Page last updated: 2024-08-23

simvastatin and Age-Related Macular Degeneration

simvastatin has been researched along with Age-Related Macular Degeneration in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (36.36)	29.6817
2010's	7 (63.64)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bederman, IR; Mast, N; Pikuleva, IA	1
Gan, WL; Guymer, R; Hodgson, L; Kawasaki, R; Lamoureux, E; Lee, KY; Robman, L; Sasaki, M; Wong, TY	1
Aung, KZ; Baird, PN; Busija, L; Dimitrov, PN; Guymer, RH; Lim, L; Makeyeva, GA; Richardson, AJ; Robman, LD; Varsamidis, M	1
Barathi, VA; Guymer, RH; Luu, CD; Wong, TY; Yeo, SW	1
Gehlbach, P; Hatef, E; Li, T	4
Baird, PN; Dimitrov, PN; Guymer, RH; Lim, LL; Robman, L; Varsamidis, M; Vingrys, AJ	1
Chakravarthy, U; Cook, C; Fletcher, AE; Hubbard, R; Smeeth, L	1
Kumar, A; Misra, A; Pandey, RM; Sen, K	1

Reviews

4 review(s) available for simvastatin and Age-Related Macular Degeneration

Article	Year
Statins for age-related macular degeneration. The Cochrane database of systematic reviews, 2015, Feb-11, Issue:2 Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin	2015
Statins for age-related macular degeneration. The Cochrane database of systematic reviews, 2016, Aug-04, Issue:8 Topics: Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Male; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin; Visual Acuity	2016
Statins for age-related macular degeneration. The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3 Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Randomized Controlled Trials as Topic; Simvastatin	2009
Statins for age-related macular degeneration. The Cochrane database of systematic reviews, 2012, Mar-14, Issue:3 Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Randomized Controlled Trials as Topic; Simvastatin	2012

Trials

3 trial(s) available for simvastatin and Age-Related Macular Degeneration

Article	Year
Proof of concept, randomized, placebo-controlled study of the effect of simvastatin on the course of age-related macular degeneration. PloS one, 2013, Volume: 8, Issue:12 Topics: Aged; Aged, 80 and over; Apolipoprotein E2; Complement Factor H; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Male; Middle Aged; Polymorphism, Genetic; Prognosis; Risk Factors; Simvastatin	2013
Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS). Clinical interventions in aging, 2008, Volume: 3, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Male; Middle Aged; Prospective Studies; Simvastatin; Surveys and Questionnaires; Treatment Outcome; Visual Acuity	2008
Simvastatin retards progression of retinopathy in diabetic patients with hypercholesterolemia. Diabetes research and clinical practice, 2002, Volume: 56, Issue:1 Topics: Blood Glucose; Blood Pressure; Cholesterol, LDL; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Fundus Oculi; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Macular Degeneration; Photography; Placebos; Simvastatin; Visual Acuity	2002

Other Studies

4 other study(ies) available for simvastatin and Age-Related Macular Degeneration

Article	Year
Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol. Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:11 Topics: Animals; Cholesterol; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Macular Degeneration; Male; Mice; Mice, Inbred C57BL; Retina; Simvastatin; Up-Regulation	2018
Effect of simvastatin on retinal vascular caliber: the Age-Related Maculopathy Statin Study. Acta ophthalmologica, 2013, Volume: 91, Issue:5 Topics: Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular Degeneration; Middle Aged; Randomized Controlled Trials as Topic; Retinal Vessels; Simvastatin	2013
Effects of simvastatin on retinal structure and function of a high-fat atherogenic mouse model of thickened Bruch's membrane. Investigative ophthalmology & visual science, 2014, Jan-23, Volume: 55, Issue:1 Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Bruch Membrane; Disease Models, Animal; Electroretinography; Follow-Up Studies; Macular Degeneration; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Pigment Epithelium of Eye; Simvastatin; Treatment Outcome	2014
A case control study of age related macular degeneration and use of statins. The British journal of ophthalmology, 2005, Volume: 89, Issue:9 Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anticholesteremic Agents; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Drug Administration Schedule; Family Practice; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Macular Degeneration; Male; Middle Aged; Reproducibility of Results; Risk Assessment; Simvastatin; Smoking	2005