simvastatin has been researched along with Angiogenesis, Pathologic in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banciu, M; Licarete, E; Luput, L; Mot, AC; Patras, L; Porfire, A; Rakosy-Tican, E; Rauca, VF; Sesarman, A; Toma, VA | 1 |
| Chen, H; Gao, X; Li, J; Li, Y; Liu, J; Liu, P; Ren, Y; Song, S; Wang, B; Wang, H; Wang, R; Wang, Y; Zhang, M | 1 |
| Achim, M; Banciu, M; Casian, T; Dragos, N; Drotar, DM; Licarete, E; Luput, L; Muntean, D; Patras, L; Porfire, A; Rauca, VF; Sesarman, A; Stejerean, I; Toma, VA; Tomuta, I; Vlase, L | 1 |
| Cong, LL; Feng, J; Li, GY; Li, WM; Li, XX; Liu, PJ; Lu, SY; Sun, JL; Sun, X; Wang, JC; Ye, YP | 1 |
| Banciu, M; Bulzu, P; Licarete, E; Luput, L; Patras, L; Rakosy-Tican, E; Rauca, VF; Sesarman, A | 1 |
| Li, M; Qi, Z; Zhang, J; Zhu, K | 1 |
| Al-Husein, B; Goc, A; Somanath, PR | 1 |
| Ahn, KS; Chen, L; Kumar, AP; Li, F; Manu, KA; Sethi, G; Shanmugam, MK; Siveen, KS | 1 |
| Kang, WK; Lee, I; Lee, J; Lee, SJ; Park, C | 1 |
| Lee, KI; Lee, TS; Lin, SJ; Shyue, SK; Su, KH; Wei, J; Zhao, JF | 1 |
| Alupei, MC; Banciu, M; Licarete, E; Patras, L | 1 |
| Li, G; Ling, J; Qiu, W; Wang, Y; Xu, B; Zheng, J | 1 |
| Chade, AR; Daghini, E; Lavi, R; Lerman, A; Lerman, LO; Napoli, C; Zhu, XY | 1 |
| Hermonat, PL; Kang, BY; Khaidakov, M; Khan, JA; Mehta, JL; Wang, W | 1 |
| Fan, WH; Jin, B; Li, Y; Luo, XP; Shen, W; Shi, HM | 1 |
| Chen, J; Chopp, M; Cui, X; Dai, J; Kuzmin-Nichols, N; Ning, R; Roberts, C; Sanberg, CD; Shehadah, A; Yan, T; Zacharek, A; Zhang, C | 1 |
| Tony, JC | 1 |
| Feleszko, W; Mlynarczuk, I; Nowis, D | 1 |
| Herrmann, J; Holmes, DR; Lerman, A; Lerman, LO; Napoli, C; Ritman, EL; Wilson, SH | 1 |
| Csiszar, A; Pacher, P; Ungvari, Z | 1 |
20 other study(ies) available for simvastatin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Remodeling tumor microenvironment by liposomal codelivery of DMXAA and simvastatin inhibits malignant melanoma progression.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; Liposomes; Macrophages; Male; Melanoma; Melanoma, Cutaneous Malignant; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oxidative Stress; Simvastatin; Skin Neoplasms; Tumor Microenvironment; Xanthones | 2021 |
Metformin and simvastatin synergistically suppress endothelin 1-induced hypoxia and angiogenesis in multiple cancer types.
Topics: Animals; Cell Line, Tumor; Endothelin-1; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Metformin; Mice; Neoplasms; Neovascularization, Pathologic; Simvastatin | 2023 |
Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5-fluorouracil in vivo.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Liposomes; Mice; Neovascularization, Pathologic; NF-kappa B; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-bcl-2; Simvastatin; Xenograft Model Antitumor Assays | 2020 |
Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fibroblast Growth Factor 2; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Simvastatin; Vascular Endothelial Growth Factor A | 2018 |
Combination therapy of simvastatin and 5, 6-dimethylxanthenone-4-acetic acid synergistically suppresses the aggressiveness of B16.F10 melanoma cells.
Topics: Angiogenesis Inhibitors; Animals; Cell Communication; Cell Movement; Cell Proliferation; Coculture Techniques; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Macrophages; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Simvastatin; Tumor Microenvironment; Xanthones | 2018 |
Si-Miao-Yong-An on promoting the maturation of Vasa Vasorum and stabilizing atherosclerotic plaque in ApoE
Topics: Animals; Apolipoproteins E; Atherosclerosis; Drugs, Chinese Herbal; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Plaque, Atherosclerotic; Simvastatin; Vasa Vasorum | 2019 |
Suppression of interactions between prostate tumor cell-surface integrin and endothelial ICAM-1 by simvastatin inhibits micrometastasis.
Topics: beta Catenin; Cell Communication; Cell Line, Tumor; Cell Membrane; Endothelial Cells; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Intercellular Adhesion Molecule-1; Male; Models, Biological; Neoplasm Micrometastasis; Neovascularization, Pathologic; Prostatic Neoplasms; Protein Binding; Protein Stability; Simvastatin | 2013 |
Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Capecitabine; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Disease Models, Animal; DNA; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mice; Mice, Nude; Neovascularization, Pathologic; NF-kappa B; Protein Binding; Simvastatin; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90α in human colorectal cancer.
Topics: Angiogenesis Inhibitors; Angiopoietin-2; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Cell Line, Tumor; Cell Movement; Cell Survival; Colorectal Neoplasms; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Peritoneal Neoplasms; Simvastatin; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
The essential role of transient receptor potential vanilloid 1 in simvastatin-induced activation of endothelial nitric oxide synthase and angiogenesis.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Endothelial Cells; Mice, Inbred C57BL; Neovascularization, Pathologic; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Signal Transduction; Simvastatin; TRPV Cation Channels | 2014 |
Liposomal simvastatin inhibits tumor growth via targeting tumor-associated macrophages-mediated oxidative stress.
Topics: Animals; Blotting, Western; Catalase; Cell Proliferation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit; Liposomes; Macrophages; Male; Malondialdehyde; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Nitric Oxide; Oxidative Stress; Simvastatin; Tumor Cells, Cultured | 2015 |
Simvastatin inhibits tumor angiogenesis in HER2-overexpressing human colorectal cancer.
Topics: Angiogenesis Inhibitors; Bevacizumab; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Neovascularization, Pathologic; Neuregulin-1; Receptor, ErbB-2; Simvastatin; Vascular Endothelial Growth Factor A | 2017 |
Disparate effects of simvastatin on angiogenesis during hypoxia and inflammation.
Topics: Cell Hypoxia; Cell Line; Endothelial Cells; Endothelium, Vascular; Humans; Hypolipidemic Agents; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Models, Biological; Neovascularization, Pathologic; Oxidative Stress; Simvastatin; Tumor Necrosis Factor-alpha | 2008 |
Statins and angiogenesis: is it about connections?
Topics: Angiogenesis Inhibitors; Animals; Antigens, CD; Aorta; Cadherins; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Neovascularization, Physiologic; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Umbilical Veins | 2009 |
The effects of simvastatin on angiogenesis: studied by an original model of atherosclerosis and acute myocardial infarction in rabbit.
Topics: Animals; Aorta, Thoracic; Atherosclerosis; Coronary Angiography; Disease Models, Animal; Heart Function Tests; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lipids; Male; Myocardial Infarction; Neovascularization, Pathologic; Rabbits; Simvastatin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Combination treatment of stroke with sub-therapeutic doses of Simvastatin and human umbilical cord blood cells enhances vascular remodeling and improves functional outcome.
Topics: Analysis of Variance; Angiopoietins; Animals; Antibodies; Anticholesteremic Agents; Arteries; Bromodeoxyuridine; Cell Movement; Cells, Cultured; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Lectins; Linear Models; Male; Neovascularization, Pathologic; Neovascularization, Physiologic; Rats; Rats, Wistar; Simvastatin; Stroke; Time Factors | 2012 |
Alzheimer's disease and angiogenesis.
Topics: Alzheimer Disease; Angiogenesis Inhibitors; Cerebral Cortex; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neovascularization, Pathologic; Simvastatin | 2003 |
In vitro antitumor activity of cerivastatin, a novel and potent HMG-CoA reductase inhibitor.
Topics: Antineoplastic Agents; Cell Division; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Neovascularization, Pathologic; Pyridines; Simvastatin; Tumor Cells, Cultured | 2001 |
Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering.
Topics: Animals; Blotting, Western; Cholesterol; Coronary Angiography; Coronary Vessels; Diet, Atherogenic; Endothelial Growth Factors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lymphokines; Matrix Metalloproteinases; Neovascularization, Pathologic; Simvastatin; Swine; Tomography, X-Ray Computed; Transcription Factors; Vasa Vasorum; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Can simvastatin promote tumor growth by inducing angiogenesis similar to VEGF?
Topics: Endothelial Growth Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphokines; Neovascularization, Pathologic; Simvastatin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |