simvastatin has been researched along with Adenocarcinoma in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 4 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, L; Fullerton, DA; Gergen, AK; Li, A; Madsen, HJ; Meng, X; Pratap, A; Weyant, MJ | 1 |
| Beer, DG; Chang, AC; Ferrer-Torres, D; Hinton, T; Jiang, H; Lagisetty, K; Lawrence, TS; Lin, J; Nancarrow, D; Owens, S; Ray, D; Ray, P; San Martinho, M; Thomas, D; Wang, Z; Yoon, HW | 1 |
| Alexandre, L; Cheong, EC; Clark, AB; Dresner, SM; Flather, M; Hammond, M; Hart, AR; Jones, M; Kadirkamanathan, SS; Kumar, B; Lewis, MP; Loke, YK; Parsons, SL; Sims, E; Swart, AM; Walton, S; Warren, H | 1 |
| Fullerton, DA; Gergen, AK; Halpern, AL; Kohtz, PD; Meng, X; Weyant, MJ; White, AM | 1 |
| Cridge, J; Doherty, GJ; Gao, M; Griffiths, M; Hall, BA; Kerr, EM; Martins, CP; Samarajiwa, S; Shorthouse, D; Speed, A; Thorpe, H; Turrell, FK | 1 |
| Chen, Y; Li, LB; Tang, DP; Wei, JJ; Zhang, J; Zhuang, ZH | 1 |
| Albertsson, M; Holmqvist, A; Kotti, A; Sun, XF | 1 |
| Di Virgilio, A; Falcone, D; Gallelli, L; Pelaia, G; Savino, R; Scaramuzzino, M; Terracciano, R; Tucci, L | 1 |
| D'Agostino, B; Falcone, D; Gallelli, L; Maselli, R; Mesuraca, M; Navarra, M; Pelaia, G; Savino, R; Scaramuzzino, M; Spaziano, G; Terracciano, R | 1 |
| Duan, Z; El-Serag, HB; Kramer, JR; Naik, AD; Nguyen, T | 1 |
| Bang, S; Chung, MJ; Lee, HJ; Lee, HS; Lee, SH; Park, JY; Park, SW; Song, SY | 1 |
| Fullerton, DA; Meng, X; Reece, TB; Reppert, AE; Sadaria, MR; Weyant, MJ; Yu, JA | 1 |
| Alayoubi, AY; Anderson, JF; Nazzal, S; Satyanarayanajois, SD; Sylvester, PW | 1 |
| Chen, Y; Li, W; Li, Y; Liu, H; Wang, Z | 1 |
| Bellini, MJ; de Alaniz, MJ; de Bravo, MG; Polo, MP | 1 |
| Burnat, G; Hahn, EG; Konturek, PC | 1 |
| Beales, IL; Ogunwobi, OO | 1 |
| Hawk, ET; Viner, JL | 1 |
| Fukaura, Y; Ishikawa, C; Narisawa, T; Tanida, N; Terada, K; Umezawa, A; Yazawa, K | 1 |
| Namiki, M; Nishino, N; Obara, T; Okamura, K; Tanno, S; Ura, H | 1 |
1 trial(s) available for simvastatin and Adenocarcinoma
| Article | Year |
|---|---|
Adjuvant statin therapy for oesophageal adenocarcinoma: the STAT-ROC feasibility study.
Topics: Adenocarcinoma; Aged; Chemotherapy, Adjuvant; Cholesterol, LDL; Combined Modality Therapy; Double-Blind Method; Esophageal Neoplasms; Esophagectomy; Feasibility Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Medication Adherence; Middle Aged; Quality of Life; Simvastatin; Treatment Outcome; United Kingdom | 2020 |
19 other study(ies) available for simvastatin and Adenocarcinoma
| Article | Year |
|---|---|
Simvastatin Inhibits Histologic Changes Associated with Gastroduodenal Reflux in a Murine Model.
Topics: Adenocarcinoma; Animals; Annexin A5; Barrett Esophagus; Caspase 3; Disease Models, Animal; Esophageal Neoplasms; Esophagitis, Peptic; Gastroesophageal Reflux; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Simvastatin | 2022 |
Isoforms of RNF128 Regulate the Stability of Mutant P53 in Barrett's Esophageal Cells.
Topics: Adenocarcinoma; Animals; Barrett Esophagus; Cells, Cultured; Down-Regulation; Esophageal Neoplasms; Esophagus; Female; Gene Expression; Gene Silencing; Glycosylation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Isoenzymes; Mice; Mice, Nude; Neoplasm Transplantation; RNA, Messenger; Signal Transduction; Simvastatin; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases | 2020 |
Statins Inhibit Toll-Like Receptor 4-Mediated Growth of Human Esophageal Adenocarcinoma Cells.
Topics: Adenocarcinoma; Animals; Atorvastatin; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Disease Progression; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipopolysaccharides; Mice; Mice, Nude; Myeloid Differentiation Factor 88; Random Allocation; Signal Transduction; Simvastatin; Toll-Like Receptor 4; Tumor Burden; Xenograft Model Antitumor Assays | 2021 |
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genotype; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lung Neoplasms; Mice; Molecular Targeted Therapy; Mutation; Piperazines; Simvastatin; Tumor Suppressor Protein p53 | 2017 |
Simvastatin, but not pravastatin, inhibits the proliferation of esophageal adenocarcinoma and squamous cell carcinoma cells: a cell-molecular study.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation; Humans; Pravastatin; Simvastatin | 2018 |
Survival benefit of statins in older patients with rectal cancer: A Swedish population-based cohort study.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Atorvastatin; Cohort Studies; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Staging; Pravastatin; Proportional Hazards Models; Protective Factors; Rectal Neoplasms; Retrospective Studies; Simvastatin; Survival Rate; Sweden | 2019 |
Effects of simvastatin and rosuvastatin on RAS protein, matrix metalloproteinases and NF-κB in lung cancer and in normal pulmonary tissues.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antineoplastic Agents; Biomarkers, Tumor; Blotting, Western; Case-Control Studies; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorobenzenes; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Pyrimidines; ras Proteins; Rosuvastatin Calcium; Simvastatin; Smoking; Sulfonamides; Transcription Factor RelA; Tumor Cells, Cultured | 2013 |
Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; GPI-Linked Proteins; Humans; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-8; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myeloid Differentiation Factor 88; NF-kappa B; Signal Transduction; Simvastatin; TNF Receptor-Associated Death Domain Protein; TNF Receptor-Associated Factor 2; TNF Receptor-Associated Factor 6 | 2014 |
Statin use reduces risk of esophageal adenocarcinoma in US veterans with Barrett's esophagus: a nested case-control study.
Topics: Adenocarcinoma; Adult; Aged; Barrett Esophagus; Case-Control Studies; Chemoprevention; Dose-Response Relationship, Drug; Esophageal Neoplasms; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Logistic Models; Male; Middle Aged; Neoplasm Staging; Pharmacoepidemiology; Risk Assessment; Simvastatin; United States; Veterans | 2015 |
Statin Use and Its Impact on Survival in Pancreatic Cancer Patients.
Topics: Adenocarcinoma; Aged; Anticholesteremic Agents; Atorvastatin; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pancreatic Neoplasms; Proportional Hazards Models; Retrospective Studies; Risk Factors; Simvastatin; Survival Rate; Time Factors | 2016 |
Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Atorvastatin; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Esophageal Neoplasms; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; NF-kappa B; Pravastatin; Pyrroles; Simvastatin | 2011 |
Concurrent delivery of tocotrienols and simvastatin by lipid nanoemulsions potentiates their antitumor activity against human mammary adenocarcenoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Combinations; Drug Compounding; Drug Delivery Systems; Drug Stability; Drug Synergism; Emulsions; Fat Emulsions, Intravenous; Female; Humans; Nanostructures; Simvastatin; Solubility; Surface Properties; Tocotrienols; Triglycerides; Viscosity | 2013 |
Simvastatin prevents proliferation and bone metastases of lung adenocarcinoma in vitro and in vivo.
Topics: Acyl Coenzyme A; Adenocarcinoma; Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Bone Neoplasms; Cell Proliferation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Tumor Cells, Cultured | 2013 |
Effect of simvastatin on the uptake and metabolic conversion of palmitic, dihomo-gamma-linoleic and alpha-linolenic acids in A549 cells.
Topics: Adenocarcinoma; alpha-Linolenic Acid; Anticholesteremic Agents; Cell Line; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Linoleic Acid; Lung Neoplasms; Palmitic Acid; Phospholipids; Simvastatin | 2003 |
Inhibition of Barret's adenocarcinoma cell growth by simvastatin: involvement of COX-2 and apoptosis-related proteins.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Barrett Esophagus; bcl-2-Associated X Protein; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dose-Response Relationship, Drug; Esophageal Neoplasms; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin | 2007 |
Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Apoptosis; Barrett Esophagus; Caspase 3; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Esophageal Neoplasms; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Lovastatin; Mevalonic Acid; Nitrobenzenes; Polyisoprenyl Phosphates; Pravastatin; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Sulfonamides | 2008 |
Statins in esophageal cancer cell lines: promising lead?
Topics: Adenocarcinoma; Animals; Apoptosis; Barrett Esophagus; Cell Line, Tumor; Dose-Response Relationship, Drug; Esophageal Neoplasms; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pravastatin; Simvastatin | 2008 |
Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Cholesterol; Colonic Neoplasms; Dimethylhydrazines; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred ICR; Pravastatin; Simvastatin | 1994 |
Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene.
Topics: Adenocarcinoma; Animals; Base Sequence; Cell Cycle; Codon; Cricetinae; DNA, Neoplasm; Genes, ras; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Molecular Sequence Data; Pancreatic Neoplasms; Point Mutation; Protein Prenylation; Proto-Oncogene Proteins p21(ras); Sensitivity and Specificity; Simvastatin; Tumor Cells, Cultured | 1994 |