Page last updated: 2024-08-23

simvastatin and Aortic Diseases

simvastatin has been researched along with Aortic Diseases in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (42.11)29.6817
2010's10 (52.63)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Abuduwaili, N; Guli, A; Jiang, L; Liu, X; Maney, K; Nabi, X; Sailike, J; Sun, X; Tuoliuhan, H; Wang, Y; Wu, Y1
Guo, J; Liu, Q; Lu, M; Luo, D; Rong, X; Tang, F; Wang, H; Yang, Y; Yin, M; Yu, L1
Kerner, V; Kum, S; Pande, SD; Safdar Husain, F1
Bajaj, R; Chhabra, L; Kruger, M; Kumar, D1
Chartrand, MS; Hazilawati, H; Hemn, HO; Noordin, MM; Rahman, HS; Zuki, A1
Alexopoulos, D; Apostolakis, E; Hahalis, G; Koniari, I; Mavrilas, D; Papadaki, H; Papadimitriou, E; Papalois, A; Poimenidi, E; Xanthopoulou, I1
Chai, YS; Fu, WJ; Ke, J; Lei, T; Nie, H; Pan, JH; Paranjpe, M; Qu, L; Wang, ZH; Wu, G; Xu, RH; Xu, XY; Yan, YX; Yin, Z1
Agarwal, S; Desai, M; Gautam, S; Gottlieb, I; Lima, JA; Steen, H; Warren, WP; Xavier, SS1
Bobková, D; Havlíčková, J; Kovář, J; Pitha, J; Poledne, R1
Feng, JB; Ji, XP; Jiang, H; Liu, CX; Liu, Y; Lu, XT; Wang, R; Wu, YL; Xu, XS; Zhang, C; Zhang, L; Zhang, Y; Zhao, YX1
Kappagoda, CT; Karalliedde, LD1
Cheriyan, J; Cherry, L; Davidson, EH; Kharbanda, RK; Mäki-Petäjä, KM; McEniery, CM; Sattar, N; Wallace, SM; Wilkinson, IB1
Alique, M; Badimon, JJ; Cimmino, G; Connolly, TM; Feuerstein, G; Fuster, V; Giannarelli, C; Ibanez, B; Ruiz, JM; Zafar, MU1
Bai, W; Li, H; Zheng, X; Zhou, L1
Desai, MY; Gautam, S; Lai, S; Lima, JA; Steen, H; Warren, WP1
Wang, YX1
Almeida, EA; Carneiro, A; Jorge, M; Jorge, PA; Ozaki, MR1
Bellasi, A; Raggi, P1
Badimon, JJ; Chesebro, J; Corti, R; Fayad, ZA; Fuster, V; Helft, G; Mercuri, M; Worthley, SG1

Reviews

2 review(s) available for simvastatin and Aortic Diseases

ArticleYear
Cardiovascular functional phenotypes and pharmacological responses in apolipoprotein E deficient mice.
    Neurobiology of aging, 2005, Volume: 26, Issue:3

    Topics: Angiotensin II; Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Cardiac Output, High; Cardiomegaly; Cardiovascular System; Enzyme Inhibitors; Estradiol; Hypercholesterolemia; Hyperglycemia; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Phenotype; Simvastatin

2005
[Atherosclerosis imaging to assess plaque progression].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2005, Volume: 6, Issue:8

    Topics: Adult; Aged; Animals; Aortic Diseases; Arteriosclerosis; Calcinosis; Cardiovascular Diseases; Carotid Artery Diseases; Clinical Trials as Topic; Coronary Angiography; Coronary Artery Disease; Cost-Benefit Analysis; Disease Progression; Female; Follow-Up Studies; Humans; Hypolipidemic Agents; Magnetic Resonance Imaging; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin; Time Factors; Tomography, X-Ray Computed

2005

Trials

4 trial(s) available for simvastatin and Aortic Diseases

ArticleYear
Aortic plaque regression as determined by magnetic resonance imaging with high-dose and low-dose statin therapy.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2008, Volume: 9, Issue:7

    Topics: Aged; Aortic Diseases; Arteriosclerosis; Cholesterol; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Magnetic Resonance Imaging, Cine; Male; Simvastatin

2008
Simvastatin prevents inflammation-induced aortic stiffening and endothelial dysfunction.
    British journal of clinical pharmacology, 2010, Volume: 70, Issue:6

    Topics: Adult; Aorta; Aortic Diseases; Blood Flow Velocity; Double-Blind Method; Endothelium, Vascular; Female; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Lipids; Male; Salmonella typhi; Salmonella Vaccines; Simvastatin; Vasodilation; Young Adult

2010
Statin-induced cholesterol lowering and plaque regression after 6 months of magnetic resonance imaging-monitored therapy.
    Circulation, 2004, Oct-19, Volume: 110, Issue:16

    Topics: Aged; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Cholesterol, LDL; Comorbidity; Coronary Disease; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Observer Variation; Prospective Studies; Reproducibility of Results; Simvastatin; Smoking; Stroke

2004
Effects of lipid-lowering by simvastatin on human atherosclerotic lesions: a longitudinal study by high-resolution, noninvasive magnetic resonance imaging.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Aorta; Aortic Diseases; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Cholesterol; Cholesterol, LDL; Humans; Hypolipidemic Agents; Longitudinal Studies; Magnetic Resonance Imaging; Remission Induction; Simvastatin; Treatment Outcome; Vascular Patency

2001

Other Studies

13 other study(ies) available for simvastatin and Aortic Diseases

ArticleYear
Ziziphora clinopodioides flavonoids based on network pharmacology attenuates atherosclerosis in rats induced by high-fat emulsion combined with vitamin D
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Aortic Diseases; Atherosclerosis; Cholecalciferol; Disease Models, Animal; Fat Emulsions, Intravenous; Flavonoids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lamiaceae; Lipids; Male; NF-kappa B; Oxidative Stress; Plant Extracts; Plaque, Atherosclerotic; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Simvastatin; Vascular Endothelial Growth Factor A

2020
Downregulations of CD36 and Calpain-1, Inflammation, and Atherosclerosis by Simvastatin in Apolipoprotein E Knockout Mice.
    Journal of vascular research, 2017, Volume: 54, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Calpain; CD36 Antigens; Disease Models, Animal; Down-Regulation; Genetic Predisposition to Disease; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Interleukin-6; Lipoproteins, LDL; Male; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Plaque, Atherosclerotic; Simvastatin; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2017
Complete resolution of extensive thrombosis of atheromatous non-aneurysmal descending aorta and pulmonary embolism with warfarin therapy.
    BMJ case reports, 2018, Apr-27, Volume: 2018

    Topics: Anticoagulants; Aorta, Thoracic; Aortic Diseases; Brain; Carotid Stenosis; Drug Therapy, Combination; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Male; Middle Aged; Plaque, Atherosclerotic; Pulmonary Embolism; Simvastatin; Stroke; Warfarin

2018
Mobile complex atherosclerotic aortic plaque.
    BMJ case reports, 2013, Apr-20, Volume: 2013

    Topics: Aortic Diseases; Diagnosis, Differential; Echocardiography, Transesophageal; Humans; Hypolipidemic Agents; Male; Middle Aged; Plaque, Atherosclerotic; Simvastatin

2013
Antihypercholesterolemic and antioxidant efficacies of zerumbone on the formation, development, and establishment of atherosclerosis in cholesterol-fed rabbits.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Anticholesteremic Agents; Antioxidants; Aorta; Aortic Diseases; Atherosclerosis; Biomarkers; Cholesterol, Dietary; Dietary Supplements; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Malondialdehyde; Oxidative Stress; Plaque, Atherosclerotic; Rabbits; Sesquiterpenes; Simvastatin; Superoxide Dismutase; Time Factors

2015
Inhibition of Atherosclerosis Progression, Intimal Hyperplasia, and Oxidative Stress by Simvastatin and Ivabradine May Reduce Thoracic Aorta's Stiffness in Hypercholesterolemic Rabbits.
    Journal of cardiovascular pharmacology and therapeutics, 2016, Volume: 21, Issue:4

    Topics: Animals; Antioxidants; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Benzazepines; Diet, Atherogenic; Disease Models, Animal; Disease Progression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperplasia; Ivabradine; Male; Neointima; Oxidative Stress; Plaque, Atherosclerotic; Rabbits; Simvastatin; Vascular Stiffness

2016
Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis.
    Journal of ethnopharmacology, 2017, Jan-04, Volume: 195

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Thoracic; Aortic Diseases; Apoptosis; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Cholecalciferol; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Enzymes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Inflammation Mediators; Lipids; Male; Myocardium; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats, Sprague-Dawley; Simvastatin; Tablets; Time Factors

2017
Antiatherogenic effect of simvastatin is not due to decrease of LDL cholesterol in ovariectomized golden Syrian hamster.
    Physiological research, 2010, Volume: 59, Issue:3

    Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Cricetinae; Disease Models, Animal; Drug Administration Schedule; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Mesocricetus; Ovariectomy; Simvastatin; Time Factors; Triglycerides

2010
Traditional Chinese medication Tongxinluo dose-dependently enhances stability of vulnerable plaques: a comparison with a high-dose simvastatin therapy.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aortic Diseases; Aortic Rupture; Atherosclerosis; Biomarkers; Catheterization; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gene Expression Regulation; Gene Transfer Techniques; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Inflammation Mediators; Lipids; Male; Rabbits; RNA, Messenger; Simvastatin; Time Factors; Tumor Suppressor Protein p53; Ultrasonography, Doppler, Duplex; Ultrasonography, Interventional; Viper Venoms

2009
The challenge of traditional Chinese medicines for allopathic practitioners.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aortic Diseases; Aortic Rupture; Atherosclerosis; Biomarkers; Cardiovascular Agents; Complementary Therapies; Disease Progression; Drugs, Chinese Herbal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipids; Simvastatin

2009
Synergistic effect of liver X receptor activation and simvastatin on plaque regression and stabilization: an magnetic resonance imaging study in a model of advanced atherosclerosis.
    European heart journal, 2012, Volume: 33, Issue:2

    Topics: Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Chemokine CCL2; Cyclooxygenase 2; Disease Progression; Drug Combinations; Drug Synergism; Indazoles; Liver X Receptors; Magnetic Resonance Angiography; Orphan Nuclear Receptors; Plaque, Atherosclerotic; Rabbits; Random Allocation; Simvastatin; Thromboplastin; Up-Regulation

2012
Prostaglandin E1 dose-dependently promotes stability of atherosclerotic plaque in a rabbit model.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:2

    Topics: Alprostadil; Angioplasty, Balloon; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Cardiovascular Agents; Chemokine CCL2; Cholesterol, Dietary; Cytokines; Daboia; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Fibrosis; Histamine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipid Metabolism; Macrophages; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Plaque, Atherosclerotic; Rabbits; RNA, Messenger; Simvastatin; Viper Venoms

2012
[Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits].
    Arquivos brasileiros de cardiologia, 2005, Volume: 84, Issue:4

    Topics: Animals; Anticholesteremic Agents; Aortic Diseases; Arteriosclerosis; Atorvastatin; Cholesterol; Cholesterol, LDL; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hypercholesterolemia; Indoles; Lipid Peroxidation; Male; Malondialdehyde; Pravastatin; Pyrroles; Rabbits; Simvastatin

2005