simvastatin has been researched along with Acute Relapsing Multiple Sclerosis in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enzevaei, A; Firouznia, K; Ghanaati, H; Harirchian, MH; Jannati, A; Karvigh, SA; Moghadam, NB; Nabavi, M; Nourian, A; Sahraian, MA; Shekiba, M; Togha, M | 1 |
| Edland, A; Erälinna, JP; Frederiksen, JL; Lycke, J; Malmeström, C; Oturai, A; Sellebjerg, F; Sondergaard, HB; Sorensen, PS; Stenager, E; Wu, X | 1 |
| Steinman, L; Zamvil, SS | 1 |
| Markovic-Plese, S; Tao, Y; Troiani, L; Zhang, X | 1 |
| Garcia-Mata, R; Markovic-Plese, S; Tao, Y; Wang, J; Zhang, X | 1 |
| Corboy, J; Durkalski, V; Key, L; Markovic-Plese, S; Preiningerova, J; Rizzo, M; Singh, I; Tyor, W; Vollmer, T | 1 |
3 trial(s) available for simvastatin and Acute Relapsing Multiple Sclerosis
| Article | Year |
|---|---|
Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: a double-blind randomized controlled trial.
Topics: Adjuvants, Immunologic; Adult; Contrast Media; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; Female; Gadolinium; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Interferon beta-1a; Interferon-beta; Iran; Magnetic Resonance Imaging; Male; Multiple Sclerosis, Relapsing-Remitting; Simvastatin; Treatment Outcome; Young Adult | 2010 |
Simvastatin as add-on therapy to interferon β-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial.
Topics: Adolescent; Adult; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Interferon beta-1a; Interferon-beta; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Simvastatin; Young Adult | 2011 |
Oral simvastatin treatment in relapsing-remitting multiple sclerosis.
Topics: Adjuvants, Immunologic; Administration, Oral; Adolescent; Adult; Brain; Contrast Media; Female; Gadolinium; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Simvastatin | 2004 |
3 other study(ies) available for simvastatin and Acute Relapsing Multiple Sclerosis
| Article | Year |
|---|---|
Combining statins with interferon β in multiple sclerosis: think twice, it might not be all right.
Topics: Administration, Oral; Drug Therapy, Combination; Humans; Injections, Intramuscular; Interferon beta-1a; Interferon-beta; Multiple Sclerosis, Relapsing-Remitting; Protein Binding; Randomized Controlled Trials as Topic; Receptors, Interferon; Simvastatin | 2011 |
Simvastatin inhibits IFN regulatory factor 4 expression and Th17 cell differentiation in CD4+ T cells derived from patients with multiple sclerosis.
Topics: Adolescent; Adult; Blotting, Western; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Separation; Coculture Techniques; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Knockdown Techniques; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon Regulatory Factors; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Th17 Cells; Young Adult | 2011 |
Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting multiple sclerosis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigen Presentation; Cell Differentiation; Cells, Cultured; Cytokines; Dendritic Cells; Female; Gene Expression Regulation; Humans; Immunomodulation; Lymphocyte Activation; Male; Middle Aged; Monocytes; Multiple Sclerosis, Relapsing-Remitting; Simvastatin; Th1 Cells; Th1-Th2 Balance; Th17 Cells; Young Adult | 2013 |