simvastatin has been researched along with Alveolar Bone Atrophy in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 18 (62.07) | 24.3611 |
| 2020's | 4 (13.79) | 2.80 |
| Authors | Studies |
|---|---|
| Barbirato, DDS; Diniz, JA; do Nascimento, EHL; Dourado, ACAG; Laureano Filho, JR; Pontual, ADA | 1 |
| Abdel-Ghaffar, KA; Al-Shahat, MA; Gamal, AY; Hassan, AAA; Iacono, VJ; Issa, DR | 1 |
| Calasans-Maia, MD; Cruz, R; de Almeida, DCF; Granjeiro, JM; Moraschini, V; Sartoretto, SC | 1 |
| Chen, N; Lele, SM; Li, G; Mukundan, R; Reinhardt, RA; Ren, R; Wang, D; Wei, X; Xu, X; Zhao, G; Zhao, Z | 1 |
| Berke, M; Giannini, PJ; Jia, Z; Liu, J; Nawshad, A; Reinhardt, RA; Samson, K; Schmid, M; Wang, D; Wang, X; Willett, ES; Yu, F | 1 |
| Bak, EJ; Cha, JH; Kim, A; Kim, AR; Kim, JH; Sohn, Y; Yoo, YJ | 1 |
| AlSwafeeri, H; ElKenany, W; Karam, S; Mowafy, M | 1 |
| Chao, YL; Hong, CY; Hou, KL; Kok, SH; Lai, EH; Lee, MS; Lin, LD; Lin, SK; Wang, JS; Yang, H | 1 |
| Bajaj, P; Kumari, M; Naik, SB; Pradeep, AR; Rao, NS | 1 |
| Haycraft, CJ; Huang, Y; Jin, J; Kirkwood, KL; Li, Q; Li, Y; Lopes-Virella, MF; Lu, Z; Yu, H; Zhang, X | 1 |
| Costa, TP; Fávero, GM; Fernandes, D; Machado, WM; Mendes, RT; Olchanheski, LR; Otuki, MF; Prestes, AP; Santos, FA; Sordi, R; Vellosa, JC | 1 |
| Huang, Y; Jin, J; Kirkwood, KL; Li, Y; Lopes-Virella, MF; Lu, Z; Machado, ER; Yu, H; Zhang, X | 1 |
| Battistetti, GD; da Costa, KF; Faccioni, DM; Kottwitz, LB; Marconato, J; Marin, CF; Nahsan, FP; Nassar, CA; Nassar, PO; Olegário, J | 1 |
| Chen, H; Liu, XQ; Lu, EY; Qin, A; Xu, XC; Zhai, ZJ; Zhang, X | 1 |
| Bradley, AD; Jia, Z; Pranke, L; Reinhardt, RA; Schmid, MJ; Wang, D; Wang, X; Zhang, Y; Zhao, G | 1 |
| Giannini, PJ; Lavin, MT; Lee, Y; Marx, DB; Morris, MS; Reinhardt, RA; Schmid, MJ | 1 |
| Andia, DC; Aquino, SG; Guimarães, MR; Muscara, MN; Nassar, CA; Nassar, PO; Rossa, C; Spolidorio, DM; Spolidorio, LC | 1 |
| Chen, MH; Hong, CY; Hou, KL; Kok, SH; Lee, YL; Lin, SK; Lin, YT; Wang, CC | 1 |
| Arana-Chavez, VE; Bradaschia-Correa, V; Maciel-Oliveira, N | 1 |
| Chen, S; Feng, L; Ren, J; Yang, JY; Zhang, SY | 1 |
| Kalra, N; Martande, S; Naik, SB; Pradeep, AR; Priyanka, N; Singh, SP | 1 |
| Killeen, AC; Marx, DB; Narayana, N; Payne, JB; Rakes, PA; Reinhardt, RA; Schmid, MJ; Wang, D; Zhang, Y | 1 |
| Bajaj, P; Kumari, M; Pradeep, AR; Rao, NS | 1 |
| Brito, GA; Dalcico, R; de Menezes, AM; Deocleciano, OB; Oriá, RB; Ribeiro, RA; Vale, ML | 1 |
| Le, HO; Marx, DB; Narayana, N; Powell, SE; Price, U; Reinhardt, RA; Schmid, MJ; Wang, D; Zhang, Y | 1 |
| Liu, ST; Sun, HC; Wang, Y; Wu, Z | 1 |
| Dehpour, AR; Eslami, B; Khojasteh, A; Mashhadi-Abbas, F; Naserhojjati-Roodsari, R; Tahsili-Fahadan, N; Vaziri, H | 1 |
| Liu, C; Sun, H; Wu, Z; Zang, G | 1 |
| Hama, H; Horibe, M; Nagata, T; Ohba, H; Seto, H; Tokunaga, K | 1 |
6 trial(s) available for simvastatin and Alveolar Bone Atrophy
| Article | Year |
|---|---|
Tomographic evaluation of the effect of simvastatin topical use on alveolar bone microarchitecture, pain and swelling after mandibular third molar extraction: a randomized controlled trial.
Topics: Alveolar Bone Loss; Alveolar Ridge Augmentation; Edema; Humans; Molar, Third; Pain; Simvastatin; Single-Blind Method; Tooth Extraction; Tooth Socket | 2022 |
Guided tissue regeneration of intrabony defects with perforated barrier membranes, simvastatin, and EDTA root surface modification: A clinical and biochemical study.
Topics: Adult; Alveolar Bone Loss; Edetic Acid; Female; Follow-Up Studies; Gingival Crevicular Fluid; Guided Tissue Regeneration, Periodontal; Humans; Male; Membranes, Artificial; Middle Aged; Periodontal Attachment Loss; Periodontal Pocket; Prospective Studies; Simvastatin; Treatment Outcome | 2020 |
Clinical efficacy of simvastatin gel combined with polypropylene membrane on the healing of extraction sockets: A triple-blind, randomized clinical trial.
Topics: Alveolar Bone Loss; Alveolar Ridge Augmentation; Humans; Polypropylenes; Simvastatin; Tooth Extraction; Tooth Socket; Treatment Outcome | 2021 |
Simvastatin local drug delivery in smokers with chronic periodontitis: a randomized controlled clinical trial.
Topics: Adult; Alveolar Bone Loss; Bone Density Conservation Agents; Chemotherapy, Adjuvant; Chronic Periodontitis; Delayed-Action Preparations; Dental Scaling; Gels; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Periodontal Index; Root Planing; Simvastatin; Smoking | 2013 |
Clinical efficacy of subgingivally delivered 1.2-mg simvastatin in the treatment of individuals with Class II furcation defects: a randomized controlled clinical trial.
Topics: Adult; Alveolar Bone Loss; Bone Regeneration; Chi-Square Distribution; Dental Scaling; Drug Carriers; Female; Gels; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylcellulose; Middle Aged; Periodontal Index; Radiography; Simvastatin; Single-Blind Method; Statistics, Nonparametric; Stents | 2012 |
Efficacy of subgingivally delivered simvastatin in the treatment of patients with type 2 diabetes and chronic periodontitis: a randomized double-masked controlled clinical trial.
Topics: Adult; Alveolar Bone Loss; Chronic Periodontitis; Delayed-Action Preparations; Dental Scaling; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Image Processing, Computer-Assisted; Longitudinal Studies; Male; Middle Aged; Osteogenesis; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Placebos; Root Planing; Simvastatin; Treatment Outcome | 2013 |
23 other study(ies) available for simvastatin and Alveolar Bone Atrophy
| Article | Year |
|---|---|
Thermoresponsive Hydrogel-Based Local Delivery of Simvastatin for the Treatment of Periodontitis.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Drug Carriers; Drug Liberation; Female; Humans; Hydrogels; Injections, Intralesional; Mice; Models, Animal; Periodontitis; Poloxamer; Rats; RAW 264.7 Cells; Simvastatin; Solubility; X-Ray Microtomography | 2021 |
Standardized Rat Model Testing Effects of Inflammation and Grafting on Extraction Healing.
Topics: Alveolar Bone Loss; Animals; Bone Remodeling; Bone Transplantation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Maxilla; Molar; Rats; Simvastatin; Tooth Extraction; Tooth Socket; Wound Healing; X-Ray Microtomography | 2017 |
Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis.
Topics: Alveolar Bone Loss; Animals; Blood Glucose; Body Weight; Bone Morphogenetic Proteins; Bone Resorption; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fasting; Genetic Markers; Lipoproteins, LDL; Male; Osteoclasts; Periodontitis; Rats, Inbred F344; Simvastatin; Tibia; Triglycerides | 2018 |
Effect of local administration of simvastatin on orthodontic tooth movement in rabbits.
Topics: Alveolar Bone Loss; Animals; Bone Remodeling; Bone Resorption; Male; Mandible; Models, Animal; Nickel; Orthodontic Appliances; Orthodontic Wires; Osteoclasts; Rabbits; Simvastatin; Titanium; Tooth Movement Techniques | 2019 |
Simvastatin suppresses osteoblastic expression of Cyr61 and progression of apical periodontitis through enhancement of the transcription factor Forkhead/winged helix box protein O3a.
Topics: 3T3 Cells; Alveolar Bone Loss; Animals; Cell Line; Chemokine CCL2; Chemotaxis; Cysteine-Rich Protein 61; Disease Models, Animal; Disease Progression; Forkhead Box Protein O3; Forkhead Transcription Factors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice; Osteoblasts; Periapical Periodontitis; Radiography, Dental, Digital; Rats; Rats, Sprague-Dawley; Simvastatin; Tumor Necrosis Factor-alpha | 2013 |
Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal disease.
Topics: Acid Phosphatase; Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Gingiva; Gingivitis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Isoenzymes; Lipopolysaccharides; Matrix Metalloproteinase 9; Maxillary Diseases; Osteoclasts; Periodontal Diseases; Rats; Rats, Sprague-Dawley; Simvastatin; Tartrate-Resistant Acid Phosphatase; Toll-Like Receptors; X-Ray Microtomography | 2014 |
The effect of simvastatin on systemic inflammation and endothelial dysfunction induced by periodontitis.
Topics: Acetylcholine; Alveolar Bone Loss; Animals; Arterial Pressure; C-Reactive Protein; Disease Models, Animal; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Interleukin-6; Leukocyte Count; Lipids; Male; Nitroprusside; Periodontitis; Random Allocation; Rats; Rats, Wistar; Simvastatin; Vasodilator Agents | 2014 |
Simvastatin inhibits LPS-induced alveolar bone loss during metabolic syndrome.
Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Blood Glucose; Chemotaxis, Leukocyte; Cholesterol; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Interleukin-6; Leukocytes; Lipopolysaccharides; Metabolic Syndrome; Osteoclasts; Palmitic Acid; Periodontitis; RANK Ligand; Rats; Rats, Zucker; Simvastatin; Triglycerides; X-Ray Microtomography | 2014 |
Evaluation of the effect of simvastatin on the progression of alveolar bone loss in experimental periodontitis--an animal study.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Chronic Periodontitis; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Radiography; Random Allocation; Rats; Rats, Wistar; Simvastatin | 2014 |
Simvastatin prevents alveolar bone loss in an experimental rat model of periodontitis after ovariectomy.
Topics: Alveolar Bone Loss; Animals; Biomarkers; Biomechanical Phenomena; Cell Count; Dental Cementum; Dental Enamel; Disease Models, Animal; Female; Femur; Osteocalcin; Osteoclasts; Osteogenesis; Ovariectomy; Periodontitis; Rats, Sprague-Dawley; Simvastatin; X-Ray Microtomography | 2014 |
Effect of Simvastatin Prodrug on Experimental Periodontitis.
Topics: Alveolar Bone Loss; Animals; Anticholesteremic Agents; Female; Periodontitis; Prodrugs; Rats; Rats, Sprague-Dawley; Simvastatin; X-Ray Microtomography | 2016 |
Injectable simvastatin in periodontal defects and alveolar ridges: pilot studies.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Bicuspid; Bone Regeneration; Dental Cementum; Dogs; Drug Carriers; Female; Furcation Defects; Gels; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections; Jaw, Edentulous, Partially; Male; Mandibular Diseases; Methylcellulose; Molar; Osteogenesis; Pilot Projects; Random Allocation; Simvastatin; Time Factors | 2008 |
Simvastatin therapy in cyclosporine A-induced alveolar bone loss in rats.
Topics: Alkaline Phosphatase; Alveolar Bone Loss; Alveolar Process; Animals; Anti-Inflammatory Agents; Bone Density; Calcium; Cell Count; Cyclosporine; Dinoprostone; Down-Regulation; Gingiva; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Interleukin-1beta; Male; Mouth Mucosa; Nitric Oxide Synthase Type II; Osteoblasts; Osteoclasts; Phosphorus; Random Allocation; Rats; Rats, Sprague-Dawley; Simvastatin | 2009 |
Simvastatin as a novel strategy to alleviate periapical lesions.
Topics: Alveolar Bone Loss; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blotting, Western; Cell Count; Cell Line; Chemokine CCL2; Chemotaxis; Cysteine-Rich Protein 61; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Macrophages; Osteoblasts; Periapical Periodontitis; Radiography, Dental, Digital; Rats; Rats, Sprague-Dawley; Simvastatin; Tumor Necrosis Factor-alpha | 2009 |
Early alveolar bone regeneration in rats after topical administration of simvastatin.
Topics: Administration, Topical; Alveolar Bone Loss; Alveolar Process; Animals; Bone Marrow; Bone Matrix; Bone Regeneration; Bone Resorption; Collagen; Gels; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Male; Mandible; Mandibular Diseases; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Osteoblasts; Osteogenesis; Osteopontin; Rats; Rats, Wistar; Simvastatin; Time Factors | 2011 |
Effects of simvastatin gel on bone regeneration in alveolar defects in miniature pigs.
Topics: Alveolar Bone Loss; Animals; Bone Regeneration; Guided Tissue Regeneration, Periodontal; Simvastatin; Swine; Swine, Miniature | 2011 |
Impact of local and systemic alendronate on simvastatin-induced new bone around periodontal defects.
Topics: Administration, Topical; Alendronate; Alveolar Bone Loss; Animals; Bone Density Conservation Agents; Bone Regeneration; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Mandible; Rats; Rats, Sprague-Dawley; Simvastatin | 2012 |
Protective mechanisms of simvastatin in experimental periodontal disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Bone Morphogenetic Protein 2; Female; Gingiva; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Interleukin-1beta; Malondialdehyde; Matrix Metalloproteinase 1; Matrix Metalloproteinase 8; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Osteoprotegerin; Oxidative Stress; Periodontitis; Peroxidase; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Simvastatin; Tumor Necrosis Factor-alpha | 2013 |
Effects of local simvastatin-alendronate conjugate in preventing periodontitis bone loss.
Topics: Alendronate; Alveolar Bone Loss; Animals; beta-Cyclodextrins; Bone Density Conservation Agents; Drug Combinations; Endotoxins; Escherichia coli; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imaging, Three-Dimensional; Injections; Lipopolysaccharides; Maxillary Diseases; Molar; Osteoclasts; Palate; Periodontitis; Premedication; Rats; Rats, Sprague-Dawley; Sequestering Agents; Simvastatin; X-Ray Microtomography | 2013 |
[Effect of simvastatin on residual ridge resorption after tooth extraction].
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Lactic Acid; Male; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Simvastatin; Tooth Extraction | 2006 |
Effect of simvastatin administration on periodontitis-associated bone loss in ovariectomized rats.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Bone Density; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Injections; Mandible; Osteogenesis; Ovariectomy; Periodontal Attachment Loss; Periodontitis; Rats; Simvastatin | 2007 |
The effect of simvastatin on remodelling of the alveolar bone following tooth extraction.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Biocompatible Materials; Bone Density; Bone Remodeling; Disease Models, Animal; Drug Carriers; Drug Implants; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incisor; Lactic Acid; Male; Mandible; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Random Allocation; Rats; Rats, Wistar; Simvastatin; Time Factors; Tooth Extraction; Tooth Socket | 2008 |
Topical administration of simvastatin recovers alveolar bone loss in rats.
Topics: Administration, Topical; Alkaline Phosphatase; Alveolar Bone Loss; Animals; Bone Regeneration; Cells, Cultured; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Osteoblasts; Periodontitis; Rats; Rats, Inbred F344; Simvastatin; Skull; Tomography | 2008 |