simvastatin has been researched along with Atheroma in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 32 (82.05) | 24.3611 |
| 2020's | 7 (17.95) | 2.80 |
| Authors | Studies |
|---|---|
| He, H; He, J; Liu, J; Liu, X; Ma, S; Xu, F; Zhang, M; Zhang, W; Zhou, X | 1 |
| Hong, S; Hou, C; Jiang, X; Lin, Q; Sheng, W; Wang, T; Ye, X; Zhang, Y; Zhao, J | 1 |
| Han, M; Han, N; Li, S; Liu, Z; Ren, Z; Wang, Y; Yin, J; Zhai, J | 1 |
| Abuduwaili, N; Guli, A; Jiang, L; Liu, X; Maney, K; Nabi, X; Sailike, J; Sun, X; Tuoliuhan, H; Wang, Y; Wu, Y | 1 |
| Kim, DH; Kim, H; Lee, CW; Lee, JS; Lee, PH; Lee, SW; Moon, DH; Oh, M; Shin, EW; Sung, C | 1 |
| Cao, Y; Darwitan, A; Das, P; Muktabar, A; Ng, KW; Nguyen, LTH; Rakshit, M; Tang, J; Venkatraman, S; Vizetto-Duarte, C; Wong, YS | 1 |
| Guo, J; Liu, Q; Lu, M; Luo, D; Rong, X; Tang, F; Wang, H; Yang, Y; Yin, M; Yu, L | 1 |
| Alexiou, C; Cicha, I; Friedrich, RP; Janko, C; Lyer, S; Pöttler, M | 1 |
| Kerner, V; Kum, S; Pande, SD; Safdar Husain, F | 1 |
| Liu, G; Liu, M; Wang, M | 1 |
| Gao, C; Li, HY; Liu, F; Wang, HR | 1 |
| Li, M; Qi, Z; Zhang, J; Zhu, K | 1 |
| Gao, Z; Jiang, H; Lu, X; Ruan, Z; Wang, Z; Wu, B; Ye, X | 1 |
| Bajaj, R; Chhabra, L; Kruger, M; Kumar, D | 1 |
| Gao, F; Kong, J; Liu, FF; Meng, X; Yang, JM; Zhang, C; Zhang, K; Zhang, Y | 1 |
| Feng, L; Guo, ZG; Li, MX; Qin, YF; Sun, YX; Tian, D; Ying, R; Yuan, Y | 1 |
| de Martin, R; Demyanets, S; Gröger, M; Heinz, M; Huber, K; Huk, I; Kaun, C; Krychtiuk, KA; Lemberger, CE; Petzelbauer, P; Rauscher, S; Stojkovic, S; Wojta, J | 1 |
| Cho, DY; Hong, JH; Hyeon, SH; Kim, CJ; Kim, EY; Kim, H; Kim, SW; Kim, TH; Kwon, JE; Lee, WS; Mintz, GS; Senguttuvan, NB; Seo, JS; Seok, JW; Weissman, NJ | 1 |
| Augusti, PR; Conte, L; da Veiga, ML; Denardin, IT; Duarte, MM; Emanuelli, T; Figueiredo, CG; Kasten, J; Quatrin, A; Roehrs, M; Ruviaro, AR; Somacal, S | 1 |
| Jiao, P; Qin, S; Song, G; Sun, X; Tian, H; Tian, S; Wu, Y; Yao, S; Yu, Y; Zhai, L; Zhang, X; Zhang, Z; Zhao, H; Zong, C | 1 |
| Chartrand, MS; Hazilawati, H; Hemn, HO; Noordin, MM; Rahman, HS; Zuki, A | 1 |
| Alexopoulos, D; Apostolakis, E; Hahalis, G; Koniari, I; Mavrilas, D; Papadaki, H; Papadimitriou, E; Papalois, A; Poimenidi, E; Xanthopoulou, I | 1 |
| Alaarg, A; da Silva, AE; Hamers, AA; Metselaar, JM; Schulte, DM; Storm, G; Stroes, ES; van der Valk, FM; van Ufford, LC; Versloot, M; Zheng, KH | 1 |
| Frostegård, J; Liu, A; Sun, J; Yan, K; Zhang, Y | 1 |
| He, J; Jiang, C; Liu, J; Wang, Z; Yang, Y; Zhang, M; Zhang, W | 1 |
| Barthwal, MK; Dikshit, M; Farooqui, M; Jain, M; Kanshana, JS; Khanna, V; Kumar, S; Misra, A; Singh, V | 1 |
| Andreadou, I; Efentakis, P; Filis, K; Iliodromitis, EK; Karageorgiadi, D; Papapetropoulos, A; Sigala, F; Zampas, P; Zografos, G | 1 |
| Chen, HW; Li, L; Li, N; Liu, RM; Wang, L; Xia, YF; Yao, YM; Yin, YX; Zhai, HX; Zhang, JJ | 1 |
| Cullen, B; Golledge, J; Moran, C; Rush, C | 1 |
| Abela, GS; Durga, S; Huang, R; Janoudi, A; Tamhane, U; Vedre, A | 1 |
| Anderson, JD; Berr, SS; Chew, JD; Christopher, JM; DiMaria, JM; Epstein, FH; Hagspiel, KD; Harthun, NL; Hunter, JR; Kramer, CM; Meyer, CH; Wang, H; West, AM; Winberry, GB | 1 |
| Alique, M; Badimon, JJ; Cimmino, G; Connolly, TM; Feuerstein, G; Fuster, V; Giannarelli, C; Ibanez, B; Ruiz, JM; Zafar, MU | 1 |
| Bian, Y; Dou, L; Li, J; Lu, Y; Man, Y; Qin, W; Shen, T; Wang, S; Xiao, C; Zhan, C | 1 |
| Kong, W; Zhu, Y | 1 |
| Chapman, MJ | 1 |
| Garcia-Garcia, HM; Okamura, T; Serruys, PW; Shin, ES | 1 |
| Bai, W; Li, H; Zheng, X; Zhou, L | 1 |
| Hirata, K; Otake, H | 1 |
| Li, LJ; Li, M; Peng, L; Xu, YZ; Yang, C; Zhang, GY; Zhang, JP; Zhou, YN | 1 |
2 review(s) available for simvastatin and Atheroma
| Article | Year |
|---|---|
Pitavastatin: novel effects on lipid parameters.
Topics: Apolipoprotein A-I; Apolipoproteins B; Atherosclerosis; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Coronary Artery Disease; Double-Blind Method; Dyslipidemias; Europe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Lipids; Multicenter Studies as Topic; Plaque, Atherosclerotic; Pyrroles; Quinolines; Randomized Controlled Trials as Topic; Russia; Simvastatin; Triglycerides | 2011 |
[Current evidence about lipid-lowering therapy and coronary plaque].
Topics: Evidence-Based Medicine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Plaque, Atherosclerotic; Simvastatin | 2011 |
2 trial(s) available for simvastatin and Atheroma
| Article | Year |
|---|---|
Comparison and analysis of the therapeutic effect of different statins in the treatment of atherosclerosis.
Topics: Adult; Aged; Atherosclerosis; Atorvastatin; Carotid Arteries; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Plaque, Atherosclerotic; Pravastatin; Simvastatin | 2018 |
The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline.
Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Azetidines; Cholesterol, LDL; Double-Blind Method; Ezetimibe; Female; Femoral Artery; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Middle Aged; Peripheral Arterial Disease; Plaque, Atherosclerotic; Prospective Studies; Simvastatin; Treatment Outcome | 2011 |
35 other study(ies) available for simvastatin and Atheroma
| Article | Year |
|---|---|
Anchoring β-CD on simvastatin-loaded rHDL for selective cholesterol crystals dissolution and enhanced anti-inflammatory effects in macrophage/foam cells.
Topics: Anti-Inflammatory Agents; Atherosclerosis; beta-Cyclodextrins; Cholesterol; Foam Cells; Humans; Inflammation; Lipoproteins, HDL; Macrophages; Plaque, Atherosclerotic; Simvastatin; Solubility | 2022 |
Xinmaikang (XMK) tablets alleviate atherosclerosis by regulating the SREBP2-mediated NLRP3/ASC/Caspase-1 signaling pathway.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Body Weight; Caspase 1; Caspases; Cholesterol, LDL; Chromatography, Liquid; Interleukin-6; Mice; Mice, Knockout, ApoE; Molecular Docking Simulation; NLR Family, Pyrin Domain-Containing 3 Protein; Plaque, Atherosclerotic; Signal Transduction; Simvastatin; Tandem Mass Spectrometry; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2024 |
Traditional Chinese patent medicine Zhixiong Capsule (ZXC) alleviated formed atherosclerotic plaque in rat thoracic artery and the mechanism investigation including blood-dissolved-component-based network pharmacology analysis and biochemical validation.
Topics: Animals; Diet, High-Fat; Drugs, Chinese Herbal; Gene Expression; Lipids; Male; Plaque, Atherosclerotic; Rats; Simvastatin; Thoracic Arteries | 2020 |
Ziziphora clinopodioides flavonoids based on network pharmacology attenuates atherosclerosis in rats induced by high-fat emulsion combined with vitamin D
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Aortic Diseases; Atherosclerosis; Cholecalciferol; Disease Models, Animal; Fat Emulsions, Intravenous; Flavonoids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lamiaceae; Lipids; Male; NF-kappa B; Oxidative Stress; Plant Extracts; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Simvastatin; Vascular Endothelial Growth Factor A | 2020 |
Statin/ezetimibe combination therapy vs statin monotherapy for carotid atherosclerotic plaque inflammation.
Topics: Acute Coronary Syndrome; Aged; C-Reactive Protein; Carotid Arteries; Carotid Artery Diseases; Cholesterol, LDL; Clinical Trials as Topic; Datasets as Topic; Ezetimibe, Simvastatin Drug Combination; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Plaque, Atherosclerotic; Rosuvastatin Calcium; Simvastatin | 2021 |
Anti-inflammatory potential of simvastatin loaded nanoliposomes in 2D and 3D foam cell models.
Topics: Atherosclerosis; Cell Line; Drug Delivery Systems; Foam Cells; Humans; Inflammation; Liposomes; Nanoparticles; Plaque, Atherosclerotic; Simvastatin; Spheroids, Cellular | 2021 |
Downregulations of CD36 and Calpain-1, Inflammation, and Atherosclerosis by Simvastatin in Apolipoprotein E Knockout Mice.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Calpain; CD36 Antigens; Disease Models, Animal; Down-Regulation; Genetic Predisposition to Disease; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Interleukin-6; Lipoproteins, LDL; Male; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Plaque, Atherosclerotic; Simvastatin; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2017 |
Treat or track: nanoagents in the service of health.
Topics: Alzheimer Disease; Animals; Anticholesteremic Agents; Cell Tracking; Drug Delivery Systems; Embryonic Stem Cells; Humans; Multiple Sclerosis; Nanomedicine; Nanoparticles; Optical Imaging; Plaque, Atherosclerotic; Protein Corona; Simvastatin | 2017 |
Complete resolution of extensive thrombosis of atheromatous non-aneurysmal descending aorta and pulmonary embolism with warfarin therapy.
Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Brain; Carotid Stenosis; Drug Therapy, Combination; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Middle Aged; Plaque, Atherosclerotic; Pulmonary Embolism; Simvastatin; Stroke; Warfarin | 2018 |
Protective effect of simvastatin on arterial plaque instability induced by p-cresyl sulfate.
Topics: Animals; Cresols; Lipids; Male; Matrix Metalloproteinases; Mice; Plaque, Atherosclerotic; Protective Agents; Simvastatin; Sulfuric Acid Esters | 2018 |
Si-Miao-Yong-An on promoting the maturation of Vasa Vasorum and stabilizing atherosclerotic plaque in ApoE
Topics: Animals; Apolipoproteins E; Atherosclerosis; Drugs, Chinese Herbal; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Plaque, Atherosclerotic; Simvastatin; Vasa Vasorum | 2019 |
Simvastatin reduces atherosclerotic plaques and endothelial inflammatory response in atherosclerosis rats through TGF-β/Smad pathway.
Topics: Animals; Anticholesteremic Agents; Aorta; Carotid Artery Diseases; Coronary Artery Disease; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipids; Plaque, Atherosclerotic; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Simvastatin; Smad Proteins; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2020 |
Mobile complex atherosclerotic aortic plaque.
Topics: Aortic Diseases; Diagnosis, Differential; Echocardiography, Transesophageal; Humans; Hypolipidemic Agents; Male; Middle Aged; Plaque, Atherosclerotic; Simvastatin | 2013 |
Simvastatin increases Prolyl-4-Hydroxylase α1 expression in atherosclerotic plaque and ox-LDL-stimulated human aortic smooth muscle cells via p38 MAPK and ERK1/2 signaling.
Topics: Animals; Aorta; Body Weight; Collagen; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Lipids; Lipoproteins, LDL; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plaque, Atherosclerotic; Prolyl Hydroxylases; Simvastatin; Time Factors | 2013 |
The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cholesterol; Cholesterol, LDL; Drug Therapy, Combination; Gene Expression; Hypolipidemic Agents; Lipoproteins; Liver X Receptors; Male; Mice; Mice, Knockout; Molecular Mimicry; Orphan Nuclear Receptors; Peptides; Plaque, Atherosclerotic; PPAR gamma; Scavenger Receptors, Class B; Simvastatin | 2013 |
Interleukin-33 induces urokinase in human endothelial cells--possible impact on angiogenesis.
Topics: Angiogenesis Inducing Agents; Carotid Arteries; Carotid Artery Diseases; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Interleukins; Neovascularization, Physiologic; NF-kappa B; Plaque, Atherosclerotic; Receptors, Cell Surface; Recombinant Proteins; RNA Interference; RNA, Messenger; Signal Transduction; Simvastatin; Time Factors; Transfection; Up-Regulation; Urokinase-Type Plasminogen Activator | 2014 |
Frequency and evolution of thin-capped fibroatheromas in left main coronary artery as assessed by serial virtual histology intravascular ultrasound analysis.
Topics: Aged; Atorvastatin; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Phenotype; Plaque, Atherosclerotic; Pyrroles; Quinolines; Registries; Retrospective Studies; Simvastatin; Ultrasonography, Interventional | 2014 |
The antiatherogenic effect of bixin in hypercholesterolemic rabbits is associated to the improvement of lipid profile and to its antioxidant and anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Atherosclerosis; Body Weight; Carotenoids; Hypercholesterolemia; Lipids; Male; Oxidation-Reduction; Plaque, Atherosclerotic; Rabbits; Simvastatin; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Tunica Intima | 2015 |
Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
Topics: Animals; Apoptosis; Atherosclerosis; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Hydrogen; Macrophages; Mice; Mice, Knockout; NF-E2-Related Factor 2; Plaque, Atherosclerotic; Reactive Oxygen Species; Receptors, LDL; Receptors, Oxidized LDL; Simvastatin | 2015 |
Antihypercholesterolemic and antioxidant efficacies of zerumbone on the formation, development, and establishment of atherosclerosis in cholesterol-fed rabbits.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Aorta; Aortic Diseases; Atherosclerosis; Biomarkers; Cholesterol, Dietary; Dietary Supplements; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Malondialdehyde; Oxidative Stress; Plaque, Atherosclerotic; Rabbits; Sesquiterpenes; Simvastatin; Superoxide Dismutase; Time Factors | 2015 |
Inhibition of Atherosclerosis Progression, Intimal Hyperplasia, and Oxidative Stress by Simvastatin and Ivabradine May Reduce Thoracic Aorta's Stiffness in Hypercholesterolemic Rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Benzazepines; Diet, Atherogenic; Disease Models, Animal; Disease Progression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperplasia; Ivabradine; Male; Neointima; Oxidative Stress; Plaque, Atherosclerotic; Rabbits; Simvastatin; Vascular Stiffness | 2016 |
Multiple pathway assessment to predict anti-atherogenic efficacy of drugs targeting macrophages in atherosclerotic plaques.
Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Cell Proliferation; Cytokines; Endoplasmic Reticulum Stress; High-Throughput Screening Assays; Humans; Hydrocarbons, Fluorinated; Inflammation; Inflammation Mediators; Lipid Metabolism; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Plaque, Atherosclerotic; Prednisolone; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Simvastatin; Stilbenes; Sulfonamides; Transfection | 2016 |
Oxidized Low-Density Lipoprotein (OxLDL)-Treated Dendritic Cells Promote Activation of T Cells in Human Atherosclerotic Plaque and Blood, Which Is Repressed by Statins: microRNA let-7c Is Integral to the Effect.
Topics: Atorvastatin; Cell Differentiation; Chaperonin 60; Dendritic Cells; Endarterectomy, Carotid; Extracellular Signal-Regulated MAP Kinases; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Interleukin-17; Interleukin-1beta; Interleukin-6; Lipoproteins, LDL; Lymphocyte Activation; MicroRNAs; Mitochondrial Proteins; Molecular Chaperones; Nuclear Receptor Subfamily 1, Group F, Member 3; Phosphorylation; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; T-Box Domain Proteins; T-Lymphocytes; Th1 Cells; Th17 Cells; Tumor Necrosis Factor-alpha | 2016 |
Plaque-hyaluronidase-responsive high-density-lipoprotein-mimetic nanoparticles for multistage intimal-macrophage-targeted drug delivery and enhanced anti-atherosclerotic therapy.
Topics: Animals; Cholesterol; Coculture Techniques; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Lactic Acid; Lipoproteins, HDL; Macrophages; Male; Mice; Nanoparticles; Particle Size; Plaque, Atherosclerotic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; RAW 264.7 Cells; Simvastatin; Static Electricity; Tunica Intima | 2017 |
Progression and Characterization of the Accelerated Atherosclerosis in Iliac Artery of New Zealand White Rabbits: Effect of Simvastatin.
Topics: Angioplasty, Balloon; Animals; Atherosclerosis; Biomarkers; Diet, High-Fat; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Extracellular Matrix; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iliac Artery; Inflammation Mediators; Lipids; Macrophages; Male; Plaque, Atherosclerotic; Rabbits; Simvastatin; Time Factors; Vascular Remodeling; Vasoconstriction; Vasodilation | 2017 |
Reciprocal regulation of eNOS, H
Topics: Aged; Aged, 80 and over; Carotid Stenosis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Female; Heme Oxygenase-1; Humans; Hydrogen Sulfide; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; NADPH Oxidase 4; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Plaque, Atherosclerotic; Prospective Studies; Proto-Oncogene Proteins c-akt; Simvastatin | 2017 |
[The effect of simvastatin on the expression of high mobility group box-1 protein in atherosclerotic rats].
Topics: Animals; Atherosclerosis; Disease Models, Animal; HMGB1 Protein; Male; Plaque, Atherosclerotic; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Simvastatin | 2010 |
Efficacy of simvastatin in reducing aortic dilatation in mouse models of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Lipids; Male; Mice; Mice, Transgenic; Plaque, Atherosclerotic; Receptors, Lipoprotein; Simvastatin | 2010 |
Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization.
Topics: Animals; Atorvastatin; Cholesterol; Crystallization; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Microscopy, Electron, Scanning; Plaque, Atherosclerotic; Pravastatin; Pyrroles; Rabbits; Simvastatin | 2011 |
Synergistic effect of liver X receptor activation and simvastatin on plaque regression and stabilization: an magnetic resonance imaging study in a model of advanced atherosclerosis.
Topics: Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Chemokine CCL2; Cyclooxygenase 2; Disease Progression; Drug Combinations; Drug Synergism; Indazoles; Liver X Receptors; Magnetic Resonance Angiography; Orphan Nuclear Receptors; Plaque, Atherosclerotic; Rabbits; Random Allocation; Simvastatin; Thromboplastin; Up-Regulation | 2012 |
Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p(53), Bcl-2 and Bcl-xL.
Topics: Animals; Aorta; Apolipoproteins E; Apoptosis; Atherosclerosis; bcl-X Protein; Blood Glucose; Brachiocephalic Trunk; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-bcl-2; Simvastatin; Tumor Suppressor Protein p53 | 2012 |
The pleiotropic effects of statins in the prevention of atherosclerosis : Editorial to: "Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p53, Bcl-2 en Bcl-xL" by Weiwei Qin et al.
Topics: Animals; Apoptosis; Atherosclerosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Plaque, Atherosclerotic; Simvastatin | 2012 |
Effect of statins on coronary bifurcation atherosclerosis: an intravascular ultrasound virtual histology study.
Topics: Aged; Chi-Square Distribution; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Disease Progression; Female; Fibrosis; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Male; Middle Aged; Necrosis; Odds Ratio; Plaque, Atherosclerotic; Predictive Value of Tests; Pyrimidines; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Time Factors; Treatment Outcome; Ultrasonography, Interventional; Vascular Calcification | 2012 |
Prostaglandin E1 dose-dependently promotes stability of atherosclerotic plaque in a rabbit model.
Topics: Alprostadil; Angioplasty, Balloon; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Cardiovascular Agents; Chemokine CCL2; Cholesterol, Dietary; Cytokines; Daboia; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Fibrosis; Histamine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipid Metabolism; Macrophages; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Plaque, Atherosclerotic; Rabbits; RNA, Messenger; Simvastatin; Viper Venoms | 2012 |
Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model.
Topics: Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Atherosclerosis; Blood Coagulation; Cholesterol, Dietary; Cholesterol, LDL; Cytokines; Drugs, Chinese Herbal; Inflammation; Inflammation Mediators; Lipids; Macrophages; Magnoliopsida; Male; Myocytes, Smooth Muscle; Phytotherapy; Plaque, Atherosclerotic; Rabbits; Simvastatin; Triglycerides | 2012 |