Page last updated: 2024-08-24

simendan and Shock, Septic

simendan has been researched along with Shock, Septic in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	21 (37.50)	29.6817
2010's	30 (53.57)	24.3611
2020's	5 (8.93)	2.80

Authors

Authors	Studies
Bonderski, V; Krishnan, K; Rech, MA; Tednes, P; Wassermann, TB	1
Bruno, RR; Jung, C; Kelm, M	1
Chen, N; Cui, N; Ding, XX; Li, N; Sun, T; Wang, SH; Yu, ZB; Zhang, N	1
Couture, EJ; Nabzdyk, C; Radosevich, M	1
Fang, X; Huang, P; Jin, H; Liu, F; Ma, Z; Wang, S	1
Al-Beidh, F; Antcliffe, DB; Ashby, D; Cross, M; Gordon, AC; Mason, AJ; McAuley, DF; O'Dea, K; Orme, RML; Perkins, GD; Santhakumaran, S; Singer, M; Ward, JK	1
Baidya, DK; Bhattacharjee, S; Maitra, S; Soni, KD	1
Li, S; Wang, X	1
Chang, W; Xie, JF; Xu, JY; Yang, Y	1
Ioannou, N; Meadows, C; Nandhabalan, P; Wyncoll, D	1
Bouchez, S; Girardis, M; Guarracino, F; Herpain, A; Knotzer, J; Levy, B; Liebregts, T; Pollesello, P; Ricksten, SE; Riha, H; Rudiger, A; Sangalli, F	1
Chang, XN; Chen, Y; Dong, CM; Feng, F; Li, M; Yuan, JJ	1
Assenza, M; Bertini, E; Carrozzo, R; D'Egidio, A; Landoni, G; Marraffa, E; Morelli, A; Orecchioni, A; Pastore, A; Piemonte, F; Torraco, A; Tozzi, G; Verrigni, D	1
Coates, J; Mathieu, S	1
Ashby, D; Gordon, AC; Liu, KD; Mason, AJ; McAuley, DF; Morelli, A; Orme, RM; Perkins, GD; Singer, M	1
Li, Z; Liu, Y; Ma, S; Wang, X; Xu, W	1
Dong, S; Fang, M	1
Chen, SJ; Huang, HC; Ka, SM; Li, KY; Liaw, WJ; Tsao, CM; Wu, CC	1
Bignami, E; De Luca, M; Di Tomasso, N; Frau, G; Landoni, G; Likhvantsev, V; Lomivorotov, V; Monaco, F; Oriani, A; Putzu, A; Zangrillo, A	1
Kalbhenn, J; Reinöhl, J; Schlürmann, CN	1
Hu, MH; Ji, CL; Lai, ZZ; Meng, JB; Tian, S; Xu, XJ; Zhang, G	1
Angelini, GD; Belletti, A; Benedetto, U; Biondi-Zoccai, G; Landoni, G; Leggieri, C; Silvani, P; Zangrillo, A	1
Janssens, U	1
Ferjani, M; Hajjej, Z; Labbene, I; Meddeb, B; Morelli, A; Sellami, W	1
Ertmer, C; Morelli, A; Westphal, M	2
Abdullah, GM; Alhashemi, JA; Alotaibi, QA; Shalabi, SA	1
Blomquist, S; Cunha-Goncalves, D; Dahm, PL; Grins, E; Perez-de-Sa, V; Thörne, J	1
Blomquist, S; Cunha-Goncalves, D; Larsson, A; Perez-de-Sa, V; Thörne, J	1
Bracht, H; De Backer, D	1
de Paula, M; Delgado, MA; Esteban, A; García-Septien, J; Lorente, JA; Moscoso, A; Nin, N; Perez-Vizcaino, F; Sánchez-Ferrer, A	1
Geilfus, D; Graf, BM; Missler, G; Sinner, B; Zausig, YA; Zink, W	1
Erren, M; Ertmer, C; Köhler, G; Lange, M; Morelli, A; Rehberg, S; Seisel, J; Spiegel, HU; Su, F; Traber, DL; Van Aken, H; Vincent, JL; Westphal, M	1
Russell, JA	1
Cecchini, V; Donati, A; Ertmer, C; Ince, C; Landoni, G; Lange, M; Morelli, A; Orecchioni, A; Pelaia, P; Pietropaoli, P; Rehberg, S; Teboul, JL; Van Aken, H; Westphal, M	1
Ji, MH; Peng, YG; Wang, X; Yang, JJ	1
Bellmann, R; Bertocchi, C; Bijuklic, K; Dunzendorfer, S; Hasslacher, J; Joannidis, M; Kountchev, J	1
Inal, MT; Memiş, D; Sut, N	1
Mebazaa, A; Yilmaz, MB	1
Dong, L; Fan, Y; Ji, M; Li, GM; Li, R; Peng, YG; Wu, J; Yang, J	1
Caresta, E; Midulla, F; Moretti, C; Papoff, P; Pinto, R; Versacci, P	1
Giacomini, M; Iapichino, G; Noto, A; Palandi, A; Reali-Forster, C; Stabile, L	1
Krouzecky, A; Matejovic, M; Novak, I; Radej, J	1
Conti, G; De Castro, S; De Luca, L; Di Angelantonio, E; Morelli, A; Orecchioni, A; Pandian, NG; Pietropaoli, P; Rocco, M; Singer, M; Teboul, JL	1
Bouckaert, Y; Creteur, J; Mélot, C; Vincent, JL	1
Carbone, I; Conti, G; De Gaetano, A; Maggiore, SM; Morelli, A; Orecchioni, A; Picchini, U; Pietropaoli, P; Rocco, M; Teboul, JL; Tritapepe, L; Vieillard-Baron, A; Westphal, M	1
Carlson, RW; Emmans, L	1
De Backer, D; Radermacher, P; Taccone, FS	1
Barán, M; Canales, HS; Dubin, A; Edul, VS; Estenssoro, E; Etcheverry, G; Maskin, B; Murias, G; Pozo, MO; Sottile, JP	1
Bihari, D; Ramaswamykanive, H; Solano, TR	1
De Keulenaer, BL; Powell, BP	1
Archan, S; Toller, W	1
Ertmer, C; Pinto, BB; Rehberg, S; Westphal, M	1
Farías, J; Monteverde, E; Neira, P	1
Bickenbach, J; Bleilevens, C; Fries, M; Ince, C; Mik, EG; Rex, S; Rossaint, R	1
Konrad, D; Oldner, A; Rossi, P; Rudehill, A; Wanecek, M; Weitzberg, E	1

Reviews

12 review(s) available for simendan and Shock, Septic

Article	Year
Beyond the bundle: Clinical controversies in the management of sepsis in emergency medicine patients. The American journal of emergency medicine, 2022, Volume: 51 Topics: Angiotensin II; Ascorbic Acid; Crystalloid Solutions; Disease Management; Drug Therapy, Combination; Emergency Service, Hospital; Humans; Hydrocortisone; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan; Thiamine	2022
[Pharmaceutical therapy of infarct-related cardiogenic shock]. Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:18 Topics: Humans; Myocardial Infarction; Pharmaceutical Preparations; Shock, Cardiogenic; Shock, Septic; Simendan	2022
A Meta-Analysis of the Effects of Levosimendan on Cardiac Function and Outcomes in Patients with Sepsis. Alternative therapies in health and medicine, 2023, Volume: 29, Issue:8 Topics: Dobutamine; Humans; Hydrazones; Pyridazines; Sepsis; Shock, Septic; Simendan; Stroke Volume; Ventricular Function, Left	2023
Levosimendan does not provide mortality benefit over dobutamine in adult patients with septic shock: A meta-analysis of randomized controlled trials. Journal of clinical anesthesia, 2017, Volume: 39 Topics: Adult; Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Intensive Care Units; Norepinephrine; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan	2017
Effect of levosimendan on mortality in severe sepsis and septic shock: a meta-analysis of randomised trials. BMJ open, 2018, 03-30, Volume: 8, Issue:3 Topics: Cardiotonic Agents; Humans; Hydrazones; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan	2018
Use of Levosimendan in Intensive Care Unit Settings: An Opinion Paper. Journal of cardiovascular pharmacology, 2019, Volume: 73, Issue:1 Topics: Animals; Cardio-Renal Syndrome; Cardiotonic Agents; Critical Care; Humans; Intensive Care Units; Recovery of Function; Risk Factors; Shock, Cardiogenic; Shock, Septic; Simendan; Treatment Outcome; Vasodilator Agents	2019
Levosimendan does not reduce the mortality of critically ill adult patients with sepsis and septic shock: a meta-analysis. Chinese medical journal, 2019, May-20, Volume: 132, Issue:10 Topics: Critical Illness; Female; Humans; Male; Sepsis; Shock, Septic; Simendan	2019
BET 1: levosimendan in septic shock. Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:6 Topics: Cardiotonic Agents; Evidence-Based Emergency Medicine; Humans; Hydrazones; Pyridazines; Shock, Septic; Simendan	2014
Levosimendan reduces mortality in patients with severe sepsis and septic shock: A meta-analysis of randomized trials. Journal of critical care, 2015, Volume: 30, Issue:5 Topics: Cardiotonic Agents; Dobutamine; Female; Humans; Hydrazones; Male; Middle Aged; Norepinephrine; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan	2015
The effect of vasoactive drugs on mortality in patients with severe sepsis and septic shock. A network meta-analysis of randomized trials. Journal of critical care, 2017, Volume: 37 Topics: Arginine Vasopressin; Cardiotonic Agents; Dobutamine; Dopamine; Epinephrine; Humans; Hydrazones; Network Meta-Analysis; Norepinephrine; Odds Ratio; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan; Treatment Outcome; Vasoconstrictor Agents; Vasopressins	2017
Levosimendan: current status and future prospects. Current opinion in anaesthesiology, 2008, Volume: 21, Issue:1 Topics: Acute Disease; Adrenergic beta-Antagonists; Cardiotonic Agents; Heart Failure; Humans; Hydrazones; Postoperative Complications; Pyridazines; Shock, Septic; Simendan; Ventricular Dysfunction, Right	2008
Role of levosimendan in sepsis and septic shock. Current opinion in anaesthesiology, 2008, Volume: 21, Issue:2 Topics: Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Endotoxemia; Heart Failure; Humans; Hydrazones; Potassium Channels; Pyridazines; Sepsis; Shock, Septic; Simendan	2008

Trials

12 trial(s) available for simendan and Shock, Septic

Article	Year
Efficacy of Levosimendan in the Treatment of Patients With Severe Septic Cardiomyopathy. Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:3 Topics: Cardiomyopathies; Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Norepinephrine; Prospective Studies; Pyridazines; Sepsis; Shock, Septic; Simendan; Single-Blind Method; Stroke Volume; Ventricular Function, Left	2023
Levosimendan in septic shock in patients with biochemical evidence of cardiac dysfunction: a subgroup analysis of the LeoPARDS randomised trial. Intensive care medicine, 2019, Volume: 45, Issue:10 Topics: Aged; Biomarkers; Chemokine CCL2; Double-Blind Method; Female; Heart Diseases; HSP90 Heat-Shock Proteins; Humans; Intensive Care Units; Interleukin-10; Interleukin-6; Interleukin-8; Male; Middle Aged; Natriuretic Peptide, Brain; Organ Dysfunction Scores; Peptide Fragments; Prognosis; Shock, Septic; Simendan; Troponin I; United Kingdom	2019
Effect of small-dose levosimendan on mortality rates and organ functions in Chinese elderly patients with sepsis. Clinical interventions in aging, 2017, Volume: 12 Topics: Aged; China; Double-Blind Method; Female; Hospital Mortality; Humans; Hydrazones; Intensive Care Units; Length of Stay; Male; Organ Dysfunction Scores; Prospective Studies; Pyridazines; Shock, Septic; Simendan	2017
Effects of levosimendan on mitochondrial function in patients with septic shock: a randomized trial. Biochimie, 2014, Volume: 102 Topics: Aged; Aged, 80 and over; Electron Transport Complex I; Female; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Mitochondria; Oxidative Stress; Pyridazines; Reactive Oxygen Species; Shock, Septic; Simendan; Superoxide Dismutase	2014
An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial. Trials, 2014, Jun-02, Volume: 15 Topics: Adult; Cardiac Output; Cardiotonic Agents; Critical Care; Diaphragm; Double-Blind Method; Follow-Up Studies; Humans; Hydrazones; Kidney; Multiple Organ Failure; Pyridazines; Regional Blood Flow; Research Design; Shock, Septic; Simendan	2014
[Effects of levosimendan on hemodynamics and cardiac function in patients with septic shock]. Zhonghua wei zhong bing ji jiu yi xue, 2014, Volume: 26, Issue:10 Topics: Cardiac Output; Central Venous Pressure; Extravascular Lung Water; Fluid Therapy; Hemodynamics; Humans; Hydrazones; Norepinephrine; Prospective Studies; Pyridazines; Shock, Septic; Simendan; Stroke Volume; Treatment Outcome	2014
Levosimendan Versus Dobutamine in Myocardial Injury Patients with Septic Shock: A Randomized Controlled Trial. Medical science monitor : international medical journal of experimental and clinical research, 2016, May-03, Volume: 22 Topics: Biomarkers; Demography; Dobutamine; Fatty Acid-Binding Proteins; Female; Hemodynamics; Humans; Hydrazones; Lactic Acid; Male; Middle Aged; Multivariate Analysis; Myocardium; Natriuretic Peptide, Brain; Pyridazines; Regression Analysis; Shock, Septic; Simendan; Troponin I; Ventricular Function, Left	2016
Effects of Levosimendan on Cellular Metabolic Alterations in Patients With Septic Shock: A Randomized Controlled Pilot Study. Shock (Augusta, Ga.), 2017, Volume: 48, Issue:3 Topics: Adult; Aged; Dobutamine; Double-Blind Method; Humans; Hydrazones; Male; Middle Aged; Pilot Projects; Pyridazines; Shock, Septic; Simendan	2017
Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study. Critical care (London, England), 2010, Volume: 14, Issue:6 Topics: Aged; Double-Blind Method; Female; Humans; Hydrazones; Male; Microcirculation; Middle Aged; Mouth Floor; Prospective Studies; Pyridazines; Resuscitation; Shock, Septic; Simendan	2010
The effects of levosimendan vs dobutamine added to dopamine on liver functions assessed with noninvasive liver function monitoring in patients with septic shock. Journal of critical care, 2012, Volume: 27, Issue:3 Topics: Cardiotonic Agents; Coloring Agents; Dobutamine; Dopamine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrazones; Indocyanine Green; Liver Circulation; Liver Function Tests; Male; Metabolic Clearance Rate; Microcirculation; Middle Aged; Prospective Studies; Pyridazines; Regional Blood Flow; Shock, Septic; Simendan	2012
Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression. Intensive care medicine, 2005, Volume: 31, Issue:5 Topics: Cardiac Output, Low; Cardiotonic Agents; Female; Gastric Mucosa; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Shock, Septic; Simendan; Statistics, Nonparametric	2005
Effects of levosimendan on right ventricular afterload in patients with acute respiratory distress syndrome: a pilot study. Critical care medicine, 2006, Volume: 34, Issue:9 Topics: Aged; Female; Humans; Hydrazones; Hypertension, Pulmonary; Infusions, Intravenous; Male; Oxygen; Pilot Projects; Prospective Studies; Pyridazines; Respiratory Distress Syndrome; Shock, Septic; Simendan; Stroke Volume; Systole; Vascular Resistance; Vasodilator Agents; Ventricular Dysfunction, Right	2006

Other Studies

32 other study(ies) available for simendan and Shock, Septic

Article	Year
Levosimendan And Septic Cardiomyopathy: A Key That May Have Found Its Lock? Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:3 Topics: Cardiomyopathies; Cardiotonic Agents; Humans; Hydrazones; Shock, Septic; Simendan	2023
Refractory septic shock: our pragmatic approach. Critical care (London, England), 2018, Sep-19, Volume: 22, Issue:1 Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Cardiotonic Agents; Extracorporeal Membrane Oxygenation; Humans; Immunoglobulins; Multiple Organ Failure; Renal Replacement Therapy; Serum Albumin, Human; Shock, Septic; Simendan; Treatment Outcome; Vasoconstrictor Agents	2018
Effects and mechanism analysis of combined infusion by levosimendan and vasopressin on acute lung injury in rats septic shock. Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3 Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Cardiovascular Agents; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Female; HMGB1 Protein; Hydrazones; Lung; Nitrogen Oxides; Norepinephrine; Pyridazines; Rats; Shock, Septic; Simendan; Vasopressins	2014
Levosimendan attenuates multiple organ injury and improves survival in peritonitis-induced septic shock: studies in a rat model. Critical care (London, England), 2014, Nov-29, Volume: 18, Issue:6 Topics: Animals; Disease Models, Animal; Hydrazones; Infusions, Intravenous; Male; Multiple Organ Failure; Oxidative Stress; Peritonitis; Pyridazines; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Simendan; Survival Rate	2014
[Levosimendan for septic shock with takotsubo cardiomyopathy]. Der Anaesthesist, 2016, Volume: 65, Issue:1 Topics: Abdomen, Acute; Aged, 80 and over; Cardiotonic Agents; Female; Hemodynamics; Humans; Hydrazones; Ileus; Peritonitis; Pyridazines; Radionuclide Ventriculography; Shock, Septic; Simendan; Takotsubo Cardiomyopathy	2016
[Levosimendan-no effect on multiorgan failure in septic shock]. Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2017, Volume: 112, Issue:3 Topics: Cardiotonic Agents; Humans; Hydrazones; Multiple Organ Failure; Pyridazines; Shock, Septic; Simendan	2017
Levo is in the air: take a deep breath! Critical care medicine, 2008, Volume: 36, Issue:6 Topics: Administration, Inhalation; Adult; Animals; Cardiotonic Agents; Disease Models, Animal; Female; Hemodynamics; Humans; Hydrazones; Multiple Organ Failure; Postoperative Complications; Pyridazines; Rats; Respiratory Distress Syndrome; Risk Factors; Shock, Septic; Simendan	2008
Calcium sensitizing in sepsis: is levosimendan on the right path? Critical care medicine, 2008, Volume: 36, Issue:6 Topics: Animals; Calcium; Cardiotonic Agents; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Hydrazones; Microcirculation; Mouth Mucosa; Norepinephrine; Oxygen; Phosphodiesterase Inhibitors; Pyridazines; Rats; Regional Blood Flow; Shock, Septic; Simendan	2008
Levosimendan vs dobutamine in septic shock. Journal of critical care, 2009, Volume: 24, Issue:3 Topics: APACHE; Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Lactic Acid; Pyridazines; Randomized Controlled Trials as Topic; Shock, Septic; Simendan	2009
Inotropic support during experimental endotoxemic shock: part I. The effects of levosimendan on splanchnic perfusion. Anesthesia and analgesia, 2009, Volume: 109, Issue:5 Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy; Disease Models, Animal; Fluid Therapy; Heart Rate; Hemodynamics; Hydrazones; Hypotension; Lactic Acid; Lipopolysaccharides; Liver Circulation; Oxygen; Pyridazines; Regional Blood Flow; Shock, Septic; Simendan; Splanchnic Circulation; Swine; Time Factors; Vascular Resistance	2009
Inotropic support during experimental endotoxemic shock: part II. A comparison of levosimendan with dobutamine. Anesthesia and analgesia, 2009, Volume: 109, Issue:5 Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy; Disease Models, Animal; Dobutamine; Drug Therapy, Combination; Fluid Therapy; Heart Rate; Hemodynamics; Hydrazones; Hypotension; Lactic Acid; Lipopolysaccharides; Liver Circulation; Norepinephrine; Oxygen; Pyridazines; Regional Blood Flow; Shock, Septic; Simendan; Splanchnic Circulation; Swine; Time Factors; Vascular Resistance	2009
Levosimendan in early sepsis: when good ideas give poor results. Anesthesia and analgesia, 2009, Volume: 109, Issue:5 Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy; Fluid Therapy; Heart Rate; Hemodynamics; Humans; Hydrazones; Lactic Acid; Liver Circulation; Oxygen; Pyridazines; Regional Blood Flow; Shock, Septic; Simendan; Splanchnic Circulation; Time Factors; Vascular Resistance	2009
Levosimendan increases portal blood flow and attenuates intestinal intramucosal acidosis in experimental septic shock. Shock (Augusta, Ga.), 2010, Volume: 34, Issue:3 Topics: Acidosis; Animals; Cardiotonic Agents; Cell Hypoxia; Drug Evaluation, Preclinical; Escherichia coli Infections; Heart Rate; Hydrazones; Intestinal Mucosa; Liver Circulation; Microcirculation; Models, Animal; Peritonitis; Portal System; Pyridazines; Shock, Septic; Simendan; Swine; Vasodilator Agents	2010
Direct cardiac effects of dobutamine, dopamine, epinephrine, and levosimendan in isolated septic rat hearts. Shock (Augusta, Ga.), 2010, Volume: 34, Issue:3 Topics: Animals; Cardiotonic Agents; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Heart; Heart Rate; Hydrazones; In Vitro Techniques; Male; Models, Animal; Myocardium; Oxygen Consumption; Peritonitis; Pyridazines; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Simendan; Therapeutic Equivalency	2010
Effects of combined arginine vasopressin and levosimendan on organ function in ovine septic shock. Critical care medicine, 2010, Volume: 38, Issue:10 Topics: Animals; Arginine Vasopressin; Blood Gas Analysis; Blood Pressure; Drug Therapy, Combination; Hydrazones; Lung; Myocardial Contraction; Norepinephrine; Pulmonary Wedge Pressure; Pyridazines; Sheep; Shock, Septic; Simendan; Vascular Resistance; Vasoconstrictor Agents; Water-Electrolyte Balance	2010
Vasopressin, levosimendan, and cardiovascular function in septic shock. Critical care medicine, 2010, Volume: 38, Issue:10 Topics: Animals; Arginine Vasopressin; Cardiovascular System; Drug Therapy, Combination; Hydrazones; Norepinephrine; Pyridazines; Sheep; Shock, Septic; Simendan; Vasoconstrictor Agents	2010
Combined arginine vasopressin and levosimendan: a promising therapy for septic shock. Critical care medicine, 2011, Volume: 39, Issue:4 Topics: Animals; Arginine Vasopressin; Drug Therapy, Combination; Humans; Hydrazones; Pyridazines; Sheep; Shock, Septic; Simendan; Vasodilator Agents	2011
Levosimendan inhibits release of reactive oxygen species in polymorphonuclear leukocytes in vitro and in patients with acute heart failure and septic shock: a prospective observational study. Critical care (London, England), 2011, Jul-12, Volume: 15, Issue:4 Topics: Acute Disease; Aged; Aged, 80 and over; Austria; Cardiotonic Agents; Female; Flow Cytometry; Heart Failure; Humans; Hydrazones; In Vitro Techniques; Male; Middle Aged; Neutrophils; Prospective Studies; Pyridazines; Reactive Oxygen Species; Shock, Septic; Simendan	2011
In vivo and in vitro evidence for pleiotropic effects of levosimendan in the intensive care setting. Critical care (London, England), 2011, Aug-18, Volume: 15, Issue:4 Topics: Cardiotonic Agents; Female; Heart Failure; Humans; Hydrazones; Male; Neutrophils; Pyridazines; Reactive Oxygen Species; Shock, Septic; Simendan	2011
Effects of combined levosimendan and vasopressin on pulmonary function in porcine septic shock. Inflammation, 2012, Volume: 35, Issue:3 Topics: Animals; Arginine Vasopressin; Blood Pressure; Drug Therapy, Combination; Female; Hemodynamics; HMG-Box Domains; Hydrazones; Inflammation; Interleukin-6; Lactic Acid; Lung; Nitrates; Nitrites; Norepinephrine; Peritonitis; Pulmonary Artery; Pulmonary Gas Exchange; Pyridazines; Random Allocation; Respiratory Physiological Phenomena; Shock, Septic; Simendan; Swine	2012
Beneficial effects of levosimendan in infants with sepsis-associated cardiac dysfunction: report of 2 cases. Pediatric emergency care, 2012, Volume: 28, Issue:10 Topics: Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Humans; Hydrazones; Infant; Infusions, Intravenous; Male; Myocardial Contraction; Pyridazines; Shock, Septic; Simendan	2012
Levosimendan in septic cardiac failure. Intensive care medicine, 2005, Volume: 31, Issue:1 Topics: Adult; Aged; Cardiotonic Agents; Female; Hemodynamics; Humans; Hydrazones; Male; Myocardial Infarction; Pyridazines; Shock, Septic; Simendan	2005
Successful reversal of resistent hypodynamic septic shock with levosimendan. Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:1 Topics: Adult; Cardiac Output; Cardiomyopathies; Cardiotonic Agents; Female; Humans; Hydrazones; Immunocompromised Host; Pyridazines; Shock, Septic; Simendan	2005
Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression. Intensive care medicine, 2006, Volume: 32, Issue:5 Topics: Belgium; Cardiac Output, Low; Humans; Hydrazones; Pyridazines; Shock, Septic; Simendan; Vasodilator Agents	2006
A new horizon in the treatment of right ventricular failure and pulmonary hypertension associated with acute respiratory distress syndrome? Critical care medicine, 2006, Volume: 34, Issue:9 Topics: Humans; Hydrazones; Hypertension, Pulmonary; Pyridazines; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Shock, Septic; Simendan; Vasodilator Agents; Ventricular Dysfunction, Right	2006
Levosimendan in septic shock: another piece in the puzzle, but many pieces are still lacking. Intensive care medicine, 2007, Volume: 33, Issue:3 Topics: Animals; Cardiotonic Agents; Hydrazones; Pyridazines; Sheep; Shock, Septic; Simendan; Splanchnic Circulation	2007
Effects of levosimendan and dobutamine in experimental acute endotoxemia: a preliminary controlled study. Intensive care medicine, 2007, Volume: 33, Issue:3 Topics: Acidosis; Analysis of Variance; Animals; Cardiotonic Agents; Dobutamine; Endotoxemia; Hydrazones; Lactic Acid; Oxygen; Prospective Studies; Pyridazines; Random Allocation; Sheep; Shock, Septic; Simendan; Splanchnic Circulation	2007
Myocardial depression associated with pneumococcal septic shock reversed by levosimendan. Anaesthesia and intensive care, 2007, Volume: 35, Issue:3 Topics: Aged; Cardiac Output, Low; Female; Humans; Hydrazones; Pneumococcal Infections; Pyridazines; Shock, Septic; Simendan; Vasodilator Agents	2007
Levosimendan in septic shock: a case series. British journal of anaesthesia, 2007, Volume: 99, Issue:3 Topics: Cardiotonic Agents; Humans; Hydrazones; Pyridazines; Shock, Septic; Simendan	2007
[Paediatric use of levosimendan in septic shock]. Anales de pediatria (Barcelona, Spain : 2003), 2008, Volume: 68, Issue:5 Topics: Adolescent; Humans; Hydrazones; Male; Pyridazines; Shock, Septic; Simendan; Vasodilator Agents	2008
Levosimendan but not norepinephrine improves microvascular oxygenation during experimental septic shock. Critical care medicine, 2008, Volume: 36, Issue:6 Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Fluid Therapy; Hemodynamics; Hydrazones; Lactic Acid; Male; Microcirculation; Mouth Mucosa; Norepinephrine; Oxygen; Pyridazines; Rats; Rats, Sprague-Dawley; Shock, Septic; Simendan; Vasodilator Agents	2008
Effects of levosimendan, a novel inotropic calcium-sensitizing drug, in experimental septic shock. Critical care medicine, 2001, Volume: 29, Issue:11 Topics: Animals; Calcium; Cardiotonic Agents; Escherichia coli Infections; Female; Hemodynamics; Hydrazones; Male; Myocardial Contraction; Pyridazines; Shock, Septic; Simendan; Swine	2001