Page last updated: 2024-08-23

simvastatin and Angiitis

simvastatin has been researched along with Angiitis in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's11 (68.75)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bemtgen, X; Bode, C; Grundmann, S; Helbing, T; Hoefer, I; Hohnloser, C; Jaenich, C; Juschkat, M; Kreuzaler, S; Martin, J; Mastroianni, J; Moser, M; Pankratz, F; Pasterkamp, G; Schneider, L; Smolka, C; Zeiser, R1
Al-Ani, B1
Chen, XY; Lan, D; Li, T; Liu, LM; Tian, KL; Wu, Y; Yang, GM; Zhu, Y1
Paraskevas, KI1
Chen, JH; Liao, JK; Lin, LJ; Liu, PY; Liu, YW1
Pasternak, RC; Tershakovec, AM; Veltri, EP1
Visseren, FL; Westerink, J1
Pernow, J; Rydén, L; Settergren, M1
Cremonesi, B; Gelosa, P; Gianazza, E; Gianella, A; Guerrini, U; Nobili, E; Paoletti, R; Sironi, L; Tremoli, E1
Han, SH; Koh, KK; Lee, Y; Quon, MJ; Shin, EK1
Dahm, JB; Felix, SB; Jantzen, F; Landsberger, M; Rosenstengel, C; Staudt, A; Vogelgesang, D; Wolff, B1
Fukuo, K; Katuya, T; Kawamoto, H; Kotani, N; Ogihara, T; Sugimoto, K; Suzuki, A; Takemura, Y; Yasuda, O; Yokoi, T1
Hirata, K; Ishida, T; Kojima, Y; Okada, T; Quertermous, T; Tanaka, H; Yasuda, T; Yokoyama, M1
Aoki, T; Hashimoto, N; Ishibashi, R; Kataoka, H; Nozaki, K1
Bui, MN; Cannon, RO; Cardillo, C; Csako, G; Hathaway, L; Koh, KK; Panza, JA; Waclawiw, MA1
Lefer, AM; Pruefer, D; Scalia, R1

Trials

4 trial(s) available for simvastatin and Angiitis

ArticleYear
Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation.
    Circulation, 2009, Jan-06, Volume: 119, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Activation; Ezetimibe; Female; Humans; Hyperlipidemias; Leukocytes; Male; Middle Aged; Prospective Studies; rho-Associated Kinases; Simvastatin; Triglycerides; Vasculitis; Vasodilation

2009
The effects of simvastatin, losartan, and combined therapy on soluble CD40 ligand in hypercholesterolemic, hypertensive patients.
    Atherosclerosis, 2007, Volume: 190, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; C-Reactive Protein; CD40 Ligand; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lipids; Losartan; Male; Middle Aged; Simvastatin; Solubility; Vasculitis; Vasodilation

2007
Fas ligand mRNA levels of circulating leukocytes reflect endothelial dysfunction in hyperlipidemic but not in non-hyperlipidemic patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:4

    Topics: Aged; Apoptosis; Atherosclerosis; Biomarkers; Brachial Artery; Endothelium, Vascular; Fas Ligand Protein; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Jurkat Cells; Leukocytes; Lipoproteins, LDL; Male; Membrane Glycoproteins; Middle Aged; Predictive Value of Tests; Regional Blood Flow; RNA, Messenger; Simvastatin; Tumor Necrosis Factors; Up-Regulation; Vasculitis

2006
Vascular effects of estrogen and cholesterol-lowering therapies in hypercholesterolemic postmenopausal women.
    Circulation, 1999, Jan-26, Volume: 99, Issue:3

    Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Drug Therapy, Combination; E-Selectin; Endothelium, Vascular; Estrogens; Female; Fibrinolysis; Hormone Replacement Therapy; Humans; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Middle Aged; Plasminogen Activator Inhibitor 1; Postmenopause; Simvastatin; Vascular Cell Adhesion Molecule-1; Vasculitis; Vasodilation; Vasomotor System

1999

Other Studies

12 other study(ies) available for simvastatin and Angiitis

ArticleYear
MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy.
    Circulation research, 2018, 02-02, Volume: 122, Issue:3

    Topics: Animals; Atherosclerosis; Autophagy; Carotid Artery Diseases; Cell Adhesion Molecules; Cholesterol, LDL; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Receptors, LDL; Simvastatin; Specific Pathogen-Free Organisms; TOR Serine-Threonine Kinases; Transcriptome; Vasculitis

2018
Simvastatin inhibits neutrophil degranulation induced by anti-neutrophil cytoplasm auto-antibodies and N-formyl-methionine-leucine-phenylalanine (fMLP) peptide.
    Saudi medical journal, 2013, Volume: 34, Issue:5

    Topics: Animals; Antibodies, Antineutrophil Cytoplasmic; Cell Degranulation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Inbred WKY; Simvastatin; Vasculitis

2013
Diabetes and hyperlipidemia induce dysfunction of VSMCs: contribution of the metabolic inflammation/miRNA pathway.
    American journal of physiology. Endocrinology and metabolism, 2015, Feb-15, Volume: 308, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Connexins; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Drug Therapy, Combination; Female; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Male; Metformin; MicroRNAs; Muscle, Smooth, Vascular; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Renal Artery; rho-Associated Kinases; Simvastatin; Vasculitis

2015
Statins suppress the development of aneurysms: fact or fiction?
    Stroke, 2008, Volume: 39, Issue:8

    Topics: Animals; Aortic Aneurysm, Abdominal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Aneurysm; Simvastatin; Vasculitis

2008
Letter by Tershakovec et al regarding article, "Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation".
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Humans; Hyperlipidemias; rho-Associated Kinases; Risk Factors; Simvastatin; Vasculitis

2009
Letter by Westerink and Visseren regarding article, "Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation".
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Humans; Hyperlipidemias; rho-Associated Kinases; Simvastatin; Vasculitis

2009
Letter by Settergren et al regarding article, "Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation".
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Endothelium, Vascular; Ezetimibe; Humans; Hyperlipidemias; rho-Associated Kinases; Simvastatin; Vasculitis

2009
Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:3

    Topics: Acute-Phase Proteins; Animals; Cerebral Arteries; Chemokine CCL2; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; P-Selectin; Proteinuria; Pyrimidines; Rats; Rats, Inbred SHR; RNA, Messenger; Rosuvastatin Calcium; Simvastatin; Sodium Chloride, Dietary; Stroke; Sulfonamides; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vasculitis

2005
Cerivastatin reduces cytokine-induced surface expression of ICAM-1 via increased shedding in human endothelial cells.
    Atherosclerosis, 2007, Volume: 190, Issue:1

    Topics: Cells, Cultured; Cytoplasm; Dactinomycin; Endothelial Cells; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Membrane Proteins; NF-KappaB Inhibitor alpha; Nucleic Acid Synthesis Inhibitors; Pyridines; RNA, Messenger; Simvastatin; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1; Vasculitis

2007
Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages.
    Journal of atherosclerosis and thrombosis, 2007, Volume: 14, Issue:4

    Topics: Animals; Cholesterol, LDL; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipase; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Simvastatin; Toll-Like Receptor 4; Vasculitis

2007
Simvastatin suppresses the progression of experimentally induced cerebral aneurysms in rats.
    Stroke, 2008, Volume: 39, Issue:4

    Topics: Animals; Chemokine CCL2; Disease Models, Animal; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Interleukin-1beta; Intracranial Aneurysm; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Simvastatin; Vascular Cell Adhesion Molecule-1; Vasculitis

2008
Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:12

    Topics: Animals; Anticholesteremic Agents; Blood Pressure; Cell Communication; Cell Movement; Cholesterol; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Hemostatics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocytes; Male; Mesenteric Veins; Microscopy; NG-Nitroarginine Methyl Ester; Nitric Oxide; P-Selectin; Rats; Rats, Sprague-Dawley; Simvastatin; Thrombin; Tromethamine; Vasculitis; Venules

1999