Compounds > simvastatin
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simvastatin and Bile Duct Cancer

simvastatin has been researched along with Bile Duct Cancer in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, JP; Chen, W; Hao, XY; Hou, X; Liang, LJ; Yin, XY1
Choi, MH; Hong, EM; Jang, HJ; Jang, JA; Kae, SH; Koh, DH; Lee, J; Park, SW1
Buranrat, B; Kukongviriyapan, V; Prawan, A; Senggunprai, L1
Dostal, DE; Glaser, SS; Guerrier, M; Meng, F; Miller, T; Munshi, MK; Priester, S; Wise, CE; Yang, F1

Other Studies

4 other study(ies) available for simvastatin and Bile Duct Cancer

ArticleYear
Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism.
    Anti-cancer drugs, 2013, Volume: 24, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bile Duct Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; E2F1 Transcription Factor; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Oxonic Acid; Simvastatin; Tegafur; Thymidylate Synthase; Xenograft Model Antitumor Assays

2013
Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells.
    Gut and liver, 2016, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Bile Duct Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hypolipidemic Agents; Receptor, IGF Type 1; Simvastatin

2016
Simvastatin and atorvastatin as inhibitors of proliferation and inducers of apoptosis in human cholangiocarcinoma cells.
    Life sciences, 2016, May-15, Volume: 153

    Topics: Apoptosis; Atorvastatin; Bile Duct Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Reactive Oxygen Species; Simvastatin

2016
Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2011, Volume: 43, Issue:5

    Topics: Anticholesteremic Agents; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Epithelial Cells; Humans; rac1 GTP-Binding Protein; Signal Transduction; Simvastatin; Statistics, Nonparametric

2011