Simvastatin-oral anticoagulant interaction.
Topics: Acenocoumarol; Aged; Anticholesteremic Agents; Anticoagulants; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Simvastatin; Thrombosis | 1996 |
Increased thrombotic vascular events after change of statin.
Topics: Anticholesteremic Agents; Cholesterol, LDL; Drug Costs; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Simvastatin; Thrombosis; Triglycerides | 1998 |
Effects of statins in thrombosis and aortic lesion development in a dyslipemic rabbit model.
Topics: Animals; Aorta; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Male; Platelet Adhesiveness; Platelet Aggregation; Pyrroles; Rabbits; Simvastatin; Thrombosis | 1999 |
Heart lines. Do statins make blood less sticky?
Topics: Blood Coagulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin; Simvastatin; Thrombin; Thrombosis | 1999 |
Thrombotic vascular events after change of statin.
Topics: Anticholesteremic Agents; Arterial Occlusive Diseases; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Simvastatin; Thrombosis | 1999 |
Thrombotic vascular events after change of statin.
Topics: Anticholesteremic Agents; Arterial Occlusive Diseases; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Simvastatin; Thrombosis | 1999 |
Thrombotic vascular events after change of statin.
Topics: Anticholesteremic Agents; Arterial Occlusive Diseases; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Simvastatin; Thrombosis | 1999 |