Page last updated: 2024-08-23

simvastatin and Acute Disease

simvastatin has been researched along with Acute Disease in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (20.00)18.2507
2000's26 (52.00)29.6817
2010's13 (26.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Andres, AM; de Freitas Germano, J; Gaisano, HY; Gottlieb, RA; Gulla, A; Hou, J; Lugea, A; Marek-Iannucci, S; Pandol, SJ; Piplani, H; Saadaeijahromi, H; Sharma, A; Sin, J; Song, Y; Takahashi, T; Waldron, RT; Wu, B1
Arumugam, S; Ramalingam, S; Solairaja, S; Subbiah, V; Thiyagaraj, A; Venkatabalasubramanian, S; Venkatasubramanian, A1
Ateş, G; Aydın, I; Ergüven, M; Özkök, E; Tamer, Ş; Yorulmaz, H1
Akyüz, F; Çomunoğlu, N; Iş, M; Üzüm, G; Yavuz, Ö; Yıldırım, HA; Yüksel, H1
Alvez, G; Barreto-Filho, JA; Bezerra, OC; Bortoloto, LA; Brasileiro-Santos, MS; Chacra, AP; Consolim-Colombo, FM; Irigoyen, MC; Sangaleti, CT; Santos, RD1
Liu, IL; Pandol, SJ; Wu, BU1
Long, HB; Luo, KQ; Xu, BC1
Talukdar, R; Vege, SS1
Chang, CH; Chio, CC; Hu, CY; Kuo, JR; Liao, JC; Lim, SW; Shiue, YL; Wang, CC; Wee, HY1
Al Shohaib, S; Bahlas, S; Waness, A1
Almeida, JL; Jukemura, J; Machado, MC; Mendonça Coelho, AM; Monteiro da Cunha, JE; Sampietre, SN; Trindade Molan, NA1
Dafa-Berger, A; Dyer, MD; Fishman, D; Katze, MG; Paeper, B; Proll, SC; Rager-Zisman, B; Robinzon, S; Rom, S; Teal, TH1
Faergeman, O; Fayyad, R; Holdaas, H; Holme, I; Kastelein, JJ; Larsen, ML; Lindahl, C; Olsson, AG; Pedersen, TR; Tikkanen, MJ1
Baker, M; Gupta, A; Maguire, M; Muwanga, C; Seidi, O1
Isenmann, S; Krempler, K; Löwel, S; Schmeer, CW; Witte, OW1
Adami, M; Cabrini, DA; Horinouchi, CD; Mendes, DA; Otuki, MF; Prudente, Ada S1
Almeida-Leite, CM; Bahia, MT; Leite, R; Shrestha-Bajracharya, D; Silva, RR; Talvani, A1
Blé-Castillo, JL; Díaz-Zagoya, JC; Juárez-Oropeza, MA; Miranda-Zamora, R; Rodríguez-Hernández, A1
Cui, L; Gao, M; Hu, D; Liu, X; Wei, Y; Xu, Z; Yang, X; Zou, Y1
Kutluay, L; Oskay, T1
Isomustajärvi, M; Laakso, J; Laaksonen, R; Lakka, TA; Lehtimäki, T; Päivä, H; Ruokonen, I; Salonen, JT; Valkonen, VP1
Lightfoot, JD; Mahmud, W; Shekhar, A; Webber, MA1
Barakat, B; Ceciliato, R; Corinaldesi, R; Pezzilli, R1
Jiang, D; Li, L; Luo, Y; Wen, D; Yang, J1
Ishii, T; Ishikawa, CT; Miyashita, Y; Murano, T; Ozaki, H; Shirai, K; Toyoda, A1
Montaner, J1
Antonopoulos, S; Filioti, K; Giannoulis, G; Karamanolis, D; Kokkoris, S; Mikros, S; Protopsaltis, J1
Forslid, A; Kornerup-Hansen, A; Kovanen, P; Liuba, P; Paakkari, I; Pentikäinen, M; Persson, K; Pesonen, E; Østergård, G1
Arutiunov, GP; Daĭter, II; Kartseva, TP; Malanichev, RV; Marfunina, AA; Nakhaev, VI; Rozanov, AV; Rylova, AK; Stepanova, LV; Voevodina, NIu1
Dobrzycki, S; Kamiński, KA; Kralisz, P; Kuklińska, AM; Modrzejewski, W; Musiał, WJ; Sobkowicz, B; Stec, S; Wojtkowska, I1
Christensen, M; Greco, A; Lipschutz, JH; Madaio, MP; Snyder, RW; Su, AW1
Blazing, MA; Braunwald, E; Califf, RM; de Lemos, JA; Morrow, DA; Rifai, N; Sabatine, MS; Shui, A; Wiviott, SD1
Chudy, B; Lata, S1
Alvarez-Sabín, J; Chacón, P; Hereu, P; Krupinski, J; Millán, M; Molina, CA; Montaner, J; Quintana, M; Rubio, F1
D'Costa, D; Dorrian, S; Mahmoud, K1
Catovsky, D; Clutterbuck, RD; DeLord, C; Millar, JL; Newman, A; Powles, RL1
Clutterbuck, RD; Millar, JL; Newman, A; Powles, RL1
Gorrie, MJ; MacGregor, MS; Rodger, RS1
Catovsky, D; Clutterbuck, RD; Millar, JL; Newman, A; Powles, RL1
Catovsky, D; Clutterbuck, RD; Jarman, M; Millar, BC; Millar, JL; Newman, A; Powles, RL1
Barsotti, A; Barsotti, L; Di Napoli, P; Maggi, A; Palka, G; Spina, R; Stuppia, L; Taccardi, AA; Vianale, G1
Ersoy, FF; Süleymanlar, G; Tuncer, M; Yakupoğlu, G1
Asplund, K; Jonsson, N1
Kirisits, W; Kotanko, P; Skrabal, F1
Gaw, A1
Böhm, M; Hamm, CW; Heeschen, C; Laufs, U; Snapinn, S; White, HD1
Agay, D; Duhamel, O; Faure, D; Gislon, J; Legroux, P; Liautard, J; Pariente, EA; Ramdani, M; Schmitt, AM1
Bauret, P; Blanc, P; Couderc, M; Larrey, D; Michel, H; Rouillon, JM1
Ballaré, M; Bordin, G; Campanini, M; Catania, E; Monteverde, A; Zaccala, G1
Chousterman, M; Lons, T1

Reviews

3 review(s) available for simvastatin and Acute Disease

ArticleYear
Acute pancreatitis.
    Current opinion in gastroenterology, 2015, Volume: 31, Issue:5

    Topics: Acute Disease; Cholecystectomy; Combined Modality Therapy; Drainage; Energy Intake; Enteral Nutrition; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intubation, Gastrointestinal; Pancreatitis; Patient Readmission; Risk Factors; Severity of Illness Index; Sex Factors; Simvastatin; Time Factors; United States

2015
Treatment with statins in the acute phase of ischemic stroke.
    Expert review of neurotherapeutics, 2005, Volume: 5, Issue:2

    Topics: Acute Disease; Animals; Cardiology; Clinical Trials as Topic; Expert Testimony; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Attack, Transient; Neuroprotective Agents; Observation; Simvastatin; Treatment Outcome

2005
Healthy ageing: addressing acute coronary syndrome?
    European heart journal, 2001, Volume: 3 Suppl N

    Topics: Acute Disease; Adult; Age Factors; Aged; Aging; Australia; Coronary Disease; Endothelium, Vascular; Evidence-Based Medicine; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; New Zealand; Pravastatin; Risk Factors; Sex Factors; Simvastatin; Syndrome; United States

2001

Trials

9 trial(s) available for simvastatin and Acute Disease

ArticleYear
Cardiovascular outcomes and their relationships to lipoprotein components in patients with and without chronic kidney disease: results from the IDEAL trial.
    Journal of internal medicine, 2010, Volume: 267, Issue:6

    Topics: Acute Disease; Aged; Anticholesteremic Agents; Atorvastatin; Biomarkers; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Heart Arrest; Heptanoic Acids; Humans; Kidney Failure, Chronic; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Pyrroles; Regression Analysis; Simvastatin

2010
Lipid-lowering efficacy and safety of varying doses of Simvastatin in patients with early stage acute coronary syndromes: one-year follow-up study.
    Chinese medical journal, 2003, Volume: 116, Issue:6

    Topics: Acute Disease; Aged; Cholesterol; Cholesterol, LDL; Coronary Disease; Female; Follow-Up Studies; Humans; Hypolipidemic Agents; Male; Middle Aged; Simvastatin

2003
Asymmetrical dimethylarginine (ADMA) and risk of acute coronary events. Does statin treatment influence plasma ADMA levels?
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Acute Disease; Adult; Aged; Arginine; Atorvastatin; Biomarkers; Blood Glucose; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Finland; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; Prospective Studies; Pyrroles; Risk Factors; Simvastatin; Statistics as Topic; Triglycerides

2003
Changes in serum interleukin-6 and high-sensitivity C-reactive protein levels in patients with acute coronary syndrome and their responses to simvastatin.
    Heart and vessels, 2004, Volume: 19, Issue:6

    Topics: Acute Disease; Aged; Angina Pectoris; C-Reactive Protein; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Middle Aged; Myocardial Infarction; Simvastatin; Single-Blind Method; Syndrome

2004
[Effects of aggressive therapy with simvastatin in patients with acute coronary syndrome and initially normal level of LDLP cholesterol on cardiovascular outcomes (LAOKOON). Pilot randomized trial].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:9

    Topics: Acute Disease; Aged; Anti-Inflammatory Agents; Aspirin; C-Reactive Protein; Cholesterol, LDL; Coronary Disease; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pilot Projects; Simvastatin; Syndrome; Treatment Outcome

2005
Low dose rofecoxib, inflammation and prostacyclin synthesis in acute coronary syndromes.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2005, Volume: 50

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; C-Reactive Protein; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epoprostenol; Female; Follow-Up Studies; Humans; Inflammation Mediators; Interleukin-6; Lactones; Male; Middle Aged; Simvastatin; Sulfones; Syndrome

2005
Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial.
    Circulation, 2006, Jul-25, Volume: 114, Issue:4

    Topics: Acute Disease; Aged; C-Reactive Protein; Coronary Disease; Female; Follow-Up Studies; Humans; Lipoproteins, LDL; Male; Middle Aged; Prognosis; Risk Factors; Simvastatin; Survival Analysis; Tirofiban; Tyrosine

2006
Simvastatin in the acute phase of ischemic stroke: a safety and efficacy pilot trial.
    European journal of neurology, 2008, Volume: 15, Issue:1

    Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infections; Inflammation Mediators; Male; Middle Aged; Pilot Projects; Simvastatin; Stroke; Treatment Outcome

2008
Comparison of the effects of simvastatin and pravastatin on acute rejection episodes in renal transplant patients.
    Transplantation proceedings, 2000, Volume: 32, Issue:3

    Topics: Acute Disease; Adult; Anticholesteremic Agents; Female; Graft Rejection; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Kidney Transplantation; Male; Middle Aged; Pravastatin; Prospective Studies; Simvastatin

2000

Other Studies

38 other study(ies) available for simvastatin and Acute Disease

ArticleYear
Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis.
    Biochimica et biophysica acta. Molecular basis of disease, 2019, 11-01, Volume: 1865, Issue:11

    Topics: Acute Disease; Animals; Anticholesteremic Agents; Autophagy; Ceruletide; Lysosomes; Male; Membrane Fusion; Mice, Inbred C57BL; Pancreatitis; Phagosomes; Simvastatin

2019
Ameliorative role of ellagic acid against acute liver steatosis in adult zebrafish experimental model.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2021, Volume: 247

    Topics: Acute Disease; Animals; Ellagic Acid; Fatty Liver; Simvastatin; Zebrafish

2021
The impact of pretreatment with simvastatin on kidney tissue of rats with acute sepsis.
    Physiology international, 2017, Jun-01, Volume: 104, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Kidney; Male; Nephritis; Premedication; Rats; Rats, Wistar; Sepsis; Simvastatin; Treatment Outcome

2017
Simvastatin reduces VEGF and NO levels in acute stages of experimental traumatic brain injury.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34, Issue:11

    Topics: Acute Disease; Animals; Anticholesteremic Agents; Brain Injuries; Male; Nitric Oxide; Rats; Rats, Wistar; Simvastatin; Vascular Endothelial Growth Factor A

2013
Statin restores cardiac autonomic response to acute hypoxia in hypercholesterolaemia.
    European journal of clinical investigation, 2013, Volume: 43, Issue:12

    Topics: Acute Disease; Adult; Autonomic Nervous System; Baroreflex; Blood Pressure; Female; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Hypoxia; Male; Middle Aged; Reflex; Simvastatin; Young Adult

2013
Simvastatin is associated with reduced risk of acute pancreatitis: findings from a regional integrated healthcare system.
    Gut, 2015, Volume: 64, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Cohort Studies; Delivery of Health Care, Integrated; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pancreatitis; Retrospective Studies; Risk Assessment; Simvastatin; Young Adult

2015
Reduced apoptosis after acute myocardial infarction by simvastatin.
    Cell biochemistry and biophysics, 2015, Volume: 71, Issue:2

    Topics: Acute Disease; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Gene Expression Regulation; Heart Ventricles; Male; Myocardial Infarction; Organ Size; Proto-Oncogene Proteins c-bcl-2; Rabbits; Simvastatin

2015
Simvastatin Therapy in the Acute Stage of Traumatic Brain Injury Attenuates Brain Trauma-Induced Depression-Like Behavior in Rats by Reducing Neuroinflammation in the Hippocampus.
    Neurocritical care, 2017, Volume: 26, Issue:1

    Topics: Acute Disease; Animals; Behavior, Animal; Brain Injuries, Traumatic; Depression; Disease Models, Animal; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Simvastatin

2017
Simvastatin-induced rhabdomyolysis and acute renal injury.
    Blood purification, 2008, Volume: 26, Issue:4

    Topics: Acute Disease; Female; Humans; Kidney Diseases; Middle Aged; Renal Dialysis; Rhabdomyolysis; Simvastatin; Treatment Outcome

2008
Statin pretreatment in experimental acute pancreatitis.
    JOP : Journal of the pancreas, 2008, Jul-10, Volume: 9, Issue:4

    Topics: Acute Disease; Animals; Ceruletide; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Interleukin-6; Lung; Male; Pancreatitis; Peroxidase; Rats; Simvastatin; Survival Rate; Taurocholic Acid; Tumor Necrosis Factor-alpha

2008
Impaired cholesterol biosynthesis in a neuronal cell line persistently infected with measles virus.
    Journal of virology, 2009, Volume: 83, Issue:11

    Topics: Acute Disease; Animals; Cell Line, Tumor; Cholesterol; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Measles virus; Membrane Microdomains; Mice; Neuroblastoma; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Simvastatin

2009
Acute mutism: a useful lesson.
    Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:1

    Topics: Acute Disease; Adult; Aphasia, Broca; Aspirin; Cerebral Infarction; Diagnosis, Differential; Drug Therapy, Combination; Emergency Service, Hospital; Follow-Up Studies; Frontal Lobe; Humans; Magnetic Resonance Angiography; Male; Mutism; Simvastatin; Tomography, X-Ray Computed; Treatment Outcome

2011
Simvastatin improves retinal ganglion cell survival and spatial vision after acute retinal ischemia/reperfusion in mice.
    Investigative ophthalmology & visual science, 2011, Apr-20, Volume: 52, Issue:5

    Topics: Acute Disease; Animals; Behavior, Animal; Cell Count; Cell Survival; Contrast Sensitivity; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; Simvastatin; Spatial Behavior; Vision, Ocular; Visual Acuity

2011
Simvastatin ointment, a new treatment for skin inflammatory conditions.
    Journal of dermatological science, 2012, Volume: 66, Issue:2

    Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dermatitis, Irritant; Disease Models, Animal; Female; Mice; Ointments; Peroxidase; Proliferating Cell Nuclear Antigen; Simvastatin; Tetradecanoylphorbol Acetate

2012
Short-term therapy with simvastatin reduces inflammatory mediators and heart inflammation during the acute phase of experimental Chagas disease.
    Memorias do Instituto Oswaldo Cruz, 2012, Volume: 107, Issue:4

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Disease Models, Animal; Fibrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Myocarditis; Simvastatin; Time Factors; Tumor Necrosis Factor-alpha

2012
Arthrospira maxima prevents the acute fatty liver induced by the administration of simvastatin, ethanol and a hypercholesterolemic diet to mice.
    Life sciences, 2002, Apr-19, Volume: 70, Issue:22

    Topics: Acute Disease; Animals; Anticholesteremic Agents; Bacterial Proteins; Cholesterol, Dietary; Diet; Dose-Response Relationship, Drug; Ethanol; Fatty Liver; Hypercholesterolemia; Lipoproteins; Male; Mice; Simvastatin; Spirulina; Triglycerides

2002
Acute generalized exanthematous pustulosis induced by simvastatin.
    Clinical and experimental dermatology, 2003, Volume: 28, Issue:5

    Topics: Acute Disease; Anticholesteremic Agents; Drug Eruptions; Humans; Hypercholesterolemia; Male; Middle Aged; Simvastatin; Skin Diseases, Vesiculobullous

2003
Rhabdomyolysis and compartment syndrome with coadministration of risperidone and simvastatin.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Acute Disease; Adult; Antipsychotic Agents; Compartment Syndromes; Drug Interactions; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Rhabdomyolysis; Risperidone; Schizophrenia; Simvastatin

2004
Acute pancreatitis due to simvastatin therapy: increased severity after rechallenge.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:9

    Topics: Acute Disease; Aged; Anticholesteremic Agents; Emergency Medical Services; Humans; Hypercholesterolemia; Male; Pancreas; Pancreatitis; Radiography; Severity of Illness Index; Simvastatin

2004
Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2

    Topics: Acute Disease; Aged; Aryl Hydrocarbon Hydroxylases; Creatinine; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Female; Half-Life; Humans; Hypercholesterolemia; Metabolic Clearance Rate; Myoglobin; Myoglobinuria; Pyridines; Rhabdomyolysis; Simvastatin; Time Factors

2005
A case of acute pancreatitis possibly associated with combined salicylate and simvastatin treatment.
    JOP : Journal of the pancreas, 2005, May-10, Volume: 6, Issue:3

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Cholangiopancreatography, Magnetic Resonance; Coronary Disease; Drug Therapy, Combination; Humans; Hypercholesterolemia; Male; Middle Aged; Pancreatitis; Simvastatin; Tomography, X-Ray Computed

2005
Protective effects of simvastatin on coronary artery function in swine with acute infection.
    Atherosclerosis, 2006, Volume: 186, Issue:2

    Topics: Acetylcholine; Acute Disease; Animals; Bradykinin; Chlamydophila Infections; Chlamydophila pneumoniae; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Simvastatin; Swine

2006
Simvastatin protection against acute immune-mediated glomerulonephritis in mice.
    Kidney international, 2006, Volume: 69, Issue:3

    Topics: Acute Disease; Animals; Blood Urea Nitrogen; Disease Progression; Dose-Response Relationship, Drug; Female; Glomerulonephritis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Mevalonic Acid; Mice; Mice, Inbred C57BL; Proteinuria; Severity of Illness Index; Simvastatin

2006
[Acute cholestatic hepatitis caused by simvastatine in a 67-year-old patient].
    Przeglad lekarski, 2006, Volume: 63 Suppl 7

    Topics: Acute Disease; Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Humans; Hyperbilirubinemia; Jaundice, Obstructive; Male; Prednisone; Pruritus; Simvastatin; Treatment Outcome

2006
A case of recurrent rapidly progressive lower limb weakness.
    Age and ageing, 2008, Volume: 37, Issue:4

    Topics: Acute Disease; Aged; Disease Progression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leg; Male; Muscle Weakness; Rhabdomyolysis; Simvastatin

2008
The sensitivity of leukemic bone marrow to simvastatin is lost at remission: a potential purging agent for autologous bone marrow transplantation.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1995, Volume: 43, Issue:3

    Topics: Acute Disease; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Cell Death; Cells, Cultured; Humans; Leukemia, Myeloid; Lovastatin; Remission Induction; Simvastatin; Transplantation, Autologous

1995
Selective inhibition of primary acute myeloid leukaemia cell growth by simvastatin.
    Leukemia, 1994, Volume: 8, Issue:11

    Topics: Acute Disease; Bone Marrow Cells; Cell Division; Cell Survival; Cholesterol; Clone Cells; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Lovastatin; Neoplastic Stem Cells; Simvastatin; Time Factors; Tumor Cells, Cultured

1994
Acute on chronic renal failure induced by simvastatin.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:11

    Topics: Acute Disease; Cardiovascular Diseases; Chronic Disease; Humans; Lovastatin; Male; Middle Aged; Renal Insufficiency; Simvastatin

1996
A comparison of the effect of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors simvastatin, lovastatin and pravastatin on leukaemic and normal bone marrow progenitors.
    Leukemia & lymphoma, 1997, Volume: 24, Issue:5-6

    Topics: Acute Disease; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Enzyme Inhibitors; Hematopoietic Stem Cells; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lovastatin; Pravastatin; Simvastatin

1997
Inhibitory effect of simvastatin on the proliferation of human myeloid leukaemia cells in severe combined immunodeficient (SCID) mice.
    British journal of haematology, 1998, Volume: 102, Issue:2

    Topics: Acute Disease; Animals; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Female; Flow Cytometry; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasm Transplantation; Simvastatin

1998
[Simvastatin and ischemia-reperfusion damage: its effects on apoptotic myocyte death and on the endothelial expression of nitric-oxide synthetase in an experimental model of the isolated rat heart].
    Cardiologia (Rome, Italy), 1999, Volume: 44, Issue:1

    Topics: Acute Disease; Animals; Apoptosis; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Rats; Rats, Wistar; Simvastatin

1999
Does pretreatment with statins improve clinical outcome after stroke? A pilot case-referent study.
    Stroke, 2001, Volume: 32, Issue:5

    Topics: Acute Disease; Adult; Age Distribution; Aged; Case-Control Studies; Cerebral Hemorrhage; Comorbidity; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Pilot Projects; Prognosis; Retrospective Studies; Secondary Prevention; Sex Distribution; Simvastatin; Stroke; Sweden; Treatment Outcome

2001
Rhabdomyolysis and acute renal graft impairment in a patient treated with simvastatin, tacrolimus, and fusidic acid.
    Nephron, 2002, Volume: 90, Issue:2

    Topics: Acute Disease; Anti-Bacterial Agents; Drug Interactions; Female; Fusidic Acid; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Middle Aged; Rhabdomyolysis; Simvastatin; Tacrolimus; Treatment Failure

2002
Withdrawal of statins increases event rates in patients with acute coronary syndromes.
    Circulation, 2002, Mar-26, Volume: 105, Issue:12

    Topics: Acute Disease; Cholesterol; Clinical Trials as Topic; Comorbidity; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Lovastatin; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Pravastatin; Proportional Hazards Models; Risk Factors; Simvastatin; Substance Withdrawal Syndrome; Survival Rate; Treatment Outcome; Troponin; United States

2002
[Simvastatin-induced acute pancreatitis: two cases].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:12

    Topics: Acute Disease; Adult; Aged; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Pancreatitis; Simvastatin

1991
[A new case of simvastatin-induced acute pancreatitis].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:12

    Topics: Acute Disease; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Pancreatitis; Simvastatin

1991
Acute cholestatic hepatitis during simvastatin administration.
    Recenti progressi in medicina, 1991, Volume: 82, Issue:4

    Topics: Acute Disease; Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Middle Aged; Simvastatin

1991
[Simvastatin: a new drug responsible for acute pancreatitis?].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:1

    Topics: Acute Disease; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pancreatitis; Simvastatin

1991